Grow Everything Biotech Podcast

Messaginglab

Grow Everything explores the world of biology as technology. Hosts Erum Khan and Karl Schmieder interview leaders and influencers biologizing industries with tools like synthetic biology, precision fermentation, bioprospecting, and more. These companies make biomaterials from waste, cosmetics that restore healthy hair and skin, and delicious cultivated foods in a bioreactor and so much more. Join us as we discuss the latest and greatest across biotech, engineered biology, entrepreneurship, and culture and how this transition is solving healthcare and climate change challenges.

  1. 1d ago

    183. The American Biotech Blueprint: Senator Todd Young on Biodiversity as National Security

    Senator Todd Young joins the Grow Everything podcast to discuss the critical intersection of biotechnology and national security, sharing how his military background, Indiana roots, and role as chairman of the National Security Commission on Emerging Biotechnology shaped his understanding of the bioeconomy as a strategic imperative. From DARPA's shelf-stable powdered blood to the America's Living Library Act — a first-of-its-kind effort to sequence the DNA of flora and fauna across US national parks — Senator Young lays out a compelling vision for distributed biomanufacturing, AI-powered biological discovery, and why the US must act now in what he calls a generational tech competition with China. Karl and Erum also recap highlights from Suppliers Day hosted by the New York Society of Cosmetic Chemists, including biotech-forward exhibitors like Probiotical, Origins by Ocean, Geltor, and the unveiling of BioAtlas — the first open source map of industrial biotech. Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing? Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters: (00:00:00) - Suppliers Day Recap: Biotech Innovations in Beauty & Personal Care(00:07:00) - BioAtlas: The First Open Source Map of Industrial Biotech(00:09:00) - Setting Up the Interview with Senator Todd Young(00:12:00) - How a Marine Turned Senator Became a Biotech Champion(00:16:00) - Why Biology Is Reshaping National Security in the 21st Century(00:20:00) - America's Living Library Act: Sequencing Our National Parks(00:24:00) - Unlocking New Industries from Spider Silk to Bioluminescent Peaches(00:27:00) - The Biggest Barriers Preventing Biotech from Reaching Scale(00:31:00) - A Vision for Distributed Biomanufacturing Across Rural America(00:37:00) - Quick-Fire Questions, Shout-Outs & Closing ThoughtsLinks and Resources: America's Living Library Act of 2026National Security Commission on Emerging BiotechThe Defense Advanced Research Projects Agency (DARPA)National Institute of Standards and TechnologyEngineering silk that is stronger than steelYellowstone Microbe that helped with PCR testsHawkwood’s BioAtlas179. D.C. Climate Week LIVE: The Road to Remake Everything175. Seaweed Is the New Oil: Mari Granström Builds Origin by Ocean143. Sunscreen from Space? Delavie’s Kyle Landry Turns Space Microbes into Skincare31. No Bones About It: Brewing Human and Vegan Collagens with Geltor's Alex Lorestani*** Tickets for the GE Live Ep. NY Tech Week with Roebling ***BioInnovations Events - For 25% off use code: Grow EverythingTopics Covered: National Security Commission on Emerging Biotechnology, America's living library, US Government, Congress, bioeconomy, biotechnology Have a question or comment? Message us here: Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠ Music by: Nihilore  Production by: Amplafy Media

    42 min
  2. May 22

    182. SynBioBeta 2026 Recap, It's Biologist Approved

    Karl and Erum are back from SynBio Beta 2026 in San Jose,  and they brought home an Impact Award. In this special recap episode, they break down the biggest moments from the conference: Neon's audacious plan to engineer chicken eggs as bioreactors, P&G's push into bio ceramides with their Native brand, Twist Bioscience's expansion from DNA synthesis into proteins, and Anthropic's deepening footprint in pharma through its acquisition of Coefficient Bio and partnership with Eli Lilly. They cover panels on the dark proteome, engineered longevity, bio-based colors replacing synthetic dyes, programmable nutrition, and the future of alternative meat,  plus a standing-room-only session on bio-literacy featuring Drew Endy. Along the way, they share stories from the hallways, highlight emerging founders in DNA data storage and space biotech, recap Chef Pierre Thiam's fonio-fueled dinner, and reflect on why strengthening relationships across the bioeconomy matters more than ever. Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing? Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters: (00:00:00) - Grow Everything Wins the SynBio Beta 2026 Impact Award(00:04:30) - Conference Highlights, Listener Meetups & Walking the Exhibit Hall(00:08:15) - Cellular Intelligence, BioBrain AI & Neon's Chicken Egg Bioreactor(00:13:00) - P&G's Bio Ceramides, Twist Bioscience & the Everyday Bio Panel(00:19:30) - Engineered Longevity: Gene Therapy, Matter Bio & Measuring Aging(00:22:30) - AI Meets Pharma: Anthropic, Eli Lilly's Tune Lab & Startup Alliances(00:29:00) - Bruce Friedrich on the Future of Alternative Meat(00:32:00) - Programming Nutrition: When Snacking Meets Medicine(00:36:15) - Bio-Literacy with Drew Endy & the Teaching Disorder(00:42:00) - Panel Recaps: Dark Proteome, Bio Colors, Enzymes & Chef Pierre ThiamLinks and Resources: Links and Resources DocumentTopics Covered: fungi pigments, bio-based colorants, fungal dyes, natural pigments, sustainable color, food colorants, synthetic dyes alternatives, antioxidant pigments, food and beverage, clean ingredients Have a question or comment? Message us here: Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠ Music by: Nihilore  Production by: Amplafy Media

    54 min
  3. May 15

    181. Can Hue Believe It? Gerit Tolborg’s Quest for Pure Color at Chromologics

    Gerit Tolborg, CEO and co-founder of Chromologics, joins Karl and Erum to explore how filamentous fungi can replace synthetic and plant-extracted food dyes with a fermentation-derived red pigment called Tellurin. Gerit shares how a PhD discovery in Denmark led to a venture-backed startup producing a tasteless, odorless, and highly vibrant natural color that performs across processed food categories, from cured meats to bakery to dairy. The conversation covers the real economics of bio-based colorants (including the critical concept of cost-in-use versus kilo price), the challenges of scaling downstream processing from a two-liter reactor to industrial CMOs, and how regulatory pathways at the FDA and EU's FSA are evolving to accommodate fermentation-derived ingredients. Gerit also makes a compelling case for fermentation as a tool for decentralizing and de-risking global supply chains, freeing agricultural land from color crop production and building resilience against climate and geopolitical disruption. Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing? Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters: (00:00:00) - Science News: A Sulfur Exoplanet and What It Means for Extremophile Life(00:03:45) - Is Biotech Winter Over? New IPOs and the Industrial Biotech Outlook(00:08:45) - Introducing Gerit Tolborg and the Chromologics Origin Story(00:10:15) - Discovering Novel Fungal Pigments During a PhD in Denmark(00:13:15) - How Fermentation Produces a Tasteless, Odorless Red Pigment(00:16:30) - Color Vibrancy, Purity, and Competing with Synthetic Dyes(00:19:00) - Building a Mission-Driven Team in the Post-COVID Purpose Economy(00:20:45) - Color as the Forgotten Ingredient and Main Purchase Decision Driver(00:23:00) - Navigating FDA and EU Regulation for Novel Food Colors(00:25:45) - The GMO Perception Gap Between Europe and the US(00:27:30) - Scaling Fermentation: Downstream Processing and Cost Realities(00:30:15) - Cost-in-Use vs. Kilo Price: The Real Economics of Bio-Based Color(00:34:15) - Target Markets: Meat, Bakery, Dairy, Cosmetics, and Beyond(00:37:15) - Clean Labels, E-Numbers, and Naming a Novel Ingredient(00:42:00) - Quick Fire Round and Host TakeawaysLinks and Resources: ChromologicsChromologics raises $ bring its natural colour ingredients closer to market Chr. Hansen - Color House (now Novonesis)Scientists found new sulfur-rich exoplanetTickets for the GE Live Event with Roebling BioInnovations Events - For 25% off use code: Grow EverythingTopics Covered: fungi pigments, bio-based colorants, fungal dyes, natural pigments, sustainable color, food colorants, synthetic dyes alternatives, antioxidant pigments, food and beverage, clean ingredients Have a question or comment? Message us here: Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠ Music by: Nihilore  Production by: Amplafy Media

    51 min
  4. May 8

    180. Fungi in Full Color: Ricky Cassini Reimagines Dye at Michroma

    Ricky Cassini, CEO of Michroma and a former logistics professor turned biotech founder, breaks down why replacing synthetic food dyes is harder than it sounds—and why fermentation-based colorants can outperform both petrochemical dyes and many plant-based “natural” extracts. The conversation covers the core technical constraints that matter to food companies (thermal stability, pH stability, coloring power, flavor neutrality, and supply reliability), why fermentation behaves more like manufacturing than farming, and how regulatory shifts are accelerating demand for bio-based reds and whites (including titanium dioxide alternatives). For an audience following the future of materials and biomanufacturing, this episode is a practical look at how industrial fermentation can modernize a legacy supply chain while meeting performance and consumer expectations. Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing? Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters: (00:00:00) Cold open: “Are we eating printing ink?” + beverage innovation(00:06:55) Conference mode + introducing Ricky Cassini (Michroma)(00:11:05) How a strategy consultant became a fungal pigments CEO(00:14:10) Pigment vs dye: soluble vs dispersed (coffee analogies)(00:16:05) The “food contradiction”: healthy intent, petrochemical reality(00:18:40) Why plant-based reds struggle (cost, stability, supply chain)(00:22:35) Pricing confusion: cost per kilo vs cost-in-use (paint analogy)(00:26:05) What colors Michroma is starting with (red, yellow/orange, white)(00:28:05) Performance specs that matter: heat, pH, light, flavor, reliability(00:30:05) Labeling: “Red 40 / Yellow 5” vs natural naming + how novel fermented colors may be listed(00:33:05) Go-to-market: choosing categories where stability is the bottleneck (dairy, bakery, snacks, vitamins)(00:35:15) Unexpected use cases: aquaculture (salmon) + packaging inks that can migrate into food(00:36:55) Manufacturing strategy: partnering with CJ vs building plants; “time compression” and capex discipline(00:38:10) Scaling pressure points: regulatory timeline + the time/capital reality for novel ingredients(00:39:45) 5–10 year vision: same bright foods, but colors made via microbes (supply chain shift)(00:40:35) Quickfire round: fluorescent food-grade pigments, Gantt charts, and GMO marketing(00:41:40) Wrap + host outro + upcoming episodes and partner promoLinks and Resources: michromaMichroma says fermentation will power next wave of natural colors2025 1st Place Winner of The Future is Fungi Awards159. The Future Is Fungi Awards: From Mushroom Dreams to Real-World ThingsCJ bio - Global FermentationWorld Bio Markets - Our new partnersBioInnovations Events - For 25% off use code: Grow EverythingWorld Bio Markets - PodcastsMars SnackingMolecule Manifesto - Advanced Biotech for Sustainability ReportTickets for the GE Live Event with Roebling Topics Covered: fungi pigments, bio-based colorants, fungal dyes, natural pigments, sustainable color, food colorants, synthetic dyes alternatives, antioxidant pigments, food and beverage, clean ingredients Have a question or comment? Message us here: Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠ Music by: Nihilore  Production by: Amplafy Media

    49 min
  5. May 1

    179. D.C. Climate Week LIVE: The Road to Remake Everything

    Recorded live during DC Climate Week, the Grow Everything team sits down with investors Veronica Breckenridge, Jillian Chase, and Michael Luciani to unpack the real state of the US bioeconomy race with China, why fermentation and scale-up capacity are a persistent bottleneck, and how policy, non-dilutive funding, and better founder execution can close the gap. The panel argues that the US still leads in innovation, AI, and robotics, but needs faster, clearer regulatory pathways and smarter go-to-market strategy, including focusing on high-margin “profit pools” first, designing for manufacturability and downstream processing, and building consumer demand through clearer storytelling about health and product benefits. Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing? Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters: (00:00:00) Live from DC Climate Week: intro and panelist lineup(00:06:00) US vs China: how real is the biomanufacturing gap(00:12:00) Policy signals: DOD, DARPA, and non-dilutive funding(00:18:00) Biggest bottleneck: fermentation infrastructure and scale-up capacity(00:24:00) The “graveyard” lessons: downstream costs and manufacturability(00:30:00) Go-to-market strategy: profit pools vs TAM, and unit economics(00:36:00) Consumer storytelling: health, microplastics, and demand creation(00:42:00) AI + robotics: how they change the bioeconomy race(00:48:00) What unlocks US biomanufacturing: regulation and faster pathways(00:54:00) What to watch next: RNA, peptides, and proof of profitable companiesLinks and Resources: D.C. Climate WeekGraveyard ReportNSCEBSynBioBeta Pass - Discount code: Grow Everything Topics Covered: bioeconomy, biomanufacturing, synthetic biology, fermentation, biological materials, industrial biotech, US-China competition, venture capital, bio-based supply chain, biodiversity Have a question or comment? Message us here: Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠ Music by: Nihilore  Production by: Amplafy Media

    58 min
  6. Apr 24

    178. Pretty in Pigments: Jesse Adler Colors the Future with Pitri

    Karl and Erum talk with Jesse Adler, founder of Pitri, about why color is not just aesthetic, but chemical, biological, and deeply tied to human and environmental health. Jesse traces their path from biomolecular science and biodesign into building fungal pigments that can replace synthetic and animal-derived colorants, starting with the beauty industry as a high-margin, ingredient-driven entry point. The conversation explores how consumer expectations and industrial infrastructure were built around petrochemical dyes, why biological materials are often unfairly judged against synthetics, and what it takes to create drop-in, high-performing pigments from living systems. Along the way, Jesse reframes color as a functional feature in nature, shares early experimentation stories, and points to future opportunities like multifunctional pigments and the “holy grail” of opaque white. Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing? Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters: (00:00:00) Spring in Brooklyn, the BioD series, and why nature’s colors feel “high definition”(00:02:55) The Allbirds “AI pivot” and what meme-stock dynamics look like in real time(00:04:55) A major biotech IPO and the rise of in-licensing drugs from China(00:10:10) Spain’s investment into Boston biotech and signals of a thawing biotech winter(00:12:35) Introducing Jesse Adler and Petri: fungi-grown pigments for beauty(00:15:05) Jesse’s origin story: biomolecular science, creative making, and discovering biodesign(00:18:05) A “molecular worldview”: how materials constantly interact with our bodies and environments(00:20:20) The history of synthetic dyes and the hidden costs of “best available” color(00:23:45) What Petri’s pigments should feel like: drop-in performance plus better provenance(00:26:10) Early lab experiments, unexpected outcomes, and learning through making(00:29:15) Color as function in nature: UV protection, stress response, and antimicrobial roles(00:31:30) Lessons from Pangaia: lab-to-launch gaps, scale, and the mismatch of expectations(00:37:20) Working with living systems: consistency, fermentation “witchcraft,” and honest partnerships(00:40:10) Why petrochemical infrastructure matters: machines, print heads, and manufacturing risk(00:42:35) Where fungal pigments disrupt first: beauty vs textiles vs food(00:47:45) A future where colorants are multifunctional, not inert(00:51:10) Quickfire: misunderstood colors, surprising pigment use, and the “holy grail” of opaque white(00:55:05) Wrap-up: why the color revolution is just beginningLinks and Resources: Pitri BioTo Dye For - Alden Wicker75. Dye Another Day: The New Way to Color Textiles with Colorifix's Orr Yarkoni176. Dare to Commercialize: Damien Perriman’s eXoZymes Playbook15. Meet the Willy Wonka of Algae. Elliot RothD.C. Climate Week 2026 (April 20th - 26th)Brooklyn Botanic GardenAllbirds AI PivotKailera breaks IPO record $625MSynBioBeta Pass - Discount code: Grow Everything Topics Covered: fungi pigments, bio-based colorants, fungal dyes, natural pigments, sustainable color, cosmetic colorants, synthetic dyes alternatives, antioxidant pigments, ingredient storytelling, clean beauty ingredients Have a question or comment? Message us here: Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠ Music by: Nihilore  Production by: Amplafy Media

    1h 2m
  7. Apr 17

    177. Dye Another Day (REPLAY): The New Way to Color Textiles with Colorifix's Orr Yarkoni

    In this replay episode of Grow Everything, Karl and Erum catch up after recent travel, reflect on a standout mainstream biotech article about biology reshaping the global chemical industry, and discuss why “tissue-on-a-chip” experiments in space matter for long-duration missions. They then kick off a deeper dive into bio-based dyes by revisiting their interview with Orr Yarkoni, co-founder and CEO of Colorifix, who explains how engineered microbes can both produce and directly deposit pigment onto textiles to dramatically reduce toxic chemistry, water use, and energy demand compared to conventional dyeing. The conversation covers why black and high-performance reds remain the hardest colors to replace, how Colorifix approaches scale-up through distributed on-site fermentation hardware, and what it takes to meet the real-world fastness and safety standards that brands and mills require. Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing? Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters: (00:00:00) Travel catch-up and what the hosts have been thinking about lately(00:05:30) Mainstream biotech gets it right: biology as “Mother Nature’s R&D lab” for the chemical industry(00:07:15) Artemis and why deep-space biology experiments matter(00:08:40) Project Hail Mary and communicating across radically different biology(00:12:55) Why this season is focusing on bio dyes, and why textiles are a key wedge industry(00:16:55) Interview begins: Orr’s background and the pivot from arsenic biosensing to dyeing(00:20:15) How conventional textile dyeing works, and why it is so chemically and water intensive(00:24:10) What Colorifix does differently: microbes that make dye and fix it onto fabric(00:27:10) Performance realities: lightfastness, washfastness, and why “green but fragile” is not sustainability(00:29:35) Finding pigments in nature, choosing the right biosynthetic routes, and translating them across materials(00:34:20) Who buys what: dye houses, mills, and how the business model works(00:36:55) Scaling fermentation the hard way: standardizing hardware and enabling on-site production(00:40:05) Hardware basics and the economics of bioreactors for commodity chemicals(00:44:05) Worker health, safer chemistry, and toxicity testing across the full process(00:46:05) Where you can find Colorifix in-market, and which materials are trending(00:49:00) Color priorities: why blue is easiest, and why black is the biggest challenge(00:51:15) Regulation tailwinds: why some black chemistries are being phased out(00:55:15) The future: bio-manufacturing everyday goods at scale(00:58:45) Orr’s film recommendation: The Man in the White Suit(01:00:00) Closing: upcoming live recording at DC Climate Week and SynBioBetaLinks and Resources: Colorifix 75. Dye Another Day: The New Way to Color Textiles with Colorifix's Orr YarkoniTracking the removal of Petroleum-based Food Dyes Food Safety and Health Concerns of Synthetic Food DyesNational Geographic Spider SilkArtemis Mission - Lunar FlybyDC Climate WeekSynBioBeta Pass - Discount code: Grow Everything Topics Covered: industrial biotech, synthetic biology, biomanufacturing, microbial fermentation, engineered microbes, sustainable textiles, bio-based dyes, textile dyeing process, green chemistry Have a question or comment? Message us here: Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠ Music by: Nihilore  Production by: Amplafy Media

    1h 3m
  8. Apr 10

    176. Dare to Commercialize: Damien Perriman’s eXoZymes Playbook

    Damien Perriman, Chief Commercial Officer of eXoZymes and the commercial lead behind the NCTx spinout, breaks down why cell-free biomanufacturing changes the rules for scaling nature’s rare molecules. Damien explains why the team spun NCTX out as a separate commercial vehicle, what it means to successfully transfer a process to a partner manufacturer (including a milestone Cayman validation), and why NCT (n-trans-caffeoyl tyramine), a trace compound found in peppercorns and hemp seed husks, has drawn so much attention as the only known agonist of HNF4A, a metabolic “switch” tied to mitochondrial function. The conversation also covers the logic behind launching first in supplements, how to build credibility in a crowded category through safety and product consistency, how regulatory timelines shape strategy, and why industrial biotech needs to move from platform-first stories to molecule-led business cases that match real market demand. Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing? Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters: (00:00:00) Welcome, introductions, and why tech transfer matters(00:02:10) Why eXoZymes spun out NCTX to commercialize faster(00:03:30) Cayman scale-up milestone: 99% conversion and 99.6% purity(00:05:20) What the Cayman validation proves for product delivery and partners(00:08:10) Why launch NCT in supplements first, and what GRAS enables(00:10:00) Building credibility in supplements: safety, purity, and consistency(00:12:05) What HNF4A is, and why NCT is the only known agonist(00:14:30) What’s next: more human use studies, dose regimens, and GLP-1 adjacencies(00:16:00) NCT vs GLP-1s: “metabolic restoration” and where it might fit(00:18:10) “Natural” vs safe and effective: what really matters(00:21:00) Examples of trace natural molecules scaled for human use(00:22:30) GRAS + FDA timelines: how they’re navigating regulatory reality(00:26:00) The Molecule Manifesto: why industrial biotech needs molecule-led business cases(00:31:00) How eXoZymes chooses what to work on (idea management system)(00:33:00) Vision: what success looks like in 5–10 years(00:35:00) Quickfire: NCT in ice cream, NCT as “WALL-E,” and other rapid takes(00:38:10) What people misunderstand about cell-free biomanufacturing(00:40:00) Wrap-up + post-episode reflectionLinks and Resources: eXoZymesInterview: Cayman Chemical validates eXoZymes' technology and scalabilityeXoZymes’ Cell-Free Biomanufacturing Platform Gets Positive Feedback from Cayman ChemicaleXoZymes on LinkedInDamien Perriman - new CCO129. No Cells? No Problem! eXoZymes' Michael Heltzen on the Future of Microbe-Free Biotech29. Gut Check with Stephanie Culler: Persephone’s Quest for Microbiome Breakthroughs170. There's a Bug for That: Sophia Xu on CarbonBridge's Notebook Bioreactors166. The Great Reformulation: Joshua Lachter Rethinks How We Make Everything at ScaleTopics Covered: cell-free biomanufacturing, industrial biotech, NCTx, HNF4A, metabolic switch, tech transfer, CDMO, supplements vs pharma, GRAS, purity and consistency Have a question or comment? Message us here: Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠ Music by: Nihilore  Production by: Amplafy Media

    46 min
4.9
out of 5
21 Ratings

About

Grow Everything explores the world of biology as technology. Hosts Erum Khan and Karl Schmieder interview leaders and influencers biologizing industries with tools like synthetic biology, precision fermentation, bioprospecting, and more. These companies make biomaterials from waste, cosmetics that restore healthy hair and skin, and delicious cultivated foods in a bioreactor and so much more. Join us as we discuss the latest and greatest across biotech, engineered biology, entrepreneurship, and culture and how this transition is solving healthcare and climate change challenges.

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