Science Magazine Podcast

Science Magazine

Weekly podcasts from Science Magazine, the world's leading journal of original scientific research, global news, and commentary.

  1. Resolving the dispute over the speed of the expanding universe, and seeking new drug targets for cognitive dysfunction

    7H AGO

    Resolving the dispute over the speed of the expanding universe, and seeking new drug targets for cognitive dysfunction

    First up on the podcast, a new path to calculating the Hubble constant. This value for the universe’s speed of expansion is typically determined in one of two ways, one favored by cosmologists, the other by astronomers. But the resulting values from these methods are consistently different. Staff Writer Daniel Clery joins host Sarah Crespi to discuss how reappearing bursts from deep space, lensed by gravity, could resolve the dispute over the speed of the expanding universe. Next on the show, freelance producer Elah Feder talks with Mauro Costa-Mattioli, principal investigator at Altos Labs’ Institutes of Science, about tuning the “integrated stress response” (ISR) in mouse brains. The ISR pathway turns off much of protein synthesis in cells as a response to stressors such as viral infections or oxygen deprivation. The ISR is overactive in some models of cognitive dysfunction—suggesting the downregulated protein synthesis may hamper brain functions such as memory formation. In his paper, Costa-Mattioli and colleagues show turning on the ISR pathway causes memory problems in mice and turning off the ISR can restore function in mouse models of Alzheimer’s disease and Down syndrome. Although this research was in mice, it suggests cognitive dysfunction associated with many different disorders may involve the ISR—making it a good therapeutic target. This week’s episode was produced with help from Podigy. About the Science Podcast Learn more about your ad choices. Visit megaphone.fm/adchoices

    34 min
  2. Resurrection plants, Project Hail Mary, and the trouble with sycophantic AI

    MAR 26

    Resurrection plants, Project Hail Mary, and the trouble with sycophantic AI

    First up on the podcast, Deputy News Editor Martin Enserink talks about so-called resurrection plants. These specialized plants can survive up to 95% water loss, whereas most plants struggle when their water levels dip below 60%. We also hear from Jill Farrant, a professor of molecular and cell biology at the University of Cape Town, about her work dissecting the desiccation survival pathways in resurrection plants and how they might be repurposed to protect crop plants from drought. Next on the show, we’ve all heard of chatbots praising their users for asking the most basic of questions. This bias toward sycophancy extends beyond pleasantries into relationship advice the artificial intelligence (AI) doles out to users. Myra Cheng, a Ph.D. candidate in computer science at Stanford University, joins the show to talk about how this tendency for AIs to be agreeable can lead users to have more confidence in their opinions, to the detriment of their relationships with others. Warning, this last segment contains spoilers for the movie and book Project Hail Mary by Andy Weir. If you’ve seen the movie or don’t mind a bit of extra context, you will hear an analysis of planetary science in the film with astrophysicist and associate curator at the American Museum of Natural History, Jacqueline Faherty. Read the full film review. This week’s episode was produced with help from Podigy. About the Science Podcast Learn more about your ad choices. Visit megaphone.fm/adchoices

    37 min
  3. Matching sounds to shapes, and stories from the AAAS annual meeting

    FEB 19

    Matching sounds to shapes, and stories from the AAAS annual meeting

    First up on the podcast, Newsletter Editor Christie Wilcox, Associate Online News Editor Michael Greshko, and intern Perri Thaler share their experiences from the AAAS annual meeting in Phoenix. Christie recorded on location with David Rand regarding his prize-winning Science paper on using a large language model to combat conspiracy theories. Check out the live version of his team’s Debunk Bot. Michael chats with host Sarah Crespi about the foggy outlook of science in the United States as funding levels and graduate positions decline, and the bright sunshine of young students presenting science posters. And finally, Perri shares her reporting on OpenAI’s contribution to theoretical physics announced at the meeting. Next on the show, we hear about the “bouba-kiki” effect—the tendency for people, no matter their language, to associate round shapes with the nonword bouba and spiky shapes with the nonword kiki. Maria Loconsole, a postdoctoral researcher in the Comparative Cognition Lab at the University of Padova, joins the podcast to discuss why her team looked for this effect in freshly hatched chickens. It turns out these baby birds also make these associations, which suggests the effect has less to do with language and more to do with how vertebrate brains are set up to experience the world. This week’s episode was produced with help from Podigy. About the Science Podcast Learn more about your ad choices. Visit megaphone.fm/adchoices

    41 min
4.3
out of 5
790 Ratings

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Weekly podcasts from Science Magazine, the world's leading journal of original scientific research, global news, and commentary.

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