Peptides and Longevity: Redefining Aging and Transforming Health with Dr. Kent Holtorf

Kent Holtorf, MD
  • 4.2 (29)
  • HEALTH & FITNESS
  • UPDATED WEEKLY

Join Dr. Kent Holtorf as he explore groundbreaking science, innovative therapies, and the future of health and aging. In each episode, he dives deep into the world of peptides—potent molecules that regulate immune function, boost cellular regeneration and optimize metabolism. Through conversations with leading experts, Dr. Holtorf explains how peptides differ from traditional hormones, their role in reversing chronic illness, and their potential to enhance sleep, brain function, and overall vitality. https://holtorfmed.com/ https://integrativepeptides.com/

  1. 4D AGO

    The Forgotten Foundations of Healing

    Chronic illness doesn’t begin with a diagnosis. It begins with a story. In this episode of Peptides and Longevity, Michael Blake from Forgotten Formula explains how birth trauma, microbiome disruption, toxic exposure, infections, and unresolved trauma accumulate over a lifetime to drive autoimmunity, cancer, and metabolic breakdown. Michael Blake is the founder of Forgotten Formula and a leading voice in root-cause healing for chronic illness, autoimmunity, and cancer-related conditions. His work focuses on tracing disease back to early-life microbiome disruption, toxic exposure, infections, and nutrient depletion. Through a systems-based approach that integrates diagnostics, detoxification, nutrient restoration, and mind–body–spirit healing, Michael Blake helps practitioners and patients restore the conditions the body needs to heal itself. Website: https://www.forgottenformula.com/ LinkedIn: https://www.linkedin.com/in/michael-blake-742a8619b Holtorf Medical Group Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://holtorfmed.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/holtorfmed/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/holtorfmedicalgroup/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Kent Holtorf, MD YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UC0S6Kaa1V9-dfo2sPyZPT6A⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Produced by DrTalks ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drtalks.com/podcast-service/⁠

    26 min

  2. FEB 4

    Regeneration Requires Power, Not Hope

    Healing breaks down when the cell runs out of energy. In this episode of Peptides and Longevity, Dr. Drew Kidder explains why mitochondria drive peptide effectiveness, regeneration, and immune balance, and why real healing must begin at the cellular level. Dr. Drew Kidder is a clinical educator with CellCore Biosciences, where his work focuses on mitochondrial health, detoxification, and cellular regeneration. He specializes in helping practitioners understand how energy production, toxic burden, and cellular resilience shape healing outcomes. Dr. Kidder emphasizes restoring cellular charge so the body can repair, regenerate, and maintain balance at the most foundational level. Website: https://cellcore.com/ Instagram: https://www.instagram.com/drdrewkidder/ LinkedIn: https://www.linkedin.com/in/drandrewkidder Holtorf Medical Group Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://holtorfmed.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/holtorfmed/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/holtorfmedicalgroup/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Kent Holtorf, MD YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UC0S6Kaa1V9-dfo2sPyZPT6A⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Produced by DrTalks ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drtalks.com/podcast-service/⁠

    32 min

  3. JAN 28

    Why Every Organ Has Its Own Biological Age

    Aging isn’t just about getting older. It’s about what’s quietly breaking down underneath the surface. In this episode of Peptides and Longevity, Dr. Jeffrey Gladden explains how nervous system regulation, biological aging hallmarks, environment, and regenerative sequencing determine whether aging accelerates or becomes reversible. Dr. Jeffrey Gladden is a former interventional cardiologist and the founder of Gladden Longevity, where he focuses on precision longevity medicine and health optimization. With decades of experience, he applies a multi-system approach to aging that includes nervous system regulation, biological aging hallmarks, performance capacity, and environmental design. Dr. Gladden is the author of 100 Is the New 30 and hosts the Gladden Longevity Podcast. His work centers on helping individuals extend healthspan, restore resilience, and access regenerative strategies through intelligent sequencing and personalized care. Jeffrey Gladden, MD, FACC Website: https://gladdenlongevity.com/ Instagram: https://www.instagram.com/gladdenlongevity/ LinkedIn: https://www.linkedin.com/in/jeffrey-gladden-md-facc-489bb530/ 🎧 Gladden Longevity Podcast Cutting-edge conversations on extending healthspan and performance—where science meets practical strategies for living younger, longer, and stronger. Listen on Apple Podcasts Visit ⁠⁠⁠⁠⁠⁠⁠⁠www.integrativepeptides.com⁠⁠⁠⁠⁠⁠⁠⁠ and use the code PODLIFE to get 10% off your first purchase. Holtorf Medical Group Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://holtorfmed.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/holtorfmed/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/holtorfmedicalgroup/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Kent Holtorf, MD YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UC0S6Kaa1V9-dfo2sPyZPT6A⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Produced by DrTalks ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drtalks.com/podcast-service/⁠

    31 min

  4. JAN 21

    AI Brain Mapping Meets Functional Medicine

    You can look healthy and still feel broken inside. In this episode of Peptides and Longevity, Dr. Miles Nichols joins us to explain why trauma, chronic stress, and environmental illness reshape the brain and nervous system. Tune in to find out how advanced diagnostics, breathwork, and phased healing restore resilience and function. Dr. Miles Nichols is a physician at Medicine With Heart Clinic, where he focuses on whole-person healing that integrates mind, body, and spirit. His work centers on complex chronic illness, nervous system dysregulation, and environmentally acquired conditions, using advanced tools like AI brain imaging and gene expression testing to uncover hidden drivers of disease. He also trains clinicians through Mind Body Functional Medicine, helping providers deepen their clinical skills while staying connected to passion, purpose, and sustainable care. Dr. Miles Nichols, DAOM, MSOM, LAc Website: https://medicinewithheart.com/ Instagram: https://www.instagram.com/drmilesnichols/ LinkedIn: https://www.linkedin.com/in/drmilesnichols/ Visit ⁠⁠⁠⁠⁠⁠⁠www.integrativepeptides.com⁠⁠⁠⁠⁠⁠⁠ and use the code PODLIFE to get 10% off your first purchase. Holtorf Medical Group Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://holtorfmed.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/holtorfmed/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/holtorfmedicalgroup/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Kent Holtorf, MD YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UC0S6Kaa1V9-dfo2sPyZPT6A⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Produced by DrTalks ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drtalks.com/podcast-service/⁠

    1h 3m

  5. JAN 14

    Perimenopause Starts Earlier Than You Think

    Perimenopause can feel like your body and emotions have suddenly turned against you. In this episode of Peptides and Longevity, Dr. Jen Pfleghaar explains why progesterone declines first, why estrogen becomes erratic, and how stress, toxins, and insulin resistance can drive anxiety, weight gain, libido changes, and skin issues years before menopause. Jen Pfleghaar, DO, ABOIM Website: pflegmed.com/dr-jen Instagram: instagram.com/integrativedrmom LinkedIn: linkedin.com/in/drjenpfleghaar/ 🎧 The Integrative Health Podcast with Dr. Jen   Explore the root causes of fatigue, hormone imbalance, and chronic illness—with a functional medicine doctor who helps patients take their health back: Listen on Spotify Listen on Apple Podcasts Listen on Buzzsprout Listen on iHeart Radio Visit ⁠⁠⁠⁠⁠⁠www.integrativepeptides.com⁠⁠⁠⁠⁠⁠ and use the code PODLIFE to get 10% off your first purchase. Holtorf Medical Group Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://holtorfmed.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/holtorfmed/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/holtorfmedicalgroup/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Kent Holtorf, MD YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UC0S6Kaa1V9-dfo2sPyZPT6A⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Produced by DrTalks ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drtalks.com/podcast-service/⁠

    42 min

  6. JAN 7

    Why Your Supplements Aren’t Reaching Your Cells

    Did you know that most supplements never even make it into your cells? In this episode of Peptides and Longevity, Dr. Jeffrey Gross joins us to explain how plant-derived exosomes act as nature’s delivery system, dramatically improving how nutrients reach and support cellular function. Dr. Jeffrey Gross is a spinal neurosurgeon and regenerative medicine specialist with a background in molecular biology. After years of treating patients with limited options beyond surgery, he expanded his practice to include regenerative approaches focused on restoring cellular function. He is the founder of ReCELLebrate, a functional medicine practice that focuses on biohacking, regenerative medicine, and longevity to optimize health and slow aging at a cellular level. Dr. Jeff Gross, MD Website: ReCELLebrate.com Instagram: Instagram.com/recellebrate  LinkedIn: Linkedin.com/company/recellebrate Visit ⁠⁠⁠⁠⁠www.integrativepeptides.com⁠⁠⁠⁠⁠ and use the code PODLIFE to get 10% off your first purchase. Holtorf Medical Group Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://holtorfmed.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/holtorfmed/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/holtorfmedicalgroup/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Kent Holtorf, MD YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UC0S6Kaa1V9-dfo2sPyZPT6A⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Produced by DrTalks ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drtalks.com/podcast-service/⁠

    21 min

  7. 12/31/2025

    Why ‘Reduce Your Stress’ Is Terrible Advice

    Trauma doesn’t stay in the past. It changes how your brain and immune system respond. In this episode of Peptides and Longevity, Dr. Keesha Ewers joins us to discuss the different kinds of trauma and how perceived stress can mirror brain changes in PTSD. We also dive into why healing requires shifting the patterns of your nervous system. Dr. Keesha Ewers is a board-certified functional and Ayurvedic medicine practitioner, trauma-informed psychotherapist, Doctor of Sexology, and integrative family nurse practitioner with over three decades of clinical experience. She is the founder and medical director of the Academy for Integrative Medicine Health Coach Certification Program and a MAPS-certified MDMA-assisted psychotherapy therapist. After leading the HURT Study on unresolved trauma, Dr. Ewers developed the HURT Model and Freedom Framework, approaches she used to reverse her own autoimmune disease and now applies with patients worldwide. She is a sought-after speaker, a TEDx presenter, and the best-selling author of Solving the Autoimmune Puzzle, The Quick and Easy Autoimmune Paleo Cookbook, and Your Libido Story. Dr. Keesha Ewers Website: drkeesha.com Instagram: instagram.com/drkeeshaewers LinkedIn: linkedin.com/in/keeshaewers Visit ⁠⁠⁠⁠www.integrativepeptides.com⁠⁠⁠⁠ and use the code PODLIFE to get 10% off your first purchase. Holtorf Medical Group Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://holtorfmed.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/holtorfmed/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/holtorfmedicalgroup/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Kent Holtorf, MD YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UC0S6Kaa1V9-dfo2sPyZPT6A⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Produced by DrTalks ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drtalks.com/podcast-service/⁠

    50 min

  8. 12/24/2025

    How To Provide Custom Private Label Supplements To Your Patients (For Practitioners)​

    Most supplements fail not because they’re useless, but because they’re poorly made, underdosed, or mislabeled.  In this episode of Peptides and Longevity, Dr. Kent Holtorf speaks with Don Wiencek about private-label supplements, quality control, FDA pitfalls, and how doctors can create effective, ethical formulations their patients can trust. Don Wiencek is the founder and owner of Tru Body Wellness, a private-label dietary supplement company that partners with healthcare practitioners to create high-quality, customized formulations. He brings decades of experience as a president, CEO, and executive in product manufacturing, with a background in engineering and a master’s degree in business. Don has focused on helping doctors navigate formulation challenges, manufacturing quality, regulatory compliance, and labeling accuracy—allowing practitioners to confidently bring effective supplements to their patients while building sustainable, ethical practices. Website: trubodywellness.com/ LinkedIn: linkedin.com/in/donald-wiencek-4754b99/ Visit ⁠⁠⁠www.integrativepeptides.com⁠⁠⁠ and use the code PODLIFE to get 10% off your first purchase. Holtorf Medical Group Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://holtorfmed.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/holtorfmed/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/holtorfmedicalgroup/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Kent Holtorf, MD YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UC0S6Kaa1V9-dfo2sPyZPT6A⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Produced by DrTalks ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drtalks.com/podcast-service/⁠

    33 min
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4.2
out of 5
29 Ratings

About

Join Dr. Kent Holtorf as he explore groundbreaking science, innovative therapies, and the future of health and aging. In each episode, he dives deep into the world of peptides—potent molecules that regulate immune function, boost cellular regeneration and optimize metabolism. Through conversations with leading experts, Dr. Holtorf explains how peptides differ from traditional hormones, their role in reversing chronic illness, and their potential to enhance sleep, brain function, and overall vitality. https://holtorfmed.com/ https://integrativepeptides.com/

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