The Human 5.0 Project

Ultimate Biohacker 10x
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The Human 5.0 Project is the podcast where science meets self-optimization. Hosted by Ultimate Biohacker 10X, this show explores the real research, real data, and real dosing behind today’s most effective biohacking tools — from peptides, longevity molecules, and nootropics to recovery devices, lifestyle strategies, sleep optimization, training principles, and cutting-edge performance tech. Each episode breaks down complex biology into practical, actionable protocols you can use to improve energy, metabolism, cognition, and overall healthspan. No hype. No fluff. Just evidence-based insights for people who want to understand their bodies, upgrade their biology, and unlock their highest potential. If you’re ready to optimize your life one pathway at a time, you’re in the right place.

  1. HACE 4 H

    How to Test Your True Biological Age in 2026 – Epigenetic Clocks, Telomeres & Results Explained

    Biological Age vs Chronological Age: The Real Tests That Tell You How Old You Actually Are   Ever wonder why two people the same age feel completely different? Your driver’s license is just a number—your cells have their own clock. In this episode, we break down chronological, genetic (intrinsic), and biological age, plus the top tests that reveal how fast you’re actually aging: telomere length, epigenetic clocks (Horvath, GrimAge, PhenoAge, DunedinPACE), TruDiagnostic, Elysium, GlycanAge, and more. We cover:   How telomere shortening and DNA methylation drive aging At-home testing: spit, finger prick, blood spot—what to expect What your results mean (and the limitations) Why these tests are game-changers for longevity, healthspan, and motivation     Intro: Your body’s real age The three ages explained Telomeres, methylation & epigenetics The tests: which ones actually work Interpreting results & red flags Why you should care (and what to change) Final thoughts & action plan If you’ve run a biological age test, drop your results in the comments—what did it say, and what did you do about it? Subscribe for more cutting-edge biohacking, longevity science, and optimization protocols. Hit the bell so you never miss an update.   🔥 Subscribe for no-BS biohacking & longevity drops Follow on IG @Ultimatebiohacker10X For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies. And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.   #BiologicalAge #EpigeneticClock #AgingScience #ReverseAging #Telomeres #DNAMethylation #Longevity #Biohacking #Human5.0 #TruDiagnostic #GrimAge #DunedinPACE #HealthOptimization #AntiAging #Biohacker

    10 min

  2. HACE 23 H

    AMPK Activation Explained: Exercise + Fasting + mTOR Balance (2026 Guide)

    Stop Chasing Hacks: AMPK + mTOR + Fasting + Exercise Cold plunges are the headline… but AMPK is the real story. In this episode, UltimateBiohacker10X breaks down AMPK (your cell’s low-energy switch) in plain English, then shows how to activate it without living in an ice bath—using exercise, fasting/low glycogen, and recovery strategy.   We also add the missing piece most people ignore: mTOR—the “build mode” signal. The goal isn’t “AMPK forever” or “mTOR forever.” The goal is cycling stress → recovery → adaptation so you don’t become a metabolic hostage.   No hype. Just mechanisms + measurement, plus a clean 30-day framework so you can run one lane, track outcomes, and stop stacking chaos.   What you’ll learn:   What AMPK actually does (fuel use + efficiency mode)   Why exercise is the king AMPK trigger   How fasting can help (and how people misuse it)   AMPK vs mTOR: efficiency mode vs build mode (why balance = longevity)   Red flags you’re overdrafting recovery   A simple 30-day experiment framework (goal → baseline → measure → stop rule)       Open — Cold isn’t the point Disclaimer + rules (foundations first) AMPK explained like you’re human (low-battery mode) Myth buster — more AMPK isn’t always better Activator #1: Exercise (the cleanest AMPK trigger) Activator #2: Fasting / low glycogen (powerful, easy to misuse) AMPK vs mTOR (growth mode vs efficiency mode) “Beyond basics” — research tools vs real life (don’t stack chaos) Safety + red flags (overdrafting recovery) 30-day “run it clean” framework Close — cycle stress + recovery, measure everything   🔥 Subscribe for no-BS biohacking & longevity drops Follow on IG @Ultimatebiohacker10X For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies. And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications. #AMPK #mTOR #Fasting #IntermittentFasting #ExerciseScience #Zone2 #HIIT #MetabolicHealth #FatOxidation #Mitochondria #Longevity #Autophagy #InsulinSensitivity #Biohacking #HealthOptimization #UltimateBiohacker10X #Recovery #StrengthTraining #MetabolicFlexibility #ColdExposure

    12 min

  3. HACE 1 DÍA

    Cold Plunge Science 2026: AMPK, Brown Fat, Mitochondria & What Actually Changes

    AMPK Explained Simply: How Cold Exposure Triggers Fat Burning, Glucose Uptake & “Cell Cleanup”   Cold exposure isn’t a masculinity contest — it’s a stimulus. And the real story is what happens inside your cells when energy demand spikes.   In this episode, UltimateBiohacker10X breaks down AMPK (5' AMP-activated protein kinase) in plain English: your body’s internal “low fuel” switch that shifts you from storage/build mode into use/repair mode. We connect AMPK to cold thermogenesis, brown fat (BAT), mitochondrial signaling, and give you safe, repeatable protocols (cold showers → cold walks → cold plunge) without the ego traps.   No hype. Just signal: how to use cold as an amplifier, what outcomes are realistic, and what to track so you don’t confuse vibes with results.   NOT medical advice. If you have heart rhythm issues, Raynaud’s, cold urticaria, fainting history, pregnancy, or uncontrolled BP—talk to a clinician and don’t do cold water exposure alone.   If you want Part 2: “AMPK Activators Beyond Cold (exercise, fasting, sleep)” comment AMPK2.   🔥 Subscribe for no-BS biohacking & longevity drops Follow on IG @Ultimatebiohacker10X For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies. And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.   Cold isn’t the point (open) Disclaimer + safety rules (don’t be a hero) AMPK explained like you’re human (fuel gauge / low power mode) What actually flips AMPK on (energy demand triggers) AMPK downstream effects (fuel partitioning + repair/efficiency) Cold thermogenesis: what it is vs. what it isn’t Brown fat (BAT) + why results vary person-to-person Practical protocols (cold shower → cold walk → cold plunge) How to measure results + stop rules (adult framework) Close + next episode teaser   #AMPK #ColdThermogenesis #ColdExposure #IceBath #ColdPlunge #Biohacking #MetabolicHealth #FatLossScience #MetabolicFlexibility #BrownFat #Mitochondria #GlucoseControl #Autophagy #Recovery #PerformanceHealth #UltimateBiohacker10X #NoHype #HealthOptimization #WellnessScience #2026Biohacking#TheHuman5.0Project

    14 min

  4. HACE 2 DÍAS

    Peptides 2026: Evidence Ladder + Quality Red Flags (Don’t Get Played)Part2

    Peptides Masterclass Part 2: Evidence Tiers + Purity Red Flags (No Hype) People love peptide “stacks.” Reality loves baselines, evidence tiers, and stop rules.   Part 1(click here)   In Part 2 of the Peptides Masterclass, UltimateBiohacker10X breaks down the Evidence Ladder (Tier 1 human RCTs → Tier 2 small human/mechanistic → Tier 3 preclinical/early) and the Quality Red Flags that turn “biohacking” into expensive confusion.   We run the 5 peptide buckets people actually search:   Fat loss: GLP-1 context + AOD-9604 reality check Injury/Recovery: BPC-157 + TB-500 (what we know vs what’s assumed) Sleep/Brain: Selank, Semax, DSIP (mechanism ≠ outcome) Longevity/Immune: TA1, MOTS-c, KPV (define longevity with metrics) Skin/Hair: GHK-Cu + topical penetration reality (physics > marketing)   Rule #1 stays undefeated: foundations first. If you aren’t tracking baselines, you aren’t doing an experiment—you’re doing a vibe. Educational only. Not medical advice. No dosing. No sourcing. Consult a qualified clinician for personalized decisions.     🔥 Subscribe for no-BS biohacking & longevity drops Follow on IG @Ultimatebiohacker10X For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies. And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.   Open — Evidence Ladder + “Don’t get played” Evidence Ladder explained (Tier 1 / 2 / 3) Bucket 1 — Fat loss (GLP-1s + AOD-9604 evidence + red flags) Bucket 2 — Injury/Recovery (BPC-157 + TB-500 reality check) Bucket 3 — Sleep/Brain (Selank, Semax, DSIP: what’s real vs wanted) Bucket 4 — Longevity/Immune (TA1, MOTS-c, KPV: evidence ladder) Bucket 5 — Skin/Hair (GHK-Cu + topical penetration reality) Universal Quality Red Flags (purity, stacking, no baseline) Close — pick one lane, measure, stop rules       #Peptides #Biohacking #Longevity #HealthOptimization #NoHype #EvidenceBased #Wellness #Recovery #SleepHacks #FatLoss #GLP1 #BPC157 #TB500 #Semax #Selank #DSIP #MOTSc #ThymosinAlpha1 #GHKCu #SkincareScience #AntiAging #FitnessScience #UltimateBiohacker10X #HumanPerformance #2026#TheHuman5.0Project

    11 min

  5. HACE 2 DÍAS

    Peptides in 2026: 5 Reasons People Use Them + A No-Hype Framework (Fat Loss, Recovery, Sleep, Longevity)

    Peptides Masterclass (2026): The 5 Buckets + How to Run a Clean Experiment Peptides are trending in 2026 for five reasons: fat loss, injury recovery, sleep/brain performance, longevity/inflammation, and skin/hair. In this no-hype masterclass, UltimateBiohacker10X breaks down what each bucket is trying to do, where evidence is stronger vs thinner, and the adult decision framework that keeps you from getting played:   ✅ Foundations first ✅ Goal → baseline → measure → stop rule ✅ One lane at a time (no stacking chaos) ✅ Track outcomes, not vibes   Comment “PEPTIDES2” if you want Part 2: Evidence Ladder + Quality Red Flags.   DOWNLOAD: Peptide Dosing Guide DOWNLOAD: Outline For The Episode/Peptide Masterclass (and how to follow it cohesively)   Open — 5 reasons people search peptides Ground rules + disclaimer Rule #1 — foundations first Bucket 1 — fat loss (context + measurement) Bucket 2 — injury/recovery (reality check + rehab first) Bucket 3 — sleep/brain (hierarchy + tracking) Bucket 4 — longevity/inflammation (scorecard thinking) Bucket 5 — skin/hair (topical reality + SPF) Decision framework (goal → baseline → measure → stop rule) Peptides and when to use them Close 🔥 Subscribe for no-BS biohacking & longevity drops Follow on IG @Ultimatebiohacker10X For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies. And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.     #Peptides #Biohacking #Longevity #FatLoss #Recovery #SleepOptimization #HRV #BodyComposition #AntiAging #UltimateBiohacker10X #Healthspan #FitnessScience#TheHuman5.0Project

    16 min

  6. HACE 3 DÍAS

    VIP Peptide 2026: What It Really Does for Inflammation, Gut Health & Anti-Aging (No Hype Guide)

    In this 30-minute masterclass, UltimateBiohacker10X breaks down VIP (Vasoactive Intestinal Peptide): endogenous vs. aviptadil, mechanisms (vasodilation, anti-inflammatory), evidence from RCTs (COVID/ARDS trials), benefits (respiratory, neuroprotection, skincare), safety (BP drops, GI effects), and a no-BS decision framework. Plus: quality warnings and better alternatives like sleep/conditioning. No fluff—just signal for biohackers chasing real outcomes.   Open Ground Rules VIP 101 Mechanism VIP vs Aviptadil Plausible Uses Safety Decision Framework Don’t Get Played Alternatives Close Comment: What's your top inflammation hack? #VIPPeptide   🔥 Subscribe for no-BS biohacking & longevity drops Follow on IG @Ultimatebiohacker10X For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies. And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications. #VIPPeptide #Biohacking #AntiInflammatory #GutHealth #AntiAging #Neuroprotection #Peptides #Longevity #InflammationHacks #UltimateBiohacker10X #Health#TheHuman5.0Project

    10 min

  7. HACE 3 DÍAS

    Skin Anatomy & Absorption Explained: How Peptides Work in Skincare + Top Tips for Beginners (2026 Guide)

    Don't Get Played By Marketing...    In this 20-minute masterclass, we break down skin anatomy (epidermis, dermis, hypodermis), how ingredients actually penetrate the barrier (intercellular, transcellular, transfollicular routes + 500 Dalton rule), and why peptides like Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, and Decapeptide-52 are game-changers for anti-aging, firmness, and glow. We cover TEWL, stratum corneum, hydrolipidic film, diet tips (vitamin C, omega-3s, zinc), and procedures like microneedling/PRP. No fluff—just science-backed strategies to upgrade your routine.   Intro Disclaimer & Frame The Three Layers of Skin Stratum Corneum & Hydrolipidic Film Penetration vs Absorption The Three Entry Routes 500 Dalton Rule Step-by-Step Permeation Factors Controlling Absorption Practical Protocols Transition to Peptides Close & Sign-Off IF YOU WANT TO BE ONE OF THE FIRST TO TRY OUR NEW LINE: CoDermaSkincare.com   🔥 Subscribe for no-BS biohacking & longevity drops Follow on IG @Ultimatebiohacker10X For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies. And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.   #SkincareScience#SkinAnatomy #SkincareAbsorption #PeptidesInSkincare #AntiAgingSkincare #SkinBarrier #TEWL #Dermis #Epidermis #Hypodermis #Microneedling #PRP #SkincareTips #Biohacking #UltimateBiohacker10X #BeautyScience2026#Human5.0Project#CoDerma#Codermaskincare

    16 min

  8. HACE 5 DÍAS

    Recurrent Laryngeal Nerve (RLN) Paralysis: Best Treatments After Surgery (Voice, Swallow, Recovery)

    f you’re dealing with recurrent laryngeal nerve (RLN) paralysis after surgery (including traction-related injury), this episode breaks down what actually helps—from first-line voice therapy to procedures like injection laryngoplasty and medialization thyroplasty, plus reinnervation options and what’s emerging next. UltimateBiohacker10X style: straight facts, zero filler, practical decision-making. Key disclaimer: Educational information only — not medical advice. RLN paralysis can cause hoarseness, swallowing issues (dysphagia/aspiration), or breathing problems. See an ENT/laryngologist for evaluation (often with laryngoscopy and sometimes stroboscopy). Treatment depends on whether paralysis is unilateral vs bilateral, severity, and how long it’s been present. What you’ll learn in this episode How RLN paralysis happens (especially traction injuries) and what recovery timelines look like First-line rehab: voice therapy + swallow therapy (what’s typically trained and why it works) Adjunct options: manual/myofascial work, home practice, and where e-stim may fit Procedure lane (3–6+ months or significant symptoms): Injection laryngoplasty (temporary but often fast symptom relief) Medialization thyroplasty ± arytenoid adduction (durable mechanical fix) Selective laryngeal reinnervation (restoring tone/positioning over time) Bilateral paralysis considerations: airway first; pacing/implants are emerging Nutrients & supplements for nerve support (adjunctive, not magic) Cutting-edge/experimental territory: what’s plausible, what’s hype, and how to think like a clinician Quick listener action plan Confirm diagnosis + laterality with an ENT/laryngologist Start SLP-led voice/swallow therapy early If symptoms are limiting function, ask about early injection laryngoplasty Reassess at 3–6 months for longer-term procedural options if needed Support the biology: sleep, protein, micronutrient sufficiency, inflammation control 🔥 Subscribe for no-BS biohacking & longevity drops Follow on IG @Ultimatebiohacker10X For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies. And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.   #RecurrentLaryngealNerve #RLN #VocalCordParalysis #VocalFoldParalysis #VoiceTherapy #SpeechTherapy #SwallowTherapy #Dysphagia #Hoarseness #Laryngology #ENT #InjectionLaryngoplasty #MedializationThyroplasty #LaryngealReinnervation #AnsaCervicalis #VoiceRehab #AirwayProtection #PostSurgeryRecovery #NerveInjury #PeripheralNerveRepair #Neurorehab #Biohacking #HealthOptimization #Longevity #EvidenceBased #UltimateBiohacker10X #TheHuman5Project

    13 min
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The Human 5.0 Project is the podcast where science meets self-optimization. Hosted by Ultimate Biohacker 10X, this show explores the real research, real data, and real dosing behind today’s most effective biohacking tools — from peptides, longevity molecules, and nootropics to recovery devices, lifestyle strategies, sleep optimization, training principles, and cutting-edge performance tech. Each episode breaks down complex biology into practical, actionable protocols you can use to improve energy, metabolism, cognition, and overall healthspan. No hype. No fluff. Just evidence-based insights for people who want to understand their bodies, upgrade their biology, and unlock their highest potential. If you’re ready to optimize your life one pathway at a time, you’re in the right place.

Información

  • Creador
    Ultimate Biohacker 10x
  • Años de actividad
    2025 - 2026
  • Episodios
    98
  • Clasificación
    Apto
  • Copyright
    © Copyright 2025 All rights reserved.
  • Mostrar sitio web
    The Human 5.0 Project

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