Evolution of Medicine Podcast

Functional Forum
  • 4.8 (98)
  • Alternative Health
  • Updated Biweekly

Hear from the experts that are driving the evolution of medicine.

  1. 1d ago ·  Video

    The Pathobiome: Stealth Infections and the Brain

    In this episode, host James Maskell sits down with Nikki Schultek, founding director of the Pathobiome Research Center at the Philadelphia College of Osteopathic Medicine and founder of the Alzheimer's Pathobiome Initiative, a global research consortium. Schultek's path into this work began with her own illness 11 years ago — a multi-system chronic condition driven by a tick bite and co-infections including Chlamydia pneumoniae, which went misdiagnosed by 12 specialists for a year before Dr. Charles Stratton at Vanderbilt identified and treated the underlying infections, restoring her to roughly 95% of her former health. That experience, and the fear of not watching her young children grow up, led her to found Intracell Research Group and later become what she calls a "collaboration architect" — connecting siloed researchers across immunology, microbiology, neuropathology, and epidemiology who study different pathogens (herpesviruses, Chlamydia, Borrelia, Bartonella, fungi, syphilis) but rarely collaborate with one another. The conversation covers the evidence linking infection to Alzheimer's disease: animal studies showing pathogens like C. pneumoniae can induce amyloid-like plaques in wild-type mice; the historical near-miss in which Alzheimer's disease could have been named after Dr. Oscar Fischer, who described bacterial-colony-like structures in tangles and plaques during the pre-antibiotic syphilis era; and emerging research suggesting amyloid and tau may act as innate immune "firefighters" responding to infection rather than purely destructive proteins. Schultek highlights her consortium's 2023 landmark paper in Alzheimer's & Dementia, which catalogued 86 case reports of infectious dementias reversed through targeted antimicrobial treatment. Maskell and Schultek also discuss the heterogeneity of individual cases — from periodontal pathogens like Porphyromonas gingivalis to tick-borne co-infections — and the need for precision, patient-specific approaches that account for genetics, exposome, and hormonal factors. The episode closes with a discussion of what's needed to move the field forward: greater federal and philanthropic funding, better multi-pathogen and host-biomarker testing, industry investment in targeted (rather than broad-spectrum) antimicrobial therapies, and expanded insurance coverage — particularly for PANS/PANDAS families currently priced out of diagnostic testing. - - - - - About the Guest: Nikki Schultek is the founding director of the Pathobiome Research Center at the Philadelphia College of Osteopathic Medicine and founder of the Alzheimer's Pathobiome Initiative, a global research consortium studying the role of infectious agents in neurodegenerative, neurological, and neuropsychiatric disease. A former patient whose own multi-system chronic illness was driven by tick-borne and intracellular infections, she now works as a "collaboration architect," bringing together researchers across immunology, microbiology, epidemiology, and neuropathology to advance infection-associated chronic illness research. She is co-lead author of the 2023 landmark paper on the Alzheimer's Pathobiome Initiative published in Alzheimer's & Dementia. - - - - - Social Handles: Website: https://www.jamesmaskell.com/ X: https://x.com/mrjamesmaskell Instagram: https://www.instagram.com/mrjamesmaskell Facebook: https://www.facebook.com/jamesedwardmaskell/ Linkedin: https://www.linkedin.com/in/jamesmaskell Youtube: https://www.youtube.com/FunctionalForum - - - - - Evolution of Medicine™ Mission Partners: TrueNeura: https://truneura.com/trunuera Fullscript Journeys: https://fullscript.com/lp/journeys-james-maskell Big Boost Marketing: https://goevomed.com/bigboost Freedom Practice Training: https://goevomed.com/fpc Genova Diagnostics: https://goevomed.com/genova - - - - - This podcast is produced by DrTalks.com https://drtalks.com/podcast-service/

  2. Sep 7 ·  Video

    The Neuroscience of Awakening

    In this episode, host James Maskell sits down with Dr. Helen Lavretsky — integrative and geriatric psychiatrist, neuroscientist, and professor of psychiatry at UCLA, where she directs clinical research on integrated mental health and serves as research director for UCLA's Integrative Medicine Collaborative. Her path into the field began through Kundalini Yoga, sparking 20 years of studying mind-body practices with rigorous neuroscience. Despite initial pushback in academic psychiatry, her evidence ultimately gained widespread acceptance. She details her clinical model: a partnership where patients choose self-regulation tools based on joy, avoiding rigid regimens. She also shares her landmark Kirtan Kriya research, showing that just 12 minutes of daily chanting meditation over 8 weeks rewired the brain, improved cognition, and reversed aging markers in dementia caregivers. Discussing her new book, Living from the Soul: The Neuroscience of Spiritual Awakening, she addresses patients experiencing "spiritual emergence"—symptoms like insomnia and body pain often misdiagnosed as psychiatric illness. She links these rising rates to global instability and generational shifts in resilience. They also explore brain health policy and the "Brain Capital" movement—from UCLA summits and UN testimonies to Texas's $3 billion Brain Health Institute. Finally, they examine environmental risk factors, genetic predispositions like APOE4, and offer a candid critique of long-term SSRI use in older adults. The episode closes on the future of precision medicine and data-driven Alzheimer's care. - - - - - About the Guest: Dr. Helen Lavretsky is an integrative and geriatric psychiatrist, neuroscientist, and professor of psychiatry at UCLA. She directs clinical research programs on integrated mental health and serves as director of research for the UCLA Integrative Medicine Collaborative. She is a past president of the American Association for Geriatric Psychiatry and the author of several books, including her latest, Living from the Soul: The Neuroscience of Spiritual Awakening. - - - - - Social Handles: Website: https://www.jamesmaskell.com/ X: https://x.com/mrjamesmaskell Instagram: https://www.instagram.com/mrjamesmaskell Facebook: https://www.facebook.com/jamesedwardmaskell/ Linkedin: https://www.linkedin.com/in/jamesmaskell Youtube: https://www.youtube.com/FunctionalForum - - - - - Evolution of Medicine™ Mission Partners: TrueNeura: https://truneura.com/trunuera Fullscript Journeys: https://fullscript.com/lp/journeys-james-maskell Big Boost Marketing: https://goevomed.com/bigboost Freedom Practice Training: https://goevomed.com/fpc Genova Diagnostics: https://goevomed.com/genova - - - - - This podcast is produced by DrTalks.com https://drtalks.com/podcast-service/

  3. Aug 31 ·  Video

    The Forgotten Medicine: Community, Dance & Song

    In this live episode from the Institute for Functional Medicine's Annual International Conference, host James Maskell sits down with Dr. Geeta Maker-Clark, who opened the conference that morning with its keynote address. The conversation begins with something unusual: conference attendees — mostly, as Maskell puts it, "type A, cerebral" doctors — got up and danced during her talk, a rare sight at a medical conference. Dr. Maker-Clark, who is part of a West African dance company, explains why: drumming and dance tap into something deeply primal in all of us, tied to ancestral rhythm, grief, celebration, and rites of passage — connections she says were severed largely through colonization. Maskell shares a parallel experience with communal singing, discovered through his men's group, and the two agree it produces a similarly embodied, collective effect. From there, the discussion turns to rebuilding what's been lost. Maskell describes creating a small home-school and community pod for his daughter, built around Dunbar's number, as a deliberate act of "rebuilding the tapestry" of connection. Dr. Maker-Clark reframes this broader work not as innovation but as remembrance and reclamation — recovering what our cells already know how to do. The conversation closes on health equity and food. Dr. Maker-Clark discusses her decade running a culinary medicine program at the University of Chicago Medical School, training physicians to talk with patients about food and cultural humility — a model that has now expanded to over 80 academic medical centers nationally. She and Maskell discuss group-based, cohort models of care as a scalable way to deliver this kind of medicine beyond wealthy populations, pushing back on the idea that holistic care is "just for rich people." The episode ends on a note about hope as a muscle — something we have to keep using. - - - - - About the Guest: Dr. Geeta Maker-Clark delivered the opening keynote at the Institute for Functional Medicine's Annual International Conference. She is a member of a West African dance company and runs the culinary medicine program at the University of Chicago Medical School, training physicians and medical students in nutritional science and cultural humility in patient care — a model now adopted across 80+ academic medical centers nationally. She has a book coming out later this summer. - - - - - Social Handles: Website: https://www.jamesmaskell.com/ X: https://x.com/mrjamesmaskell Instagram: https://www.instagram.com/mrjamesmaskell Facebook: https://www.facebook.com/jamesedwardmaskell/ Linkedin: https://www.linkedin.com/in/jamesmaskell Youtube: https://www.youtube.com/FunctionalForum - - - - - Evolution of Medicine™ Mission Partners: TrueNeura: https://truneura.com/trunuera Fullscript Journeys: https://fullscript.com/lp/journeys-james-maskell Big Boost Marketing: https://goevomed.com/bigboost Freedom Practice Training: https://goevomed.com/fpc Genova Diagnostics: https://goevomed.com/genova - - - - - PODCAST Thank you for listening. Please subscribe and share. This podcast is produced by DrTalks.com https://drtalks.com/podcast-service/

  4. Aug 24 ·  Video

    2026 Pauling Award Winner Reveals the Truth About Hormones & GLP-1s

    What does it take to earn functional medicine's highest honor? In this live episode from the Institute for Functional Medicine's 33rd Annual International Conference, host James Maskell sits down with Joel Evans, MD, FMCP-M, recipient of the 2026 Linus and Ava Helen Pauling Award in Functional Medicine — awarded to Joel Evans, MD, FMCP-M in recognition of his career-long contributions to the field. Joel Evans, MD, FMCP-M shares the story of his journey from OB-GYN to functional medicine leader, crediting Jeff Bland and Bethany Hayes for pulling him into the field early on. He discusses why women's health has reached a tipping point — driven by demographic shifts in menopause and perimenopause and the fading of old prohibitions against hormone therapy — and why he's concerned about the wave of unvetted hormone-health advice flooding social media. Joel Evans, MD, FMCP-M also breaks down the three hottest areas in women's health right now: metabolic flexibility, mitochondrial health, and the judicious use of GLP-1s, plus a cutting-edge use of FSH testing to fine-tune hormone dosing. Whether you're a practitioner, patient, or simply curious about where women's health is headed, this episode offers a firsthand look at the wisdom behind this year's Pauling Award win. - - - - - About the Guest: Joel Evans, MD, FMCP-M is the recipient of the 2026 Linus and Ava Helen Pauling Award in Functional Medicine, awarded at The Institute for Functional Medicine's 33rd Annual International Conference. Joel Evans, MD, FMCP-M is an OB-GYN and longtime leader in functional medicine's approach to women's health, having served on the scientific advisory board of Metagenics and led hormone health education for IFM. - - - - - Social Handles: Website: https://www.jamesmaskell.com/ X: https://x.com/mrjamesmaskell Instagram: https://www.instagram.com/mrjamesmaskell Facebook: https://www.facebook.com/jamesedwardmaskell/ Linkedin: https://www.linkedin.com/in/jamesmaskell Youtube: https://www.youtube.com/FunctionalForum - - - - - Evolution of Medicine™ Mission Partners: TrueNeura: https://truneura.com/trunuera Fullscript Journeys: https://fullscript.com/lp/journeys-james-maskell Big Boost Marketing: https://goevomed.com/bigboost Freedom Practice Training: https://goevomed.com/fpc Genova Diagnostics: https://goevomed.com/genova - - - - - PODCAST Thank you for listening. Please subscribe and share. This podcast is produced by DrTalks.com https://drtalks.com/podcast-service/

  5. Aug 17 ·  Video

    The Blueprint for Functional Medicine in Big Health Systems

    What does it actually take to build a functional medicine program that thrives inside a conventional health system? In this live episode from the Institute for Functional Medicine Annual Conference, James Maskell sits down with Laura Sandquist and Kate Otremba, who've spent six years building a large integrative and functional medicine program within Allina Health, a conventional health system in Minnesota. Laura and Kate share the infrastructure they built to make it work — smart phrases, practice guidelines, and templates that help clinicians translate their functional medicine training into daily practice within the constraints of RVU requirements and insurance billing. They discuss how they addressed access issues through nutritionist-led and practitioner/nutritionist co-led group medical visits, and how a two-day CME training for primary care providers and specialists helped build trust and drive more referrals and holistic thinking across the system. The conversation also covers their new venture, Whole Health NP, launched to help other practitioners bridge the gap between learning functional medicine and actually applying it — and why this whole-health approach extends well beyond integrative nursing to physical therapists, psychologists, and beyond. Whether you're a clinician, health system leader, or someone building functional medicine programs of your own, this episode offers a grounded, practical look at what it really takes to make whole health work at scale. - - - - - About the Guest: Laura Sandquist, DNP, APRN, A-GNP-C, FMCP-M and Kate Otremba, DNP, MN, APRN, CNP, FMCP-M are co-developers of a large integrative and functional medicine program within Allina Health, a conventional health system in Minnesota, where they have worked together for six years. Their work includes building clinical infrastructure such as smart phrases and practice guidelines, launching nutritionist-led and co-led group medical visits, and developing a two-day CME training for primary care providers and specialists to build trust and collaboration across the system. They have since launched Whole Health NP, a company dedicated to teaching practitioners how to translate functional medicine training into real-world practice. - - - - - Social Handles: Website: https://www.jamesmaskell.com/ X: https://x.com/mrjamesmaskell Instagram: https://www.instagram.com/mrjamesmaskell Facebook: https://www.facebook.com/jamesedwardmaskell/ Linkedin: https://www.linkedin.com/in/jamesmaskell Youtube: https://www.youtube.com/FunctionalForum - - - - - Evolution of Medicine™ Mission Partners: TrueNeura: https://truneura.com/trunuera Fullscript Journeys: https://fullscript.com/lp/journeys-james-maskell Big Boost Marketing: https://goevomed.com/bigboost Freedom Practice Training: https://goevomed.com/fpc Genova Diagnostics: https://goevomed.com/genova - - - - - PODCAST Thank you for listening. Please subscribe and share. This podcast is produced by DrTalks.com https://drtalks.com/podcast-service/

  6. Aug 10 ·  Video

    The Bioage Reversal Breakthrough

    What if the best way to live a long life isn't a longevity hack — but preventing chronic illness in the first place? In this live episode from the Institute for Functional Medicine Annual Conference, James Maskell sits down with Dr. Kara Fitzgerald, a naturopathic physician and longtime functional medicine researcher, to talk about her groundbreaking work on reversing biological age. Dr. Fitzgerald shares the story behind her 2018 clinical study, which found that a diet and lifestyle intervention reversed biological age by over three years — a result that stunned the field, since even epigenetic clock pioneer Steve Horvath didn't believe bioage reversal was possible in humans. She explains how follow-up research traced most of that effect to polyphenol-dense "methylation adaptogens," and why she's now pursuing an NIH grant to understand whether polyphenols can move the needle on both exposomic aging (environmentally driven) and deeper, programmed aging (the kind tied to Yamanaka factor biology). The conversation also covers the longevity summit she hosted last year to unite the functional and longevity medicine communities, her advice for practitioners building a career in this space — community, clarity of purpose, and in-person connection — and her take on where direct-to-consumer lab testing and wearables fit into the future of patient care. Whether you're a clinician, researcher, or simply curious about the science of aging, this episode offers a grounded look at what it actually takes to move the needle on healthspan and lifespan. - - - - - About the Guest: Dr. Kara Fitzgerald is actively engaged in clinical research on epigenetics and longevity using a diet and lifestyle intervention developed in her research and practice. She has published two clinical studies on the potential bioage-reversing effects of an 8-week DNA methylation-supportive diet and lifestyle in middle-aged men and women in the journal Aging. - - - - - Social Handles: Website: https://www.jamesmaskell.com/ X: https://x.com/mrjamesmaskell Instagram: https://www.instagram.com/mrjamesmaskell Facebook: https://www.facebook.com/jamesedwardmaskell/ Linkedin: https://www.linkedin.com/in/jamesmaskell Youtube: https://www.youtube.com/FunctionalForum - - - - - Evolution of Medicine™ Mission Partners: TrueNeura: https://truneura.com/trunuera Fullscript Journeys: https://fullscript.com/lp/journeys-james-maskell Big Boost Marketing: https://goevomed.com/bigboost Freedom Practice Training: https://goevomed.com/fpc Genova Diagnostics: https://goevomed.com/genova - - - - - PODCAST Thank you for listening. Please subscribe and share. This podcast is produced by DrTalks.com https://drtalks.com/podcast-service/

  7. Aug 3 ·  Video

    Why Whole Health Starts With This One Question

    What does it really mean to practice "whole health" — and how do we keep it from becoming just another buzzword? In this live episode from the Institute for Functional Medicine Annual Conference, James Maskell sits down with Dr. Tracy Gaudet to unpack the evolution of whole health, the growing risk of paradigm "veneers" masking real transformation, and why the patient-practitioner relationship remains central to any lasting healing. Tracy explains how true system change begins with a different kind of conversation — one that starts with a person's purpose and meaning rather than their diagnosis — and why that shift produced measurable clinical improvements in her work with the VA. She and James also discuss the rising infighting among healthcare "tribes" (functional, integrative, lifestyle medicine) and the opportunity to synergize instead of stake out territory from a place of fear and scarcity. The conversation turns to promising green shoots of change: land-grant universities like Virginia Tech stepping into community health leadership, and the first-of-its-kind Doctorate in Whole Health Leadership at Southern California University of Health Sciences (SCU), which Tracy helped design and James is now personally joining. Whether you're a clinician, health system leader, or an aspiring agent of change, this episode offers a grounded, honest look at what it will really take to humanize modern medicine. - - - - - About the Guest: Dr. Tracy Gaudet is a physician and national leader in whole health transformation, best known for spearheading the U.S. Department of Veterans Affairs' Whole Health System — one of the largest whole-person healthcare transformation efforts in the country. She helped design and now teaches in the first Doctorate in Whole Health Leadership program at Southern California University of Health Sciences (SCU), training clinicians, administrators, and educators to lead system-wide transformation toward humanized, whole-person care. Tracy's work centers on shifting healthcare conversations from disease and diagnosis to purpose and meaning as the true foundation of lasting behavior change. - - - - - Social Handles: Website: https://www.jamesmaskell.com/ X: https://x.com/mrjamesmaskell Instagram: https://www.instagram.com/mrjamesmaskell Facebook: https://www.facebook.com/jamesedwardmaskell/ Linkedin: https://www.linkedin.com/in/jamesmaskell Youtube: https://www.youtube.com/FunctionalForum - - - - - Evolution of Medicine™ Mission Partners: TrueNeura: https://truneura.com/trunuera Fullscript Journeys: https://fullscript.com/lp/journeys-james-maskell Big Boost Marketing: https://goevomed.com/bigboost Freedom Practice Training: https://goevomed.com/fpc Genova Diagnostics: https://goevomed.com/genova - - - - - PODCAST Thank you for listening. Please subscribe and share. This podcast is produced by DrTalks.com https://drtalks.com/podcast-service/

  8. Jul 27

    Inside the Growth of Functional Medicine

    How is functional medicine evolving from a niche practice into a global movement that is transforming healthcare? In this live episode from the Institute for Functional Medicine Annual Conference, James Maskell sits down with Amy R. Mack, MSES, MPA, CEO of the Institute for Functional Medicine (IFM), to discuss the organization's mission, the rapid growth of functional medicine, and its future in healthcare. Amy shares how her background in nonprofit leadership—and the influence of her father, a gastroenterologist who practiced whole-person care long before it became mainstream—shaped her passion for expanding access to functional medicine. The conversation explores IFM's evolution toward making functional medicine available to more patients by educating practitioners across more than 20 healthcare professions and supporting its integration into hospitals, universities, and large healthcare systems. Amy explains why standardized certification, practitioner competencies, and collaboration across organizations are essential for maintaining quality as the field grows. James and Amy also discuss the importance of building stronger scientific evidence through functional medicine research, including emerging work on chronic disease and cognitive decline. They examine how artificial intelligence is improving public awareness of functional medicine and helping provide more accurate information than outdated online sources. Finally, they explore the growing international adoption of functional medicine, emphasizing the importance of adapting its principles to different cultures while fostering global collaboration and innovation. Whether you're a healthcare professional, health leader, or someone interested in personalized, root-cause medicine, this episode offers valuable insights into the future of functional medicine and the movement to make whole-person healthcare more accessible worldwide. - - - - - About the Guest: Amy R. Mack, MSES, MPA, is the Chief Executive Officer of the Institute for Functional Medicine (IFM). With a background in nonprofit leadership, public service, and organizational development, she has led IFM's mission to expand access to functional medicine through practitioner education, research, certification, and healthcare collaboration. Under her leadership, IFM has trained more than 100,000 healthcare professionals worldwide while advancing the integration of functional medicine into hospitals, academic institutions, and healthcare systems. Amy is passionate about making root-cause, patient-centered healthcare more accessible while maintaining rigorous education and clinical standards. - - - - - Social Handles: Website: https://www.jamesmaskell.com/ X: https://x.com/mrjamesmaskell Instagram: https://www.instagram.com/mrjamesmaskell Facebook: https://www.facebook.com/jamesedwardmaskell/ Linkedin: https://www.linkedin.com/in/jamesmaskell Youtube: https://www.youtube.com/FunctionalForum - - - - - Evolution of Medicine™ Mission Partners: TrueNeura: https://truneura.com/trunuera Fullscript Journeys: https://fullscript.com/lp/journeys-james-maskell Big Boost Marketing: https://goevomed.com/bigboost Freedom Practice Training: https://goevomed.com/fpc Genova Diagnostics: https://goevomed.com/genova - - - - - PODCAST Thank you for listening. Please subscribe and share. This podcast is produced by DrTalks.com https://drtalks.com/podcast-service/

See All (100)

4.8
out of 5
98 Ratings

About

Hear from the experts that are driving the evolution of medicine.

Information

You Might Also Like