Giant Ideas

Giant Ventures
  • 5.0 (4)
  • Entrepreneurship
  • Updated Biweekly

Giant Ideas invites leading minds from tech, business, politics, and beyond to explore the giant ideas changing our world. Giant Ventures, founded by Cameron McLain and Tommy Stadlen, backs purpose-driven founders shaping civilisation.

  1. 3d ago ·  Video

    Isomorphic Labs President Max Jaderberg: Can AI Solve All Disease?

    Today, we're joined by Max Jaderberg, President of Isomorphic Labs. Isomorphic Labs, the Alphabet-backed company spun out of DeepMind, is using AI to design new medicines, with the mission of solving all disease.  Tommy Stadlen and Cameron McLain talk to Max about why he believes no future exists where medicines aren't designed with AI, and why he'd be "severely disappointed" if disease doesn't mean something completely different 30 years from now. He speaks about: What "solve all disease" means in practice How a medicine actually gets made today, and why it's "very, very fancy trial and error"Why earlier AI drug discovery overpromised, and what AlphaFold changedWhy you can't download the data this field needs off the internetThe 90% clinical failure rate Bio-resilience, bad actors, and why Isomorphic keeps its models in-houseBuilding a purpose driven company? Read more about Giant Ventures at www.Giant.vc. Music credits: Bubble King written and produced by Cameron McLain and Stevan Cablayan aka Vector_XING. Please note: The content of this podcast is for informational and entertainment purposes only. It should not be considered financial, legal, or investment advice. Always consult a licensed professional before making any investment decisions.

    Isomorphic Labs President Max Jaderberg: Can AI Solve All Disease?

  2. Oct 1 ·  Video

    What Traits Do the BEST Founders Share? Tommy & Cameron's Reflections

    After more than 50 episodes interviewing founders, investors and leaders, Giant co-founders Tommy Stadlen and Cameron McLain turn the mic on themselves to ask what the best entrepreneurs have in common. From resilience, storytelling, obsession and self-awareness, to the power of control. They speak about: Cameron's four founder traits, and why three out of four is the barWhy Tommy added control to his list (and what Alex Ferguson has to do with it)Producing under fire vs simply enduringThe case for benign dictatorship in early-stage companies"Trauma showcasing" in pitch meetings, and what drives foundersThe four burners: what founders give up, and why the greats might not call it sacrificeWhy intelligence might not make the top threeAgentic founders, 16-year-olds pitching from Sweden and 10-person teams building huge revenue...Building a purpose driven company? Read more about Giant Ventures at www.Giant.vc. Music credits: Bubble King written and produced by Cameron McLain and Stevan Cablayan aka Vector_XING. Please note: The content of this podcast is for informational and entertainment purposes only. It should not be considered financial, legal, or investment advice. Always consult a licensed professional before making any investment decisions.

  3. Sep 24 ·  Video

    AOL Co-founder, Steve Case: AI Lessons from the Internet Boom

    Today, we're joined by Steve Case, the co-founder of AOL, to talk about what the first internet boom can tell us about this one. Steve started AOL in 1985, when 3% of people were online. He took it public in 1992 as the first internet company to list, and now runs Revolution, the firm behind Rise of the Rest and more than 200 investments across 100 American cities.  Cameron McLain talks to Steve about why AOL raised just $10 million over seven years (while today's AI companies are seeded with a billion), why he still thinks the Time Warner merger was the right call, and why he thinks AI needs to be very carefully deployed to avoid a revolution. He speaks about: The nine years it took AOL to reach a million users (ChatGPT took three months)Arguing with IBM and Apple about whether to build modems into computersBeing 26 and taking on AT&T, GE and Microsoft with just $10 millionWhether he'd do the Time Warner merger againThe industries AI can't disruptBuilding a purpose driven company? Read more about Giant Ventures at www.Giant.vc. Music credits: Bubble King written and produced by Cameron McLain and Stevan Cablayan aka Vector_XING. Please note: The content of this podcast is for informational and entertainment purposes only. It should not be considered financial, legal, or investment advice. Always consult a licensed professional before making any investment decisions.

    AOL Co-founder, Steve Case: AI Lessons from the Internet Boom

  4. Sep 17 ·  Video

    Does "Financial Gravity" Corrupt? - Lean Startup author Eric Ries on staying Incorruptible

    Today, we're joined by Eric Ries, the author of The Lean Startup and the founder of the Long-Term Stock Exchange. Eric wrote the book that taught a generation of founders how to build under uncertainty, and he has spent the years since trying to fix what happens to those companies once they grow. His new book, Incorruptible, is about a double mystery: why successful companies so often get ruined, and why a handful avoid that fate. Tommy Stadlen and Cameron McLain talk to Eric about why he thinks the best practices of modern corporate governance destroy value, why he believes a strong founder is not enough to protect a company, and what he'd change about The Lean Startup if he could go back. Building a purpose driven company? Read more about Giant Ventures at www.Giant.vc. Music credits: Bubble King written and produced by Cameron McLain and Stevan Cablayan aka Vector_XING. Please note: The content of this podcast is for informational and entertainment purposes only. It should not be considered financial, legal, or investment advice. Always consult a licensed professional before making any investment decisions.

    Does "Financial Gravity" Corrupt? - Lean Startup author Eric Ries on staying Incorruptible

  5. Sep 10

    Ex-Sequoia Chair, Michael Moritz - on Modern America & His New Book Ausländer

    Today, we're back with Michael Moritz, the Sequoia investor who backed Google, Yahoo and PayPal, to talk about his family and his latest book. Moritz has written a memoir, Ausländer, out in the US this month. It began with papers found when they cleared out their mother's house in Wales, and grew into an account of how his grandparents were murdered and how his father got out during the Nazi Regime. We talk to him about what he found in the archives, why he thinks a stable society is a much more fragile thing than most people assume, his experience of anti-semitism, and if he thinks Silicon Valley is befriending Trump (and what he thinks of the US president). Building a purpose driven company? Read more about Giant Ventures at www.Giant.vc. Music credits: Bubble King written and produced by Cameron McLain and Stevan Cablayan aka Vector_XING. Please note: The content of this podcast is for informational and entertainment purposes only. It should not be considered financial, legal, or investment advice. Always consult a licensed professional before making any investment decisions.

    Ex-Sequoia Chair, Michael Moritz - on Modern America & His New Book Ausländer

  6. Sep 3

    Former Sequoia Chair Michael Moritz on Assessing Founders: "It's All About the First 15 or 16 Years of Life"

    Today, we're joined by Michael Moritz, the former chairman of Sequoia Capital, one of the most successful venture capitalists of all time. Michael Moritz is a venture capitalist and philanthropist renowned for backing early tech giants like Google, PayPal, and YouTube during his 38-year career, first as Partner then Chairman of the firm.  Cameron McLain and Tommy Stadlen talk to Michael about why he thinks the first 16 years of a founder's life tell you more than you can find anywhere is, why he still wears the cap of the company that lost Sequoia more money than any other, and why he shivered every time anyone called Sequoia an institution. He speaks about: the phone call that brought Sequoia to Googlewhy he asks founders about their first 15 or 16 yearsmeeting the Collison brothers at 20 and 18, and what was obvious within minuteswhy founding pairs make each other betterwhy Bill Gates took the radio taken out of his Mercedes the $44m Webvan loss, and going back to the same idea 20 years later as Instacartand lots more...Building a purpose driven company? Read more about Giant Ventures at www.Giant.vc. Music credits: Bubble King written and produced by Cameron McLain and Stevan Cablayan aka Vector_XING. Please note: The content of this podcast is for informational and entertainment purposes only. It should not be considered financial, legal, or investment advice. Always consult a licensed professional before making any investment decisions.

    Former Sequoia Chair Michael Moritz on Assessing Founders: "It's All About the First 15 or 16 Years of Life"

  7. Aug 6

    "Run Towards Growth" Career Advice From ex-YC COO and Applied Intuition CEO Qasar Younis

    Today, we're back for our FINAL episode before a 3 week summer break! We're back the first week of September. Today we're joined by Qasar Younis, co-founder and CEO of Applied Intuition and former COO of Y Combinator, to talk about his life lessons & career advice. He speaks about: The rule he got from a Harvard professor: a mediocre person in a high-growth industry beats the best person in a mediocre oneThe most useful advice of his careerOptimising for the people you'll learn from over title and pay (at any cost)The four life-burners problem, and which one he switched offWorking seven days a week since he was 14, and what his routine is on the weekendWhy you can't become Nirvana by copying Kurt CobainThe three eras of Y Combinator, and why the old YC wouldn't work today"We Make Mistakes" — the only post he wrote as COO, and why it mattersBuilding a purpose driven company? Read more about Giant Ventures at www.Giant.vc. Music credits: Bubble King written and produced by Cameron McLain and Stevan Cablayan aka Vector_XING. Please note: The content of this podcast is for informational and entertainment purposes only. It should not be considered financial, legal, or investment advice. Always consult a licensed professional before making any investment decisions.

    "Run Towards Growth" Career Advice From ex-YC COO and Applied Intuition CEO Qasar Younis

  8. Jul 30

    Applied Intuition CEO, Qasar Younis: Why He Raised ~$1B but Never Spent a Dollar

    Today, we're joined by Qasar Younis, co-founder and CEO of Applied Intuition, a physical AI company valued at $15 billion that builds the models and simulation tools behind autonomous vehicles, defence systems, and industrial machines (before this, he was COO of Y Combinator). Tommy Stadlen talks to Qasar about why he thinks physical AI will define the next 25 years, and why Applied's ability to run the same models across cars, drones, and construction equipment is its biggest edge. They also get into how he thinks about fundraising and cap tables, and why he says not all money is equally useful. He speaks about: Why Applied Intuition has never spent a dollar of the ~$1 billion raisedCorporate VCs, multi-stage funds, and why the partner matters more than the firm nameWhy 85% of the global economy is physical (and why that's the real AI opportunity)Neural simulation, and how Applied trains one model to work in a car, a drone, and a tankWhy timing is the hardest thing for founders to get rightWhy he's not worried about self-driving safetyThe billion-machine vision (and why he still drives a 1987 manual Land Cruiser)Enjoy! Building a purpose driven company? Read more about Giant Ventures at www.Giant.vc. Music credits: Bubble King written and produced by Cameron McLain and Stevan Cablayan aka Vector_XING. Please note: The content of this podcast is for informational and entertainment purposes only. It should not be considered financial, legal, or investment advice. Always consult a licensed professional before making any investment decisions. Building a purpose driven company? Read more about Giant Ventures at www.Giant.vc. Music credits: Bubble King written and produced by Cameron McLain and Stevan Cablayan aka Vector_XING. Please note: The content of this podcast is for informational and entertainment purposes only. It should not be considered financial, legal, or investment advice. Always consult a licensed professional before making any investment decisions.

    Applied Intuition CEO, Qasar Younis: Why He Raised ~$1B but Never Spent a Dollar
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Giant Ideas invites leading minds from tech, business, politics, and beyond to explore the giant ideas changing our world. Giant Ventures, founded by Cameron McLain and Tommy Stadlen, backs purpose-driven founders shaping civilisation.

Information

  • Creator
    Giant Ventures
  • Years Active
    2024 - 2026
  • Episodes
    81
  • Rating
    Explicit
  • Copyright
    © 2026 Giant Ideas
  • Show Website
    Giant Ideas

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