Age of Aging

Penn Memory Center

Welcome to the Age of Aging, a podcast about living well with an aging brain. The Age of Aging is a podcast released every other Tuesday, covering a wide range of stories in aging research. Co-hosted by Jake Johnson and Terrence Casey from the Penn Memory Center communications team, each episode they will explore what it means to age with independence and dignity in the modern world. The Age of Aging is recorded and produced at the Michael Naidoff Communications Hub at the Penn Memory Center.

  1. 9h ago

    Dancing Around Dementia

    There are a few things we know can help keep our brains healthy as we age like exercise, social connection, learning a new skill, and creative expression. One activity combines all of these, but it might also bring back memories of early childhood embarrassment. In this episode, we explore dance as a tool for healthy aging, and why it may be one of the best things we can do for longevity.   Inside this episode  0:49 – Ballet at Any Age   Dr. Jason Karlawish explains why he began taking Vaganova ballet as an adult and the mental benefits he’s experienced.  4:11 – A Childhood Dance Disaster  Carolyn Hewson recounts her brief and traumatic first experience performing ballet and why she spent decades avoiding dance.  8:09 – The Dementia Prevention Dance Club  After experiencing the physical, cognitive, and social benefits of learning choreography, Carolyn and her fellow moms launch a monthly dance group.   9:40 – What Sets Dance Apart from Other Exercise  Dr. Julia Basso explains how dance engages multiple brain systems at once through movement, memory, rhythm, emotion, creativity, and social connection.  13:27 – Dance Movement Therapy  Dance movement therapist Natasha Goldstein-Levitis explains how therapeutic movement helps people living with dementia connect emotionally, physically, and socially.  17:05 – Dance for Parkinson's Disease  David Leventhal shares the origin story of Dance for PD, a program that began with six participants and grew into an internationally recognized model for movement and community.  20:27 – A Passion for Movement   Emily and Judy Tobey reflect on how Dance for PD became a vital source of physical activity, friendship, and purpose for their husband and father, Charlie.  24:54 – We Are Born to Dance  David Leventhal argues that dance is a fundamental part of human expression and that anyone can benefit, regardless of experience or ability.  29:34 – “There’s No Ceiling”  Dr. Karlawish discusses his favorite aspects of learning dance, including the social connection, the focus it brings him, and the chance to practice something with limitless offerings     Resources available on the episode webpage linked below  Read more about Dr. Julia Basso's Embodied Brain Lab at Virginia Tech.  Explore EngAge from Natasha Goldstein-Levitas.  Learn more about Dance for PD and classes available through the Mark Morris Dance Group.  Watch the documentary Capturing Grace, featuring participants from the Dance for PD program, including Charlie Tobey.  Learn more about the Tango Therapy Project.  Learn about the Time Dances program, a new dance initiative for people living with dementia developed by Dance for PD and TimeSlips.  Book private ballet lessons with Amy Novinski Take adult classes at Philadelphia Ballet. Special thanks to Carolyn Hewson, Dr. Julia Basso, Natasha Goldstein-Levitas, David Leventhal, Emily Tobey, Judy Tobey, Neil Godik, and today's hosts, Dr. Jason Karlawish and J...

  2. Oct 6

    Lonely Minds

    At The Age of Aging, we often talk about the importance of physical activity and a healthy diet for brain longevity. However, one of the best things you can do to promote brain health as you age may also seem unlikely: hanging out with your friends.   In this episode, we explore the growing body of research linking social isolation and loneliness to cognitive decline and dementia risk. We’ll hear from older adults navigating loneliness, researchers studying its effects on the brain, and members of a unique housing community designed to help older adults stay connected.  Later, Terrence Casey, Jake Johnson, and Executive Producer Dr. Jason Karlawish reflect on what loneliness looks like in clinical practice, why social isolation can complicate dementia diagnosis and care, and what listeners can do to build stronger social connections throughout their lives.  Inside this episode  5:35 – Social Isolation and Brain Health  Dr. Holly Elser explains why social isolation is considered one of the 14 modifiable dementia risk factors and how social connection may help build cognitive reserve.  7:43 – The Dementia Risk of Isolation  Dr. Barbara Sahakian discusses research from the UK Biobank showing that socially isolated adults had a 26% increased risk of developing dementia.  11:13 – Grief, Purpose, and Feeling Alone  Frank Saar reflects on life after the death of his wife and the challenge of rebuilding a sense of purpose while coping with loneliness.  15:24 – A Community Built for Connection  Residents and staff from Morningside Gardens in New York describe how a Naturally Occurring Retirement Community (NORC) helps older adults stay socially engaged, active, and supported.  18:13 – The Social Lives of Healthy Agers  Philadelphia artist Jean Lindsay shares how decades of participation in community arts programs helped him build friendships and maintain a sense of purpose.  21:40 – “It’s Okay to Ask for Help”  Doris Kitt explains why loneliness is deeply personal and why older adults should seek support when isolation begins to affect their well-being.  24:39 – What Loneliness Looks Like in the Clinic  Jason Karlawish discusses how social isolation often appears early in dementia and why clinicians pay close attention to changes in a person's daily routines and social engagement.  34:13 – Finding Your Community Before You Need It  Jake and Jason discuss why building meaningful social connections earlier in life may be one of the most powerful investments people can make in their long-term brain health.    Resources available on the episode webpage linked below  Check out the 2024 Lancet Commission on Dementia Prevention, Intervention, and Care infographic outlining the 14 modifiable risk factors for dementia.  More on Barbara Sahakian  Read Dr. Sahakian’s book, Brain Boost  Learn more about Morningside Gardens Retirement and Health Services   Learn more about Naturally Occurring Retirement Communities   Sign up for a class at Fleisher Art Memorial Resources for older adults experiencing loneliness and social isol...

  3. Sep 22

    Daughter, Doctor, or Both?

    At the Age of Aging, we often speak with researchers and clinicians who have devoted their careers to understanding dementia and caring for the people living with it. Less often, we hear what happens when dementia becomes personal for those same experts.  In this episode, neuropsychologist Dr. Emma Rhodes shares her experience caring for her father, Jack, following his diagnosis of dementia due to Alzheimer's disease. In conversation with Penn Memory Center Director of Social Work Allison Lynn, Emma reflects on grief, stigma, caregiving, and the challenges of navigating life as both a dementia expert and a daughter. Then, Executive Producer Dr. Jason Karlawish and Editorial Director Terrence Casey unpack some of the interview's most powerful moments, connecting Emma's experience to broader lessons about caregiving and dementia care.  Inside this episode  4:18 – Daughter First, Neuropsychologist Second: Emma Rhodes reflects on the challenge of balancing her professional knowledge with the emotional reality of caring for her father.  7:52 – The Uncanny and Ambiguous Loss: Jason Karlawish discusses the profound grief family caregivers experience when a loved one is simultaneously familiar and changed by dementia.  12:45 – When Professional Calm Breaks Down: Jason shares a candid story about losing his composure while trying to help his father manage his finances.  16:03 – Dementia Stigma Firsthand: Emma describes how caring for her father revealed just how difficult and often unwelcoming the world can be for people living with cognitive impairment.  19:48 – Clinicians as Caregivers: Jason and Terrence explore why more healthcare professionals are speaking openly about their personal experiences with dementia in their own families.  28:15 – The Hidden Work of Caregiving: Emma discusses the emotional, logistical, and physical effort required to attend clinic visits, participate in research, and manage day-to-day care.  32:48 – “How Are You Doing?” Jason explains why one of the most important questions a clinician can ask a caregiver is also one of the simplest.  39:26 – “Our Families Are Your Patients Too”: Jason reflects on why healthcare systems must better recognize and support family caregivers as essential partners in dementia care.  Resources available on the episode webpage linked below  Watch the full interview with Dr. Emma Rhodes and Allison Lynn on the Penn Memory Center YouTube channel  Find caregiver support groups through Penn Memory Center   Explore Medicare's GUIDE program  Special thanks to Emma Rhodes, PhD, Allison Lynn, LCSW as well as today's co-hosts, Terrence Casey and Jason Karlawish, MD.  The Age of Aging is a Penn Memory Center production hosted by Producer Jake Johnson and Executive Producer Jason Karlawish. Contributors include Morgann Adams, Terrence Casey, Dalia Elsaid, Emily Largent, and Allison Lynn.  The Age of Aging is made possible by generous support from the Michael Naidoff Communications Hub Fund and Lena Chow.

  4. Sep 8

    Deconstructing Home

    What makes a house a home? And what happens when that home no longer works for the person living in it? In this episode, we explore the emotional and practical challenges of downsizing and moving later in life — from letting go of decades of possessions to navigating dementia, family dynamics, and the fear of what comes next.  Inside this episode:  1:06 – Deconstructing Home: Dr. Jason Karlawish explores what makes a home more than just four walls and why dementia can change the way someone experiences their environment.  8:24 – Professional Downsizers: Move managers Susan Blumenfeld and Charlotte Schutzman explain the emotional and logistical challenges of helping older adults decide what stays, what goes, and what their possessions are really worth.  13:19 – 10x Harder: Kristi Mabe shares what it was like to move her own mother into assisted living, and why helping a family member can be much harder than helping a client.  20:56 – “It’s the People, It’s Not the Place”: Mary Ellen Weber shares how moving to a retirement community helped her and her husband find connection, independence, and a richer daily life.  25:00 – Tied to the Mast of Aging in Place: Dr. Karlawish discusses the risks of being too committed to living in one place when a home becomes isolating or no longer meets someone’s needs.  36:36 – Coming Home: Jake and Dr. Karlawish turn to The Odyssey to consider what really makes a place home.  Resources available on the episode webpage linked below  Learn more about New Roots Move Management  Learn more about All Moving Matters  Find a local move management company   Special thanks this episode to Kristi Mabe, Charlotte Schutzman, Susan Blumenfeld, and Mary Ellen Weber, as well as today’s co-host, Jason Karlawish, MD.  The Age of Aging is a Penn Memory Center production hosted by Producer Jake Johnson and Executive Producer Jason Karlawish. Contributors include Morgann Adams, Terrence Casey, Dalia Elsaid, Emily Largent, and Allison Lynn.  The Age of Aging is made possible by generous support from the Michael Naidoff Communications Hub Fund.

  5. Aug 26 ·  Bonus

    This Moment in Alzheimer's 2026

    Welcome to our annual summer bonus episode of the Age of Aging, where our Penn Memory Center experts reflect on the latest research from the annual Alzheimer’s Association International Conference (AAIC). On today’s episode, Age of Aging Executive Producer and PMC Co-Director Dr. Jason Karlawish sat down with Co-Director Dr. David Wolk and Dr. Chris Brown to unpack their biggest takeaways from their time in London. They discuss everything from new blood-based biomarkers to the latest data on anti-amyloid and tau-targeting therapies as well as what the future of Alzheimer’s treatment may look like.   The Age of Aging will return for Season 6 in September, so please make sure you’re subscribed wherever you get your podcasts, and we’ll see you soon.   Inside this episode:  2:40 – How AAIC Has Changed: The group compares this year's meeting to AAIC 2017 and discusses how the science has shifted to a more clinical focus.  9:26 – Predicting Brain Health: Dr. Brown and Dr. Wolk discuss where p-tau 217 stands as a biomarker as well as new markers like neuronal pentraxin (NPTX) for measuring synaptic health beyond amyloid and tau.   22:42 – The Blood-Brain Barrier: The clinicians provide an update on the two anti-amyloid therapies currently available as well as discuss the brain "shuttle" technology, which appears to significantly improve amyloid clearance and safety.  29:59 – Tau has its Moment: Results from the CELIA antisense oligonucleotide study show a "Goldilocks dose" effect, plus a look at a negative Lilly tau-lowering trial.   35:25 – Closing Highlights & What’s Next: Jason spotlights the LiBBY study, testing a THC/CBD combination for agitation in advanced dementia, before the group previews next year's AAIC 2027 meeting in Chicago.    Resources available on the episode webpage linked below   Learn more about the Alzheimer’s Association and AAIC  Study: "Predicting Risk of Cognitive Impairment With Alzheimer Disease Blood Biomarkers” (JAMA)  Study: “Clinicopathologic Evaluation of Amyloid Clearance in Alzheimer Disease” (JAMA)  “Amyloid removal may reduce tau buildup and neurodegeneration in Alzheimer’s disease” (Penn Medicine)  Press release on Phase 2 of the CELIA Study  Press release on LiBBY Trial  Special thanks this episode to Jason Karlawish, MD, David Wolk, MD, and Christopher Brown, MD, PhD.  If this episode, or another episode, has resonated with you, please subscribe, leave us a review, or share it with somebody who would appreciate it. This makes a real difference in helping others find the show. And if you have a topic you’d like to hear, email us at hello@ageofaging.org.  The Age of Aging is a Penn Memory Center production, hosted by Editorial Director Terrence Casey and Producer Jake Johnson. Contributors include Morgann Adams, Dalia Elsaid, Jason Karlawish, Emily Largent, Alison Lynn, and Mischa Norton.   The show is made possible by generous support from the Michael Naidoff Communications Hub Fund and Lena Chow.

  6. Jul 14 ·  Bonus

    Dancing in the Rain

    At the Age of Aging, we are sometimes lucky enough to have too many great stories to fit into a single podcast episode. We ran into this fortunate circumstance last season with our episode, “Ambiguous Loss,” which shared the stories of two caregivers grappling with their loved one’s decline from dementia. On today's mid-summer bonus episode, we share a third story we recorded that didn’t make the cut – not because it wasn't good enough, but because it was too complete to be a piece of something else.   Margo Woodacre is an author, teacher, former state senator, and for eight years, the primary caregiver for her husband, Ernie, who was living with Alzheimer's. In this standalone conversation, Woodacre reflects on caregiving, grief, identity, and the slow work of asking, “Who am I now?” that followed the loss of Ernie.    Inside this episode:  2:02 – Becoming a Caregiver: Woodacre reflects on the early signs of Ernie’s Alzheimer’s disease, the fear that followed his diagnosis, and the emotional challenge of caring for someone whose personality was beginning to change.  6:18 – Learning to Dance in the Rain: After a difficult moment in Ernie’s illness, Woodacre shares how a neighbor’s advice helped her reframe caregiving, change her own responses, and meet Ernie where he was. In doing so, she learned how to reduce conflict, preserve connection, and keep finding meaningful moments with him.  10:26 – Delayed Grief: Woodacre reflects on the surprising sense of relief that followed Ernie’s passing, the administrative work of closing a life, and the delayed grief that emerged once the busyness faded.  13:49 – Losing and Reclaiming Identity: After years of caregiving, Woodacre found herself asking who she was without Ernie and without the caregiving role that had shaped her daily life. She discusses journaling, meditation, teaching, politics, support groups, and solo travel as part of her path back to herself.  16:20 – Traveling Alone Again: Woodacre shares the story of her first solo trip after Ernie’s death, a dude ranch vacation that began in loneliness and became a turning point in rebuilding confidence, openness, and independence.  19:08 – Advice for Grieving Caregivers: Woodacre offers guidance for people beginning the grieving process: take your time, allow yourself to grieve, but don’t stay so long in pain that you miss the next lesson life may still have to offer.    Resources available on the episode webpage linked below   Learn more about Margo Woodacre  Read more about Woodacre’s essay, “Journey Back to Self: Life After Caregiving,” on Making Sense of Alzheimer’s  Read Woodacre’s previous book, I’ll Miss You Too: The Off-to-College Guide for Parents and Students  Learn more about Woodacre’s forthcoming book, Crossroads: Reclaiming Identity When Life Changes Everything, scheduled for release in early fall  Special thanks this episode to Margot Woodacre for sharing her story with us.  If this episode, or another episode, has resonated with you, please subscribe, leave us a review, or share it with somebody who would appreciate it. This makes a real difference in helping others find the show. And if you have a topic you’d like to hear, email us at hello@ageofaging.org.  The Age of Aging is a Penn Memory Center production, hosted by Editorial Director Terrence Casey and Producer Jake Johnson. Contributors include Dalia Elsaid, Jason Karlawish, Emily Largent, Alis...

  7. Jun 16

    The Stories We Tell

    At The Age of Aging, we know that the stories we tell about dementia shape the perceptions, resources, and, ultimately, the lived experience of people with the condition. As such, it is our number one priority to understand what narratives serve an aging population and which ones are better left in the past.   For the Season 5 finale, our team reflects on a special report from Hastings Center for Bioethics, Living with Dementia: Learning from Cultural Narratives of Aging Societies. Through a series of personal audio essays, some familiar voices from this season explore how cultural narratives influence the lived experience of dementia—and how new stories might help us build a more compassionate, creative, and supportive future.  Inside this episode:  4:21 – Managing Dependence: Dr. Jason Karlawish discusses Mercer Gary's essay on assistive technologies in dementia care. He explores the tension between fears of technological dependence and hopes that technology can eliminate dependence altogether.  11:47 – Creativity, Collaboration, and Dementia: Terrence Casey, editorial director and co-host of The Age of Aging, reflects on Julia Henderson's essay examining participatory arts programs and how projects like Anne Basting's Penelope Project challenge conventional narratives about dementia.  16:19 – Learning from History: Dr. Emily Largent discusses Jesse Ballenger's essay on the history of dementia. She explores how modern anxieties about cognitive decline are shaped by changing ideas about identity, aging, and selfhood.  20:15 – New Narratives for a More Just Future: Producer and Co-Host Jake Johnson examines how cultural narratives influence dementia care and why imagining ourselves into the lives of people living with dementia and caregivers is essential to meaningful social change.  25:34 – Rethinking Housing and Care: Dr. Holly Elser discusses supportive housing as a promising model for people living with dementia, offering an alternative to the traditional divide between aging in place and institutional care.  28:14 – Season 5 Reflections: Dr. Jason Karlawish, Jake Johnson, and Terrence Casey discuss their favorite episodes from the season, lessons learned from reporting on aging and dementia, and what listeners can expect this summer and in Season 6.  Resources available on the episode webpage linked below  Use offer code “AGING” to get 50% off your copy of Dementia Care’s Radical New Era  Read the essays featured in the special report, Living with Dementia: Learning from Cultural Narratives of Aging Societies from the Hastings Center for Bioethics  Read the Pope Leo’s Magnifica Humanitas: On Safeguarding the Human Person in the Time of Artificial Intelligence  Learn more about Anne Basting’s Penelope Project  Explore Penn Memory Center creative engagement programs  Special thanks this episode to Jason Karlawish, MD, Emily Largent, PhD, JD, RN, Jake Johnson, and Holly Elser, MD, PhD, MPH.  The Age of Aging is a Penn Memory Center production, hosted by Editorial Director Terrence Casey and Producer Jake Johnson. Contributors include Dalia El Said, Jason Karlawish, Emily Largent, Alison Lynnn, and Morgann Adams.  The show is made possible by generous support from the Michael Naidoff Communications Hub Fund and Lena Chao.  Caring for an aging loved...

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About

Welcome to the Age of Aging, a podcast about living well with an aging brain. The Age of Aging is a podcast released every other Tuesday, covering a wide range of stories in aging research. Co-hosted by Jake Johnson and Terrence Casey from the Penn Memory Center communications team, each episode they will explore what it means to age with independence and dignity in the modern world. The Age of Aging is recorded and produced at the Michael Naidoff Communications Hub at the Penn Memory Center.

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