Prime Pursuit

John Garrett
  • 4.5 (2)
  • Health & Fitness
  • Weekly

Prime Pursuit is a podcast about building a stronger body, a sharper mind, and a life with deeper purpose. Hosted by John Garrett, Prime Pursuit explores the intersection of health, fitness, longevity, mindset, faith, and personal growth—without hype, extremes, or unnecessary complexity. Episodes break down the ideas, treatments, trends, habits, and conversations shaping modern health and wellness, from strength training, hormones, nutrition, recovery, and emerging therapies to mental resilience, relationships, purpose, and Christian faith. Some episodes go deep into the science. Others feature conversations with experts, entrepreneurs, clinicians, athletes, and people with stories worth hearing. But every episode comes back to the same question: **How do we become better physically, mentally, and spiritually—and make the years ahead some of our best?** This isn't about chasing perfection. It's about pursuing your prime. **Prime Pursuit — Better Health. Deeper Purpose.**

  1. 13h ago

    Beyond Stem Cells: Secretomes, Cellular Repair & Longevity | Sanjiv Lal

    What if the key to healthier aging isn't just replacing damaged cells, but restoring the way our cells communicate? In this episode of Prime Pursuit, John Garrett sits down with Sanjiv Lal, founder of Cell Factor and co-founder of Regen Therapy, to explore the emerging science of regenerative medicine, cellular communication, and longevity. Sanjiv shares his remarkable personal journey—from working in pharmaceutical sciences and molecular diagnostics to facing serious health challenges of his own. After experiencing kidney dysfunction, metabolic problems, and declining health, he began exploring regenerative medicine and the potential of secretomes: biological signaling molecules that help cells communicate. That experience changed the direction of his life and inspired his mission to rethink how we approach aging, recovery, and long-term health. In this conversation, we explore: Beyond Stem Cells: What secretomes are and how cellular signaling could influence the future of regenerative medicine. Cellular Health & Longevity: Why communication between cells matters for inflammation, tissue repair, and healthy aging. Mitochondrial Function: The connection between cellular energy, recovery, and overall health. Peptides & Emerging Therapies: Sanjiv's experience with Cell Factor, SS-31, MOTS-c, and other longevity-focused interventions. Healthspan, Lifespan & Joyspan: Why living longer should also mean living healthier, staying active, and enjoying life. Taking Ownership of Your Health: Why nutrition, exercise, sleep, preventive care, and working with knowledgeable healthcare providers remain essential. The Future of Healthcare: How personalized diagnostics, regenerative science, and patient-centered medicine could reshape the way we approach wellness. John and Sanjiv also have a candid conversation about the challenges facing modern healthcare, the growing problem of polypharmacy, and why being proactive about our health matters more than ever. One of the biggest takeaways? Our goal shouldn't simply be to add more years to our lives. It should be to add more life, health, and purpose to those years. The possibilities of regenerative medicine are exciting, but many of these emerging technologies still require rigorous human clinical research to establish their safety and effectiveness. This conversation is about more than stem cells or peptides. It's about understanding the human body, taking responsibility for our health, and pursuing a future where we don't just live longer—we live better. Better Health. Deeper Purpose. Learn more about Sanjiv's work: Cell Factor: https://cell.health/ RegenTherapy: https://regentherapy.com Disclaimer: This episode is for educational and informational purposes only. Views and personal experiences discussed are those of the speakers and do not establish that experimental regenerative therapies are safe or effective. Nothing in this episode should be considered individualized medical advice. Consult a qualified healthcare professional regarding treatment decisions.

  2. 6d ago

    Modafinil: The Smart Drug That Might Not Make You Smarter

    Is modafinil a real cognitive enhancer or simply a powerful wakefulness medication? John Garrett explores what clinical trials actually show, the military research on fatigue, the risks of prescription stimulants, and why more hours awake don't necessarily mean a better life. Check out Peptides Explained everywhere you listen to podcasts

  3. Oct 21

    The Silent Killer in Your Kitchen? Seed Oils, Inflammation & What to Cook With Instead with Cherie Calbom

    Seed oils may be hiding in more of your everyday foods than you realize. In this episode of Peptides Explained, host John talks with Cherie Calbom, MS—known as the Juice Lady—about seed oils, cooking fats, inflammation, and how to make more informed choices at the grocery store and when dining out.Cherie discusses how common seed oils are processed, why she recommends checking ingredient labels, and which alternatives she uses, including olive oil, avocado oil, coconut oil, ghee, and beef tallow. They also talk about omega-6 and omega-3 balance, cooking with different fats, and practical ways to make food swaps without giving up flavor.The conversation explores the history of seed oils and changing ideas about dietary fat and cholesterol. Cherie shares tips for spotting oils in packaged foods and describes resources for people who want to learn more, including her book The Truth About Seed Oils. Topics include: seed oils, cooking fats, inflammation, omega-6 and omega-3, food labels, nutrition, and healthy cooking.

  4. Oct 19

    The Peptide Revolution: What the Hell Is Going On?

    Peptides are making headlines, pharmaceutical companies are suing sellers, and regulators are debating access. What does the science actually show? In this Prime Pursuit episode, we challenge both the marketing hype and the alarmist narratives, unpack the retatrutide controversy, and ask what informed medical freedom should look like. For deeper molecule-by-molecule analysis, listen to Peptides Explained. Disclosure: The host has affiliate relationships with peptide-related companies and may earn referral commissions. #PrimePursuit #Peptides #Retatrutide #MedicalInnovation #Longevity #GLP1 #HealthOptimization

  5. Oct 14

    The Ultimate Recovery Protocol: Training for Strength, Longevity & Purpose

    What does it actually mean to train for your prime years?   In this episode of Prime Pursuit, John breaks down the training and recovery philosophy he is using to stay strong, mobile, conditioned, resilient, and useful for decades to come. The current framework includes Brazilian jiu jitsu three to four times per week, a dedicated strength day, a Murph-inspired strength-endurance session, and Zone 2 cardio used strategically to build aerobic capacity without turning every workout into another high-fatigue event.   But this episode goes beyond sets, reps, and heart-rate zones. Recovery also means sleep, nutrition, mobility, stress management, prayer, Scripture, reflection, and learning when discipline means pushing—and when it means backing off.   The goal isn't specialized fitness. It's capability.   Better health. Deeper purpose.

  6. Oct 12

    What the Heck Is Visceral Fat? (And Why People Keep Getting It Wrong)

    Everyone keeps calling belly fat "visceral fat." That is not how anatomy works. In this crossover episode, John breaks down the difference between visceral and subcutaneous fat, why visceral adipose tissue matters metabolically, how it is actually measured, what waist circumference can and cannot tell you, and what the evidence says about GLP-1 therapies and tesamorelin.

  7. Oct 7

    Why I Get Into Freezing Water Five Days a Week

    David Goggins has a line about BUD/S training: "Many dreams die while suffering." The men who quit were not necessarily weak or lazy. They reached a moment when immediate relief became more attractive than the future they said they wanted. In this follow-up to The Warrior and the Poet, John explains why he uses cold-water immersion four to five times per week for recovery, energy, stress-response training, and mental resilience. He walks through what cold exposure may do for soreness, alertness, mood, catecholamines, brown fat, metabolism, inflammation, and perceived recovery—without turning the episode into a biology lecture or pretending an ice bath cures everything. You'll also hear why cold exposure does not simply "lower cortisol," why plunging immediately after lifting may interfere with muscle growth, how to think about Huberman's eleven-minutes-per-week framework, and why colder is not automatically better. The larger lesson is not about becoming good at sitting in cold water. It is about learning that discomfort is not an emergency—and practicing the ability to stay composed when every reflex tells you to escape. Better health. Deeper purpose. This is Prime Pursuit.

  8. Oct 5

    How to Actually Lose Fat After 40: Hormones, Muscle, GLP-1s & What Actually Works

    Most people already know the basics of fat loss: eat fewer calories, move more, and exercise consistently. The problem is that knowing the basics and sustaining them are two very different things—especially in your 40s, 50s, and beyond.   In this episode of Prime Pursuit, John breaks down the practical factors that determine whether fat loss actually sticks: muscle preservation, protein intake, hormone health, sleep, alcohol, GLP-1 medications, creatine, vitamin D, peptides, daily movement, food environment, and long-term maintenance.   This is not another "eat less, move more" lecture. It is a realistic framework for losing excess fat while protecting strength, health, and capability—and for building a body you can actually maintain.   The episode also explores a Christian view of physical stewardship: your body is not an idol, but it is something you have been entrusted to care for so you can serve, protect, work, and answer the call when your family needs you.   Better health. Deeper purpose.

See All (18)

Ratings & Reviews

4.5
out of 5
2 Ratings

About

Prime Pursuit is a podcast about building a stronger body, a sharper mind, and a life with deeper purpose. Hosted by John Garrett, Prime Pursuit explores the intersection of health, fitness, longevity, mindset, faith, and personal growth—without hype, extremes, or unnecessary complexity. Episodes break down the ideas, treatments, trends, habits, and conversations shaping modern health and wellness, from strength training, hormones, nutrition, recovery, and emerging therapies to mental resilience, relationships, purpose, and Christian faith. Some episodes go deep into the science. Others feature conversations with experts, entrepreneurs, clinicians, athletes, and people with stories worth hearing. But every episode comes back to the same question: **How do we become better physically, mentally, and spiritually—and make the years ahead some of our best?** This isn't about chasing perfection. It's about pursuing your prime. **Prime Pursuit — Better Health. Deeper Purpose.**

Information

  • Creator
    John Garrett
  • Years Active
    2026
  • Episodes
    18
  • Rating
    Explicit
  • Copyright
    © 2026
  • Show Website
    Prime Pursuit

You Might Also Like