Beyond Longevity

Daphna Stern
  • 5.0 (1)
  • MEDICINA

Beyond Longevity is a deep-dive podcast exploring the cutting edge of longevity science. Through conversations with leading researchers, clinicians, and innovators who are redefining health and longevity, the show unpacks the evidence behind living longer and healthier. Each episode translates complex research into clear, thoughtful discussions, decoding the future of ageing one conversation at a time.

  1. HACE 8 H

    The Promise and Problem of Longevity Testing; Prevention, Access and the Inequality in the field with Niko Hems

    What does good prevention actually look like, and is the longevity industry helping people live better, or simply making health feel more complicated? In this episode of Beyond Longevity, Daphna speaks with Niko Hems, Operations Lead at YEARS, a longevity clinic in Berlin, Germany. Niko brings a rare perspective to the conversation. He works inside the longevity field, but he is not afraid to challenge it. He believes deeply in prevention, yet he is sharply aware of where the industry can go wrong, from over-testing and over-promising to fringe science and the uncomfortable gap between those who can afford cutting-edge healthcare and those who are still struggling to access the basics. His own story makes this especially interesting. At 13, Niko became fascinated by nutrition and fitness while trying to gain weight and feel better in his body. Years later, after completing a Master’s in Longevity Sciences and working inside one of Germany’s leading longevity clinics, he put himself through the kinds of tests many people now associate with the future of health, including genome sequencing, microbiome analysis and more than 200 biomarkers. The result was not quite what he expected. Instead of clarity, much of it created anxiety. Instead of answers, it raised a harder question: when does prevention become too much? This is a refreshingly honest conversation about the promises and problems of modern longevity, the tests that help versus the ones that confuse, the basics that still matter most, and what a more credible, useful and accessible version of prevention could look like. Niko Hems Head of Growth at YEARS. Host of Return on Health podcast. Links: https://nikohems.de https://www.linkedin.com/in/niko-hems/ https://returnonhealth.de/ 00:00 Podcast intro and themes 01:52 Nico’s path into longevity 03:37 Defining longevity and healthspan 04:47 Peakspan explained 06:26 Basics that move the needle 08:32 When testing becomes anxiety 10:07 Inside the Years clinic model 14:26 Cost access and inequality 15:58 Who buys high-end programs 17:55 What 16K actually includes 20:43 Why behaviour change is hard 24:07 Are we really getting healthier 26:04 Lifespan hype vs healthspan focus 28:25 Prevention Over Testing 29:23 Affordable Core Diagnostics 30:50 Why Healthcare Lags 32:58 Fixing Incentives 37:37 Longevity Branding Problem 41:09 Basics That Move Needle 43:28 Free High Impact Habits 46:22 AI And Longevity Future 52:04 Rapid Fire Wrap Up 53:42 Final Takeaways

    56 min

  2. HACE 3 DÍAS ·  CONTENIDO EXTRA

    Beyond Longevity at ViVE, Genomics, Microbiome Testing, and the Future of Personalized Prevention with Brock Hay of BioAro

    In this ViVE conference bonus episode of Beyond Longevity, recorded live at the ViVE event in Los Angeles, the conversation explores how BioAro is seeking to bring different strands of personalised health data together within a single longevity platform. Brock Hay explains BioAro’s approach to integrating genomics, microbiome testing, biomarker analysis, AI-driven interpretation, and personalized supplementation. The central idea is that health and longevity cannot be understood through any single test alone, but require a broader and more connected picture of the individual. The conversation also examines one of the most important questions in modern health technology, namely data privacy. As more companies collect deeply personal biological information, the focus turns to who owns that data, how it is stored, and whether individuals truly remain in control of how it is used. The episode also explores how tools such as telomere testing, methylation analysis, gut microbiome testing, and athlete-focused genomics are being positioned within the wider move towards preventive health. It also considers how far today’s longevity interventions can genuinely take us, and where the limits of current science and commercial promise still remain. Links: https://bioaro.com/ linkedin.com/in/brock-hay-95204471 00:00 Welcome to Beyond Longevity 02:11 Meet Bio Arrow at ViVE 02:23 All in One Longevity Platform 05:02 Genomics Explained Simply 07:03 Privacy and Data Security 09:13 Genes as Prevention Tools 11:23 Methylation and Telomeres 12:08 Who It’s For and Pricing 16:13 Key Longevity Biomarker 17:40 Telomeres and Supplements 22:13 Future of Personalized Medicine 24:10 Gut Microbiome Testing 28:43 Founder Story and Integration 32:38 Research vs Consent 37:06 Vatra Decentralized Storage 38:58 Rapid Fire Longevity Tips 41:06 Closing Takeaways

    43 min

  3. 20 ABR

    Women’s Healthspan, Longevity Hype and Building Credible Health Businesses with Corinne Briaud Manon

    On Beyond Longevity, Corinne Briaud Manon discusses women’s healthspan through the lenses of science, consumer trust and commercial execution, drawing on her experience in major corporates and her work across Green Marlin, which advises health and longevity startups, and LongHER, a women’s healthspan community platform. She explains how the two initiatives connect, including how startups can test their propositions with real consumers, and outlines common early-stage pitfalls such as focusing too much on technical detail and not enough on real consumer need, lacking competitive awareness and structure, and letting passion override business discipline. The conversation explores what “science-backed” should really mean, why longevity is currently a kind of wild west with real credibility risks, and why women’s health needs to become a serious business if it is to address historic underinvestment. Corinne emphasises the importance of getting the basics right first for women, including basic health assessments, body composition, sleep, movement, strength and social connection, rather than spending blindly on superficial solutions. She also points out that access remains skewed towards the privileged and that prevention will need to be properly incentivised if it is to reach the masses. Instagram: @‌longher_collective https://www.linkedin.com/in/corinne-briaud-manon/ 00:00 Welcome and Guest Intro 01:38 Two Ventures Overview 02:43 Ecosystem Linking Both 04:17 How Longher Helps Startups 06:20 Green Marlin Origin Story 07:39 Startup Gaps and Fixes 11:48 Passion Versus Business 13:00 Spotting Real Innovation 14:44 Authenticity in Longevity Clinics 16:53 From Lab to Market 18:53 What Science Backed Means 20:56 Longevity Wild West 24:09 Why Womens Health Must Scale 28:01 Workplace Healthspan Shift 28:30 Workplace Health Costs 29:19 Menopause Support Programs 30:57 Women Led Health Startups 32:09 Beauty Versus Longevity Hype 33:54 Muscle Health Foundations 35:29 Where To Begin Basics 39:17 Stop Wasting On Superficial 41:14 Longevity Access Inequality 45:19 Prevention Model Shift 50:02 Future Of Longevity Trust 51:49 Rapid Fire Takeaways 55:32 Closing Reflections

    57 min

  4. 13 ABR

    From Lab to Life: Translating Ageing Science into Real-world Solutions with Professor Lorna Harries

    Professor Lorna Harries has spent more than two decades studying why cells age and what might be done about it. In this episode, she explains one of the most overlooked mechanisms in ageing biology, RNA splicing. When cells lose control of this process, they become stressed, dysfunctional and can tip into senescence, a state that contributes to ageing across almost every organ system. She explains what senescent cells actually do, how the signals they release can spread damage from one tissue to another, and why calling them “zombie cells” does not come close to telling the full story. We talk about the possibility of intervening before cells reach an irreversible state, why targeting the biology of ageing itself may matter more than tackling diseases one at a time, and what meaningful rejuvenation should really look like. Prof Lorna also discusses the challenge of turning lab science into therapies through her spin-out SENISCA, her work with L’Oréal, and why conditions such as IPF are an important place to begin. Along the way, she addresses the tougher questions too, including how longevity science moves from promise to treatment, where the field risks drifting into hype, and whether these advances will be available to the many or only the few. Links: http://www.senisca/ http://www.iscarna.com/ https://teamrna.wixsite.com/harrieslab https://experts.exeter.ac.uk/1873-lorna-harries Innovate UK ICURe Programme https://iuk-business-connect.org.uk/programme/icure/ 00:00 Podcast Intro Guest Setup 01:50 Meet Professor Harris Basics 02:16 DNA RNA Explained 03:38 RNA Splicing And Ageing 05:48 What Senescent Cells Do 07:38 Reversing Senescence Window 09:01 Fat Tissue And Faster Ageing 11:01 Splicing As Central Hallmark 12:11 Rejuvenation Discovery Story 13:52 From Lab To Spinout Company 16:41 Translating Science To Products 19:17 Therapy Targets IPF And Beyond 21:45 Why Translation Often Fails 23:19 Defining Real Rejuvenation 25:14 Avoiding Hype In Longevity 27:17 Who Is Lagging Behind 27:37 Regulatory Mindset Shift 28:47 Trials Built for Ageing 29:28 Scepticism and Overhype 31:25 Is Ageing a Disease 32:49 Policy and Demographic Timebomb 33:48 Advocacy and Communication 35:24 Personal Ageing Habits 36:24 Key Unasked Questions 39:15 Longevity for the Rich 41:43 Access via NHS and Patents 45:06 Rapid Fire and Myths 49:05 Closing Reflections

    51 min

  5. 10 ABR ·  CONTENIDO EXTRA

    ViVE Bonus: Marc Zemel on Real-Time Hemodynamic Monitoring and Early Deterioration Detection in Critical Care

    Recorded at the 2026 VIVE conference in Los Angeles, this Beyond Longevity mini-series episode features Mark Zemel, co-founder and CEO of Retia Medical, discussing the company’s hemodynamic monitoring technology that turns continuous bedside physiological signals into real-time clinical insights for high-risk surgery and critical care. Marc explains Retia’s aim to detect early deterioration, guide diagnosis and therapy, and avoid the unreliability, invasiveness and complexity of older tools, noting deployment in 75 US hospitals and distribution via Medtronic, plus presence in 18 countries. He highlights FDA clearance for Argos Infinity enterprise software, which extends insights across the hospital and to clinicians’ phones and laptops, and shares a case where rapid detection of falling stroke volume revealed bleeding during AAA repair. The conversation covers workflow-first design, interoperability, cybersecurity, regulatory strategy, and a future path from ICU to broader wards and ultimately wearables for earlier intervention and preventative care. 00:00 Beyond Longevity Intro 00:44 Meet Mark Zeel 01:40 Rata Medical Mission 02:54 Argos Infinity Launch 03:58 Clinicians Want Real Time 05:19 Surgery Near Miss Story 07:20 Why Accuracy Matters 08:42 Why Algorithms Are Hard 10:08 From ICU To Wearables 12:20 Scaling Distribution Globally 13:22 Plug And Play Integration 15:22 Wearables And Data Overload 18:31 Alerts And Clinical Judgment 20:16 AI As Decision Support 21:56 US Versus Europe Markets 23:09 Wearables Beyond EMRs 23:57 Regulation And Cybersecurity 25:07 FDA And AI Pathways 26:50 Clinician Workflow Design 29:39 Bad Data From Friction 31:58 Open Ecosystems Future 33:25 Prevention And Longevity 35:46 Personal Why Wearables Matter 39:24 From ICU To Early Detection 41:44 Rapid Fire And Wrap

    45 min

  6. 6 ABR

    Why Longer lives Are Changing Work, Business and Society, with Avivah Wittenberg-Cox

    This week’s guest is Avivah Wittenberg-Cox. Avivah advises leaders on gender and generational balance, the future of work, and the longevity economy. She hosts the podcast 4-Quarter Lives, publishes the Substack Elderberries, and writes regularly for Forbes and Harvard Business Review. She is Visiting Faculty at Oxford’s Saïd Business School, co-directs the Longevity Leadership Programme at Católica Lisbon, and has given three TED Talks. In this episode, Avivah and Daphna explore how longer lives are reshaping work, business, and society. Avivah argues that longevity is not just a health story but a structural shift that is forcing organisations to rethink how they are built, how careers unfold, and how different generations work together. She explains why the old pyramid model of the workforce is giving way to a more square demographic reality, with far more balance between younger and older generations than most institutions were designed for. That shift brings real pressure, from pensions to healthcare, but also major opportunities for businesses willing to adapt. The conversation looks at why older workers are still too often overlooked, what businesses lose when they fail to value experience, and why age-inclusive thinking is becoming a strategic advantage rather than a social add-on. More broadly, the episode challenges outdated assumptions about ageing and asks what it would mean to build a society that treats longer lives as a source of possibility, not decline. This episode is a reminder that longevity is not only changing how long we live, but how we work, lead, learn, and contribute across the course of our lives. https://www.avivahwittenbergcox.com/ https://elderberries.substack.com https://elderberries.substack.com/podcast https://www.ted.com/search?q=Avivah+Wittenberg+Cox https://20-first.com/ https://www.forbes.com/sites/avivahwittenbergcox/#61c5a38ebf19 00:00 Longevity Meets Work 02:06 Longevity Mega Trend 03:09 Institutions Lag Behind 05:37 From Gender To Age 07:39 Women And Longer Lives 10:08 Multi Stage Careers 11:26 Rethinking Education Midlife 15:29 Rebranding Old Age 17:54 Opportunity And Ageism 21:24 Fear Of Ageing And Happiness 25:37 Goldman Sachs And AI 27:17 Company First Mover Advantage 28:43 Who Is Leading The Way 29:52 Brands Embrace Pro Ageing 30:21 Longevity In Hospitality 31:12 Retirees As Consultants 31:56 Why Leaders Miss Demographics 35:29 Government Levers And Limits 38:34 The Square Society Shift 40:43 Measuring Longevity Readiness 43:25 Advice Four Quarter Lives 47:54 Designing A Four Quarter Life 53:22 Ageing Better Than Expected 54:46 Rapid Fire And Wrap Up

    58 min

  7. 30 MAR

    NAD, Precision Health & the Science of Living Better for Longer with Dr Jin-Xiong She

    In this episode, Dr Jin-Xiong She, a scientist with more than 400 publications, over 20,000 citations, and more than $100 million in research funding, explains why he left the top tier of academic medicine to pursue something more urgent: finding better ways to detect decline early and protect healthspan before disease takes hold. He shares what nearly 100,000 NAD tests have uncovered and why he believes biomarker baselines could change the way we think about prevention. https://www.jinfiniti.com/ https://www.youtube.com/@ProfJinShe In this episode: 00:00 Welcome and Guest Intro 01:47 From Genomics to Longevity 04:18 T1D TEDDY Study Breakthroughs 06:07 Leaving Academia for Impact 07:37 Healthspan Over Lifespan 10:09 TAO Test Act Optimise 13:20 Choosing Actionable Biomarkers 17:02 Why NAD Tops the List 21:45 NAD Decline and Key Drivers 25:21 Raising NAD Lifestyle vs Supplements 27:51 Athletes' Inflammation and Low NAD 31:54 Optimal NAD Range and Niacin Risks 37:28 SubQ Injections vs Oral NMN Data 41:42 Dosing and Cutting Useless Supplements 43:52 Access Economics and Policy Ideas 46:50 Industry Adoption and Big Names 47:59 Supplement Market Problems 50:17 Rapid Fire and Closing Takeaways 52:04 Final Summary and Goodbye

    53 min

  8. 23 MAR

    Why Governments Still Ignore Ageing, and What Must Change with Dr Ilia Stambler

    What does it take to turn longevity science into real-world policy? In this episode, Daphna speaks with Dr Ilia Stambler, historian of longevity, published author, Chair of the International Longevity Alliance (ILA), and Chief Science Officer and Chairman of Vetek (Seniority) Association, about why advocacy and ecosystem-building may be just as important as the science itself. Dr Stambler shares how the ILA has grown into a global network connecting 76 nonprofits across 66 countries, organising international conferences, and running the annual Longevity Day (1st October) and Longevity Month (October) campaigns. He points to concrete wins, including efforts to support the inclusion of ageing-related conditions in the ICD and the WHO's work programme. The conversation gets honest about the real barriers to progress. Dr Stambler argues the problem isn't convincing governments that ageing matters, it's getting them to treat it with urgency. Despite ageing representing one of the largest disease burdens globally, it remains chronically underfunded and deprioritised, in part because the research timelines required don't fit neatly into political cycles. He also reflects on the deeper intellectual questions underpinning the field: how to balance holism and reductionism, why historical perspective is essential for longevity researchers, and how the same patterns of enthusiasm, scepticism, and neglect have repeated across centuries of rejuvenation science. Looking ahead to 2030, Dr Stambler highlights the need for better public education, evidence-based criteria for evaluating interventions, and growing grassroots motivation, because ultimately, he believes, a longer and healthier life begins with wanting one. In This Episode: How the ILA operates across 66 countries and what it's achievedWhy governments acknowledge ageing but still fail to act on itThe long funding timelines longevity research demands — and why that's a political problemWhich countries are currently leading on longevity policyWhy solo science isn't enough and advocacy changes outcomesThe "Death Valley of ideas" and how to get research across itBalancing holism and reductionism in longevity scienceWhy the history of rejuvenation science keeps repeating itselfWhat meaningful success in this field actually looks like. Ilia Stambler, PhD Chairman and CSO. Vetek (Seniority) Association – The Movement for Longevity and Quality of Life, Israel http://www.longevityisrael.org/ Chairman. International Longevity Alliance (ILA) http://www.longevityalliance.org/ Fellow. Department of Science, Technology and Society, Bar-Ilan University, Israel https://sts.biu.ac.il/ Author. A History of Life-Extensionism in the Twentieth Century; Longevity Promotion: Multidisciplinary Perspectives; Healthy Longevity: Policies and Practices http://longevityhistory.com https://www.longevityhistory.com/about-the-author/ 00:00 Welcome and Guest Intro 01:28 Staler Background and Mission 03:18 What the ILA Does 04:04 Key Wins and Campaigns 05:25 Public Misconceptions 07:27 Getting Governments to Act 09:14 Funding Research Long Term 10:49 Education and Conferences 12:05 Which Countries Lead 15:22 Why Advocacy Beats Solo Science 17:38 Advocacy Success Stories 20:48 Breaking Longevity Silos 21:23 Holism vs Reductionism 22:28 Why History Matters 24:17 Death Valley of Ideas 25:49 Rejuvenation Patterns Repeat 27:42 Misunderstood Longevity History 29:22 Balance and Modesty 31:23 Measuring Real Success 34:59 Making Longevity Policy 36:09 Rapid Fire Takeaways 38:58 Final Wrap Up

    40 min
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Beyond Longevity is a deep-dive podcast exploring the cutting edge of longevity science. Through conversations with leading researchers, clinicians, and innovators who are redefining health and longevity, the show unpacks the evidence behind living longer and healthier. Each episode translates complex research into clear, thoughtful discussions, decoding the future of ageing one conversation at a time.

Información

  • Creador
    Daphna Stern
  • Años de actividad
    2 k
  • Episodios
    16
  • Clasificación
    Apto
  • Copyright
    © Copyright 2026 Daphna Stern
  • Mostrar sitio web
    Beyond Longevity

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