Beyond the Symptoms | An Expert Interview Series by LUF | Live UTI Free

LUF | Live UTI Free

Beyond the Symptoms is an interview series by Live UTI Free (LUF) that explores the science, solutions, and stories behind pelvic health, UTIs, and chronic urinary infections.  Host Melissa Kramer engages in deep conversations with leading medical experts, researchers, and healthcare innovators who share breakthrough insights beyond conventional diagnoses and treatments.  Each episode uncovers cutting-edge research on biofilms, embedded infections, antibiotic resistance, and innovative diagnostic approaches while examining how these conditions impact quality of life. Whether you're a patient navigating recurrent UTIs, interstitial cystitis, or chronic pelvic pain, a healthcare practitioner seeking evidence-based approaches, or a curious mind interested in women's health advocacy, this podcast provides actionable information about complex pelvic health conditions.  Episodes feature world-renowned urologists, urogynecologists, researchers, and patient advocates sharing clinical insights and practical strategies.  Explore our comprehensive resources at liveutifree.com, find additional studies at linktr.ee/liveutifree, watch video interviews on YouTube (@LiveUTIFree), and join our supportive community on Instagram (@liveutifree). 

  1. Phage Therapy for Chronic UTI | Amanda Burkhart & Dr. Mayukh Das with Live UTI Free (LUF)

    SEP 22

    Phage Therapy for Chronic UTI | Amanda Burkhart & Dr. Mayukh Das with Live UTI Free (LUF)

    In this episode, host Melissa Kramer speaks with Amanda Burkardt and Dr. Mayukh Das from Phiogen, a biotechnology company developing bacteriophage (phage) therapeutics for recurrent urinary tract infections (UTIs). They describe how their novel approach utilizes targeted viruses to eliminate UTI-causing bacteria, without harming the microbiome. You’ll hear how Phiogen’s science tackles the most challenging cases, including chronic and antibiotic-resistant UTIs, and why they’re inviting patients to help shape the future clinical trial that Phiogen will be running. If you’ve ever wondered whether phage therapy could be a solution for your chronic UTI, especially if you’ve struggled with negative cultures, biofilms, or treatment resistance, this episode is for you. 🎧 What You’ll Learn in This Episode: How phage therapy works, and why it’s different from antibiotics Why recurrent UTI patients, especially those with antibiotic resistance or biofilms, may benefit most from phage therapy What’s happening behind the scenes to bring an “off-the-shelf” phage treatment to clinical trials The current limitations (e.g., E. coli-only focus) and plans for expanding phage therapy access How YOU can shape the upcoming clinical trial by joining the patient surveyWant to learn more about urinary health? Visit LiveUTIFree.com for expert articles on the latest research, or check out our YouTube channel for a video format.

    47 min
  2. Recurrent UTI & Pelvic Health Explained | Dr. Lindsay Burnett with Live UTI Free (LUF)

    SEP 8

    Recurrent UTI & Pelvic Health Explained | Dr. Lindsay Burnett with Live UTI Free (LUF)

    In this episode of the Live UTI Free Podcast, Melissa speaks with Dr. Lindsay Burnett, a physician-scientist in urogynecology, about the complex relationship between pelvic floor disorders, the urinary microbiome, and recurrent UTI symptoms. Dr. Burnett draws from her clinical and research experience to unpack the often misunderstood differences between acute, recurrent, and chronic UTIs. She also explains how urinary symptoms can be influenced by prolapse, incontinence, urethral sensitivity, and even gut health. This episode is a must-listen for anyone navigating chronic UTI symptoms, especially those who’ve felt dismissed or misdiagnosed. Dr. Burnett offers a patient-centered approach rooted in science and lived experience, addressing the fundamental questions patients ask but rarely get answered. Key Takeaways: UTI testing and diagnosis are broken, but evolving.  Standard urine cultures often miss key pathogens, yet they remain the most widely used method. Dr. Burnett explains why this happens and what newer options (like expanded cultures or catheterized samples) can reveal. Pelvic floor disorders can directly impact UTI risk.  Conditions like prolapse or poor bladder emptying may not cause infections on their own, but they create an environment that makes UTIs more likely and are often overlooked. Care must be collaborative when the evidence is unclear.  When guidelines don’t reflect patient experiences, clinicians and patients need to “walk into the unknown together,” exploring options like intravesical antibiotics, pelvic floor physical therapy, and trial-and-error treatments based on symptom patterns. Want to learn more about urinary health? Visit LiveUTIFree.com for expert articles on the latest research, or check out our YouTube channel for a video format.

    1h 24m
  3. How DNA Sequencing Targets Hidden UTI Causes | Dr. Nick Parkinson with Live UTI Free

    AUG 25

    How DNA Sequencing Targets Hidden UTI Causes | Dr. Nick Parkinson with Live UTI Free

    In this episode of the LUF podcast, host Melissa Kramer sits down with Dr. Nick Parkinson, Scientific Director at the UK-based Systems Biology Laboratory. Driven by a personal experience with his young daughter’s recurring, culture-negative UTIs, Dr. Parkinson’s team developed a groundbreaking DNA‑based test that bypasses traditional culture and PCR methods. Using nanopore sequencing, they analyze urine and vaginal samples directly, identifying bacteria, yeasts, viruses, plasmids, and phages with precision and speed.  Standard UTI tests often miss infections entirely. Dr. Nick Parkinson shares how his team used nanopore DNA sequencing to detect hidden bacteria, including rare strains like Tinnitignum charliei, that culture and PCR can’t find. This advanced method reveals not just what's present, but how each strain behaves and resists treatment. He also explains why testing both urine and vaginal samples is crucial for uncovering hidden reservoirs that may be causing recurrent UTIs. What You’ll Learn from This Episode What limits current UTI tests like culture and PCR, and how nanopore sequencing overcomes them. Why matching the strain, not just the species, matters for understanding how UTI bugs behave and resist treatment. How this tool may reshape both diagnosis and treatment planning, including antibiotic guidance and recognition of underexplored conditions like overgrowth syndromes.Want to learn more about urinary health? Visit LiveUTIFree.com for expert articles on the latest research, or check out our YouTube channel for a video format.

    1h 14m
  4. Hiprex for UTI Prevention & Treatment | Dr. Catriona Anderson with Live UTI Free (LUF)

    JUN 9

    Hiprex for UTI Prevention & Treatment | Dr. Catriona Anderson with Live UTI Free (LUF)

    Host Melissa Kramer interviews Dr. Catriona Anderson, a UK-based women’s health doctor and founder of a diagnostics lab focused on enhanced UTI testing. Together, they explore Hiprex—what it is, how it works, and its potential role in managing recurrent and chronic UTIs. Dr. Anderson breaks down the science behind this over-the-counter urinary antiseptic, explaining its dual-action mechanism, how it functions as both bactericidal and bacteriostatic, and why it stands out as a non-antibiotic option. The episode also provides practical guidance on taking Hiprex, managing side effects, and combining it safely with other therapies, such as vitamin C, D-mannose, and probiotics. 3 Key Takeaways: Hiprex’s Dual Mechanism Makes It Unique: Hiprex activates in acidic urine and produces formaldehyde, which kills bacteria directly. It also prevents bacteria from multiplying, making it both bactericidal and bacteriostatic. Safer Long-Term Use with Careful Management: Hiprex has fewer side effects than long-term antibiotics and can be used safely for extended periods. Still, dosage and timing may need to be adjusted based on symptoms, pH level, and lifestyle factors. Better Testing is Essential: Standard urine culture often misses infections, especially in chronic cases. Dr. Anderson’s lab uses extended culture methods and more precise sample handling to uncover hidden bacteria.Want to learn more about urinary health? Visit LiveUTIFree.com for expert articles on the latest research, or check out our YouTube channel if you prefer video format.

    1h 5m

Ratings & Reviews

5
out of 5
2 Ratings

About

Beyond the Symptoms is an interview series by Live UTI Free (LUF) that explores the science, solutions, and stories behind pelvic health, UTIs, and chronic urinary infections.  Host Melissa Kramer engages in deep conversations with leading medical experts, researchers, and healthcare innovators who share breakthrough insights beyond conventional diagnoses and treatments.  Each episode uncovers cutting-edge research on biofilms, embedded infections, antibiotic resistance, and innovative diagnostic approaches while examining how these conditions impact quality of life. Whether you're a patient navigating recurrent UTIs, interstitial cystitis, or chronic pelvic pain, a healthcare practitioner seeking evidence-based approaches, or a curious mind interested in women's health advocacy, this podcast provides actionable information about complex pelvic health conditions.  Episodes feature world-renowned urologists, urogynecologists, researchers, and patient advocates sharing clinical insights and practical strategies.  Explore our comprehensive resources at liveutifree.com, find additional studies at linktr.ee/liveutifree, watch video interviews on YouTube (@LiveUTIFree), and join our supportive community on Instagram (@liveutifree). 

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