Beauty by the Beaker

Beauty by the Beaker

Welcome to Beauty by the Beaker, a podcast where Science Gets a HOT New Makeover. We're two cosmetic chemists who want to reveal what really goes into your favorite products - and we aren't afraid to bust some myths while doing it. Whether you’re a skincare enthusiast, a curious consumer, or just tired of being told coconut oil cures everything, you’re in the right place. Let's gossip about all things beauty together! Pull up a chair babe, your appointment's about to start.

  1. 5d ago

    Eyelash Serum or Glaucoma Treatment? The Risk and Reward of Prostaglandin Analogs! - EP 45

    What ingredients are in your lash serum? And is it really worth the risk?  Long, luscious lashes are a beauty goal for many, but do you really know what's happening when you use those popular eyelash serums? This week we are diving into an unlikely lash lengthener that was discovered while treating glaucoma. We are telling you everything you need to know about prostaglandin analogs. These ingredients not only stimulate lash growth but can also cause side effects like eye color darkening and sunken under-eye fat. In this eye-opening episode, cosmetic chemists Natalie and Sadie explain the science behind lash enhancers, revealing why they're effective and how they might do more harm than good. We cover:  How prostaglandin analogs influence your hair growth cycle to produce longer, thicker lashes The truth about the only FDA-approved lash serum, Bimatoprost (Latisse), and its risks Why ingredients like peptides and oils might be safer, yet less dramatic, alternatives The potential danger of prostaglandin analogs causing your eye fat to shrink and your iris to darken Practical tips to protect your eyelashes and avoid undesired side effects, focusing on more sustainable routine habits. This episode is great for beauty enthusiasts who want that fluttery lash look without risking their eye health.  Welcome to Beauty by the Beaker, the podcast where Sciences Gets a Hot New Makeover! We're two cosmetic chemists who want to reveal what really goes into your favorite products. Join us in the Science Salon! Whether you’re a skincare enthusiast, a curious consumer, or just tired of being told coconut oil cures everything, you’re in the right place. Let's gossip about all things beauty together! Pull up a chair, your appointment's about to start. Timestamps: 00:00 - The chemistry behind lash serums and their effects 00:40 - The biology of eyelash phases and how serums extend growth 02:14 - Side effects: fat loss under the eyes and eye discoloration 03:02 - Glaucoma, prostaglandin analogs, and their accidental lash-growing effects 04:17 - The mechanism of prostaglandin analogs on eyelashes and eye health 05:09 - FDA-approved lash ingredients versus marketing claims 06:02 - The eyelash growth cycle and how serums hijack the process 07:27 - How prostaglandin analogs can cause eyelid and eye color changes 08:27 - Reversibility of fat loss and risks of eye pigmentation 09:25 - Safe lash practices and alternative products 10:11 - Summary of risks and safety tips for users of lash serums 11:04 - Making your lashes appear longer with makeup tricks 12:12 - Practical advice for protecting natural lashes and monitoring side effects 13:40 - The importance of clinical evidence in choosing lash serums 14:25 - Everyday habits influencing lash health and longevity 15:46 - Final safety considerations and product recommendations 16:36 - Enhancing lash appearance with makeup techniques 17:00 - Final thoughts Visit our website to read more about this episode and check out our blog post with more sources. www.beautyxbeaker.com Join us on Instagram, Facebook, TikTok and Youtube! @beautyxbeaker @natbxb @sadiebxb Contact us at info@beautyxbeaker.com Special thanks to Flip Twogood for our photos and music and Hailey Romero for our branding.

  2. Jul 29

    Exosomes Work! What About In Skincare? The Truth Behind 'Regenerative' Cosmetics - EP44

    Exosomes are rapidly becoming the hottest buzzword in skincare, but what do we really know about their power? Are they the regenerative breakthrough they're made out to be, or simply a clever marketing tactic? If you're curious about whether products claiming to harness these tiny cellular messengers are worth your hard-earned money, this episode is for you! As cosmetic chemists, we cut through the hype to explain what exosomes are, and more importantly, what they aren’t. We are breaking down the science behind these cell signaling vesicles, why their source (human, plant, bacteria, or fungus) matters immensely, and what current research really says about their ability to improve skin. We dive into the biggest misconceptions, including the limitations of topical delivery, the regulation hurdles, and why the price tags often don’t match the proven benefits. We explain the different sources of exosomes, and explore the promising data behind human-derived strains from blood and stem cells, but of course we also highlight just how early-stage and inconclusive most studies remain. We cover some questionable delivery methods like microneedling, patches, and other in-office procedures that might enhance absorption, and why many topical products may never penetrate a healthy skin barrier effectively. Without proper regulation and solid science, many products may be more about impression than efficacy. And we obviously need to cover the regulations, so we highlight how unsubstantiated claims cross into unapproved drug territory, putting consumers at risk. Understanding these nuances helps you make smarter choices, avoid wasted money, and set realistic expectations for skin ‘rejuvenation.’ Welcome to Beauty by the Beaker, the podcast where Sciences Gets a Hot New Makeover! We're two cosmetic chemists who want to reveal what really goes into your favorite products. Join us in the Science Salon! Whether you’re a skincare enthusiast, a curious consumer, or just tired of being told coconut oil cures everything, you’re in the right place. Let's gossip about all things beauty together! Pull up a chair, your appointment's about to start. Timestamps: 00:00 - What are exosomes and why they're key in skincare marketing 02:00 - How exosomes function as cell-to-cell messengers 03:30 - Different sources of exosomes: human, plant, bacteria, and fungi 05:00 - The significance of exosome source on their messaging and effectiveness 07:00 - Challenges of topical delivery and clinical methods to bypass the skin barrier 10:00 - Regulatory status: FDA approval and legal concerns around exosome claims 14:00 - Evidence supporting the use of human-derived exosomes in skincare 16:00 - The potential and limitations of bacteria and plant-derived exosomes 22:00 - Cost implications: why certain products are more expensive and what that indicates 26:00 - Formulation hurdles: stability, storage, and ensuring activity over shelf life 30:00 - Efficacy expectations: what current science can and can't promise 36:00 - Practical advice: whether to invest in exosome products or opt for proven treatments 38:00 - The primary target of skin aging treatments - sun protection and retinoids 39:00 - Final thoughts: the future of exosome research and regulatory developments Visit our website to read more about this episode and check out our blog post with more sources. www.beautyxbeaker.com Join us on Instagram, Facebook, TikTok and Youtube! @beautyxbeaker @natbxb @sadiebxb Contact us at info@beautyxbeaker.com Special thanks to Flip Twogood for our photos and music and Hailey Romero for our branding.

  3. Jul 22

    K-Beauty Takeover! The History, Hype, and the Mythical 10-Step Skincare Routine - EP 43

    Welcome back to the Science Salon! You might claim to be a K-beauty fan, but did you know that it’s a result of Korea’s strategic comeback after the 1997 Asian financial crisis? And was Missha the first Ordinary when it comes to simple and effective, no-frills skincare? This week is part 2 of our K Beauty series, and this week we are discussing all things Hallyu, or the Korean Wave. We break down how Korean beauty became a worldwide phenomenon, why the 10-step Korean skincare routine took off, and what people often get wrong about K-beauty trends (especially regarding sun protection).  Welcome to Beauty by the Beaker, the podcast where Sciences Gets a Hot New Makeover! We're two cosmetic chemists who want to reveal what really goes into your favorite products. Join us in the Science Salon! Whether you’re a skincare enthusiast, a curious consumer, or just tired of being told coconut oil cures everything, you’re in the right place. Let's gossip about all things beauty together! Pull up a chair, your appointment's about to start. In this episode we cover: What is K-beauty? Is the 10-step Korean skincare routine really necessary? Why is Korean skincare so focused on prevention? How did K-beauty spread globally? What are the cultural and economic forces behind Korean beauty? This episode explores the history of Hallyu, the Korean wave, and how Korean media, K-pop, K-dramas, and beauty products helped shape global beauty standards. We also talk about the benefits and drawbacks of beauty culture, the pressure to look perfect, and why sunscreen, hydration, and prevention are so central to Korean skincare. We mention brands and concepts like Amorepacific, Innisfree, BB cream, cushion foundations, sheet masks, road shops, and the intentional marketing behind K-beauty’s global success. We also discuss how social media and TikTok have influenced the way people think about skincare routines, beauty standards, and “perfect skin.” Whether you’re here for Korean skincare, K-beauty history, beauty science, or cultural analysis, this episode has you covered. Chapters: 00:00 Intro 02:16 Continuing the K-beauty conversation 05:43 Korea’s export strategy and soft power 10:02 The rise of K-beauty brands 28:18 BB cream and cushion makeup 32:27 The 10-step Korean skincare routine 38:07 Sunscreen, prevention, and beauty culture 41:46 The pressure of never being enough Key Sources  https://elisehu.com/flawless/ Glass Skin, Colourism & SPF Scandals: The Truth Behind The Rise Of Korean Beauty - Behind The Beauty Why are South Korean cosmetics so popular? | The Global Story Podcast Visit our website to read more about this episode and check out our blog post with more sources. www.beautyxbeaker.com Join us on Instagram, Facebook, TikTok and Youtube! @beautyxbeaker @natbxb @sadiebxb Contact us at info@beautyxbeaker.com Special thanks to Flip Twogood for our photos and music and Hailey Romero for our branding.

  4. Jul 15

    K-Beauty is Ancient History | Korean Skincare Before Hallyu - EP42

    You can’t be a skincare fan and not know about K-Beauty. Today we are talking about the history behind Korea’s astonishing rise to global beauty powerhouse. It’s more than just cosmetic, it’s a story of resilience, strategy, and innovation. Most Americans overlook Korea’s deep history, but a centuries-old story of oppression, evolution, and social shifts laid the groundwork for today’s K-beauty craze. We are going all the way back to the beginning, and looking at how ancient legends and the strict standards of Confucianism laid the groundwork for modern beauty culture.  Welcome to Beauty by the Beaker, the podcast where Sciences Gets a Hot New Makeover! We're two cosmetic chemists who want to reveal what really goes into your favorite products. Join us in the Science Salon! Whether you’re a skincare enthusiast, a curious consumer, or just tired of being told coconut oil cures everything, you’re in the right place. Let's gossip about all things beauty together! Pull up a chair, your appointment's about to start. This episode is for anyone wondering how history can shape beauty standards.  We cover: How ancient Korean beauty standards prioritized external health and inner vitality. Skincare using ingredients like rice water, green tea, and ginseng. The fascinating roles women like the Gisang played as both entertainers and pioneers of skincare techniques, including early double cleansing. The impact of Korea’s political upheavals, from Japanese occupation and the Korean War to the rise of Hallyu, in shaping the industry’s resilience and innovation. The emergence of iconic products like Bakgabun powder, and its lead poisoning downfall, highlighting early challenges in establishing successful skincare lines. How Korea’s cultural exports like K-pop, dramas, and movies have created a global fascination that fueled the Korean Wave (Hallyu), turning to soft power with enormous economic influence. 00:00 — The Origins of K-Beauty and Korean History 06:53 — Cultural Influences and Historical Context 09:42 — Beauty Standards Through the Ages 13:33 — The Impact of Confucianism on Beauty 21:32 — Japanese Occupation and Its Effect on Korean Exports 25:50 — The Rise of Korean Cosmetics 30:26 — The Emergence of the Modern Girl 32:42 — The Birth of Amore Pacific 35:57 — Challenges During the Korean War 38:37 — The Impact of Political Regimes on Beauty Standards 40:49 — The Factory Girl Aesthetic 43:34 — The Shift Towards Democracy and Globalization 46:22 — The Korean Wave and Its Influence on Beauty 49:46 — Conclusion: Like, Subscribe and Follow Key Sources  https://elisehu.com/flawless/ Visit our website to read more about this episode and check out our blog post with more sources. Join us on Instagram, Facebook, TikTok and Youtube! @beautyxbeaker @natbxb @sadiebxb Contact us at info@beautyxbeaker.com Special thanks to Flip Twogood for our photos and Hailey Romero for our branding.

  5. Jul 1

    Can Skincare Products Cure Weight Loss Side Effects? - EP41

    I bet you have heard of Ozempic, but did you know it was first discovered in Gila Monster venom? This week we are talking about weight loss drugs, and the shocking side effects they can cause. If you're curious about the science, the beauty industry's profit-driven response, and why these weight-loss drugs might be doing more harm than good, this episode is your essential guide. We talk about the mechanism of action, and how it's used for managing blood sugar and suppressing appetite. We’re talking all about how and why these drugs work, and why their popularity has skyrocketed beyond medical need into the realm of aesthetic obsession. We break down the real risks, like facial volume loss, "Ozempic face," and the accelerated aging many users are experiencing. We reveal how the beauty and skincare industry is quick to cash in on these side effects, marketing products that promise to reverse or hide the very issues caused by these powerful medications. You'll learn why topical treatments and expensive serums are often a marketing illusion that can't substitute real medical procedures for lifting or tightening skin. This episode is for anyone concerned with body image, or interested in understanding the truth behind rapid weight loss and beauty industry hype. As cosmetic chemists, our goal is to help you recognize the industry’s tactics designed to profit from insecurities. Because understanding the science and the industry’s game means you're less likely to fall prey to false promises. Note: We are not medical professionals. Always consult with a healthcare provider before making decisions about your health or medication. This episode offers context and insights but is not medical advice. Welcome to Beauty by the Beaker, the podcast where Sciences Gets a Hot New Makeover! We're two cosmetic chemists who want to reveal what really goes into your favorite products. Join us in the Science Salon! Whether you’re a skincare enthusiast, a curious consumer, or just tired of being told coconut oil cures everything, you’re in the right place. Let's gossip about all things beauty together! Pull up a chair, your appointment's about to start. Visit our website to read more about this episode and check out our blog post with sources. Join us on Instagram, Facebook, TikTok and Youtube! @beautyxbeaker @natbxb @sadiebxb Contact us at info@beautyxbeaker.com Special thanks to Flip Twogood for our photos and Hailey Romero for our branding. In this episode: The history of society’s obsession with thinness and the rise of appetite-suppressing drugs How GLP-1 drugs like Ozempic work biologically and their primary purposes The aesthetic side effects associated with rapid weight loss, notably "Ozempic face" The surge of beauty products marketed specifically to mitigate side effects of Ozempic Critical insights into marketing claims around "Ozempic skincare" and fake efficacy The risks of self-prescribing and unregulated beauty solutions Recommendations for safe, effective approaches and consulting professionals Timestamps: 00:00 - Society's obsession with thinness since the 1800s 02:02 - The rise of appetite-suppressing drugs and their side effects 04:13 - Introduction to GLP-1 drugs and their purpose 07:05 - How GLP-1 from venom inspired Ozempic's development 09:23 - Medical uses for GLP-1 drugs in diabetes and weight management 12:13 - Societal pressures fueling misuse of these drugs for aesthetic goals 14:33 - Side effects including "Ozempic face" and facial volume loss 16:05 - The body's natural aging reveal through rapid weight loss 18:18 - Rising cosmetic solutions targeting side effects like sagging skin and dullness 20:09 - Marketed skincare products for "GLP-1 skin concerns" and their questionable claims 22:31 - Evaluation of studies supporting these skincare claims 24:10 - The beauty industry's cycle: creating problems and selling solutions 27:36 - The importance of consulting healthcare professionals before using drugs or products

  6. Jun 24

    Why Does Isotretinoin Work SO WELL? History and Controversy Behind Accutane - EP 40

    This week we are diving deep into Accutane, also known as isotretinoin. This is one of the most talked about acne treatments in dermatology. If you’ve ever wondered how Accutane works, why skin can get worse before it gets better, what the purge phase feels like, or whether Accutane is actually safe, this episode breaks it all down in a science-backed, easy-to-understand way. We cover the accidental discovery of Accutane, the history behind isotretinoin, how it targets sebaceous glands and oil production, and why it’s often considered a last-resort treatment for severe or stubborn acne. We also talk about common Accutane side effects like dry skin, dry lips, bloody noses, joint pain, vision changes, and increased breakouts during the purge phase. You’ll also learn about the iPledge system, the required pregnancy prevention program, the controversy around its new rollout, and the reasons dermatologists and patients have criticized it.  We are discussing the real-world experience of going on Accutane, as well as the emotional side of dealing with Acne. We talk about how to decide with a medical professional, how to determine the right time, if ever, to try this stuff out.  Whether you’re researching Accutane for yourself, comparing acne treatments, or just want to understand the science behind one of dermatology’s most effective medications, this episode is for you. Chapters:  00:00 Intro + why Accutane deserves its own episode 02:03 What Accutane is and what it treats 04:17 How acne actually forms 06:10 The history of Accutane 09:10 Early studies and why it worked so well 13:13 How Accutane works 18:03 Getting prescribed Accutane 19:19 Dosage, cumulative dose, and cost 21:19 Pregnancy testing, birth control, and iPledge 25:15 The iPledge controversy and website overhaul 27:47 Common side effects and purge phase 30:47 Long-term effects and benefits 31:22 Microdosing Accutane 32:14 Does acne come back after Accutane? 33:05 Should you be scared of Accutane? 34:37 Acne stigma and confidence 37:39 Final thoughts on trying Accutane 39:06 Outro Welcome to Beauty by the Beaker, the podcast where Sciences Gets a Hot New Makeover! We're two cosmetic chemists who want to reveal what really goes into your favorite products. Join us in the Science Salon! Whether you’re a skincare enthusiast, a curious consumer, or just tired of being told coconut oil cures everything, you’re in the right place. Let's gossip about all things beauty together! Pull up a chair, your appointment's about to start. Visit our website to read more about this episode and check out our blog post with sources. Join us on Instagram, Facebook, TikTok and Youtube! @beautyxbeaker @natbxb @sadiebxb Contact us at info@beautyxbeaker.com Special thanks to Flip Twogood for our photos and Hailey Romero for our branding.

  7. Jun 18

    EVERYTHING You Need To Know Before Using Bemotrizinol | The HOTTEST New Sunscreen Active! - EP 39

    EMERGENCY SUNSCREEN UPDATE!  The FDA just approved the first UV filter in over 20 years! Join us for breaking news in US sunscreens. This ingredient promises to be the safest and most effective filter the United States Market has ever seen, but what does that actually mean as a consumer?  This week we are telling you EVERYTHING you need to know about Bemotrizinol, BEMT, bis-ethylhexyloxyphenol methoxyphenyl triazine (Which is actually still an INCI name, not IUPAC) Tinosorb S, or Parsol SHIELD. Whatever you decide to call it, we are here to break down what it means for the future of your sun protection products.  Plus we are diving into the history of sunscreen regulation, and explaining why this ingredient is brand new in the US, but has been used abroad for almost 20 years. If you’ve ever wondered why American sunscreens feel different from those in Europe or Korea, this episode unpacks the complex history behind US regulations and the science behind a game-changing sunscreen active, BEMT. We are unpacking how this new ingredient offers broader UV protection, reduces skin irritation, and could finally end the white cast nightmare. Whether you’re a skincare fanatic or just tired of greasy feeling skin, you’ll discover how this novel ingredient could make your sunscreen better, lighter, and more effective, and why it’s a symbol of progress in a long-standing regulatory limbo.  Welcome to Beauty by the Beaker, the podcast where Sciences Gets a Hot New Makeover! We're two cosmetic chemists who want to reveal what really goes into your favorite products. Join us in the Science Salon! Whether you’re a skincare enthusiast, a curious consumer, or just tired of being told coconut oil cures everything, you’re in the right place. Let's gossip about all things beauty together! Pull up a chair, your appointment's about to start. Visit our website to read more about this episode and check out our blog post with sources. Join us on Instagram, Facebook, TikTok and Youtube! @beautyxbeaker @natbxb @sadiebxb Contact us at info@beautyxbeaker.com Special thanks to Flip Twogood for our photos and Hailey Romero for our branding. 0:00 Introduction and Episode Overview 2:10 Emergency Sunscreen Update   3:05 Understanding Sunscreen Ingredients  16:33 FDA Approval Process Explained  19:08 Historical Context of Sunscreen Regulation 25:43 Future of Sunscreen in the US 32:58 Conclusion and Social Media Call to Action Sources:  https://www.fda.gov/news-events/press-announcements/fda-expands-sunscreen-options-first-time-20-years https://www.npr.org/2026/06/13/nx-s1-5856385/sunscreen-skin-protection-bemotrizinol https://labmuffin.com/how-do-sunscreens-work-the-science-with-video/ https://pmc.ncbi.nlm.nih.gov/articles/PMC8682817/ https://www.fda.gov/drugs/historical-status-otc-rulemakings/rulemaking-history-otc-sunscreen-drug-products https://www.govinfo.gov/content/pkg/FR-1999-05-21/pdf/99-12853.pdf https://pmc.ncbi.nlm.nih.gov/articles/PMC12332967/ https://thehill.com/policy/healthcare/5922475-bemotrizinol-sunscreen-approval-fda/

  8. Jun 11

    Is Looksmaxxing The Answer To A Bigger Problem? - EP 38

    0:00 - Introduction to Looksmaxxing  Discussion on the concept and its societal implications. 15:18 - A Never Ending Pursuit For Perfection How looksmaxxing has roots in historical beauty practices. 19:06 - Modern Trends and Influences  The role of social media and influencers in popularizing looksmaxxing. 21:35 - Gender Perspectives  Differences in beauty standards and expectations for men and women. 25:14 - Psychological and Social Impacts How looksmaxxing affects self-esteem and social interactions. 28:31 - Ethical Considerations  The dangers and ethical concerns surrounding extreme beauty practices. 29:37 - Conclusion and Personal Reflections  Final thoughts on the future of beauty standards and personal empowerment. This week we are diving into a HOT topic - Looksmaxxing. Most of society can agree that appearance ISN’T everything, but why haven’t we ever been able to move past the importance of our looks? and why are straight men suddenly going to such dangerous lengths to maxximize their appearance? In this provocative episode, we unravel the (not so) surprising parallels between gendered beauty practices and the extreme phenomenon of looksmaxxing among men, from steroid injections to bone smashing. Is this just a new twist on a tale as old as time? Join us in the Science Salon, and discover how the desire for societal acceptance fuels this dangerous trend and why mainstream media, social media, and even medical professionals play a role in pushing these extreme practices. We break down the origins of looks maxxing, revealing how a 2010s niche internet phenomenon has become a mainstream obsession. We explore the impact of black pill ideology, where appearance is seen as the only way to social mobility, and why society's system of beauty standards needs urgent reevaluation. We analyze real examples like Braden Peters, better known as  "Clavicular", the TikTok star injecting steroids and smashing his jaw, and examine how younger generations are risking their health in pursuit of perfection. We are talking about the dangerous extremes like plastic surgery, illegal drugs, and body modifications that are widely normalized in the beauty industry, even if they are inherently reckless.  Beyond the shock factor, this episode challenges you to think about the systemic pressures behind looksmaxxing. Is this merely individual vanity, or are we all complicit in a system that prizes superficial beauty over genuine confidence? We consider how media, societal expectations, and gender stereotypes shape this obsession, and what we can do to foster self-love and confidence outside of appearance. At the end of the day, the non stop pursuit of perfection is in vain. Remember to love each other, and look for ways to help people out. BXB welcomes all, no matter their physical appearance.   Welcome to Beauty by the Beaker, the podcast where Sciences Gets a Hot New Makeover! We're two cosmetic chemists who want to reveal what really goes into your favorite products. Join us in the Science Salon! Whether you’re a skincare enthusiast, a curious consumer, or just tired of being told coconut oil cures everything, you’re in the right place. Let's gossip about all things beauty together! Pull up a chair, your appointment's about to start. Visit our website to read more about this episode and check out our blog post with sources. Join us on Instagram, Facebook, TikTok and Youtube! @beautyxbeaker @natbxb @sadiebxb Contact us at info@beautyxbeaker.com Special thanks to Flip Twogood for our photos and Hailey Romero for our branding. Key Sources:  https://www.youtube.com/watch?v=pvqBPkJIkmc&list=PLV7JqwvL7SSsYciULwVUZuYwXPZybUDHN https://www.youtube.com/watch?v=CXKCoFz3WRs&list=PLV7JqwvL7SSsYciULwVUZuYwXPZybUDHN

4.9
out of 5
25 Ratings

About

Welcome to Beauty by the Beaker, a podcast where Science Gets a HOT New Makeover. We're two cosmetic chemists who want to reveal what really goes into your favorite products - and we aren't afraid to bust some myths while doing it. Whether you’re a skincare enthusiast, a curious consumer, or just tired of being told coconut oil cures everything, you’re in the right place. Let's gossip about all things beauty together! Pull up a chair babe, your appointment's about to start.

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