CReATe Podcast

CReATe Consortium
  • 5.0 (4)
  • HEALTH & FITNESS
  • UPDATED MONTHLY

CReATe Connect podcasts are short recorded interviews on topics we hope will be of interest to patients with ALS and other motor neuron diseases.

  1. 12/10/2025

    ALS Untangled Series Ep. 64 - Wahls Protocol

    The Wahls Protocol is a diet that may reduce inflammation, oxidative stress, and mitochondrial dysfunction.  Although these are plausible mechanisms for slowing ALS progression, we discuss the fact that there are no actual data to support this hypothesis, and there are risks which are especially important to consider in people living with ALS.

    17 min

  2. 11/17/2025

    ALS Untangled Series Ep. 63 - Psilocybin

    Psilocybin is a psychedelic chemical derived from mushrooms.  It is under study for mood problems in people with ALS.  Here we review its plausible mechanisms for slowing ALS progression.  But there are no data from preclinical models, trials or case reports that currently support this benefit.  And there can be serious risks to using this chemical.

    10 min

  3. 10/20/2025

    ALS Untangled Series Ep. 62 - Ashwagandha

    Here we review ashwagandha a nutritional supplement that has plausible mechanisms for slowing ALS, promising pre-clinical evidence, and a reasonable safety profile.  There is one person with ALS who experienced a reversal of symptoms on a cocktail of treatments that included ashwagandha.  Cases like this are difficult to interpret as there can be multiple explanations for a person experiencing an ALS reversal.  We have not found any other cases suggesting improvement on this product.  We hope to see the data from the completed phase 2 trial soon.

    17 min

  4. 09/24/2025

    CReATe Author Series Ep. 16 - Dr. Johnathan Cooper-Knock on Exercise and ALS

    Dr. Johnathan Cooper-Knock is a neurologist and clinical lecturer at the University of Sheffield.  His research focuses on genetic causes of ALS.  Here he discusses his recent publication “Extreme exercise in males is linked to mTOR signalling and onset of amyotrophic lateral sclerosis”.

    19 min

  5. 09/09/2025

    ALS Untangled Series Ep. 61 - Zinc

    Here we review Zinc supplements as a treatment for ALS.  These are inexpensive, reasonably safe at certain doses, and are easy to acquire.  They have plausible mechanisms by which they could slow ALS progression.  However, the data from people living with ALS is not very convincing yet.

    17 min

  6. 06/02/2025

    CReATe Author Series Ep. 15 - Drs. Terry Heiman-Patterson and Michael Benatar on Clinical Guidance for ALS/FTD at-risk carriers

    Dr. Terry Heiman-Patterson is a neurologist and professor at Temple University and the director of the Center for Neurodegenerative Disorders and the MDA/ALS Center of Hope.  Dr. Michael Benatar is a Professor of Neurology and Chief of the Neuromuscular Division and Executive Director of the ALS Center at the University of Miami.  In this podcast they will be discussing their recent publication “Guidance for clinical management of pathogenic variant carriers at elevated genetic risk for ALS/FTD”.

    33 min

  7. 05/01/2025

    CReATe Author Series Ep. 14 - Drs. Ruben van Eijk and Michael Benatar on Phase 2 Trials and ALS

    Dr. Ruben van Eijk is an associate professor in the Department of Neurology at the University Medical Center Utrecht in the Netherlands as well as a statistical consultant and medical statistician for the clinical trial methodology group at the Julius Center also in Utrecht.  Dr. Michael Benatar is a Professor of Neurology and Chief of the Neuromuscular Division and Executive Director of the ALS Center at the University of Miami.  They will be discussing their recent publication “Rethinking phase 2 trials in amyotrophic lateral sclerosis”.

    37 min

  8. 02/18/2025

    CReATe Author Series Ep. 13 - Dr. Benatar on Prognostic Markers and ALS

    Dr. Michael Benatar is a Professor of Neurology and Chief of the Neuromuscular Division and Executive Director of the ALS Center at the University of Miami.  Here he discusses the recent publication “Prognostic clinical and biological markers for amyotrophic lateral sclerosis disease progression: validation and implications for clinical trial design and analysis”.

    27 min
See All (81)

Ratings & Reviews

5
out of 5
4 Ratings

About

CReATe Connect podcasts are short recorded interviews on topics we hope will be of interest to patients with ALS and other motor neuron diseases.

Information

  • Creator
    CReATe Consortium
  • Years Active
    2018 - 2025
  • Episodes
    81
  • Rating
    Clean
  • Copyright
    © Copyright CReATe Consortium
  • Show Website
    CReATe Podcast

You Might Also Like