IJGC conversations

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The International Journal of Gynecological Cancer (IJGC) conversations is a podcast that brings you the latest insights into gynecologic malignancies. Tune in to engaging conversations with leading experts as they explore innovative and timely topics shaping the field. Hosted by the Editor-in-Chief Dr. Pedro Ramirez and special guests, each episode offers a dynamic and educational experience designed for clinicians, researchers, and anyone passionate about advancing gynecologic cancer care. Subscribe today or stream on your favorite podcast platform. IJGC - https://www.sciencedirect.com/journal/international-journal-of-gynecological-cancer - proudly serves as the official journal of the International Gynecologic Cancer Society and the European Society of Gynaecological Oncology.

  1. 14H AGO

    Ribociclib Plus Letrozole in Recurrent Low-Grade Serous Carcinoma of the Ovary: GOG 3026

    In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez, is joined by Drs. Brian M. Slomovitz and David M. Gershenson to discuss Ribociclib Plus Letrozole in Recurrent Low-Grade Serous Carcinoma of the Ovary: GOG 3026.   Dr. Slomovitz is a Gynecologic Oncologist at Mount Sinai Medical Center in Miami Beach, Florida, and Professor of Obstetrics and Gynecology at the Wertheim College of Medicine at Florida International University. He is an internationally recognized leader in gynecologic oncology clinical trials, specifically in immunotherapy and novel biomarker therapeutics. He also is a leader in sentinel lymph node detection for gynecologic malignancies.   Dr. David M. Gershenson have been engaged in several aspects of clinical and translational research of rare ovarian cancers. In the 1980s, his focus was primarily on improving therapies for patients with malignant ovarian germ cell tumors and ovarian sex cord-stromal tumors. Since the late 1980s, his research has concentrated on women with serous borderline tumors and low-grade serous ovarian cancer. In collaboration with Dr. Elvio Silva, they described the clinical course of women with serous borderline tumors and peritoneal implants, some of whom subsequently developed low-grade serous ovarian cancer. In 2004, he was part of the MD Anderson team who transformed the field by defining the binary histologic grading system for serous carcinoma, subsequently adopted by the World Health Organization. Several observational cohort studies of low-grade serous carcinoma followed, documenting the indolent nature of this rare subtype reflected in its prolonged overall survival, its relative insensitivity to chemotherapy, the efficacy of endocrine therapy in multiple clinical settings, the role of neoadjuvant therapy, the role of secondary cytoreductive surgery, the efficacy of bevacizumab, and the identification of the MAP kinase signaling pathway’s role in its pathogenesis. During that period, he was also chairing the Gynecologic Oncology Group’s Rare Tumor Committee (2005-2018), which was developing clinical trials specifically for rare ovarian cancers, including low-grade serous carcinoma. Much of this work culminated in the publication of GOG 281/LOGS, a positive randomized phase 3 clinical trials of the MEK inhibitor, trametinib, compared to physician’s choice standard of care, published in The Lancet in 2022. Additional seminal publications in 2022 included identifying mutations in the MAP kinase signaling pathway as a major prognostic factor and providing preliminary evidence that treatment with contemporary postoperative therapy may be reducing relapse rates. Finally, he is the Co-Principal Investigator of two important clinical trials to define the optimal primary adjuvant therapy (NRG-GY-019) and to determine the efficacy of letrozole plus ribociclib in women with recurrent low-grade serous carcinoma (GOG 3026).

    35 min
  2. MAY 4

    Single-Port Robotic Surgery: Safety and Feasibility

    In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez, is joined by Lucia Ribero, Vanna Zanagnolo to discuss Single-Port Robotic Surgery: Safety and Feasibility.   Lucia Ribero, MD, is a gynecologist and postdoctoral research fellow in Gynecologic Oncology at the European Institute of Oncology (IEO) in Milan, Italy. She completed her medical training and residency in Obstetrics and Gynecology in Cordoba, Argentina. She is currently involved in clinical and translational research in gynecologic oncology. Her main areas of interest include ovarian and endometrial cancer, surgical oncology, and translational research in a multidisciplinary setting.     Dr. Vanna Zanagnolo is a distinguished Unit Director of Minimally-invasive and Robotic Gynecologic Cancer Surgery Unit in European Institute of Oncology (IEO) in Milan, Italy. She is an expert in the diagnosis and treatment of gynecological cancers, including endometrial, ovarian, cervical, vulvar, and vaginal tumors. She specializes in providing ultra-specialist, multidisciplinary care focused on achieving optimal patient outcomes. An alumna of the University of Brescia, Dr. Zanagnolo graduated in Medicine and Surgery and specialized in Gynecology and Obstetrics, earning cum laude honors for both degrees. Her academic and professional journey includes a prestigious research fellowship at Johns Hopkins University, where she conducted foundational studies in reproductive health. She attended the International Gyn Oncology fellowship at Ohio State University and the fellowship in Gyn Robotic Surgery at Mayo Clinic Scottsdale, AZ. With over 160 scientific publications to her name, Dr. Zanagnolo is a recognized leader in her field. She has held several prominent leadership roles and memberships in elite medical societies, notably serving as the President of the Society of European Robotic Gynaecological Surgery in 2023.

    33 min
  3. APR 28

    GLP1-Receptor Agonists in Endometrial Cancer

    In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez, is joined by Vivek Podder and Brian M. Slomovitz to discuss GLP1-Receptor Agonists in Endometrial Cancer.   Vivek Podder, MBBS, is an oncology research fellow at Mount Sinai Medical Center in Miami, where he works in gynecologic oncology with a focus on translational research and clinical trials. His work spans molecular oncology, precision medicine, and outcomes research, with an emphasis on translating genomic and metabolic insights into clinically relevant treatment strategies. His research focuses on obesity-associated cancers and the role of metabolic pathways in cancer progression and treatment response, including the potential application of GLP-1 receptor agonists in oncology. He has also contributed to molecular classification and therapeutic stratification in endometrial cancer, including work on homologous recombination deficiency, as well as immunotherapy rechallenge and chemotherapy-free treatment strategies in low-grade serous ovarian carcinoma. His work reflects a consistent effort to translate biological insights into clinical practice. Dr. Podder has authored over 120 peer-reviewed publications, book chapters, and conference abstracts, along with more than 200 evidence summaries, with over 33,500 citations. He has presented his work at major international oncology meetings, including ASCO, ESMO, and SNO. He has contributed to five editions of the First Aid for the USMLE Step 1 and Step 2 CK series, widely regarded as essential resources for medical trainees, and serves as an associate editor and peer reviewer for several leading journals. His work has been recognized internationally, including selection to Stanford University’s list of the world’s top 2% scientists.   Dr. Slomovitz is a Gynecologic Oncologist at Mount Sinai Medical Center in Miami Beach, Florida, and Professor of Obstetrics and Gynecology at the Wertheim College of Medicine at Florida International University. He is an internationally recognized leader in gynecologic oncology clinical trials, specifically in immunotherapy and novel biomarker therapeutics. He also is a leader in sentinel lymph node detection for gynecologic malignancies.

    39 min
  4. MAR 16

    Pembrolizumab and weekly paclitaxel for platinum-resistant ovarian cancer

    In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez, is joined by Drs. Robert Wenham and Angeles Alvarez Secord to discuss Pembrolizumab and weekly paclitaxel for platinum-resistant ovarian cancer.   Dr. Robert Wenham is a gynecologic oncologist and Chair of the Gynecologic Oncology Program at Moffitt Cancer Center.  Dr. Wenham has a strong interest in research and is a principal investigator for numerous clinical trials to improve cancer care for women.  His research activities include the use of novel drugs for the treatment of gynecologic cancers.  He has received the Molly Cade Ovarian Cancer Research Award from the Gynecologic Cancer Foundation.  Dr. Wenham enjoys the challenge of helping women with complex issues and the opportunity to offer them cutting-edge therapies, from the latest chemotherapy approaches to biologically targeted therapies, minimally invasive surgery, and clinical trials.  He is also an expert in pelvic exenteration surgery, a very complex operation that offers hope of a possible cure for certain patients with gynecologic cancer.  Clinically, he prefers a more collaborative approach where the patient plays an active role in decisions as he guides them through the pros and cons of their options.     Angeles Alvarez Secord, MD, MHSc, is a professor in the Division of Gynecologic Oncology, Department of Obstetrics & Gynecology, Duke University Heath System. She received her undergraduate degree with honors from Carroll College in Helena, Montana and graduated AOA with honors from the University of Washington School of Medicine in Seattle, Washington. Dr. Secord completed her residency in obstetrics and gynecology and her fellowship in gynecologic oncology at the Duke University Medical Center in Durham, North Carolina. Upon completing her fellowship in 2001, she joined the Division of Gynecologic Oncology at Duke. She is currently Director of Gynecologic Oncology Clinical Trials, Associate Director of Clinical Research, Gynecology Oncology, and one of the Principal Investigators for NRG Oncology at the Duke Cancer Institute. Dr. Secord serves on the GOG Foundation Board of Directors. She is passionate about mentoring the next generation of investigators and serves as the GOG Foundation Education and Mentoring Chair and the NRG Oncology Investigator and Career Development Committee Vice-Chair. Dr. Secord is a fellow of the American College of Obstetricians and Gynecologists and an active member of American Society of Clinical Oncology, American Gynecological & Obstetrical Society, Society of Gynecology & Oncology, and International Gynecologic Cancer Society as well as other professional organizations.

    44 min

Ratings & Reviews

5
out of 5
3 Ratings

About

The International Journal of Gynecological Cancer (IJGC) conversations is a podcast that brings you the latest insights into gynecologic malignancies. Tune in to engaging conversations with leading experts as they explore innovative and timely topics shaping the field. Hosted by the Editor-in-Chief Dr. Pedro Ramirez and special guests, each episode offers a dynamic and educational experience designed for clinicians, researchers, and anyone passionate about advancing gynecologic cancer care. Subscribe today or stream on your favorite podcast platform. IJGC - https://www.sciencedirect.com/journal/international-journal-of-gynecological-cancer - proudly serves as the official journal of the International Gynecologic Cancer Society and the European Society of Gynaecological Oncology.

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