Neural Compass

Jimini Health
  • 5.0 (3)
  • MENTAL HEALTH

Welcome to Neural Compass, a new podcast from Jimini Health.We’re charting the future of mental and behavioral health - at the intersection of AI, psychiatry, neuroscience, and real-world clinical care.Hosted by Jimini’s own Mark Jacobstein, Neural Compass features honest, forward-thinking conversations with the leaders shaping what’s next - from healthcare executives to AI pioneers.Whether you’re building in this space, investing in it, or navigating it as a decision-maker, this podcast is your guide to the breakthroughs, challenges, and ideas defining the next era of care.Learn more: jiminihealth.com

  1. Why Healthcare, Ever the Tech Laggard, Finally Got the AI Memo, with Jacob Effron

    APR 7

    Why Healthcare, Ever the Tech Laggard, Finally Got the AI Memo, with Jacob Effron

    What if healthcare’s biggest AI breakthroughs aren’t about new science—but about finally fixing systems that were never built to scale?In this episode of Neural Compass, Jacob Effron, Managing Director at Redpoint Ventures, joins Jimini’s Mark Jacobstein to explore where AI is already delivering real value in healthcare—and where hype still outpaces reality. Drawing on his experience at Flatiron Health and as an investor across AI, enterprise software, and healthcare, Jacob discusses why healthcare has become one of the fastest-adopting AI verticals, how real-world data actually creates value, and why tools that reduce clinician burden can unlock entirely new patient experiences. They cover:Why healthcare has emerged as a leading AI adoption verticalLessons from Flatiron Health on real-world data and evidenceWhat makes ambient clinical documentation a true “wedge” productHow AI can empower patients—not just cliniciansWhat separates generational health tech companies from short-lived hypeLearn more: jiminihealth.com

    37 min
  2. Talking “Conversational Doorknobs” & Broken Science with the Funniest Man in Psychology, Adam Mastroianni

    MAR 18

    Talking “Conversational Doorknobs” & Broken Science with the Funniest Man in Psychology, Adam Mastroianni

    What if the hardest problems in psychology aren’t about data or statistics—but about how we talk, think, and decide what counts as truth?In this episode of Neural Compass, psychologist, writer, and internet favorite Adam Mastroianni joins Jimini’s Mark Jacobstein for a wide-ranging conversation about conversation itself. Drawing from experimental psychology, improv, and lived experience with anxiety and depression, Adam explores why good conversations feel rare, why science struggles to study the most important questions, and why mental health progress may require ideas that don’t fit into academic boxes. Along the way, he reflects on leaving academia, rethinking peer review, and what happens when you try to tell the truth instead of writing for journals. They cover:Why great conversations rely on “doorknobs,” not just questionsHow anxiety, status, and speed shape the way we talk to each otherWhat’s broken in modern science—and why legibility can be the enemy of discoveryWhy therapy works even when we don’t fully understand howHow imagining that “things could be better” fuels both progress and dissatisfactionLearn more: jiminihealth.com

    46 min
  3. Tech, AI, and the Future of Therapy, with Dr. Harry Ritter, Alma's CEO

    FEB 10

    Tech, AI, and the Future of Therapy, with Dr. Harry Ritter, Alma's CEO

    What if fixing mental healthcare isn’t about replacing clinicians—but finally giving them the systems they’ve always lacked?In this episode of Neural Compass, Dr. Harry Ritter, founder and CEO of Alma, joins Jimini’s Mark Jacobstein to explore how technology, insurance alignment, and new business models can unlock better mental health care at scale. Drawing on his experience as a physician, lawyer, and former Oscar Health executive, Harry explains why behavioral health has lagged in tech adoption, how the pandemic permanently reshaped care delivery, and why empowering independent clinicians may be the fastest path to access, quality, and sustainability. They cover:- Why behavioral health remained tech-averse for so long—and what changed- How Alma helps thousands of independent therapists accept insurance and scale- The hidden systems failures between payers, providers, and patients- Where AI can remove administrative burden without replacing clinicians- Why mental health may be the most powerful lever for preventive careLearn more: jiminihealth.com

    40 min
  4. Can Stress Rewire the Brain—Across a Lifetime? with Dr. Nikolaos Daskalakis

    JAN 6

    Can Stress Rewire the Brain—Across a Lifetime? with Dr. Nikolaos Daskalakis

    Why do some people emerge from trauma resilient, while others carry its effects for decades—or even generations?In this episode of Neural Compass, Harvard neuroscientist and psychiatrist Dr. Nikos Daskalakis joins Jimini’s Mark Jacobstein to unpack the biology of stress and PTSD. Drawing on decades of research spanning animal models, post-mortem human brain studies, and cutting-edge multi-omics, Dr. Daskalakis explains how genetics, early life stress, and later trauma interact to shape vulnerability, resilience, and mental health outcomes. The conversation explores how glucocorticoid signaling, immune–brain communication, and cell-type-specific transcriptional changes complicate our understanding of PTSD—and why simple, one-size-fits-all treatments continue to fall short.They cover:* The “three-hit” model of stress: genetics, early life experience, and adult trauma* Why cortisol and glucocorticoid signaling matter—but aren’t the whole story* What single-cell and multi-omic brain studies reveal about PTSD versus depression* The unresolved question of whether trauma can be biologically transmitted across generationsLearn more: jiminihealth.com

    42 min
  5. Can DNA Data Unlock the Next Era of Medicine? with Dr. Yaniv Erlich

    12/16/2025

    Can DNA Data Unlock the Next Era of Medicine? with Dr. Yaniv Erlich

    What if the answers to mental health, aging, and disease have been encoded inside us all along?In this episode of Neural Compass, geneticist and entrepreneur Dr. Yaniv Erlich joins Jimini’s Mark Jacobstein to explore how data science and molecular biology are converging to reshape precision medicine. Dr. Erlich discusses everything from decoding the human genome to stabilizing RNA for next-generation therapeutics. Along the way, he reflects on why psychiatric traits are highly heritable, what twin studies really reveal, and why biotech innovation moves at a very different pace than tech.They discuss:- How next-generation sequencing revolutionized the study of information in DNA- The unexpected link between genealogy databases and personalized medicine- Why stabilizing RNA could make genetic therapies last longer and work better- The genetics behind mental health—and what we still don’t understand about itLearn more: jiminihealth.com

    51 min
  6. Is this the "Century of the Brain"? with Greg Kubin & Matias Serebrinsky

    11/25/2025

    Is this the "Century of the Brain"? with Greg Kubin & Matias Serebrinsky

    What if the next breakthrough in mental health isn’t a molecule—but a mindset?In this episode of Neural Compass, PsyMed Ventures co-founders Greg Kubin and Matias Serebrinsky join Jimini’s Mark Jacobstein to trace their journey from tech founders to frontier investors betting on the brain. They share how personal experiences with therapy and psychedelics reshaped their view of healing, and why the future of mental health may depend on tools that don’t just treat illness—but expand human potential.They cover:- How psychedelics opened the door to a new kind of neuroscience investing- Why the “century of the brain” will blur the lines between treatment and enhancement- The business and ethical challenges of funding radical innovation- What flourishing—not just recovery—could look like in the decades aheadLearn more: jiminihealth.com

    44 min
  7. Are We Teaching AI to Care—or Just to Sound Like It? with Dr. Nick Haber

    11/11/2025

    Are We Teaching AI to Care—or Just to Sound Like It? with Dr. Nick Haber

    What happens when the tools we build to understand us start to change what it means to be human?In this episode of Neural Compass, Stanford’s Dr. Nick Haber—computer scientist, educator, and co-founder of the Autism Glass Project—joins Jimini’s Mark Jacobstein to explore how AI is entering some of the most human spaces: learning, emotion, and mental health.From wearable devices that help children with autism recognize emotion to new research on large language models in therapy, Dr. Haber examines both the promise and the peril of AI that seems to “care.”They cover:- How wearable AI helped children with autism connect through emotion recognition- Why today’s chatbots still miss critical signs of distress—and what that reveals about human empathy- How AI might train, not replace, the next generation of therapists- Why the line between assistive and autonomous AI may define the future of careLearn more: jiminihealth.com

    42 min
  8. What Does It Take To Reform Mental Health Care From The Inside Out? with Mike Kopko

    11/04/2025

    What Does It Take To Reform Mental Health Care From The Inside Out? with Mike Kopko

    In this episode of Neural Compass, Mike Kopko—CEO and co-founder of Pearl Health—joins Jimini’s Mark Jacobstein to explore how value-based care, provider enablement, and intelligent incentives could finally help us build the system we deserve.They cover:- Why physicians—not hospitals or payers—are the key to real health care transformation- How value-based care forces a shift from rear-view to windshield thinking- What makes primary care the most underleveraged force in the system- Why mental health interventions struggle for investment—and how to change that- The real promise of AI: getting the right care to the right person, at the right timeLearn more: jiminihealth.com

    39 min
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Ratings & Reviews

5
out of 5
3 Ratings

About

Welcome to Neural Compass, a new podcast from Jimini Health.We’re charting the future of mental and behavioral health - at the intersection of AI, psychiatry, neuroscience, and real-world clinical care.Hosted by Jimini’s own Mark Jacobstein, Neural Compass features honest, forward-thinking conversations with the leaders shaping what’s next - from healthcare executives to AI pioneers.Whether you’re building in this space, investing in it, or navigating it as a decision-maker, this podcast is your guide to the breakthroughs, challenges, and ideas defining the next era of care.Learn more: jiminihealth.com

Information

  • Creator
    Jimini Health
  • Years Active
    2025 - 2026
  • Episodes
    23
  • Rating
    Explicit
  • Copyright
    © 7f88e3f0-539b-11f1-bba4-859ee7e8e71f
  • Show Website
    Neural Compass