Demystifying PANS/PANDAS Podcast

Nancy O'Hara MD

Welcome to the Demystifying PANS/PANDAS Podcast with Dr. Nancy O'Hara! Ever wondered why some kids experience sudden, life-altering behavioral changes? This podcast delves into PANS (Pediatric Acute-onset Neuropsychiatric Syndrome) and PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Strep). Experts explore the triggers, symptoms, and innovative treatments for these autoimmune disorders, blending science and heartfelt guidance. From strep to Lyme, natural therapies, emotional support, and recovery stories—this is your guide to hope and healing.

  1. 3h ago

    The Tick-Borne Infections Hiding Behind Your Child's PANS/PANDAS

    In this episode, I wanted to demystify something that gets missed far too often: the role that tick-borne and vector-borne infections can play in a child's PANS or PANDAS. Dr. Casey Kelley and I talk through why most families never remember a tick bite, and how other carriers like fleas, lice, mosquitoes, and pets mean a clean history does not rule infection out. We walk through the symptom patterns that may raise a flag, the honest limits of testing (antibody tests can read falsely negative in the sickest kids), and why she sometimes weighs empiric, clinician-guided treatment by asking a simple question: what would we do differently with the result? She shares how she treats children like small adults with kid-sized doses, opens detox pathways before antimicrobials to ease reactions, and leans on foundations most parents can start with: sleep, anti-inflammatory food, nervous-system and vagal support, Epsom baths, and time. This is not a quick fix, and I never want a parent to leave feeling more afraid. Dr. Kelley's own reminder stayed with me: create joy, even if it's just being silly and dancing in the kitchen. That counts. It is treatable. It does exist. And it takes a village. - - - - - About the Guest: Dr. Casey Kelley is the founder and medical director of Case Integrative Health in Chicago, where she practices integrative and functional medicine with a focus on complex chronic illness, including tick-borne and vector-borne disease. She earned her medical degree at The Ohio State University College of Medicine, has been a member of the Institute for Functional Medicine for more than 15 years, and is a former board member of ILADS. She also teaches clinicians and patients through her Groundwork for Healing course. - - - - - Social Handles: Website: https://caseintegrativehealth.com Groundwork for Healing: https://healwithcase.com - - - - - Nancy O’Hara, MD, MPH, FAAP, FMAPS Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.drohara.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/drnancyohara/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/nhoharamd/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/nancy-o-hara-md-mph-faap-390781258/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Join our listeners on ⁠⁠⁠⁠⁠⁠⁠⁠⁠Spotify⁠⁠⁠⁠⁠⁠⁠⁠⁠, ⁠⁠⁠⁠⁠⁠⁠⁠⁠Apple Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠, and ⁠⁠⁠⁠⁠⁠⁠⁠⁠iHeart Radio⁠⁠⁠⁠⁠⁠⁠⁠⁠. - - - - - PODCAST Thank you for listening. Please subscribe and share. This podcast is produced by DrTalks.com https://drtalks.com/podcast-service/

  2. Jul 29

    Why Chasing One Toxin Rarely Fixes a Complex Kid

    I recorded this one with Dr. Eric Gordon and Dr. Nafysa Parpia at the MAPS conference, right after the two of them gave an incredible lecture on the toxic world we live in, and it is exactly the kind of conversation I wish more families could hear when they feel stuck. So often the search is for the single toxin, the one test, the one thing to remove, and together they gently take that apart. Their view is that it is the total load that matters: a child’s genes, their gut, their nutrient status, and their environment, all interacting. I learn in pictures, and the one that stayed with me is the reminder to go back through the door, not the window, meaning support the body before you try to pull anything out of it. Dr. Gordon takes us through some of the toxicants that get overlooked, aluminum in particular, and why inflammation, the cell danger response, and “root compensations” mean removing a root cause is rarely the whole story. Dr. Parpia walks us through testing wisely, screening before provoking, reading blood versus urine, and checking methylation and minerals before any detox, and both of them keep coming back to why complex chronic illness is an “N of one,” different in every child. None of this is a quick fix, and they are honest that it takes time and does not help everyone. But there is real hope in treating the whole child instead of chasing one number, and that is the note I want families to leave on. It is treatable, it does exist, and it takes a village. Be present, be hopeful. - - - - - About the Guest: Dr. Eric Gordon is the founder and medical director of Gordon Medical, where he focuses on complex chronic illness, patients dealing with persistent infections, toxic exposures, and the kind of layered, hard-to-untangle presentations that other clinics often cannot place. Patients come to him from across the country and beyond. His work centers on treating the whole person rather than a single lab value, supporting the body’s own capacity to detox and heal rather than forcing it. Dr. Nafysa Parpia is the Director of Naturopathic Medicine at Gordon Medical, where she specializes in tick-borne illness, ME/CFS, mold and mycotoxin illness, mast cell activation, environmental toxicity, and the complex chronic conditions rooted in immune dysregulation and persistent infection that often don’t respond to standard protocols. A graduate of Bastyr University and a board member of the International Society for Environmentally Acquired Illness (ISEAI), she is known for a careful, sequenced approach to detoxification, testing thoughtfully and supporting the body’s foundations, nutrients, gut, and detox pathways, before trying to clear anything. Together, she and Dr. Gordon treat each patient as an “N of one.” Websites: https://gordonmedical.com; https://www.gordonmedicalforum.com - - - - - Nancy O’Hara, MD, MPH, FAAP, FMAPS Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.drohara.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/drnancyohara/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/nhoharamd/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/nancy-o-hara-md-mph-faap-390781258/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Join our listeners on ⁠⁠⁠⁠⁠⁠⁠⁠Spotify⁠⁠⁠⁠⁠⁠⁠⁠, ⁠⁠⁠⁠⁠⁠⁠⁠Apple Podcasts⁠⁠⁠⁠⁠⁠⁠⁠, and ⁠⁠⁠⁠⁠⁠⁠⁠iHeart Radio⁠⁠⁠⁠⁠⁠⁠⁠. - - - - - PODCAST Thank you for listening. Please subscribe and share. This podcast is produced by DrTalks.com https://drtalks.com/podcast-service/

  3. Jul 15

    What Most Doctors Miss About Keto for Autism and PANS

    In this episode, I talk with my longtime friend and colleague Dr. Julie Buckley about something she has been refining for years: a dairy-free ketogenic diet for children with autism, PANS/PANDAS, and seizures. Julie explains why dropping dairy matters so much. Because plant-based, medium-chain fats are far more ketogenic than animal fat, she can keep the ratio low enough that her daughter still enjoys nectarines, tomatoes, and cucumbers at nearly every meal. We talk about how those medium-chain fats feed the mitochondria directly, why that matters for the brain, and how a food-first approach may ease the need for supplements or medications that sometimes leave our children more anxious or agitated. We also open up a newer conversation about peptides, and Julie shares the early, carefully tracked observations from her practice. Woven through all of it is a theme I care about deeply: food as nourishment and connection, not restriction. Julie's stories about getting children into the kitchen, and about her own daughter's wisdom and humor, are a reminder that this work is about supporting the whole child and the whole family. It is treatable, it does exist, and it takes a village. - - - - - About the Guest: Dr. Julie Buckley is a pediatrician and functional medicine physician in Ponte Vedra Beach, Florida, where her practice, Pediatric Partners of Ponte Vedra, cares for children of all ages. A graduate of the University of Miami School of Medicine and the Jackson Memorial Hospital pediatric residency, she became one of the first pediatricians in the world to complete the Institute for Functional Medicine's certification in 2016. Her work grew out of her own family. She turned to functional, root-cause medicine after her daughter regressed into autism at age four, and deepened it after her own breast cancer diagnosis in 2009. She is the author of Healing Our Autistic Children, an international speaker on autism and related disorders, and the founder of the HealthyUNow Foundation, a nonprofit building educational, therapeutic, and residential support for individuals and families affected by autism. - - - - - Social Handles: Website: https://pppvonline.comFoundation: https://healthyunow.orgLinkedIn: https://linkedin.com/in/julie-buckley-b24944102 - - - - - Nancy O’Hara, MD, MPH, FAAP, FMAPS Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.drohara.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/drnancyohara/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/nhoharamd/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/nancy-o-hara-md-mph-faap-390781258/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Join our listeners on ⁠⁠⁠⁠⁠⁠Spotify⁠⁠⁠⁠⁠⁠, ⁠⁠⁠⁠⁠⁠Apple Podcasts⁠⁠⁠⁠⁠⁠, and ⁠⁠⁠⁠⁠⁠iHeart Radio⁠⁠⁠⁠⁠⁠. - - - - - PODCASTThank you for listening.Please subscribe and share.This podcast is produced by DrTalks.comhttps://drtalks.com/podcast-service/

  4. Jul 1

    A Smarter Way to Approach Vaccines in Neurodivergent Kids

    What if the most important vaccine question is not yes or no—but which child, which timing, and under what conditions? In this episode of Demystifying PANS/PANDAS, Dr. Nancy O'Hara speaks with Dr. Ari Calhoun about immune activation, genetic susceptibility, microglial signaling, and why some children may be more vulnerable to neuroimmune responses when vaccines are given during sensitive developmental windows or periods of higher inflammatory load. They explore how vaccine reactions may be shaped by immune pathway differences, maternal and early life antecedents, microbiome health, family history, and total immune burden. Dr. Calhoun also explains practical ways to reduce risk through informed consent, schedule adjustments, spacing, brand selection, and targeted nutritional and anti-inflammatory support—offering families a more individualized path that moves beyond fear and toward thoughtful, child-centered care. - - - - - About the Guest: Dr. Ari Calhoun, FMAPS is a naturopathic doctor and the founder of Wholesome Brain Medicine, where she specializes in the treatment and prevention of neurodevelopmental and pediatric neuropsychiatric conditions. Her work spans autism, ADHD, PANS/PANDAS, anxiety, OCD, tics, mood disorders, and other brain-based conditions, with a focus on how the immune system, metabolism, genetics, and the environment shape neurodevelopment and long-term mental health. She is widely known for her thoughtful, science-based work in vaccine risk assessment and individualized immune support, helping families navigate complex vaccination decisions while protecting neurodevelopment and supporting resilience. Her clinical approach begins as early as preconception and extends through pregnancy, childhood, and adolescence. - - - - - Social Handles: Website: https://wholesomebrainmedicine.com/Instagram: https://www.instagram.com/dr.aricalhoun/LinkTree: https://linktr.ee/dr.aricalhoun - - - - - Nancy O’Hara, MD, MPH, FAAP, FMAPS Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.drohara.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/drnancyohara/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/nhoharamd/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/nancy-o-hara-md-mph-faap-390781258/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Join our listeners on ⁠⁠⁠⁠⁠Spotify⁠⁠⁠⁠⁠, ⁠⁠⁠⁠⁠Apple Podcasts⁠⁠⁠⁠⁠, and ⁠⁠⁠⁠⁠iHeart Radio⁠⁠⁠⁠⁠. - - - - - PODCASTThank you for listening.Please subscribe and share.This podcast is produced by DrTalks.comhttps://drtalks.com/podcast-service/

  5. Jun 17

    When Screen Time Starts Looking Like Addiction

    What if the real problem is not just screen time, but what constant digital stimulation is doing to a child's brain, mood, and ability to cope? In this episode of Demystifying PANS/PANDAS, We speak with Dr. Koichi Tanji about the sharp rise in recreational screen use, how to tell the difference between overuse and addiction, and why chronic gaming, social media, and online stimulation can impair attention, increase anxiety, and erode real-world connection. We explore how screen dependence can show up as irritability, boredom intolerance, poor boundaries, social withdrawal, sleep disruption, and loss of motivation, along with why these patterns can be especially complicated in neurodivergent children or kids with deeper physiological stress. Koichi also explains how families can begin reducing screen dependence through awareness, structure, replacement activities, and individualized support rather than shame or oversimplified rules alone. - - - - - About the Guest: Dr. Koichi Tanji ND, LMHC, FMAPS is a clinician and counselor who works closely with children and families navigating screen dependence, behavioral dysregulation, anxiety, and neurodivergence. He is known for helping parents understand how chronic recreational screen use can affect the developing brain, emotional regulation, motivation, and social functioning in the digital era. Drawing from both clinical experience and research, Koichi brings a practical and compassionate lens to the conversation around gaming, social media, and digital overstimulation. His work focuses on helping families build awareness, restore boundaries, and support children in reconnecting with healthier rhythms, relationships, and coping strategies. - - - - - Social Handles: Instagram: https://www.instagram.com/be_better_with_koichi/Email: dr.koichitanji@gmail.com - - - - - Nancy O’Hara, MD, MPH, FAAP, FMAPS Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.drohara.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/drnancyohara/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/nhoharamd/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/nancy-o-hara-md-mph-faap-390781258/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Join our listeners on ⁠⁠⁠⁠Spotify⁠⁠⁠⁠, ⁠⁠⁠⁠Apple Podcasts⁠⁠⁠⁠, and ⁠⁠⁠⁠iHeart Radio⁠⁠⁠⁠. - - - - - PODCASTThank you for listening.Please subscribe and share.This podcast is produced by DrTalks.comhttps://drtalks.com/podcast-service/

  6. Jun 3

    When Neurodevelopmental Symptoms Start in the Womb

    What if a child's neuroinflammation began long before the first symptoms appeared? In this episode of Demystifying PANS/PANDAS, Dr. Somer DelSignore joins us to speak about congenital vector-borne infections and how in utero exposure to pathogens and maternal immune activation may influence brain development, immune programming, and later neuropsychiatric or developmental challenges. They explore why pregnancy timing matters, which early signs may raise suspicion, why negative testing does not always rule out transmission, and how hidden infectious burdens can sit beneath labels like PANS, autism, or autoimmune encephalopathy. Dr. DelSignore also shares the thinking behind her RESET Protocol and why lasting recovery often requires addressing inflammation, infections, gut health, toxins, detoxification, and nervous system support together. - - - - - About the Guest: Dr. Somer DelSignore, DNP, BC-PNP, FMAPS, ILADS, FAAOT is a board-certified child and adolescent provider known for her expertise in diagnosing and managing complex chronic illness in children. She is the CEO and founder of Hudson Valley Integrative Health and has developed the RESET Protocol, a root-cause framework designed to address immune dysfunction systematically. She is a fellow at MAPS and AAOT, a member of ILADS, and has deep experience in autoimmune and neuroimmune conditions, along with the psychiatric manifestations of infectious disease, especially tick-borne infections. Dr. DelSignore earned her Master of Nursing Practice from the University of Pennsylvania and her Doctor of Nursing Practice from SUNY Upstate Medical University, and completed residencies at CHOP, Penn State, and Children's Health in Dallas. - - - - - Hopewell is a family-owned pharmacy which has been in existence since 1987. You can call them at800-792-6670, email them at info@hopewellrx.com or visit them online at www.hopewellrx.com.Hopewell Pharmacy: Your partner in integrative wellness. Other Links for the Guest: Website: https://hudsonvalleyintegrativehealth.com/LinkedIn: https://www.linkedin.com/in/somerdelsignorekidslyme/ - - - - - Nancy O’Hara, MD, MPH, FAAP, FMAPS Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.drohara.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/drnancyohara/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/nhoharamd/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/nancy-o-hara-md-mph-faap-390781258/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Join our listeners on ⁠⁠⁠Spotify⁠⁠⁠, ⁠⁠⁠Apple Podcasts⁠⁠⁠, and ⁠⁠⁠iHeart Radio⁠⁠⁠. - - - - - PODCASTThank you for listening.Please subscribe and share.This podcast is produced by DrTalks.comhttps://drtalks.com/podcast-service/

  7. May 20

    How Parents Can Stop Feeding the Worry Loop

    Sometimes the behaviors families rush to fix are actually part of a larger anxiety loop happening inside the home. In this episode of Demystifying PANS/PANDAS, Dr. Nancy O’Hara speaks with Dr. Sarah Bren about why therapy can be such a powerful and flexible tool for anxious children, and how the SPACE model helps parents shift patterns that may be unintentionally maintaining symptoms. They discuss the difference between reducing anxiety and building tolerance for it, why reassurance and accommodations can keep children dependent on rescue, and how supportive statements help kids feel both safe and capable. Dr. Bren also explains how this work applies not only to anxiety and OCD, but also to emotional dysregulation, sibling dynamics, and family systems where one or both parents feel stuck in opposite roles. - - - - - About the Guest: Dr. Sarah Bren is a clinical psychologist, mom of two, and the co-founder and clinical director of Upshur Bren Psychology Group in Pelham, New York. She has dedicated her career to translating the science of attachment into simple, real-life strategies that support children's development while also protecting parental mental health. She is also the host of the parenting podcast Securely Attached, a top-ranked show focused on pregnancy, toddlerhood, adolescence, and everything in between. Through her clinical work, parenting resources, and integrative therapeutic approach, Dr. Bren helps families navigate anxiety, attachment, and emotional challenges with clarity, compassion, and practical tools. - - - - - 🎧 Securely Attached Podcast Helping parents navigate the emotional side of raising children, this show blends psychology, attachment theory, and practical strategies to foster resilience and connection. Each episode offers grounded insights that empower families to build stronger bonds and nurture healthy development. Listen on Spotify Listen on Apple Podcasts Websites: https://upshurbren.com/, https://drsarahbren.com/ - - - - - Nancy O’Hara, MD, MPH, FAAP, FMAPS Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.drohara.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/drnancyohara/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/nhoharamd/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/nancy-o-hara-md-mph-faap-390781258/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Join our listeners on ⁠⁠Spotify⁠⁠, ⁠⁠Apple Podcasts⁠⁠, and ⁠⁠iHeart Radio⁠⁠. - - - - - PODCASTThank you for listening.Please subscribe and share.This podcast is produced by DrTalks.comhttps://drtalks.com/podcast-service/

  8. May 6

    Bartonella and PANS: What Clinicians and Families Need to Know

    What if Bartonella is part of the reason some children with PANS remain stuck in cycles of rage, confusion, sleep disruption, and chronic neuropsychiatric symptoms? In this episode of Demystifying PANS/PANDAS, we speak with Dr. Ed Breitschwerdt about why Bartonella deserves much more attention in the PANS world—and why the term 'vector-borne disease' is often more accurate than simply saying Lyme. We discuss the broad range of vectors that may transmit Bartonella, why symptom overlap makes diagnosis difficult, the significance of striae-like skin lesions, and why standard tests often miss infection. Dr. Breitschwerdt also explains how Bartonella can persist in tissues, why triple-draw and molecular testing may improve detection, and why chronic infection, inflammation, and immune dysfunction need a much bigger research response. - - - - - About the Guest: Dr. Ed Breitschwerdt, DVM, DACVIM, PhD is a professor of medicine at North Carolina State University College of Veterinary Medicine, a professor at Duke University, and co-founder of Galaxy Diagnostics. He is a leading expert in Bartonella and vector-borne infectious diseases, with decades of research spanning both animal and human health. A veterinary internist and infectious disease researcher, Dr. Breitschwerdt has authored hundreds of peer-reviewed publications and helped redefine Bartonella as a cause of persistent infection, neurologic disease, and neuropsychiatric illness. His work emphasizes the need for more sensitive diagnostics and expanded research into chronic infection and immune dysfunction. - - - - - Social Handles: Website: https://www.galaxydx.com/; https://cvm.ncsu.edu/people/ebbreits/ Facebook: https://www.facebook.com/galaxydx Instagram: https://www.instagram.com/galaxydiagnostics/ LinkedIn: https://www.linkedin.com/company/galaxy-diagnostics-inc-/ YouTube: https://www.youtube.com/@GalaxyDiagnosticsVideos Explore A Blind Spot on Autism — a powerful resource that challenges misconceptions and brings clarity to the autism journey. Learn more today at ablindspotonautism.com. - - - - - Nancy O’Hara, MD, MPH, FAAP, FMAPS Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.drohara.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/drnancyohara/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/nhoharamd/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/nancy-o-hara-md-mph-faap-390781258/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Join our listeners on ⁠Spotify⁠, ⁠Apple Podcasts⁠, and ⁠iHeart Radio⁠. - - - - - PODCASTThank you for listening.Please subscribe and share.This podcast is produced by DrTalks.comhttps://drtalks.com/podcast-service/

4.9
out of 5
48 Ratings

About

Welcome to the Demystifying PANS/PANDAS Podcast with Dr. Nancy O'Hara! Ever wondered why some kids experience sudden, life-altering behavioral changes? This podcast delves into PANS (Pediatric Acute-onset Neuropsychiatric Syndrome) and PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Strep). Experts explore the triggers, symptoms, and innovative treatments for these autoimmune disorders, blending science and heartfelt guidance. From strep to Lyme, natural therapies, emotional support, and recovery stories—this is your guide to hope and healing.

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