8 episodes

Obesity and diabetes are increasingly a burden in modern populations, and whilst the contributions of our lifestyles are well-known, other aspects of the conditions are less clear. Our podcasts on diabetes and obesity highlight the work of our scientists and clinicians to understand the underlying factors of lifestyle and metabolism, molecular and genetic mechanisms, and less common forms of diabetes, to improve management and treatment of these conditions.

Diabetes and Obesity Oxford University

    • Education

Obesity and diabetes are increasingly a burden in modern populations, and whilst the contributions of our lifestyles are well-known, other aspects of the conditions are less clear. Our podcasts on diabetes and obesity highlight the work of our scientists and clinicians to understand the underlying factors of lifestyle and metabolism, molecular and genetic mechanisms, and less common forms of diabetes, to improve management and treatment of these conditions.

    • video
    Diabetes in Young Adults

    Diabetes in Young Adults

    Dr Katharine Owen talks about the different types of diabetes in young adults. There are more forms of diabetes than the commonly known type 1 and type 2. Correct diagnosis of the different forms of diabetes is difficult because of the overlap of symptoms. The implications of incorrect diagnosis are huge, as some forms of diabetes respond better to certain treatments than others. Dr Katherine Owen investigates the different characteristics of monogenic diabetes with the aim of creating systematic diagnostics, and implementing that in clinical care. The ultimate aim is to promote personalised medicine for everybody with diabetes. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

    • 5 min
    • video
    Diabetes and Genomics

    Diabetes and Genomics

    Professor Mark McCarthy tells us how genomics helps us understand diabetes. Diabetes is a major challenge for global healthcare, with social, health and economic costs projected to exceed trillions of dollars over the next 50 years. Professor Mark McCarthy, the Robert Turner Professor of Diabetes, leads a multidisciplinary research team including clinicians, nurses and lab-based research staff. Professor McCarthy's research focusses on translating gene identification and genetic information into advances in the functional understanding, and clinical management of this disease. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

    • 8 min
    • video
    Personalised Diabetes Treatment

    Personalised Diabetes Treatment

    Professor Stephen Gough talks about the development of personalised diabetes treatment. An estimated 500 million people worldwide will be affected by diabetes within the next fifteen years. Professor Stephen Gough believes that you cannot give every patient affected by diabetes the same treatment, since people react differently to treatments. Professor Gough looks at the reasons behind differences in the way that people react to diabetes treatments, in order to improve care and reduce the health and economic costs associated with the disease. Professor Gough aims to provide the right treatment to the right person at the right time in their disease for optimum results.

    • 5 min
    • video
    Liver Fat Metabolism

    Liver Fat Metabolism

    Dr Leanne Hodson talks about her research on liver fat metabolism. Understanding liver fat metabolism is extremely important, as the health risks associated with fatty liver disease can include diabetes, heart disease and liver cancer. Fatty liver disease is defined as having over 5 percent liver fat, and a 'silent disease' as many people are not diagnosed. Dr Leanne Hodson is working on finding targets for new medications, which will help lower the risk of accumulating liver fat leading to fatty liver disease. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

    • 7 min
    • video
    Metabolism of Fatty Acids

    Metabolism of Fatty Acids

    Dr Barbara Fielding talks about her research on the metabolism of fatty acids. Obesity continues to have a major impact on health care services in the UK. Dr Barbara Fielding believes that nutritional advice should be based on a thorough understanding of metabolic responses to food ingestion, and that it is important to investigate the metabolism of dietary fat after both single and multiple meals. By tracing fat atoms from meals into the blood, Dr Barbara Fielding's research into individual metabolic responses to food ingestion may lead to targeted, customised, and more effective nutritional advice for obese and overweight patients. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

    • 4 min
    • video
    Genetics and Diabetes

    Genetics and Diabetes

    Dr Anna Gloyn talks about her research on the genetics of diabetes. An estimated 366 million people worldwide now suffer from diabetes and the global epidemic is getting worse. Dr Anna Gloyn uses genetic variants in humans as tools to identify critical regulatory pathways for insulin secretion and action. Current research projects are focused on the translation of genetic association signals for type 2 diabetes and glycaemic traits into molecular mechanisms for diabetes and clinically useful tools. Understanding how genes relate to types of diabetes will enable better diagnosis and treatment for patients. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

    • 4 min

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