Send us Fan Mail If you're taking a GLP-1, you've probably heard plenty about protein and strength training. Where does creatine fit, and what does it mean if the scale rises after you start taking it? Ana Reisdorf talks with Kristin Kirkpatrick about muscle health, the practical choices involved in taking creatine, and what the research can and cannot yet tell us about benefits beyond the gym. Kristin explains how creatine works alongside resistance training, why a loading phase may not be necessary, and what to consider when choosing a form. She and Ana also discuss bloating, water retention, early research on brain health, and whether you can build muscle after starting a GLP-1. **IN THIS EPISODE** - What creatine does in the body and why it comes up in the muscle-health conversation - How creatine, protein, and resistance training fit together during GLP-1 weight loss - What emerging research suggests about brain health and what it does not establish - Creatine monohydrate, HCl, powders, and gummies: questions to consider when choosing a product - Loading phases, dose, and timing, and why individual needs vary - Water retention, bloating, and why a change on the scale may not mean fat gain - Building strength and muscle after starting a GLP-1 **ABOUT THE GUEST** Kristin Kirkpatrick, MS, RD, is a registered dietitian at Cleveland Clinic and president of KAK Consulting, LLC. She has worked in nutrition and integrative care for more than 20 years, contributes to TODAY.com, and co-authored Skinny Liver and Regenerative Health with gastroenterologist Ibrahim Hanouneh, MD. **CONNECT WITH KRISTIN** Website: https://www.kristinkirkpatrick.com/ Instagram: https://www.instagram.com/fuelwellwithkrissy/ **SPONSOR** Tyde Wellness offers GLP-1 care with licensed providers, nutrition guidance, and ongoing support. Use code GLP1Hub50 for $50 off your first month. https://tydewellness.com/GLP1Hub Velogenix's Project Aeterna offers a free at-home mobility baseline and Pro assessments of strength, balance, and gait. Use code OFF for $50 off your first year of Pro. https://velogenix.com **CHAPTERS** 00:00 Why creatine is getting attention beyond the gym 01:30 Meet Kristin Kirkpatrick 03:22 Kristin's approach to integrative nutrition 06:09 What creatine does in the body 08:05 Creatine myths: Is it just for bodybuilders? 09:09 What the brain-health research can and cannot tell us 12:03 Creatine, strength training, and GLP-1 muscle health 15:13 Sponsor: Tyde Wellness 16:39 Monohydrate vs. HCl, dose, and timing 19:29 Gummies, powder, and the coffee question 23:24 Water retention, side effects, and the scale 26:07 Do you need a loading phase? 28:11 Sponsor: Velogenix 29:14 Muscle, mobility, and healthy aging 31:55 Can you build muscle after starting a GLP-1? 32:58 Connect with Kristin MORE FROM GLP-1 HUB 📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com 🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show. 🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com 📷 Follow on Instagram: @glp1hub 📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub *Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show. *The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.