The Pulse

WHYY

Go on an adventure into unexpected corners of the health and science world each week with award-winning host Maiken Scott. The Pulse takes you behind the doors of operating rooms, into the lab with some of the world's foremost scientists, and back in time to explore life-changing innovations. The Pulse delivers stories in ways that matter to you, and answers questions you never knew you had.

  1. From Buzz to Burnout: How Alcohol Affects the Brain and Body

    41 min ago

    From Buzz to Burnout: How Alcohol Affects the Brain and Body

    At the best of times, alcohol makes us feel great — relaxed and gregarious, warm and fuzzy, happy and confident. But at the worst of times, it can morph into a serious problem, damaging our relationships, our health, and our lives as a whole. On this encore episode, we explore our relationship with alcohol. Why we consume it, how it affects us, and when it’s time to quit. We talk with surgeon and recovering alcoholic Charles Knowles about how booze affects our brains and health, and what finally pushed him to give up alcohol for good; we hear about a trend known as “California sober,” and why so many people are embracing it; and we find out how zero-proof cocktail bars are helping some people socialize without the booze. Charles Knowles was barely a teen when he discovered the power of alcohol to transform him from a shy outsider into the life of the party. But as he got older, and sank deeper into drinking, alcohol stopped being fun — and started affecting his health and his life. We talk with Knowles,  a surgeon and physician, about what makes some people more vulnerable to problematic drinking, how alcohol affects our brains, and how his life changed once he stopped drinking. Knowles’ book is “Why We Drink Too Much: The Impact of Alcohol on Our Bodies and Culture.” For a lot of former drinkers, “sobriety” means total abstinence — no alcohol, or any other substances that produce a similar buzz. But recently, a new, more permissive version of sobriety has been gaining popularity: “California sober.” It involves embracing cannabis and psychedelics as a means of avoiding alcohol and hard drugs. Reporter Andrew Stelzer tracks the origins of this phenomenon, why some people find it helpful, and what researchers have to say about it. One of the hardest parts about sobriety for a lot of people is dealing with the social impact. Not only is alcohol a social lubricant — it’s often at the center of social events themselves. But recently, some entrepreneurs have been creating alternatives in the form of zero-proof cocktail bars. Pulse reporter Alan Yu visits Philadelphia’s Bar Palmina to find out who goes there, and why.

    50 min
  2. How Science and Ingenuity Built Early America

    25 Jun

    How Science and Ingenuity Built Early America

    Two hundred and fifty years ago, Philadelphia was not just the center of political revolution, but a hub of scientific discovery. For America’s founders, science was more than a pastime — it was a way of understanding the world and the natural laws that shaped it. On this episode, we explore how science and innovation helped give birth to a new nation. We visit the American Philosophical Society in Philadelphia to explore how tracking the transit of Venus in 1769 became a major success for astronomers in the colonies, one that put American science on the map. We’ll also hear about efforts to find the exact location of the observatory that once stood near Independence Hall — the place some people say was the location where the Declaration of Independence was read out loud for the first time. The first sentence of the Declaration of Independence cites, “Laws of Nature and of Nature's God,” but what exactly does that mean? Caroline Winterer, Professor of History and American Studies at Stanford University joins us to discuss the ideas that allowed the Founders to bridge the gap between physical science and political governance, effectively inventing our modern concepts of society and inalienable rights. We dive into the story of the "Turtle," the first submarine used in combat which was invented during the Revolutionary War. Reporter Alan Yu explains the many innovations contained in this small vessel, and its daring first mission. Then Host Maiken Scott travels to The International Spy Museum in Washington, D.C., to see a replica of the craft. We head into the kitchen with three prominent Black Philadelphia chefs, Omar Tate, Angie Brown, and Shola Olunloyo, to reconstruct an iconic dish that fueled the revolution: Philadelphia pepper pot soup. Reporter Justin Kramon tells the story of this dish, and how people are keeping its memory alive.

    1hr 3min
  3. The Body Remembers: Exploring the Invisible Wounds Left by Serious Illness

    18 Jun

    The Body Remembers: Exploring the Invisible Wounds Left by Serious Illness

    On this episode, we explore the lingering effects of medical crises, both physical and emotional, and what true healing really means. We hear about one doctor’s journey to reconnecting with her body — and her pain — after nearly dying, what researchers are learning about medical trauma, and how a traumatic brain injury transformed the lives and marriage of a couple. As a physician, Rana Awdish’s goal was to get her patients healthy as quickly as possible. But when she  experienced her own medical emergency — one that ended her pregnancy and nearly killed her — her perspective on the role of clinicians shifted. Awdish later wrote a memoir about her experience, “In Shock,” that explored the importance of not only healing patients, but connecting with them on an emotional level. But the story didn’t end there. Fellow doctor and podcast host Neda Frayha talks with Awdish about her continuing journey, in the wake of the book’s success, to realizing that she hadn’t fully healed from her medical crisis, and that just as clinicians needed to connect with their patients, she needed to connect with her own body. Awdish’s new book is "After Shock: Learning to Reinhabit My Body After Illness." We talk with psychologist Jim Jackson about his decades-long work on medical trauma — the invisible psychological scars that many patients experience after serious illness or injuries. We hear about the causes of medical trauma, helpful and harmful ways of responding to it, and treatment options. His new book is “Reclaiming Your Life from Medical Trauma: Recognize the Symptoms, Find Treatment That Works, and Heal Your Brain and Body.” Medical crises don’t just affect patients — they affect their loved ones too. Pulse reporter Liz Tung talks with writer Abby Maslin and her husband T.C. Maslin about dealing with the fallout of an assault that almost killed T.C., and left him with a traumatic brain injury. They explore the effects on their lives and marriage — and dealing with cognitive and personality changes that made Abby feel like she was married to a stranger. Her book on their experience is “Love You Hard: A Memoir of Marriage, Brain Injury, and Reinventing Love.”

    50 min
  4. When Healthcare Meets the Law: Abortion, Cannabis, and Corporate Medicine

    4 Jun

    When Healthcare Meets the Law: Abortion, Cannabis, and Corporate Medicine

    On this episode, we look at the intersection of health, medicine, and the law. We explore how the upcoming rescheduling of marijuana may impact research on the drug, hear the story of a doctor who faced manslaughter charges in the 1970s for providing an abortion, and learn about legislation that some states are using to try and keep private equity out of medicine. Near the end of 2025, President Donald Trump made an announcement that marijuana advocates had been waiting decades to hear — plans by the federal government to move cannabis from schedule 1 to schedule 3, a much less restrictive legal category that would allow scientists to more easily conduct research on the drug’s therapeutic value. Pulse reporter Liz Tung digs into the history of how cannabis first became a federally illicit drug, what impact that status has had on research, and how much of a difference rescheduling will really make. We talk with Britt Carpenter, a recovery advocate and executive director of Philly Unknown Project, about how medical marijuana helped him get off opioids after years of addiction — and how the stigma against marijuana may prevent others from doing the same. Abortion has been in a state of legal flux ever since the U.S. Supreme Court overturned Roe v. Wade, putting many providers at risk of criminal prosecution. That might seem like a new development — but doctors faced similar pressures in the tumultuous years after Roe v. Wade was first decided. Reporter Linda Marsa tells the story of one young physician named Kenneth Edelin who became a national focal point of the debate after facing manslaughter charges for performing an abortion. It seems like a simple, common sense idea — that medical decisions should be made by doctors, not investors. But it’s an idea that’s been increasingly under threat, thanks to the rise of private equity in medicine. Now, some states are pushing back, with legislation aimed at curbing corporate influence in healthcare. Pulse reporter Alan Yu breaks down a recent court case out of Oregon that tested one such law, how it was decided, and what it could mean other states moving forward.

    50 min
  5. Engineering Happiness into Our Daily Lives

    28 May

    Engineering Happiness into Our Daily Lives

    Think about the last time you were really happy — where were you? What were you doing? Who were you with? And, most importantly, how can you recreate that feeling? Happiness can feel like lightning in a bottle — beautiful in the moment, but hard to find and harder yet to sustain. So what is it that makes for a happy life? And how do we engineer our lives for greater contentment, fulfillment, and joy? On this encore episode: the science of happiness and how we can experience more of it every day. We talk with psychologist Eric Zillmer about why certain places bring us joy, and how to engineer happiness in our lives. We hear about one reporter’s experiment to bring more moments of serendipity in her life. And, writer Daniel Coyle explains why community is at the heart of what it means to flourish. Drexel University psychologist Eric Zillmer created a “happiness map” of Philadelphia with the help of his students. He says it holds greater lessons on why certain places bring us joy, and how we can reverse-engineer happiness into our days. Zillmer directs the happiness lab at Drexel University. Writer Daniel Coyle built his career on exploring what it is that makes people successful — but when both of his parents died a few years ago, Coyle found himself unmoored, questioning what makes for a happy and meaningful life. The resulting journey led to his newest book, “Flourish: The Art of Building Meaning, Joy, and Fulfillment.” We talk with Coyle why he says community is at the heart of flourishing, how to create the right conditions for happiness, and why he says life isn’t a treasure hunt — it’s the process of treasure creation.

    50 min
  6. The Strange Science of Color — And Our Quest to Understand It

    21 May

    The Strange Science of Color — And Our Quest to Understand It

    On this episode, we explore the world of color — from how we perceive it, to our efforts to describe and differentiate its many shades. We talk with a lexicographer about efforts to standardize synthetic colors, and how we describe them, and investigate how we know that the colors we see are the same as the ones everyone else sees. The Pulse host Maiken Scott adds some pops of color to her all-black wardrobe with help from Jill Rafter, a color consultant with House of Colour, who breaks down seasonal palettes and how to choose your ideal hues based on your skin’s undertones. We talk with lexicographer Kory Stamper about her deep dive into the origins of ultra-specific color definitions, and the fascinating history of how major global changes, ranging from industrialization to international warfare, led to a government effort to standardize not just the production of synthetic colors, but also how we talk about them. Stamper’s new book is “True Color: The Strange and Spectacular Quest to Define Color – from Azure to Zinc Pink.” How do we know that the colors we see are the same as the colors other people see? Pulse reporter Liz Tung talks with University of Pennsylvania researcher David Brainard about the science of how we perceive color, what we know — and don’t know — about our shared perceptions, and the philosophical questions this raises about the nature of subjective experience. Pulse producer Nichole Currie talks with Cricket Matthews, who experiences  grapheme-colors synesthesia, a unique neurological trait in which letters, numbers, and words trigger specific colors in your mind.

    49 min

Hosts & Guests

About

Go on an adventure into unexpected corners of the health and science world each week with award-winning host Maiken Scott. The Pulse takes you behind the doors of operating rooms, into the lab with some of the world's foremost scientists, and back in time to explore life-changing innovations. The Pulse delivers stories in ways that matter to you, and answers questions you never knew you had.

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