19 episodes

Since coming on the market over a decade ago, e-cigarettes have divided opinion. A team of Oxford researchers are searching for new e-cigarette studies every month. In this podcast, Dr Jamie Hartmann-Boyce and Dr Nicola Lindson talk about what has been found, and how this changes what we know about e-cigarettes.
This podcast is made possible through funding from Cancer Research UK.
Art work by Olivia Barratier.
Produced by Dr Ailsa Butler.

Let's talk e-cigarettes Oxford University

    • Education
    • 5.0 • 3 Ratings

Since coming on the market over a decade ago, e-cigarettes have divided opinion. A team of Oxford researchers are searching for new e-cigarette studies every month. In this podcast, Dr Jamie Hartmann-Boyce and Dr Nicola Lindson talk about what has been found, and how this changes what we know about e-cigarettes.
This podcast is made possible through funding from Cancer Research UK.
Art work by Olivia Barratier.
Produced by Dr Ailsa Butler.

    September 2022 with Harry Tattan-Birch

    September 2022 with Harry Tattan-Birch

    Jamie Hartmann-Boyce and Nicola Lindson discuss emerging evidence in e-cigarette research and interview Harry Tattan-Birch. In the September episode Jamie Hartmann-Boyce interviews Harry Tattan-Birch from the Department of Behavioural Science and Health, University College London. Harry Tattan-Birch talks about their team's recent randomised controlled trial examining whether, in adults receiving behavioural support, offering e-cigarettes together with varenicline helps more people stop smoking cigarettes than varenicline alone. Tentative evidence suggests that offering e-cigarettes alongside varenicline to people receiving behavioural support may be more effective for smoking cessation than varenicline alone. https://doi.org/10.1093/ntr/ntac149 Harry Tattan-Birch also discusses his research into heated tobacco products.

    This work was funded by the Oxford University Public Policy Challenge Fund and Cancer Research UK.

    Jamie and Nicola also bring us up to date with the literature search conducted between July and September 1st 2022. The July, August and September searches found 6 new studies. We will include the studies we have found in future updates of the Cochrane review.

    For more information on the full Cochrane review updated in September 2021 see: https://doi.org/10.1002/14651858.CD010216.pub6 or our webpage: https://www.cebm.ox.ac.uk/research/electronic-cigarettes-for-smoking-cessation-cochrane-living-systematic-review-1

    • 23 min
    June 2022 with Dr Francesca Pesola

    June 2022 with Dr Francesca Pesola

    Jamie Hartmann-Boyce and Nicola Lindson discuss emerging evidence in e-cigarette research and interview Dr Francesca Pesola. In the June episode Jamie Hartmann-Boyce talks with Francesca Pesola from the Wolfson Institute of Population Health Queen Mary University of London. Dr Francesca Pesola talks to Associate Professor Jamie Hartmann-Boyce about the results from the trial comparing e-cigarettes to nicotine patches for smoking cessation in pregnant women. Professor Tim Coleman discussed this study in the May 2021 podcast and the results have now been published in Nature Medicine, Hajek et al 2022 (DOI: 10.1038/s41591-022-01808-0).
    Dr Pesola outlines the need to identify smoking cessation aids to help women quit during pregnancy. Dr Pesola discusses the results of their randomised control trial of 1,140 participants comparing refillable e-cigarettes with nicotine patches. In this trial pregnant women who smoke were randomized to e-cigarettes or nicotine patches. Dr Pesola reports that the unadjusted analysis of the primary outcome of validated quit rates at the end of pregnancy were not found to be significantly different between the e-cigarette and nicotine patch arms. However, Dr Pesola explains that some people in the study used non-allocated products, for example people in the nicotine patch group were also found to be using e-cigarettes. This meant that if they then quit there was uncertainty as to whether the quitting behaviour was due to the nicotine patches or to the e-cigarettes. The study team had anticipated this behaviour and pre-specified that they would exclude people who were abstinent and who had used non-allocated products. Dr Pesola reports that after doing this e-cigarettes were found to be more effective than patches. The safety profile was similar for both study products, however, low birthweight (

    • 18 min
    May 2022 Podcast with Neal Benowitz

    May 2022 Podcast with Neal Benowitz

    Jamie Hartmann-Boyce and Nicola Lindson discuss emerging evidence in e-cigarette research and interview Neal Benowitz. In this episode Associate Professor Jamie Hartmann-Boyce and Dr Nicola Lindson discuss the emerging evidence in e-cigarette research and interview Professor Neal Benowitz. This podcast is a companion to the electronic cigarettes Cochrane living systematic review and shares the evidence from the monthly searches.

    Long description
    In the May episode Jamie Hartmann-Boyce talks with Neal Benowitz, Emeritus Professor at the University of California San Francisco, Professor Benowitz practices medicine, cardiology and clinical pharmacology and has a particular interest in tobacco as a major risk factor for cardiovascular disease.
    Professor Neal Benowitz talks to Associate Professor Jamie Hartmann-Boyce about the toxicological data from studies of e-cigarettes. He stresses the importance of comparing e-cigarette use to combustible cigarette use, as the exposure to biomarkers that we can measure is much lower in people who vape than in people who use combustible cigarettes. Professor Benowitz points out that many e-cigarette users have been long-term combustible cigarette users so it is difficult to separate out the effects of each. He highlights the need for longitudinal studies among people who have only used e-cigarettes and have not used combustible cigarettes. Professor Benowitz also discusses the need to look at the different types of e-cigarettes, there are many different products and toxicity will vary between the different e-cigarette devices.
    Jamie and Nicola discuss recent work comparing biomarkers of harm. Exclusive e-cigarette use was associated with lower levels of biomarkers of harm than exclusive use of combustible tobacco, or use of a combination of combustible tobacco. This work was funded by the Oxford University Public Policy Challenge Fund and Cancer Research UK.
    Jamie and Nicola also bring us up to date with the literature search conducted on May 1st 2022. The May search found 2 new studies, 3 new ongoing studies and 2 records linked to previously identified studies. We will include the studies we have found in future updates of the Cochrane review.

    For more information on the full Cochrane review updated in September 2021 see: https://doi.org/10.1002/14651858.CD010216.pub6 or our webpage https://www.cebm.ox.ac.uk/research/electronic-cigarettes-for-smoking-cessation-cochrane-living-systematic-review-1

    • 14 min
    April 2022 with Assistant Professor Alex Liber

    April 2022 with Assistant Professor Alex Liber

    Jamie Hartmann-Boyce and Nicola Lindson discuss emerging evidence in e-cigarette research and interview Alex Liber. In the April episode Jamie Hartmann-Boyce talks with Assistant Professor Alex Liber, Department of Oncology at Georgetown University's School of Medicine, Washington DC, USA. Alex Liber discusses his work at the intersection between markets, public policy, and public health. Alex Liber discusses global tobacco control policy research and tax and price policy. He talks about why different countries react differently to policies and to why tobacco control is seen as the battle of politics, business, and health. He discusses the need for comparative regulatory language. Alex discusses the different e-cigarette policies adopted around the world. Turning to flavours Alex tells us about his work with his colleagues at Georgetown and the University of Michigan on the potential effects of a ban on the sale of menthol cigarettes in the United States. He expanded this work to on menthol cigarettes to look at European sales data and to the effect of the European Union's menthol cigarette ban of menthol cigarette sales in Poland. He reports that although the share of menthol cigarettes sales was 30% in Poland, cigarette sales overall did not drop. He explains that tobacco companies were able to convert their menthol cigarette smokers into standard flavour cigarette smokers, via rebranding cigarettes and flavouring cards. Alex is interested in documenting industry responses. Alex also discusses work looking at e-cigarette flavour bans and temporary bans in the US.

    Jamie and Nicola also bring us up to date with the literature search conducted on April 1st 2022. The April search found 4 new ongoing studies. We will include the studies we have found in future updates of the Cochrane review.

    For more information on the full Cochrane review updated in September 2021 see: https://doi.org/10.1002/14651858.CD010216.pub6 or our webpage

    • 30 min
    March 2022 with Dr Ailsa Butler

    March 2022 with Dr Ailsa Butler

    Jamie Hartmann-Boyce and Nicola Lindson discuss emerging evidence in e-cigarette research and interview Dr Ailsa Butler. Assistant Professor Jamie Hartmann-Boyce and Dr Nicola Lindson talk with Dr Ailsa Butler from the Centre for Evidence Based Medicine, University of Oxford and co-author of the Cochrane review of e-cigarettes for smoking cessation. They discuss the findings of their recent work on the longer term use of e-cigarettes when provided as a tool to stop smoking. In the studies eligible for the review, just over half of people given nicotine e-cigarettes at study start were found to be still using e-cigarettes at six or more months follow up. Of successful quitters, 70% were found to still be using e-cigarettes at six months or more. The longer-term use of nicotine e-cigarettes may reflect their success as a quit smoking aid by preventing relapse to smoking. A key question about long-term e-cigarette use in people who have quit combustible cigarettes is whether it prevents or facilitates relapse or has no effect on relapse. This work was funded by Cancer Research UK and Oxford University's Public Policy Challenge Grant. Jamie and Nicola also bring us up to date with the literature search conducted on March 1st 2022. The search found 1 record linked to a study already identified as ongoing. We will include the studies we have found in future updates of the Cochrane review.

    • 24 min
    February 2022 with Professor Billie Bonevski

    February 2022 with Professor Billie Bonevski

    Jamie Hartmann-Boyce and Nicola Lindson discuss emerging evidence in e-cigarette research and interview Professor Billie Bonevski. In this episode Assistant Professor Jamie Hartmann-Boyce and Dr Nicola Lindson discuss the emerging evidence in e-cigarette research and interview Professor Billie Bonevski. This podcast is a companion to the electronic cigarettes Cochrane living systematic review and shares the evidence from the monthly searches.
    In the February episode Dr Nicola Lindson talks with Professor Billie Bonevski, Professor of Public Health, Flinders University, South Australia. Professor Billie Bonevski discusses her Team's QuiENDS pilot trial of electronic cigarettes for smoking cessation among people in alcohol and other drug treatment. Professor Bonevski discusses e-cigarettes as a harm reduction tool and as part of a solution to high levels of smoking and very low or non-existent rates of quitting seen in this group. The study looks at people using e-cigarettes to quit abruptly or to reducing more gradually. Going forward work has started on the follow up Harmony Trial.
    Jamie and Nicola also bring us up to date with the literature search conducted on February 1st 2022. The February search found 2 ongoing studies and 2 records linked to a studies already included the review. We will include the studies we have found in future updates of the Cochrane review. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

    • 27 min

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