Rational Wellness Podcast

Rational Wellness

Rational Wellness Podcast hosted by Dr. Ben Weitz helps you unlock the latest science in functional medicine, nutrition, wellness and health, so you can optimize your body and mind. Weekly interviews with experts in Functional Medicine and Wellness with focus on gut health, hormones, inflammation, wellness, brain health, nutrition, health and longevity. You'll discover evidence-based strategies to reverse chronic disease, balance your biology, and extend your healthspan — from cutting-edge lab testing and nutrition to personalized lifestyle interventions. Past guests include Dr. Dale Bredesen, Dr. Jeffrey Bland, and Dr. Mark Pimentel and many of the most trusted voices in functional and integrative medicine and the wellness world. Subscribe today to learn practical tools you can use right now for better health and wellness.

  1. 3d ago

    Environmental Toxins and Health with Dr. Joe Pizzorno | Rational Wellness Podcast 477

    Environmental Toxins, Wildfire Smoke, and Practical Detox Strategies with Dr. Joe Pizzorno   Dr. Ben Weitz hosts the Rational Wellness Podcast and interviews Dr. Joe Pizzorno on latest research about environmental toxins, emphasizing wildfire smoke risks, PM2.5 penetration, rapid body and brain distribution, and links to neurological, respiratory, and cardiovascular disease. Pizzorno argues toxins are a primary, solvable driver of chronic illness and that oxidized cholesterol reflects toxic exposure more than cholesterol itself. Practical protections include running high-MERV (≥12, ideally 16) HVAC filtration 24/7, avoiding incense, and supporting detox with glutathione (liposomal or via NAC), increased and diverse fiber to reduce toxin reabsorption, and saunas to sweat profusely (except PFAS "forever chemicals," which don't excrete via sweat). They discuss mercury release from forest fires, microplastics and gut binding, arsenic reduction from rice cooking, water filtration (carbon block, RO for arsenic), endocrine disruptors like bisphenols, and toxin assessment using GGTP, ALT, eGFR, and urinary 8-OHdG rather than challenge tests.   01:02 Meet Dr Joe Pizzorno 02:24 Wildfires and Toxic Exposure 05:21 PM2.5 and Systemic Damage 07:24 Cholesterol Oxidation and Toxins 09:35 Home Air Filtration Tips 11:25 Mercury From Forest Fires 13:15 Glutathione and NAC Basics 14:41 Binders and Fiber Strategy 17:26 Persistent vs Nonpersistent Toxins 19:21 Saunas and Forever Chemicals 21:47 Microplastics and Gut Binding 24:13 Post Fire Cleanup Safety 25:21 Arsenic in Water Rice Chicken 27:54 Whole House Water Filters 29:08 Chlorine Fluoride Tradeoffs 31:08 Plastic Bottles and Bisphenols 31:54 Endocrine Disruptors Explained 33:58 Phytoestrogens vs Xenoestrogens 35:49 Safer Drinkware and Cookware 36:37 Testing Toxins Smarter 39:49 Biomarkers GGTP ALT eGFR 44:37 Detox Nutrition and Glutathione 46:54 Toxins and Autoimmune Disease 48:22 Cure Versus Suppression 53:44 Final Thoughts and Outro   Dr. Joe Pizzorno is one of the founders of the modern naturopathic medicine and also the Functional Medicine movement, founding president of Bastyr University, editor of the Textbook of Natural Medicine, and one of the world's leading authorities on environmental toxins and chronic disease. He's the author of at least 14 outstanding books, including The Toxin Solution and a textbook on toxins that he cowrote with Walter Crinion, Clinical Environmental Medicine and he continues to publish groundbreaking research on the role of environmental toxicants in human health. Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

    Environmental Toxins and Health with Dr. Joe Pizzorno | Rational Wellness Podcast 477
  2. Aug 26

    Newest Developments in SIBO Treatments with Dr. Mark Pimentel | Rational Wellness Podcast 476

    View the Show Notes For This Episode Newest Developments in SIBO Treatments with Dr. Mark Pimentel | Rational Wellness Podcast 476   Dr. Mark Pimentel on SIBO/IBS: 3-Gas Breath Testing, Hydrogen Sulfide, Methane, Diet & Emerging Treatments Dr. Ben Weitz welcomes Dr. Mark Pimentel to discuss new research on IBS and overgrowth syndromes, including hydrogen SIBO, intestinal methanogen overgrowth (IMO), and intestinal sulfide overproduction (hydrogen sulfide). Pimentel explains that hydrogen on breath tests is a marker for bacteria like E. coli and Klebsiella and that slowed motility enables overgrowth; he also distinguishes bloating vs abdominal distension and critiques Rome criteria for excluding bloating. They review Trio-Smart three-gas breath testing, lactulose vs glucose, timing and cutoffs (methane ≥10 ppm; hydrogen sulfide >2), and evidence that elevated hydrogen sulfide correlates with severe diarrhea and gut cellular dysfunction. They cover GLP-1 effects on motility, FoodMarble pros/cons, low fermentation diet, elemental diet (MBIOTA), probiotics, new therapies (rifaximin + timed-release NAC; methane enzyme inhibitor), and a Cedars-Sinai IBS-D trial recruiting in Los Angeles. 00:00 Show Intro and Mission 01:00 Meet Dr Mark Pimentel 03:12 Is Hydrogen Always Bad 05:11 Bloating vs Distension 08:40 Where SIBO Bugs Come From 10:30 Why Slow Transit Drives Overgrowth 12:50 Three Gas Breath Testing 16:21 Breath Test Critiques Answered 20:09 Cutoffs for Positive Tests 23:27 Hydrogen Sulfide Gut Damage 24:57 GLP1 Drugs and SIBO 27:37 Methane Weight Gain Explained 29:17 FoodMarble Pros and Cons 30:42 Low Fermentation Diet Debate 32:27 White Bread Misconceptions 33:25 Rifaximin Plus NAC Trial 35:10 New Methane Blocking Drug 36:26 Methane Treatment Challenges 38:00 Methanogens Balance And Phages 40:05 Palatable Elemental Diet 41:22 Next Gen Anaerobic Probiotics 44:23 IBS Versus IBD Relationship 46:31 Hydrogen Sulfide Options 47:40 Mast Cells Mold And Motility 49:18 Vagus Nerve Confusion 51:30 Future Of Overgrowth Syndromes 52:42 Trial Signup And Wrap Up 53:26 Podcast Outro And Clinic Info   Dr. Mark Pimentel is one of the world's leading authorities on the gut microbiome and small intestinal bacterial overgrowth, or SIBO. He serves as Executive Director of the Medically Associated Science and Technology Program at Cedars-Sinai Medical Center in Los Angeles and has dedicated more than two decades to unraveling the complex relationship between the gut microbiome and disorders such as irritable bowel syndrome. Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

    Newest Developments in SIBO Treatments with Dr. Mark Pimentel | Rational Wellness Podcast 476
  3. Aug 18

    The Microglia are a Key to Brain Health with Dr. David Perlmutter | Rational Wellness Podcast 475

    View the Show Notes For This Episode Dr. David Perlmutter on Microglia, Metabolism, and a New Paradigm for Neurodegenerative Disease Dr. Ben Weitz introduces the Rational Wellness Podcast and interviews neurologist and author Dr. David Perlmutter about his upcoming book, Brain Defenders, describing a neuroscience shift from neuron-centered thinking to the brain's immune cells (glia/microglia) as key drivers of neurodegeneration. Perlmutter argues microglial polarization (supportive M2 vs destructive M1) is upstream of protein accumulations like beta-amyloid, alpha-synuclein, and phosphorylated tau, and is strongly influenced by lifestyle-driven metabolic health (blood sugar, insulin resistance, lipids, blood pressure), systemic inflammation, gut dysbiosis, and blood–brain barrier integrity. They discuss prevention, multimodal treatment approaches (e.g., Bredesen and Ornish/Tanzi), mitochondrial dysfunction, exercise, supplements (olive oil polyphenols, vitamin D, CoQ10, urolithin A, spermidine, dihydromyricetin, rosmarinic acid), and emerging drug strategies including TREM2 targeting and GLP-1 agonists, noting benefits and risks. 00:00 Show Intro 01:02 Meet David Perlmutter 03:04 Microglia Paradigm Shift 05:21 Beyond Amyloid Drugs 09:08 Multimodal Reversal Evidence 13:34 Neurons vs Microglia Basics 16:46 Gut Inflammation Link 19:24 Blood Brain Barrier Aging 21:22 Mitochondria Microglia Switch 25:52 Why Diseases Differ Epigenetics 29:54 Tau Is Downstream Too 31:40 Brain Defender Diet Metabolism 35:14 GLP1s For Parkinsons 42:57 Diet Types CGM Keto Fiber 48:46 Supplements For Microglia 52:04 Rapamycin NAD Hype Check 54:34 Wrap Up Preorder Book 55:03 Podcast Outro Dr. David Perlmutter, board-certified neurologist, six-time New York Times bestselling author, with some of his most popular books being Brain Grain, Brain Maker and Drop Acid and his new book, Brain Defenders.  His website is DrPerlmutter.com. Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

    The Microglia are a Key to Brain Health with Dr. David Perlmutter | Rational Wellness Podcast 475
  4. Aug 17

    Rational Wellness Podcast Episode 020: Bioidentical Hormones for Women with Dr. Jill Stocker

    Rational Wellness Podcast Episode 020: Female Hormones with Dr. Jill Stocker Dr. Jill Stocker discusses the use of bioidentical estrogen and progesterone hormones to help women restore their youth and vigor and their "juiciness".  I laid out the topic first by talking about how it was believed for decades that estrogen was protective for the heart, which is why women have a lower risk of heart attack than men until menopause and then their risk increases equal to men's.  There was however, concern about the increased risk of breast and ovarian cancer.  When the Women's Health Initiative study was published in 2002 it shook the field of women's hormone replacement therapy by demonstrating an increased risk of heart attack and stroke in women who took equine (from horses) estrogen and synthetic progestins (Premarin and PremPro). But these results do not necessarily apply to the use of bioidentical hormones, which are much safer. Dr. Jill Stocker can be reached at   https://www.jillstocker.com/  or here:  http://www.thebodywellusa.com/   Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

  5. Aug 11

    Breast Implant Illness with Dr. Robert Whitfield | Rational Wellness Podcast 474

    View the Show Notes For This Episode Breast Implant Illness with Dr. Robert Whitfield | Rational Wellness Podcast 474 Dr. Ben Weitz interviews Dr. Robert Whitfield, a board-certified plastic surgeon specializing in breast reconstruction and explant surgery using an integrative approach with functional medicine, genomics, nutrition, and environmental medicine. They discuss breast implant illness (fatigue, brain fog, joint pain, GI and autoimmune-like symptoms), implant types, and why implant-based reconstruction is more common than microsurgical autologous tissue reconstruction. Whitfield reviews evidence and proposed mechanisms including bacterial biofilm contamination, oxidation of oleic acid in breast tissue, immune activation (T-, B-, and plasma-cell responses), and findings from PCR testing in 694 consecutive cases showing 29% bacterial contamination. He outlines preparation and recovery strategies (genetics, toxicity, gut, hormones, sleep, nutrition), surgical capsulectomy and pocket rinses, limited role for antibiotics, implant surveillance after 8–10 years, and alternatives like fat transfer. 00:00 Show Intro and Mission 00:59 Meet Dr Rob Whitfield 02:45 Implant History and Types 03:46 Microsurgery Reconstruction Explained 07:50 Implants Versus Own Tissue 09:30 Silicone Leakage and Immune Limits 11:48 Explant Surgery and Capsule Removal 13:42 Biofilm Mechanism and Oxidation 17:05 Evidence and Susceptibility Factors 20:43 Preop Prep and Recovery Protocol 23:20 Antibiotics PCR and Pocket Rinse 25:20 Heavy Metals Sauna and BIA ALCL 27:40 Textured Implant Recall Guidance 28:32 Implant Lifespan and Imaging 29:58 When to Remove Implants 30:34 Ruling Out Other Causes 31:51 Mold and Parasite Protocols 33:45 Autoimmunity and Biomarkers 36:01 Recovery Lifestyle Basics 37:45 Diet and Protein Focus 39:23 Why BII Is Missed 41:48 Implant Choices and Risks 43:14 Alternatives Like Fat Transfer 45:48 Aftercare and Recovery Tech 48:10 Finding Surgeons and Resources Dr. Robert Whitfield is a board-certified plastic surgeon who specializes in breast reconstruction, explant surgery, and optimizing recovery through an integrative approach that combines reconstructive surgery with functional medicine, genomics, nutrition, and environmental medicine. Over the past decade, Dr. Whitfield has become one of the leading physicians studying what has become known as Breast Implant Illness, or BII—a constellation of symptoms that can include fatigue, brain fog, joint pain, gastrointestinal complaints, autoimmune-type symptoms, and other chronic health issues that some women associate with their breast implants. Dr. Whitfield can be found at DrRobertWhitfield.com Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

    Breast Implant Illness with Dr. Robert Whitfield | Rational Wellness Podcast 474
  6. Aug 7

    Mold Remediation with Michael Rubino | Rational Wellness Podcast 473

    View the Show Notes For This Episode Mold, Indoor Air Quality, and Building a Healthy Home with Michael Rubino Dr. Ben Weitz introduces the Rational Wellness Podcast and interviews mold remediation and indoor air quality expert Michael Rubino of Home Cleanse and the Change the Air Foundation about mold, indoor air quality, and creating a healthy home. Rubino describes entering the field after Hurricane Sandy, observing people remaining ill despite cosmetic restorations driven by insurance limits and cost-cutting, and notes an EPA statistic that people spend about 90% of their time indoors. They discuss widespread water damage in homes, mold and bacteria as linked problems, and how new construction can develop mold from poor material handling and inadequate moisture control. Rubino addresses wildfire-related indoor contamination (heavy metals, VOCs, ash), recommends dust and VOC testing, critiques fogging and bleach-based approaches, emphasizes HVAC maintenance and filtration, and outlines the foundation's education, research, and policy goals. 00:59 Meet Michael Rubino 01:50 Why Indoor Air Matters 03:26 Hurricane Sandy Wakeup 05:40 Insurance Drives Remediation 06:45 Mold Coverage Caps 08:57 Denied Claim Story 11:13 How Common Is Water Damage 12:14 Mold In New Builds 17:49 Dried In Explained 19:09 Fire Smoke Toxins Indoors 22:35 Testing After Fires 27:15 Drywall And Safer Walls  29:14 Mold Inspection Dust Test 30:10 ERMI Confusion Solved  32:48 Ordering And Next Steps 32:57 Mold Plus Bacteria 34:02 Mold vs Bacteria Basics 34:54 Next Wave Testing 35:41 Bleach Fogging Myths 37:00 Porous vs Nonporous Cleanup 40:42 What to Toss or Keep 42:26 Tape Testing Belongings 45:12 Laundry and Air Purifiers 46:37 Filters MERV and Ozone 50:30 Ventilation Fires Humidity 53:02 Change the Air Mission 57:01 HVAC Lungs of Home 01:01:20 Clinician Takeaways Wrap 01:03:21 Where to Find More Michael Rubino is one of the country's leading experts on mold remediation and indoor air quality. He's the founder of HomeCleanse, Chairman of the Change the Air Foundation, and he is also a council-certified Mold Remediator by IICRC and ACAC and a contributing member, sponsor, and speaker for the Indoor Air Quality Association. He is also the host of the Never Been Sicker podcast. Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

    Mold Remediation with Michael Rubino | Rational Wellness Podcast 473
  7. Jul 31

    How to Eat for Peak Athletic Performance | Dr. Philip Goglia | RWP #18

    View the Show Notes For This Episode Dr. Philip Goglia explains to Dr. Ben Weitz how to improve athletic performance through nutrition. [If you enjoy this podcast, please give us a positive review on Itunes, so more people will find The Rational Wellness Podcast]   Podcast Details Dr. Goglia explained that using the correct macronutrient food pattern that fits each person's metabolism is crucial. This can be determined via a questionnaire and by looking at a lipid profile.  If you are efficient at burning fats and carbohydrates and you consume a vegan diet, it will not work very well. Some people are efficient at burning fats and proteins, some are efficient at burning carbs, and some are efficient at both. Dr. Goglia will often utilize a pretraining cocktail with athletes that includes D-Ribose, L-Glutamine, Taurine, Cinnamon, Calcium and Magnesium, and blackstrap mollases. We'll even add citrulline mallate to it. He mentions that when his athletes have an athletic event in the morning, he will have the athletes eat a "mash" in the evening that includes shredded wheat, apple sauce, almond butter and jam.  They'll wake up with lots of energy.  He may also have the athlete consume this "mash" several hours before an athletic event, such as a basketball game or an athletic event. Dr. Philip Goglia can be reached through his website and for nutrition appointments:  http://www.pfcnutrition.com/

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About

Rational Wellness Podcast hosted by Dr. Ben Weitz helps you unlock the latest science in functional medicine, nutrition, wellness and health, so you can optimize your body and mind. Weekly interviews with experts in Functional Medicine and Wellness with focus on gut health, hormones, inflammation, wellness, brain health, nutrition, health and longevity. You'll discover evidence-based strategies to reverse chronic disease, balance your biology, and extend your healthspan — from cutting-edge lab testing and nutrition to personalized lifestyle interventions. Past guests include Dr. Dale Bredesen, Dr. Jeffrey Bland, and Dr. Mark Pimentel and many of the most trusted voices in functional and integrative medicine and the wellness world. Subscribe today to learn practical tools you can use right now for better health and wellness.

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