Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health

Joanne Kennedy

The Histamine Well is a podcast for health practitioners and patients alike, bridging the gap between complex science and practical understanding. With a focus on histamine, methylation, and related health topics, the show translates advanced concepts into actionable insights for practitioners while empowering patients with accessible, evidence-based knowledge.Your host, Joanne Kennedy, is a naturopath and expert in histamine intolerance, MTHFR, and methylation. She is also an author and runs an online group coaching program for practitioners and students on histamine and methylation. Jo loves breaking down complex science into clear, easy-to-understand language, offering practical tips and the latest insights to empower you to take charge of your health.

  1. 4D AGO

    30. Hydrogen Sulfide SIBO Explained: Symptoms, Testing & Treatments with Rosaria Nithart

    In this episode of The Histamine Well Podcast,  Joanne sits down with Rosaria Nithart, a French-based naturopath specializing in digestive health, to uncover the complexities of Hydrogen Sulfide SIBO—one of the most misunderstood forms of Small Intestinal Bacterial Overgrowth (SIBO). Together, they break down how Hydrogen Sulfide SIBO differs from hydrogen- and methane-dominant SIBO, exploring the unique bacteria and biochemical pathways involved. Rosaria shares her step-by-step naturopathic framework for identifying, testing, and treating Hydrogen Sulfide SIBO naturally. The conversation also dives deep into the role of sulfur metabolism, oxalates, and molybdenum in managing symptoms and restoring gut balance. Listeners will learn: The root causes and drivers behind Hydrogen Sulfide SIBOHow to identify key symptoms and understand testing limitationsThe connection between sulfur, oxalates, and bacterial imbalancesPractical treatment strategies that support gut healing without extreme dietsHow Hydrogen Sulfide SIBO links to UTIs, histamine intolerance, and detox pathwaysWhether you’re a practitioner seeking deeper clinical insights or a patient navigating chronic gut issues, this episode offers a clear, actionable approach to understanding and managing Hydrogen Sulfide SIBO naturally.  Connect with Rosaria Nithart: Website: rosarianithart.com | rosarianithart.itFacebook: facebook.com/rosaria.nithartInstagram: @rosarianithartnaturopatheBreath Tests for Hydrogen, Methane & Hydrogen Sulfide: Trio Smart (USA / Canada)– Trio-Smart® — The only 3-Gas SIBO Breath Test: https://www.triosmartbreath.com/Nordic Labs (Europe) – https://nordiclabs.com/EProduct.aspxInvivo Healthcare (UK): https://invivohealthcare.com/Teletest (Spain): https://www.teletest.es/ | https://www.facebook.com/teletest/✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!

    39 min
  2. OCT 13

    29. Healing Chronic Illness Through Nervous System Regulation with Jacqui Raadschelders

    In this episode of The Histamine Well Podcast, Joanne Kennedy sits down with physiotherapist and neuro-rehabilitation specialist Jacqui Raadschelders to explore the link between nervous system dysregulation and chronic illness. You’ll learn how the limbic system, vagus nerve, neuroplasticity, and brain retraining techniques play a vital role in recovery from conditions influenced by trauma, mold exposure, and stress. Jacqui shares her journey from traditional physiotherapy to a holistic, trauma-informed approach—highlighting the impact of emotions, beliefs, and environment on healing. Key topics include: Fight, flight, and freeze responsesThe role of the limbic system in chronic illnessPractical vagus nerve toning exercisesEmotional regulation and belief system shiftsBrain retraining for long-term resilienceTailored strategies to regulate and recalibrate the nervous systemWhether you’re a practitioner, student, or someone navigating chronic illness, this conversation offers practical tools and evidence-based insights for restoring balance and supporting your nervous system health. Enrol in the Regulate Your Nervous System online program and receive 10% off with the code JOANNE10. This program is for anyone navigating chronic illness, burnout, stress or persistent symptoms who’s ready to understand their body in a new way. Enrol here  ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!

    47 min
  3. SEP 29

    28. Oxalates, Adrenal Fatigue & Blood Sugar Imbalance: Tracy’s Journey to Healing

    In this episode of The Histamine Well Podcast, Joanne is joined by colleague Melanie and patient Tracy, who shares her powerful story of navigating the challenges of oxalates, histamine intolerance, adrenal fatigue, and blood sugar imbalances. Tracy’s journey highlights the complex relationship between oxalates, adrenal and blood sugar imbalances, and oxalate dumping symptoms. With support from Melanie, she has worked through paradoxical reactions to magnesium and B6, learned strategies for managing sulfur metabolism, and discovered the importance of patience and persistence in recovery. Melanie provides expert insights into identifying oxalate issues, tailoring dietary strategies, and supporting detoxification pathways. Together, the conversation emphasizes the importance of professional guidance, careful supplementation, and tracking progress when addressing oxalates. Whether you’re a practitioner seeking functional medicine insights or someone personally struggling with oxalates, histamine intolerance, or methylation challenges, this episode offers practical advice and encouragement to support your healing journey. What You’ll Learn in This Episode How oxalates affect adrenal health and blood sugar balanceWhat to know about oxalate dumping symptoms and how to manage themThe role of sulfur metabolism and detox pathways in oxalate sensitivityWhy do some people experience paradoxical reactions to magnesium and B6Dietary and lifestyle strategies for long-term oxalate managementThe link between oxalates, histamine levels, and methylationWhy professional support is crucial for navigating complex health issues Why This Episode Matters Oxalates are often overlooked in discussions about chronic health, but they can play a major role in gut health, nutrient absorption, adrenal function, and histamine intolerance. Tracy’s story shows how challenging—but also how rewarding—it can be to address these issues with the right support and strategies. If you’ve been struggling with fatigue, blood sugar swings, or unexplained reactions to supplements, this conversation offers valuable guidance. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!

    1h 9m
  4. SEP 15

    27. Why Blood Tests & Functional Medicine Tests Aren’t the Full Story: Gut, Histamines, Genes, Hormones & More!

    In this episode of The Histamine Well Podcast, host Joanne Kennedy and guest Mariella Gebhardt unpack the nuances of medical testing in functional medicine—and why lab results alone don’t always tell the full story. From histamine intolerance and methylation issues to gut health, Candida, mold exposure, and hormone imbalances, Joanne and Mariela explore the limitations and benefits of testing while emphasizing the importance of case history, symptoms, and environmental factors in shaping treatment. They break down popular tests—including organic acids tests (OAT), microbiome testing, genetic testing, thyroid panels, iron tests, and hormone testing—highlighting when they’re useful, what they may miss, and how to interpret them in real-world practice. Whether you’re curious about functional medicine, women’s hormones, SIBO, oxalates, DAO enzyme activity, or vitamin B12 deficiency, this episode offers clarity on when testing helps—and when it can be misleading. What You’ll Learn in This Episode: Why clinical context matters more than test results aloneHow to approach Candida, mold, and mycotoxin testingThe role of the DAO enzyme in histamine breakdownPitfalls of genetic and gene testing for methylationHow to interpret iron tests, thyroid panels, and hormone markersInsights on organic acids, oxalates, and gut health testingIf you’ve ever wondered whether your test results reflect the whole picture—or how to navigate functional medicine testing with confidence—this conversation will help you understand the bigger picture. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!

    47 min
  5. SEP 1

    26. Mold & Chronic Illness: Symptoms, Testing, and Detox Strategies with Melanie Peers

    Could mold be the missing link in your chronic health puzzle? In this episode of The Histamine Well Podcast, Joanne speaks with Melanie Peers about the hidden impact of mold illness and how it can silently drive histamine intolerance, food sensitivities, and long-term inflammation. You’ll discover how mold exposure can: Raise histamine levels and trigger mast cell activationDisrupt methylation and detoxification pathwaysCause oxalate buildup and sulfur imbalancesLead to neurological, digestive, respiratory, and skin symptomsMelanie shares how to spot the difference between everyday mold allergies and systemic mold-related illness, how to test for mold in your home and body, and what a mold detox protocol can look like in real life. Whether you’re a health practitioner or someone struggling with unexplained symptoms, this episode gives you practical strategies for identifying mold, removing exposure, and supporting recovery. What You’ll Learn in This Episode Key symptoms of mold illness you might be missingHow mold drives histamine intolerance and CIRS (Chronic Inflammatory Response Syndrome)The mold–oxalate connection and why it matters for gut healthEffective mold testing for your home and bodyMold detox strategies and the role of sulfur in recoveryEnvironmental tips for reducing mold exposureReal-life case studies of mold-related illness and recovery ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!

    54 min
  6. AUG 18

    25. Energy Healing Essentials for Perimenopause: A Discussion with Claire Tait

    Perimenopause isn’t just a physical transition — it’s an emotional, spiritual, and energetic shift. In this empowering episode of The Histamine Well Podcast, Joanne speaks with Claire Tait, a holistic kinesiologist and intuitive energy healer, about how to navigate perimenopause with greater balance, calm, and self-awareness. Claire shares her expertise on how kinesiology, reiki, acupressure, yoga, and other holistic practices can support women during this powerful life stage. You’ll learn how to regulate your nervous system, address anxiety naturally, and embrace the spiritual metamorphosis of perimenopause. This conversation is filled with practical rituals, personal insights, and empowering perspectives to help you surrender to the changes, reconnect with yourself, and thrive during midlife. What You’ll Learn in This Episode: Emotional & spiritual transitions of perimenopauseHow self-awareness supports hormonal and emotional healthKinesiology: blending Eastern and Western healing methodsReiki, acupressure, and yoga for grounding and calmNatural approaches to easing anxiety during perimenopauseThe role of the nervous system in healingHow intermittent fasting impacts women’s healthEmbracing aging and rejecting societal pressuresThe energetics of female empowerment✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!

    1h 2m
  7. AUG 11

    24. Histamine & Anxiety – How High Histamine Triggers Fight-or-Flight Symptoms

    Can histamine be the hidden reason behind your anxiety? In this episode, I break down how histamine acts as a neurotransmitter in the brain — and why an overload can leave you wired, anxious, and unable to relax. We dive into how methylation, estrogen, mold, and gut inflammation (including SIBO and oxalates) all feed into the histamine-anxiety loop. Whether you're a practitioner treating patients with anxiety or someone who’s tried everything to feel better — this episode gives you a deeper lens into the hidden biochemical drivers of mental health symptoms. If you've ever felt overstimulated, panicked, or like anxiety hits out of nowhere, you're going to want to hear this one. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!

    31 min
5
out of 5
14 Ratings

About

The Histamine Well is a podcast for health practitioners and patients alike, bridging the gap between complex science and practical understanding. With a focus on histamine, methylation, and related health topics, the show translates advanced concepts into actionable insights for practitioners while empowering patients with accessible, evidence-based knowledge.Your host, Joanne Kennedy, is a naturopath and expert in histamine intolerance, MTHFR, and methylation. She is also an author and runs an online group coaching program for practitioners and students on histamine and methylation. Jo loves breaking down complex science into clear, easy-to-understand language, offering practical tips and the latest insights to empower you to take charge of your health.

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