Dr. M's Women and Children First Podcast

Dr. Chris Magryta, "Dr. M"
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Providing listeners with cutting edge science based information for maternal and child health

  1. 6D AGO

    Dr. M’s SPA Newsletter Volume 15 Issue 32 – Year in Review: 2025

    The Year in Review - 2025 Articles and Points of Interest: 1) Microplastics in the Brain - From Science Advances: "Human health is being threatened by environmental microplastic (MP) pollution. MPs were detected in the bloodstream and multiple tissues of humans, disrupting the regular physiological processes of organs. Nanoscale plastics can breach the blood-brain barrier, leading to neurotoxic effects. How MPs cause brain functional irregularities remains unclear. This work uses high-depth imaging techniques to investigate the MPs within the brain in vivo. We show that circulating MPs are phagocytosed and lead these cells to obstruction in the capillaries of the brain cortex. These blockages as thrombus formation cause reduced blood flow and neurological abnormalities in mice. Our data reveal a mechanism by which MPs disrupt tissue function indirectly through regulation of cell obstruction and interference with local blood circulation, rather than direct tissue penetration. This revelation offers a lens through which to comprehend the toxicological implications of MPs that invade the bloodstream." (Huang et. al. 2025) 2) From Nature Medicine: "Brain insulin responsiveness is linked to long-term weight gain and unhealthy body fat distribution. Here we show that short-term overeating with calorie-rich sweet and fatty foods triggers liver fat accumulation and disrupted brain insulin action that outlasted the time-frame of its consumption in healthy weight men. Hence, brain response to insulin can adapt to short-term changes in diet before weight gain and may facilitate the development of obesity and associated diseases." (Pullman et. al. 2025).... Dr. M

    24 min

  2. JAN 3

    Dr. M’s Women and Children First Podcast #104: SMaeve O’Connor, MD – Allergy and Immune Literacy

    Today, I’m joined by Dr. Maeve O’Connor, a board-certified allergist and immunologist practicing in Charlotte, North Carolina. Dr. O’Connor’s training reflects both rigor and range. She completed dual undergraduate degrees at the University of South Carolina Honors College with a Bachelor of Science in Biology and a Bachelor of Arts in Spanish before earning her medical degree at the University of South Carolina School of Medicine. She then completed her internship and residency at the University of Texas and its affiliated hospitals in Houston, where she served as Chief Medical Resident. Her subspecialty training in Allergy and Immunology was completed at the National Jewish Medical and Research Center in Denver consistently ranked the number one respiratory hospital in the United States where she developed deep expertise in asthma, allergic disease, and immune dysregulation. She further expanded her clinical lens through fellowship training in Integrative Medicine at the University of Arizona from 2013 to 2015. Clinically, Dr. O’Connor works at the intersection of pediatrics, immunology, and real family life where eczema isn’t just a rash, food reactions aren’t just labels, and immune symptoms rarely fit neatly into algorithmic boxes. Her work emphasizes careful diagnosis, evidence-based treatment, and avoiding both over-medicalization and missed pathology. In a time when allergy medicine is often reduced to test results and avoidance lists, Dr. O’Connor brings a grounded, thoughtful approach helping families and clinicians distinguish what’s truly allergic, what’s inflammatory, what’s developmental, and what’s simply noise. Today, we’ll explore how allergic disease actually presents in children, why mislabeling is so common, how early immune signals shape long-term health, and how pediatricians and specialists can collaborate more effectively without fear-based medicine. This is a conversation about immune literacy, clinical nuance, and doing better for children in a world where their immune systems are under increasing pressure. I’m excited to welcome Dr. Maeve O’Connor. Dr. M

  3. 12/31/2025

    Dr. M’s SPA Newsletter Volume 15 Issue 31 – Poly Vagal Theory, Stephen Porges, PhD

    I think that this is an important time to pause and relook at Polyvagal Theory before continuing with Beyond Behaviors. Polyvagal Theory: Current Status, Clinical Applications, and Future Directions (Porges, S. 2025) "Social behavior and the capacity to manage challenge are dependent on the neural regulation of physiological state." S. Porges   When I dove into Stephen Porges’s 2025 review of the Polyvagal Theory (PVT), I felt like I’d stepped into a crossroads where neurobiology, clinical practice, trauma science, and human experience collide. This paper isn’t merely a summary of three decades of work (all of which I have read); it’s a spirited defense of a paradigm that’s been both celebrated (by me) and contested (by others). What follows is an honest appraisal of what the article teaches us, where it sparks real insight, and where it may fall short, especially through the lens of evidence-based medicine and developmental neurophysiology. (I also went deeper into his 2022 paper in Frontiers in Integrative Neuroscience for the biophysiology of the ANS) At its heart, the article argues that the autonomic nervous system (ANS), through a set of hierarchically organized circuits centered on the vagus nerve, is not just a background player in stress and homeostasis, but a core regulator of social engagement, physiological flexibility, and behavior. Dr. Porges situates his theory as an alternative and expansion to classical views that treat sympathetic (fight/flight) and parasympathetic (rest/digest) branches as functional opposites. Instead, he proposes a three-component hierarchy: the ventral vagal complex (VVC) supporting social engagement, a mobilization circuit mediated by the sympathetic nervous system or fight or flight state, and a dorsal vagal circuit that facilitates shutdown or immobilization under extreme threat..... Enjoy, Dr. M

  4. 12/30/2025

    Dr. M’s Women and Children First Podcast #69 Repost – Stephen Porges, Ph.D. – Polyvagal Theory

    This week I sit down with Dr. Stephen Porges, a Distinguished University Scientist at Indiana University where he is the founding director of the Traumatic Stress Research Consortium. He is Professor of Psychiatry at the University of North Carolina, and Professor Emeritus at both the University of Illinois at Chicago and the University of Maryland. He served as president of the Society for Psychophysiological Research and the Federation of Associations in Behavioral & Brain Sciences and is a former recipient of a National Institute of Mental Health Research Scientist Development Award. He has published more than 400 peer-reviewed papers across several disciplines including anesthesiology, biomedical engineering, critical care medicine, ergonomics, exercise physiology, gerontology, neurology, neuroscience, obstetrics, pediatrics, psychiatry, psychology, psychometrics, space medicine, and substance abuse. In 1994 he proposed the Polyvagal Theory, a theory that links the evolution of the mammalian autonomic nervous system to social behavior and emphasizes the importance of physiological state in the expression of behavioral problems and psychiatric disorders. The theory is leading to innovative treatments based on insights into the mechanisms mediating symptoms observed in several behavioral, psychiatric, and physical disorders. ​ He is the author of multiple books on his Polyvagal Theory: including the Neurophysiological foundations of Emotions, Attachment, Communication, and Self-regulation, as well as Polyvagal Safety: Attachment, Communication, Self-Regulation. His newest book cowritten with his son is called Our Polyvagal World, How Safety and Trauma Change Us. Dr. Porges is the creator of a music-based intervention, the Safe and Sound Protocol ™ (SSP), which is used by therapists to improve social engagement, language processing, and state regulation, as well as to reduce hearing sensitivities. This is such a fascinating conversation. He brings the worlds of psychiatry and anthropological physiology into union for us to understand the why of trauma reactions and the future unwinding that is now possible. This is a must listen to conversation if you know anyone with trauma history. Please enjoy my conversation with Professor Porges, Dr. M

  5. 12/26/2025

    Dr. M’s SPA Newsletter Volume 15 Issue 30 – Beyond Behaviors Part 2, Mona Delahooke, PhD

    Review of Chapter 2 of Beyond Behaviors by Mona Delahooke, PhD  "Social behavior and the capacity to manage challenge are dependent on the neural regulation of physiological state." S. Porges  Top Down or Bottom Up? "Before We Respond to Behavior, We Need to Understand Its Origin." With a deceptively simple observation, Dr. Delahooke reshapes the entire field of behavioral intervention: children’s actions come from two very different places in the brain. Some behaviors are top-down, intentional, planned, thoughtful. But many, especially the ones adults find most perplexing, arise bottom-up from stress responses generated by the body’s autonomic nervous system. We often think of this state in terms of fight or flight, however, it is not that simplistic. It is truly any significant response to the outside environment that leads to a neuroceptive reaction that is not governed by the neocortex, top down. If we don’t distinguish the source, our interventions are guesswork at best and often counterproductive at worst. She illustrates this through a case, a child whose impulsive, disruptive behaviors were treated as failures of will or desire. School teachers and teams repeatedly urged him to “use his words,” as though language were a faucet he simply refused to turn on. What no one stopped to ask was the foundational question: Was his nervous system regulated enough to access language at all? Was he gated at the level of the amygdala blocking the ability to use his mind consciously and even have the opportunity to respond to a meaningful request? Is he capable of the ask, not in terms of willingness, but in terms of physiological access to the skill itself? ..... and more Enjoy, Dr. M

  6. 12/13/2025

    Dr. M’s SPA Newsletter Volume 15 Issue 29 – Beyond Behaviors, Mona Delahooke, PhD

    Review of Chapter 1 of Beyond Behaviors by Mona Delahooke, PhD  "When we see a behavior that is problematic or confusing, the first question we should ask isn't "How do we get rid of it?" but rather "What is this telling us about the child?" (MD 2019)  The opening chapter sets the stage for a quiet revolution in how we understand children who struggle. Dr. Mona Delahooke invites us to take a step back from the culturally and medically ingrained belief that children’s outward actions are reliable windows into their inner intentions - or what they really mean and want based on their actions. Instead, she asks, nay implores, us to adopt a more biologically accurate, compassionate, and clinically effective lens from which to view each child as they present themselves. Their behavior is communication from a developing nervous system striving for regulation and often stuck somewhere else, either frozen or in flight..... Dr. M

  7. 12/06/2025

    Dr. M’s SPA Newsletter Volume 15 Issue 28 – Feeding Infants

    Food in Infancy What do we know? "Humans are the only mammals who feed our young special complementary foods before weaning and we are the only primates that wean our young before they can forage independently. There appears to be a sensitive period in the first several months of life when infants readily accept a wide variety of tastes and this period overlaps with a critical window for oral tolerance. As a result, infants should be exposed to a wide variety of flavors while mother is pregnant, while mother is nursing and beginning at an early age. There also appears to be a sensitive period between 4 and 9 months when infants are most receptive to different food textures. There remains debate about when it is best to begin introducing solid foods into an infant's diet however, the available evidence suggests that provided the water and food supply are free of contamination, and the infant is provided adequate nutrition, there are no clear contraindications to feeding infants complementary foods at any age. There is emerging evidence that introduction of solid foods into an infant's diet by 4 months may increase their willingness to eat a variety of fruits and vegetables later in life, decrease their risk of having feeding problems later in life, and decrease their risk of developing food allergies, and the early introduction of solid foods into an infant's diet does not appear to increase their risk of obesity later in childhood." (Borowitz S. 2021) Food Introductions — What’s the best way to approach it? As infants begin the shift from exclusive milk feeding to solid foods, a range of opinions inevitably emerge on how to navigate that transition. It’s tempting to get lost in modern guidelines, but an anthropological lens is often more revealing. Long before the age of purées in jars and puffed snacks in canisters, human infants ate what their parents ate. It was delivered in whole-food form and mechanically softened by chewing, cooking, or crushing. These early first foods carried important evolutionary advantages...Plus a piece on Hell Yeh or No by Derek Sivers Enjoy, Dr. M

  8. 11/30/2025

    Dr. M’s Women and Children First Podcast #102: Jeremy Goldberg – Life Begins

    This weeks Guest is Dr. Jeremy Goldberg. He styles himself as a compassion cultivating day making change agent/empathy collecting not quitting word wizard/chief burrito appreciator aspiring to inspire/struggle overcoming ranter in charge/ferocious idealist/never giver upper/a love bombing kindness pirate. What he really does, in my mind, is write and teach the world to project love and kindness where it is not layered enough. On his website he writes: My mission is to make kindness cool, empathy popular, and compassion commonplace. As part of that purpose, I write articles, send emails, host retreats and workshops, give TEDx talks, coach clients, host a podcast, write books, and make spoken word poetry videos. My name is Jeremy, I founded Long Distance Love Bombs, and I am fucking stoked to meet you. Send me an email and let's get going: LongDistanceLoveBombs at gmail dot com. We breakdown words, relationship, connection and being happy in a world of silly tribal divisiveness! In this conversation we discuss his experience as a new father and the initiation of fatherhood. "I have been wiped out and annihilated by parenting and the initiation of fatherhood. Hands down, brutally, face dragged along the hot coals of the initiation...." There are so many real, honest, open truths dropped along the winding road of this discussion. If you are young and ready to understand the world of fatherhood, this is a conversation for you! Dr. M

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