MedEvidence! Truth Behind the Data

Dr. Michael Koren

Welcome to the MedEvidence! podcast, hosted by Dr. Michael Koren. MedEvidence, where we help you navigate the real truth behind medical research with both a clinical and research perspective. In this podcast, we will discuss with physicians with extensive experience in patient care and research. How do you know that something works? In medicine, we conduct clinical trials to see if things work! Now, let's get to the Truth Behind the Data. Contact us at www.MedEvidence.com

  1. Skin Deep: What's New in Treating Chronic Skin Conditions

    4d ago

    Skin Deep: What's New in Treating Chronic Skin Conditions

    Send us Fan Mail Dermatologist Dr. Michael Bernhardt joins Dr. Mitchell Rothstein to discuss the rapidly changing and improving world of chronic skin condition. The two doctors discuss the correlation between chronic skin conditions and allergies, and the role that inflammation play in both. The docs then dive deep into our inflammation system. This informs the next section of the podcast, where the Drs. Bernhardt and Rothstein talk about the landscape of chronic skin condition medications. They explain that these conditions had poor outcomes and ineffective medicines for decades, and that this picture has only changed in the last 4-5 years with new medications that work from the inside out instead of the outside in. They talk about new generations of medication that target the inflammatory signals themselves inside the body, showing rapid relief to otherwise untreatable conditions. They finish with a brief look at what is coming down the pipeline of clinical trials. Be a part of advancing science by participating in clinical research. Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com Listen on Spotify Listen on Apple Podcasts Watch on YouTube Share with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released. Follow us on Social Media: Facebook Instagram X (Formerly Twitter) LinkedIn Want to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.com Music: Storyblocks - Corporate Inspired Thank you for listening!

    38 min
  2. Look Earlier, Treat Earlier with the New 2026 Lipid Guidelines

    Jun 17

    Look Earlier, Treat Earlier with the New 2026 Lipid Guidelines

    Send us Fan Mail Nearly a decade after the last major cholesterol guidelines were released, the new 2026 Multi-Specialty Lipid Guidelines introduce significant changes in how cardiovascular risk is assessed and managed. In this episode, Albert Lopez, DO, FACP, FASPC, explains why LDL cholesterol treatment goals have returned, how newer markers such as ApoB and Lipoprotein(a) are reshaping risk assessment, and why earlier, more aggressive treatment may help reduce the world's leading cause of death, cardiovascular disease. Dr. Al Lopez, DO,  discusses the role of statins, non-HDL cholesterol, triglycerides, genetic cholesterol disorders, screening recommendations for children and older adults, and the importance of a team-based approach to prevention. Whether you're a healthcare professional or someone interested in protecting your heart health, this episode provides a practical overview of the latest evidence-based recommendations for preventing heart disease. Be a part of advancing science by participating in clinical research. Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com Listen on Spotify Listen on Apple Podcasts Watch on YouTube Share with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released. Follow us on Social Media: Facebook Instagram X (Formerly Twitter) LinkedIn Want to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.com Music: Storyblocks - Corporate Inspired Thank you for listening!

    12 min
  3. Diet Soda, Dementia & Forever Chemicals: What the Research Really Shows

    Jun 10

    Diet Soda, Dementia & Forever Chemicals: What the Research Really Shows

    Send us Fan Mail In this episode of MedEvidence, host Dr. Michael Koren speaks with epidemiologist Dr. Hannah Gardener about how everyday exposures may influence long-term health outcomes. Dr. Gardener shares her journey from neuroscience and epidemiology training at Harvard to her current work studying stroke, dementia, and environmental risk factors. She explains how personal life experiences sparked her interest in environmental health and led her to examine how early-life and daily exposures can shape disease risk across the lifespan. The conversation explores her research on diet soda consumption and its surprising associations with vascular outcomes, including stroke, heart disease, and cognitive decline. She breaks down what “prospective cohort studies” really mean and how to interpret findings without overgeneralizing results. The discussion then expands to PFAS, often called “forever chemicals”, which are widely used in consumer products and persist in the environment and human body. Dr. Gardener explains where these chemicals are found, what health effects have been observed in the research, and practical, evidence-based strategies individuals can use to reduce exposure. This episode offers a thoughtful, research-driven look at how environmental factors, diet choices, and chemical exposures intersect with long-term brain and cardiovascular health—and what can realistically be done today to reduce risk. Be a part of advancing science by participating in clinical research. Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com Listen on Spotify Listen on Apple Podcasts Watch on YouTube Share with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released. Follow us on Social Media: Facebook Instagram X (Formerly Twitter) LinkedIn Want to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.com Music: Storyblocks - Corporate Inspired Thank you for listening!

    35 min
  4. Nasal Polyps, Sleep, and Modern Sinus Care

    Jun 3

    Nasal Polyps, Sleep, and Modern Sinus Care

    Send us Fan Mail What do island-hopping physicians, aviation safety, sleep medicine, and nasal polyps have in common? Dr. Adam Shapiro. In this episode of the MedEvidence Podcast, Dr. Michael Koren sits down with ENT specialist and sleep medicine expert Dr. Adam Shapiro to discuss his remarkable career practicing medicine in the U.S. Virgin Islands, commuting between islands as a pilot, and helping aviation professionals manage fatigue-related health issues. The conversation then shifts to a practical masterclass on nasal polyps and sinus health. Dr. Shapiro explains what nasal polyps are, why they develop, how they affect breathing and sleep, and the latest minimally invasive treatment options available today. He also discusses the connection between nasal health, sleep apnea, chronic sinus problems, ear pressure issues, and overall quality of life. Whether you're struggling with chronic congestion, sleep problems, recurrent sinus infections, or simply curious about the latest advances in ENT care, this episode offers expert insights and evidence-based guidance. If you found this helpful, subscribe to MedEvidence and share the episode with someone who’s always congested. Be a part of advancing science by participating in clinical research. Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com Listen on Spotify Listen on Apple Podcasts Watch on YouTube Share with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released. Follow us on Social Media: Facebook Instagram X (Formerly Twitter) LinkedIn Want to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.com Music: Storyblocks - Corporate Inspired Thank you for listening!

    28 min
  5. Can Omega-3s Help Your Brain? What the Research Really Shows

    May 27

    Can Omega-3s Help Your Brain? What the Research Really Shows

    Send us Fan Mail What happens when a Harvard-trained psychiatrist follows the evidence beyond traditional medicine? In this episode of MedEvidence, Dr. Michael Koren sits down with Dr. Carol Locke, physician entrepreneur and Chief Science Officer of OmegaBrite, to explore her remarkable journey from psychiatry and academic research at Harvard’s McLean Hospital to pioneering evidence-based omega-3 innovation. Dr. Locke shares how clinical research into mood disorders led to surprising discoveries about omega-3 fatty acids, brain health, inflammation, stress response, and emotional resilience. Together, they break down the science behind omega-3 balance, the role of EPA and DHA, third-party testing, and what clinical trials reveal about omega-3 supplementation’s impact on mood, anxiety, inflammation, and overall wellness. You’ll also hear insights on physician entrepreneurship, innovation in nutraceutical science, and why evidence-based quality matters when choosing supplements. In this episode:  How omega-3s influence brain function and mood  The link between inflammation, stress, and mental health  What clinical trials reveal about omega-3 supplementation  Why supplement purity and testing matter  Emerging science on omega-3 delivery to the brain  Advice for physicians pursuing innovation Be a part of advancing science by participating in clinical research. Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com Listen on Spotify Listen on Apple Podcasts Watch on YouTube Share with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released. Follow us on Social Media: Facebook Instagram X (Formerly Twitter) LinkedIn Want to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.com Music: Storyblocks - Corporate Inspired Thank you for listening!

    32 min
  6. From Stage 4 to Survivor: How Clinical Trials Changed One Man’s Life

    May 20

    From Stage 4 to Survivor: How Clinical Trials Changed One Man’s Life

    Send us Fan Mail When T.J. Sharpe was diagnosed with stage 4 melanoma at just 37 years old, the statistics were devastating. With a newborn son, a two-year-old daughter, and limited treatment options available at the time, he faced a life-changing decision: pursue standard chemotherapy or take a chance on early immunotherapy clinical trials. In this powerful episode of the MedEvidence Podcast, cardiologist and medical researcher Michael Koren sits down with T.J. to discuss his remarkable journey from cancer recurrence and uncertainty to becoming a long-term survivor through groundbreaking clinical research. Be a part of advancing science by participating in clinical research. Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com Listen on Spotify Listen on Apple Podcasts Watch on YouTube Share with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released. Follow us on Social Media: Facebook Instagram X (Formerly Twitter) LinkedIn Want to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.com Music: Storyblocks - Corporate Inspired Thank you for listening!

    25 min
  7. What Happens When Fat Builds Up in the Liver? The Liver Fats Domino Effect.

    May 13

    What Happens When Fat Builds Up in the Liver? The Liver Fats Domino Effect.

    Send us Fan Mail Watch the recorded presentation of “The Liver Fats Domino Effect” featuring Dr. Mitchell Rothstein and Dr. Michael Koren. In this educational luncheon event, the speakers discuss how fatty liver disease can progressively worsen over time, from early fat accumulation in the liver to inflammation, fibrosis, cirrhosis, and, in severe cases, liver transplant. This presentation also explores: - Who may be at risk for fatty liver disease - The connection between liver health, obesity, and metabolic conditions - Why fatty liver disease is often called a “silent” condition - Current and emerging research treatments available in Jacksonville Whether you are interested in liver health, clinical research, or learning more about fatty liver disease, this recorded session provides valuable insight into one of the fastest-growing liver conditions worldwide. Be a part of advancing science by participating in clinical research. Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com Listen on Spotify Listen on Apple Podcasts Watch on YouTube Share with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released. Follow us on Social Media: Facebook Instagram X (Formerly Twitter) LinkedIn Want to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.com Music: Storyblocks - Corporate Inspired Thank you for listening!

    49 min
  8. The Vicious Cycle of Sleep Apnea and Weight Gain

    May 6

    The Vicious Cycle of Sleep Apnea and Weight Gain

    Send us Fan Mail Snoring might be the sound you notice, but the real danger of obstructive sleep apnea is what you don’t hear: your brain repeatedly yanking you out of deep sleep to keep you breathing, over and over, all night long. Dr. Mitchell Rothstein, a board-certified pulmonary and sleep medicine physician, joins us to give a clear update on what modern sleep medicine understands about sleep apnea and why it has become so widespread as BMI rises in the community.  If you found this helpful, subscribe, and share the episode with someone who wakes up exhausted. Be a part of advancing science by participating in clinical research. Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com Listen on Spotify Listen on Apple Podcasts Watch on YouTube Share with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released. Follow us on Social Media: Facebook Instagram X (Formerly Twitter) LinkedIn Want to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.com Music: Storyblocks - Corporate Inspired Thank you for listening!

    14 min
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Ratings & Reviews

5
out of 5
8 Ratings

About

Welcome to the MedEvidence! podcast, hosted by Dr. Michael Koren. MedEvidence, where we help you navigate the real truth behind medical research with both a clinical and research perspective. In this podcast, we will discuss with physicians with extensive experience in patient care and research. How do you know that something works? In medicine, we conduct clinical trials to see if things work! Now, let's get to the Truth Behind the Data. Contact us at www.MedEvidence.com

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