Tiny Matters

Multitude

Science shapes every facet of our lives, but so much of its influence is overlooked or buried in the past. Tiny Matters is an award-winning science podcast from the American Chemical Society about tiny things — from molecules to microbes — that have a big and often surprising impact on society, past and present. From deadly diseases to forensic toxicology to the search for extraterrestrial life, hosts and former scientists Sam Jones and Deboki Chakravarti embrace the awe and messiness of science and its significance, asking questions like, "how was IVF invented?," "what do glaciers tell us about Earth’s ancient past?," and "why is smallpox the only human infectious disease we’ve eradicated?" New episodes every Wednesday wherever you listen to podcasts.

  1. FEB 4

    The history of clinical trials: From fake exorcisms to testing today

    In 1599, a family in a small French town claimed that their daughter was possessed by a demon called Beelzebub and, despite daily exorcisms, the demon possessing this woman was staying put. So France’s Henri IV set up a royal commission that would try something a little different. The woman would still receive exorcisms, complete with the normal exorcism accoutrements, but with a catch. The priest wouldn’t actually be Catholic, the water in the vessel would be ordinary water, and the Latin used wouldn’t be religious — it would be from Virgil’s famous poem Aeneid. That's because this wasn't actually an exorcism. It was an experiment built on a deceptively simple tool that scientists and doctors still use today to study new medical treatments: a placebo. In this episode, we explore the surprising origins and evolution of one of modern medicine’s most important tools: the clinical trial. We follow the development of experimental design across centuries to modern day randomized controlled trials and the debates about their limitations, trying to answer the question, “How do we know whether a treatment truly works?” Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter! All Tiny Matters transcripts and references are available here. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    37 min
5
out of 5
93 Ratings

About

Science shapes every facet of our lives, but so much of its influence is overlooked or buried in the past. Tiny Matters is an award-winning science podcast from the American Chemical Society about tiny things — from molecules to microbes — that have a big and often surprising impact on society, past and present. From deadly diseases to forensic toxicology to the search for extraterrestrial life, hosts and former scientists Sam Jones and Deboki Chakravarti embrace the awe and messiness of science and its significance, asking questions like, "how was IVF invented?," "what do glaciers tell us about Earth’s ancient past?," and "why is smallpox the only human infectious disease we’ve eradicated?" New episodes every Wednesday wherever you listen to podcasts.

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