59 episodes

A resource for psychiatrists  interested in exploring the neuroscientific basis of psychiatric disorders, psychopharmacology, neuromodulation, and other psychiatric interventions, as well as discussions of pseudoscience, Bayesian reasoning, ethics, the history of psychiatry, and human psychology in general.This podcast is not medical advice.  It strives to be science communication.  Dr. O'Leary is a skeptical thinker who often questions what we think we know.  He hopes to open more conversations about what we don't know we don't know.Find transcripts with show-notes and references on each episodes dedicated page at psydactic.buzzsprout.com.You can leave feedback at https://www.psydactic.com.The visual companions, when available, can be found at https://youtube.com/@PsyDactic.

PsyDactic T. Ryan O'Leary

    • Science
    • 5.0 • 1 Rating

A resource for psychiatrists  interested in exploring the neuroscientific basis of psychiatric disorders, psychopharmacology, neuromodulation, and other psychiatric interventions, as well as discussions of pseudoscience, Bayesian reasoning, ethics, the history of psychiatry, and human psychology in general.This podcast is not medical advice.  It strives to be science communication.  Dr. O'Leary is a skeptical thinker who often questions what we think we know.  He hopes to open more conversations about what we don't know we don't know.Find transcripts with show-notes and references on each episodes dedicated page at psydactic.buzzsprout.com.You can leave feedback at https://www.psydactic.com.The visual companions, when available, can be found at https://youtube.com/@PsyDactic.

    WTF Cerebellum - Little Brain, Big Deal

    WTF Cerebellum - Little Brain, Big Deal

    I did not until recently even consider the cerebellum when thinking about psychiatric conditions, but the more I read, the more I wonder why the cerebellum is not considered a potential important player in nearly every psychiatric disorder. Although it can be said that all brain regions primarily function to make predictions, the cerebellum is especially active at refining impromptu predictions through short periods of time as sensory data changes to help us better navigate the world, n...

    • 32 min
    WTF - Thalamus

    WTF - Thalamus

    The thalami are bilaterally symmetrical structures in the subcortical part of the brain that are cradled by the basal ganglia. They are major hubs of pretty much everything your brain does and all of the sensory information coming into the brain with the exception of smell.More primitive models of the brain visualized it as a bunch of relatively isolated modules, each specialized to perform a single task when queried and able to send that information to wherever it should go. More...

    • 22 min
    Seroquel (Quetiapine) - Drugs, Sex, Money and Psychopharm

    Seroquel (Quetiapine) - Drugs, Sex, Money and Psychopharm

    In this episode, I discuss a medication that patients who saw a psychiatrist or their primary care provider between about 1997 and 2015 were very likely to find themselves prescribed. More recently, it has been taken down a notch or two on prescribers lists of preferred meds. This medication is quetiapine, marketed as Seroquel by AstraZeneca in the US. Whether you were diagnosed with schizophrenia, bipolar disorder, depression, anxiety, an eating disorder, insomnia, PTSD, bo...

    • 24 min
    In a Word - Confabulation

    In a Word - Confabulation

    This episode continues an intermittent series called “In a Word.” Past episodes have explored words like Akathisia, Dissociation, Perseveration, and even the difference between Impulsive and Compulsive. This episode explores Confabulation, including some of the brain circuits involved, and what might differentiate confabulation from other kinds of false or implanted memories or delusions.Please leave feedback at https://www.psydactic.com. References and readings (when available) a...

    • 14 min
    How guilty are adolescents for their crimes?

    How guilty are adolescents for their crimes?

    In 2012 the Supreme Court heard two related cases involving adolescents convicted of murder and sentenced to life in prison without parole because of mandatory minimum sentencing guidelines in their states. One of the boys, Evan Miller along with an accomplice, had beat a man unconscious with a baseball bat after a fight that ensued when the man awoke to find Miller robbing him. Miller and his friend then decided to set fire to the home to cover up the evidence. This resulte...

    • 29 min
    Serious Mental Illness in America with Dr. Zac Brooks

    Serious Mental Illness in America with Dr. Zac Brooks

    I am lucky today to be able to bring you an interview with Dr. Zac Brooks who is passionate about serious mental illness (SMI). “What is serious mental illness?” you might ask. That is one of the things we are going to discuss, and you may be surprised when Dr. Brooks explains how it was first formally defined. We also discuss the numerous ways the US has tried to reform how SMI is treated with variable results.Please leave feedback at https://www.psydactic.com. References a...

    • 45 min

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