Human 3 with Brom and Sam

Brom Rector and Sam Tabone
  • 5.0 (6)
  • TECHNOLOGY
  • UPDATED WEEKLY

Interviews with the scientists, founders and investors driving Human 3 - the next epoch of health, wellbeing and performance. Topics include brain-computer interfaces, genetic medicine, psychedelics, longevity, AI and more. Hosted by Brom Rector and Sam Tabone - founders of XEIA Venture Partners, a venture capital fund investing in Human 3. More at www.xeiavp.com

  1. $HIMS Q2 Results - our take as healthcare venture capitalists

    AUG 5

    $HIMS Q2 Results - our take as healthcare venture capitalists

    Brom Rector and Sam Tabone from XEIA Venture Partners - a VC firm that invests in the future of human health, wellbeing and performance - discuss $HIMS Q2 results and the HIMS business more broadly. We spend a lot of time discussing the legality of HIMS current FDA strategy and how/if HIMS can compete in a world with increasing competition from players like Function Health and Superpower. This is not financial advice. www.xeiavp.com

    1h 24m

  2. JUL 30

    Investing in Psychedelic BioTech [August 2025 webinar replay]

    Watch the video recording on YouTube: https://youtu.be/BM6x59oMnKg?si=qF0xDvgUMvU60ctP 2025 has been the start of a bull period for psychedelic medicine. ​Psychedelic Biotechs like GH Research, Compass Pathways and Lykos Therapeutics are releasing impressive, late stage clinical trial data ​Capital is following the data: Cybin just raised $500M and Johnson and Johnson's Ketamine-inspired antidepressant Spravato broke $1B+ / year of topline. ​A new administration seems surprisingly interested in accelerating the FDA approval of psychedelics as treatments for mental health disorders ​Learn how top VCs and LPs are mapping and allocating to this exciting space in this special event designed for family offices and HNWIs. ​You will learn: ​The contrasting approaches that biotech and pharma are taking to commercialize psychedelic medicine ​Where we see the highest-leverage points for investing ​Lessons from past failures ​And of course there will be plenty of time for interaction and Q&A ​This event is run by Brom Rector and Sam Tabone of XEIA, a venture capital fund that invests in "Human 3 - the next epoch of human health, wellbeing and performance". As part of their Human 3 thesis, they have invested in 8 psychedelic medicine companies from pre-seed to pre-IPO.

    58 min
  3. Compass and ATAI latest news + are Psychedelics BACK in 2025?!

    JUL 29

    Compass and ATAI latest news + are Psychedelics BACK in 2025?!

    The past few years have been rough for psychedelic and shroom stocks, but recent news from ATAI (and Recognify), Compass Pathways and GH Research + positive regulatory tailwinds from RFK and MAHA make me think that Psychedelics are back on the menu in 2025. In this video I discuss: (0:00) - why psychedelics are hot again in 2025 (5:45) - latest thoughts on Compass a month after their Phase 3 topline data (9:45) - thoughts on ATAI / Recognify, and how this feeds back into our psychedelic macro theme Join our investing in psychedelics webinar www.psybio.org

    16 min
  4. Bryan Johnson's Neuralink competitor - with Kernel CEO Ryan Field

    JUL 22

    Bryan Johnson's Neuralink competitor - with Kernel CEO Ryan Field

    Ryan Field is the CEO of Kernel, a brain-computer interface company founded by Bryan Johnson. Kernel is a cutting edge, non-invasive BCI that uses fNIRS to image the brain. Imagine if getting an MRI was as easy as putting on a bike helmet: that's Kernel in a nutshell. Kernel is developing several applications on top of their device including (A) predicting which antidepressant you will respond best to and (B) BrainAge, a cognitive assesment that tells you how young your brain is relative to your chronological age. Ryan joins Brom Rector and Sam Tabone on the podcast to discuss: (0:00) - Ryan’s background (7:30) - history of Kernel (10:00) - non-invasive VS invasive BCI (Kernel vs NeuraLink) (25:00) - what Kernel can do: depression treatment response + brain age (31:00) - Kernel's AI: black box or hand tuned features (45:00) - How Kernel can detect cognitive impairment (55:30) - Kernel's alcohol study (58:00) - Kernel vs cheap neurotechand more!Get your Brain Age measured at https://www.kernel.com/brainage

    1h 33m

  5. JUL 15

    How to start a VC fund

    I interviewed Michael Huseby to learn about his life story and his new book: Fundamentals: Your Friendly Guide to Investment Funds and SyndicationsThis is a great listen for anyone interested in starting an investment fund or interested in making the transition from "practitioner" to "practitioner operator", like Michael did when leaving BigLaw to start his firm, and like I did when leaving the hedge fund I was to start my own fund. We cover: 0:00 - Michael's backstory. Big Law. Going blind. The road to Entrepreneurship16:30 - from legal practitioner to legal entrepreneur23:30 - how TIL is different, a law firm run like a startup37:30 - how Michael is growing his firm + law in the age of AI44:30 - trends in the private markets world51:00 - what are the attributes of successful fund managers54:00 - 506(b) vs 506(c)1:03:00 - most common mistakes people make when starting a fund1:07:30 - Michael’s views fund-in-a-box services like AngelList, Carta and SydecarMichael's law firm: https://www.investmentslawyers.com/Michael's book: https://www.amazon.com/Fundamentals-Friendly-Guide-Investment-Syndications-ebook/dp/B0FCMJL1G8/ref=sr_1_1

    1h 20m

  6. JUL 12

    Beyond Neuralink - Investing in Brain Computer Interfaces [webinar replay]

    Replay of our webinar on investing in brain computer interfaces. Join our upcoming July 30th event on investing in psychedelic biotech: psybio.org

    1h 9m
  7. Designing Novel Brain Drugs with Xylo Bio

    JUL 8

    Designing Novel Brain Drugs with Xylo Bio

    Xylo is a biotech startup that is using computational methods to design novel brain drugs to treat mental health disorders and neurodegeneration. Many of their drug candidates are inspired by naturally occurring psychedelic drugs but are specifically designed to not induce hallucinations. Xylo's cofounders Josh Ismin and Sam Banister join Brom Rector and Sam Tabone to discuss: (3:25) - Xylo origins + why design novel psychedelic molecules? 10:30) - How Xylo’s AI approach is different than other non-hallucinogenic psychedelic companies like Gilgamesh and Delix (21:30) - What is the head twitch response? (25:30) - How Xylo’s drugs are different than other psychedelics even though they hit the same receptor (5HT2a) (26:30) - How Lykos’ failure to get MDMA approved impacts Xylo (32:00) - Running trials in Australia (43:00) - How has Xylo has evolved over the years (50:30) - How will AI change drug discovery (53:00) - How much of the neuro receptor space has been characterized (56:00) - Is Xylo bullish or bearish on AIMore on Xylo here: https://www.xylo.bio/ More on Brom, Sam and XEIA here: www.xeiavp.com

    1h 1m
  8. The BioIndustrial Revolution: Why Peter Thiel and Chris Sacca backed Arye's Biomanufacturing Startup

    JUN 30

    The BioIndustrial Revolution: Why Peter Thiel and Chris Sacca backed Arye's Biomanufacturing Startup

    Arye Lipman is the cofounder of Biosphere, a startup that recently raised millions of dollars from Peter Thiel's Founders Fund and Chris Sacca's Lower Carbon Capital to Unleash Industrial Biomanufacturing at scale. Biosphere is replacing the 1950's steam bioreactor with a modern, UV-enabled design that reduces the capital intensity of biomanufacturing. Arye joins Brom Rector and Sam Tabone to share how biomanufacturing promises to unlock a new era of global abundance and American sovereignty. We also discuss: (0:00) - what is biomanufacturing (5:00) - biomanufacturing vs traditional manufacturing (10:00) - how Biosphere's UV bioreactors are 10x better than traditional bioreactors (28:30) - what a 10x cost decrease in biomanufacturing unlocks. (35:00) - can we grow a steak without a cow? (42:00) - how biosphere raised from Founders Fund and Lower Carbon Capital (51:00) - is biomanufacturing "woke climate" or American Dynamism? (55:50) - how Biosphere is working with the DOD (1:07:30) - Trump’s view on biomanufacturing (1:12:00) - Consciousness, dolphins and the CIA Check our biosphere here: https://www.biosphere.io/

    1h 21m
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5
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About

Interviews with the scientists, founders and investors driving Human 3 - the next epoch of health, wellbeing and performance. Topics include brain-computer interfaces, genetic medicine, psychedelics, longevity, AI and more. Hosted by Brom Rector and Sam Tabone - founders of XEIA Venture Partners, a venture capital fund investing in Human 3. More at www.xeiavp.com

Information

  • Creator
    Brom Rector and Sam Tabone
  • Years Active
    2021 - 2025
  • Episodes
    32
  • Rating
    Explicit
  • Copyright
    © Brom Rector and Sam Tabone
  • Show Website
    Human 3 with Brom and Sam

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