a16z Podcast

The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

  1. HACE 42 MIN

    Charlie Kirk and the Rise of Political Violence

    In this episode of Honestly with Bari Weiss, we share a special conversation featuring a16z general partner Katherine Boyle in the wake of Charlie Kirk’s shocking assassination. Katherine reflects on what courage means in a culture where words and debate are increasingly met with violence. Drawing on faith, history, and her own response to recent tragedies, she discusses the idea of martyrdom, not only in its most extreme sense, but also in the small, everyday choices to speak the truth despite risk.   Timecodes:  0:00  Introduction  0:49  Remembering Charlie Kirk 2:46  The Meaning of Martyrdom 4:49  Courage and the Choice We Face 9:16  Returning to Normalcy 10:35  The Age of Extremes 12:15 Words, Violence, and the Next Generation 14:10  Reclaiming the Center 18:18  The Power and Danger of Rhetoric 21:55  The Call to Speak Up   Resources:  Listen to more from Honestly: https://podcasts.apple.com/za/podcast/honestly-with-bari-weiss/id1570872415 Find Bari on X: https://x.com/bariweiss Find Katherine on X: https://x.com/KTmBoyle   Stay Updated:  If you enjoyed this episode, be sure to like, subscribe, and share with your friends! Find a16z on X: https://x.com/a16z Find a16z on LinkedIn: https://www.linkedin.com/company/a16z Listen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYX Listen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711 Follow our host: https://x.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated: Find a16z on X Find a16z on LinkedIn Listen to the a16z Podcast on Spotify Listen to the a16z Podcast on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg   Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    24 min
  2. The Death of Search: How Shopping Will Work In The Age of AI

    HACE 4 DÍAS

    The Death of Search: How Shopping Will Work In The Age of AI

    The web is unhealthy, and AI agents are about to rewrite how we shop. In this episode, a16z General Partner Alex Rampell and Partner Justine Moore explore how AI agents will change commerce and the implications for Google’s business model, affiliate marketing, online shopping, and more.   Timecodes:  0:00 Introduction  0:12 The Role of AI Agents in Commerce 1:28 Affiliate Marketing & Impulse Buys 4:02 Observing Consumer Behavior & AI 6:08 Dynamic Pricing & E-commerce Trends 7:20 Online vs. Offline Shopping Behaviors 10:09 The Challenge of Attribution in Commerce 12:19 Aggregators, Brands, and Business Models 15:24 Trend Cycles & Single SKU Retailers 17:49 Google, Search, and the Freemium Model 22:41 The Unhealthy Web & Commercialization 26:04 Video Reviews & Trust in Commerce 29:10 The Costco Model & Consumer Trust 33:15 AI’s Impact on Different Types of Purchases 39:56 The Future: Specialized Shopping Agents 40:16 Opportunities for New Durable Companies 44:18 The Merchant Side: Infrastructure for AI Agents   Resources:  Read the article: http://a16z.com/ai-x-commerce/ Find Alex on X: https://x.com/arampell Find Justine on X: https://x.com/venturetwins   Stay Updated:  If you enjoyed this episode, be sure to like, subscribe, and share with your friends! Find a16z on X: https://x.com/a16z Find a16z on LinkedIn: https://www.linkedin.com/company/a16z Listen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYX Listen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711 Follow our host: https://x.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated: Find a16z on X Find a16z on LinkedIn Listen to the a16z Podcast on Spotify Listen to the a16z Podcast on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg   Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    45 min
  3. How OpenAI Built Its Coding Agent

    HACE 5 DÍAS

    How OpenAI Built Its Coding Agent

    OpenAI’s Codex has already shipped hundreds of thousands of pull requests in its first month. But what is it really, and how will coding agents change the future of software? In this episode, General Partner Anjney Midha goes behind the scenes with one of Codex’s product leads- Alexander Embiricos - to unpack its origin story, why its PR success rate is so high, the safety challenges of autonomous agents, and what this all means for developers, students, and the future of coding.   Timecodes: 0:00 Intro: The Vision for AI Agents 1:25 Codex’s Origin and Naming 3:20 Early Prototypes and Agent Form Factors 6:00 Cloud Agents: Safety and Security 9:40 Prompt Injection and Attack Vectors 12:00 PR Merging: Metrics and Transparency 17:00 The Future of Code Review and Automation 20:00 User Adoption: Internal vs. External Surprises 22:00 Multi-Turn Interactions and Product Learnings 29:30 Best-of-N, Slot Machine Analogy, and Creativity 33:00 Human Taste, Iteration, and Collaboration 40:00 AI’s Impact on Software Engineering Careers 45:00 Education, CS Degrees, and AI Integration 49:00 Prototyping, Hackathons, and Speed to Magic 55:00 Legacy Code, Modernization, and Global Adoption 1:00:00 Enterprise, Security, and Air-Gapped Environments 1:05:00 Product Roadmap and Future of Codex 1:10:00 Advice for Founders and Startups 1:15:00 Education Reform and Project-Based Learning 1:20:00 Hiring, Building, and New Grad Advice   Resources:  Find Alex on X: https://x.com/embirico Find Anjney on X: https://twitter.com/AnjneyMidha   Stay Updated:  If you enjoyed this episode, be sure to like, subscribe, and share with your friends! Find a16z on X: https://x.com/a16z Find a16z on LinkedIn: https://www.linkedin.com/company/a16z Listen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYX Listen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711 Follow our host: https://x.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated: Find a16z on X Find a16z on LinkedIn Listen to the a16z Podcast on Spotify Listen to the a16z Podcast on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg   Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    1 h y 20 min
  4. Faster Science, Better Drugs

    HACE 6 DÍAS

    Faster Science, Better Drugs

    Can we make science as fast as software?  In this episode, Erik Torenberg talks with Patrick Hsu (cofounder of Arc Institute) and a16z general partner Jorge Conde about Arc’s “virtual cells” moonshot, which uses foundation models to simulate biology and guide experiments.  They discuss why research is slow, what an AlphaFold-style moment for cell biology could look like, and how AI might improve drug discovery. The conversation also covers hype versus substance in AI for biology, clinical bottlenecks, capital intensity, and how breakthroughs like GLP-1s show the path from science to major business and health impact.   Resources: Find Patrick on X: https://x.com/pdhsu Find Jorge on X: https://x.com/JorgeCondeBio Stay Updated: Find a16z on X Find a16z on LinkedIn Listen to the a16z Podcast on Spotify Listen to the a16z Podcast on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg   Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    56 min
  5. 12 SEP

    Ben Horowitz: Why Hesitation is a CEO’s Worst Enemy

    In this conversation from Lenny’s Podcast, Ben Horowitz joins Lenny to discuss the psychological muscle every founder needs, why hesitation can be fatal for CEOs, when it’s time to replace a founder, and how to normalize failure while building confidence. They also explore the Databricks founding story, investing in Adam Neumann after WeWork, whether AI is in a bubble, where the real opportunities lie, and Ben’s work with the Paid in Full Foundation supporting hip-hop pioneers. The result is a candid look at leadership, product management, and what it takes to build enduring companies.   Timecodes:  00:00 Introduction  00:22 The Psychology of Leadership & Decision-Making 02:41 Leadership lessons from Shaka Senghor 07.56 Struggle, Pain, and Growth as a CEO  10:15 Running toward fear and why hesitation kills companies 19:35 Who shouldn’t start a company 22:36 The Databricks story: thinking bigger 24:54 Managerial leverage and CEO psychology 28:06 When founders should be replaced as CEOs 31:20 Normalizing failure for CEOs 37:57 Counterintuitive lessons about building companies 42:31 “Good Product Manager/Bad Product Manager” 48:21 Product managers as leaders 51:16 Why a16z invested in Adam Neumann after WeWork 56:23 Is AI in a bubble? 01:02:43 The biggest opportunities in AI 01:12:51 Why U.S. leadership in AI matters 01:18:53 The Paid in Full Foundation for hip-hop pioneers 01:23:18 Lightning round: book recommendations, products, and life mottos   Resources:  Find Ben on X: https://x.com/bhorowitz Find Ben on LinkedIn: https://www.linkedin.com/in/behorowitz/ Watch more of Lenny’s Podcast: https://www.youtube.com/@LennysPodcast Check out Lenny’s newsletter here: https://www.lennysnewsletter.com   Stay Updated:  Find a16z on X: https://x.com/a16z  Find a16z on LinkedIn: https://www.linkedin.com/company/a16z  Listen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYX?si=3E8B3qT9TyiwAHJ7JnaKbg Listen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711 Follow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated: Find a16z on X Find a16z on LinkedIn Listen to the a16z Podcast on Spotify Listen to the a16z Podcast on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg   Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    1 h y 36 min
  6. Inside the $13T Mortgage Machine

    11 SEP

    Inside the $13T Mortgage Machine

    The $13T U.S. mortgage market serves 50M homeowners but still runs on decades-old software.  In this episode, a16z GP Angela Strange hosts Tim Mayopoulos (ex-CEO of Fannie Mae and ex-president of Blend), Mike Yu (co-founder and CEO of Vesta), and Andrew Wang (co-founder and CEO of Valon) to unpack why standardization and regulation slow change, and how modern loan-origination and servicing platforms, cleaner data, and AI can cut costs, boost transparency, and reduce errors. They also discuss policy levers that could speed innovation and what a true one-tap mortgage could look like.   Timecodes:  00:00 Introduction  00:59 The Scale and Structure of the US Mortgage Market 01:33 Why Mortgage Tech is Slow to Change 02:00 Challenges of Standardization and Regulation 03:41 The Human Side of Home Buying 07:43 Old Software and Its Impact on Homeowners 11:16 Data Transparency and Capital Markets 13:17 Building New Mortgage Infrastructure: LOS and Servicing 16:22 Operational Challenges and Opportunities in Servicing 22:04 Driving Digital Adoption at Fannie Mae 25:15 Modernizing Data and Appraisals 28:27 Core Replacement vs. Wrappers: Tech Strategies 35:29 AI in Mortgage: Today and Tomorrow 40:42 AI, Regulation, and the Future of Compliance 43:54 Advice for Lenders Preparing for an AI Future 47:49 Visions for the Future of Mortgages   Resources:  Find Angela on X: https://x.com/astrange Find Tim on LinkedIn: https://www.linkedin.com/in/timothy-j-mayopoulos-56972a45/ Find Andrew on LinkedIn: https://www.linkedin.com/in/wangandrewd/ Find Mike on LinkedIn: https://www.linkedin.com/in/mikeyu1/   Stay Updated:  Find a16z on X: https://x.com/a16z  Find a16z on LinkedIn: https://www.linkedin.com/company/a16z  Listen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYX?si=3E8B3qT9TyiwAHJ7JnaKbg Listen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711 Follow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    55 min
  7. Chris Dixon on How to Build Networks, Movements, and AI-Native Products

    10 SEP

    Chris Dixon on How to Build Networks, Movements, and AI-Native Products

    Why do some consumer products explode into networks that reshape the internet, while others fade away? Today on the podcast, a16z general partners Anish Acharya and Chris Dixon take on that question. Anish invests in AI-native consumer products and the next wave of consumer tech. Chris is best known for his work in Web3 and network economies, and he’s also led some of a16z’s biggest consumer bets. Together, they cover the history and power of consumer networks, the exponential forces that shape how they grow, and what it all means for founders building in the age of AI.   Timecodes: 00:00 Introduction  00:43 The Power of Networks in Tech 02:19 Moore’s Law, Composability, and Network Effects 06:39 Building Networks: Tools vs. Networks 10:49 Brand, Pricing, and Consumer Software Trends 14:33 Movements, Communities, and Niche Markets 20:02 Decentralization, AI, and the Open Web 24:45 Platform Shifts and the Idea Maze 29:55 Native vs. Skeuomorphic Technologies 36:14 Open Source, Policy, and the Future of AI 42:03 Closing Thoughts & Outro   Resources:  Find Chris on X: https://x.com/cdixon Find Anish on X: https://x.com/illscience   Stay Updated:  Let us know what you think: https://ratethispodcast.com/a16z Find a16z on Twitter: https://twitter.com/a16z Find a16z on LinkedIn: https://www.linkedin.com/company/a16z Subscribe on your favorite podcast app: https://a16z.simplecast.com/ Follow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated: Find a16z on X Find a16z on LinkedIn Listen to the a16z Podcast on Spotify Listen to the a16z Podcast on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg   Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    43 min
  8. Mark Cuban on the NBA, Cost Plus Drugs, and How to Fix Politics

    9 SEP

    Mark Cuban on the NBA, Cost Plus Drugs, and How to Fix Politics

    What happens when AI collides with salesmanship, streaming-era sports, and healthcare? In this episode, Erik Torenberg is joined by Mark Cuban, entrepreneur, Dallas Mavericks co-owner, and founder of Cost Plus Drugs. Topics include fiery group chats and how dissent sharpens thinking, the sales playbook of modern politics, and concrete fixes for U.S. healthcare like ending PBM opacity, publishing real prices, and government-backed patient financing. Mark also explains how AI is pushing media from “social” to algorithmic, why he expects millions of models, and why ESOPs are an underrated wealth engine. He shares what he’d build today and weighs in on NBA economics under the new collective bargaining agreement. Timecodes:  00:00 Introduction  00:47 Salesmanship, Politics, and Social Media 04:05 AI, Algorithms, and the Future of Media 06:29 Fragmentation of Social Platforms 09:04 Political Messaging & Economic Populism 12:05 Wealth, Equity, and Employee Ownership 16:39 AI’s Impact on Education and Healthcare 21:32 Fixing the US Healthcare System 29:39 Entrepreneurship in the Age of AI 33:38 Business Success, Sports, and Investments 35:32 NBA Economics and Team Building 50:44 Personal Priorities & Closing Thoughts   Resources:  Find Mark on X: https://x.com/mcuban   Stay Updated:  Let us know what you think: https://ratethispodcast.com/a16z Find a16z on Twitter: https://twitter.com/a16z Find a16z on LinkedIn: https://www.linkedin.com/company/a16z Subscribe on your favorite podcast app: https://a16z.simplecast.com/ Follow our host: https://x.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated: Find a16z on X Find a16z on LinkedIn Listen to the a16z Podcast on Spotify Listen to the a16z Podcast on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg   Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    1 h y 1 min
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The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

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