Return on Health

Niko Hems and Miguel Medina

Health is full of strong claims, conflicting voices, and bold promises. Most people end up overwhelmed and unsure who to trust. Return on Health aims to bring clarity by listening to every side, asking hard questions, and keeping science and common sense at the center. Hosted by Niko Hems and Miguel Medina Stanivukovic, the podcast takes a clear look at longevity, prevention, performance, and the future of health. We invite researchers, founders, clinicians, skeptics, and innovators, then pressure-test their ideas. Some viewpoints will align. Others will clash. That is the point.

  1. Aug 9

    Cancer Scientist: What Actually Causes Cancer? (The Internet Got It Wrong)

    What if one of the most popular ideas about cancer is simply wrong? For years, social media has promoted the idea that cancer is primarily a metabolic disease - one that can be starved, hacked, or even reversed through diet. But cancer geneticist Dr Moritz Przybilla argues that decades of genomic research tell a very different story. In this episode of Return on Health, hosts Niko Hems and Miguel Medina explore why cancer is fundamentally a disease of DNA, why aging remains its greatest risk factor, what the evidence really says about ketogenic diets and sugar, and where cancer research is genuinely moving next. Moritz also explains why most people misunderstand cancer prevention, why early detection may save far more lives than chasing miracle cures, how healthy tissues quietly accumulate mutations throughout life, and why the future of cancer medicine may lie in predicting risk decades before a tumor ever appears. ━━━━👤 ABOUT THE GUEST━━━━━ Dr. Moritz Jakob Przybylla is a cancer researcher at the Wellcome Sanger Institute in Cambridge. His research focuses on cancer genomics, early cancer evolution, and developing new approaches for cancer risk prediction, prevention, and early detection. Alongside his research, Moritz is passionate about making cancer science accessible and combating misinformation with evidence-based education. ━━━━🎙️ ABOUT THE HOSTS━━━━ Niko HemsNiko Hems is a longevity expert and Head of Growth at YEARS, a company building a longitudinal, multi-modal health dataset to make prevention personal and data-driven. Miguel MedinaMiguel Medina is co-host of Return on Health, a podcast built on a simple idea: a system always produces the outcomes it's incentivized to produce - so if we want better health outcomes, we need better incentives. ━━━━⏱ CHAPTERS━━━━━ 00:00 The Biggest Cancer Myth 00:57 Meet Cancer Geneticist Dr. Moritz Gerstung 02:04 Why He Left The Lab To Build A Public Voice 07:58 What Cancer Actually Is (Explained Simply) 12:21 Can You Really Prevent Cancer? 15:32 Which Infections Increase Cancer Risk? 17:15 Driver vs Passenger Mutations Explained 19:57 Thomas Seyfried's Metabolic Theory Of Cancer 28:49 Do Ketogenic Diets Help Treat Cancer? 32:59 Are 60% Of Cancers Really Unpreventable? 41:18 Metformin, Aging & Cancer Prevention 43:07 If We Could Slow Aging, Would We Prevent Cancer? 46:14 The Most Overhyped Cancer & Longevity Trends 47:11 Which Cancer Screening Test Should You Actually Get? 48:16 Moritz's Dream Cancer Research Project 49:35 How Healthcare Should Change ━━━━━💡 KEY QUESTIONS ANSWERED━━━━━ • Is cancer really a genetic disease?• Is the metabolic theory of cancer supported by current evidence?• Can sugar actually "feed" cancer?• Does the ketogenic diet help treat cancer?• Why are around 60% of cancers currently unavoidable?• Why is aging the biggest risk factor for cancer?• What are driver mutations and passenger mutations?• Can we predict cancer decades before it develops?• Which cancer screening tests are actually worth doing?• What is the future of cancer prevention?• How should healthcare shift from treating disease to preventing it? ━━━━━━━━━━━━━━━ Connect with Moritz: Linkedin: https://www.linkedin.com/in/moritz-jakob-przybilla/?locale=en Instagram: https://www.instagram.com/dr.moritzprzy/?hl=en

  2. Jul 26

    You Can't Stop Aging! Here's What Actually Matters… | Prof. Suresh Rattan

    Most people think aging is a disease. Professor Suresh Rattan thinks that's one of the biggest misconceptions in modern medicine. The anti-aging industry has never been bigger. Every week there's a new supplement, a new biomarker, a new longevity protocol, or another promise that you can slow, reverse, or even cure aging. But after more than 40 years studying the biology of aging, Suresh has reached a very different conclusion. Aging isn't something to cure. It's something to understand. In this episode of Return on Health, hosts Niko Hems and Miguel Medina sit down with one of the world's leading biogerontologists to challenge everything we think we know about aging, longevity, and health. We explore why Suresh believes there are no genes programmed to make us age, why the anti-aging industry is selling false promises, what he really thinks about Bryan Johnson, David Sinclair, and longevity escape velocity, and why living well may matter far more than simply living longer. ━━━━━👤 ABOUT THE GUEST ━━━━━ Professor Suresh I.S. Rattan is one of the world's leading biogerontologists, with more than four decades of research into the biology of aging. He founded the Laboratory of Cellular Ageing at Aarhus University in Denmark, coined the term "gerontogenes", founded the journal Biogerontology, and has published hundreds of scientific papers exploring why we age and what healthy aging really means. His work challenges many of the assumptions driving today's longevity industry, arguing that aging is a natural consequence of life - not a disease to be cured. ━━━━━━🎙️ ABOUT THE HOSTS ━━━━━━ Niko Hems Niko Hems is a longevity expert and Head of Growth at YEARS, a company building a longitudinal, multi-modal health dataset to make prevention personal and data-driven. Miguel Medina Miguel Medina is co-host of Return on Health, a podcast built on a simple idea: a system always produces the outcomes it's incentivized to produce - so if we want better health outcomes, we need better incentives. ━━━━━⏱ CHAPTERS ━━━━━━ 00:00 Aging Is Not a Disease 01:39 Why the Longevity Industry Is Selling Products 03:32 Do We Actually Understand Aging? 08:40 Why Aging Isn't a Disease 18:22 The Truth About the Hallmarks of Aging 19:12 How Humans Already Doubled Their Lifespan 23:15 Bryan Johnson, David Sinclair & Living Forever 27:52 What Actually Helps You Age Better? 35:59 What Does It Really Mean to Be Healthy? 40:40 Why We Age in the First Place 48:05 Suresh's Definition of Health 57:26 Rapid Fire: Can Humans Reach 150? 58:08 The Best Form of Hormesis 1:02:07 How Healthcare Needs to Change ━━━━━💡 KEY QUESTIONS ANSWERED ━━━━ • Is aging really a disease? • Are there actually genes that make us age? • Why do we age if evolution favors survival? • Does the longevity industry focus on the wrong problem? • What does Suresh really think about Bryan Johnson, David Sinclair and longevity escape velocity? • Can supplements or biohacks meaningfully slow aging? • What is the real definition of health? • Why is hormesis one of the most important concepts in healthy aging? • Can humans realistically live to 150 years old? • How should healthcare shift from treating disease to promoting health? ━━━━━Connect with Professor Suresh Rattan LinkedIn: https://www.linkedin.com/in/suresh-rattan-7951804/

  3. Jul 10

    Longevity Expert: Everything We've Been Told About Living Longer Is Wrong

    Most people think longevity is about living longer. Dr. Jack Kreindler thinks that's exactly where we've gone wrong. The longevity industry has never been bigger. Every week there's a new supplement, a new biomarker, a new biohack, or a new promise that you can slow aging. But after more than 25 years working with elite athletes, founders, CEOs and patients facing life-threatening disease, Jack has reached a very different conclusion. The goal isn't to live longer. It's to stay fully alive for as long as possible. In this episode of Return on Health, hosts Niko Hems and Miguel Medina sit down with one of the world's leading physicians in preventive medicine and human performance to separate evidence from hype. We explore why Jack has become one of the biggest critics of the word longevity, what he really thinks about Bryan Johnson and David Sinclair, whether NAD boosters actually make sense, and why purpose, relationships and resilience may be more powerful than the latest biohack. ━━━━━👤 ABOUT THE GUEST━━━━━ Dr. Jack Kreindler is a physician, physiologist and entrepreneur specializing in preventive medicine, human performance and healthy aging. He is the Founder & CEO of WellFounded and previously founded the Centre for Health and Human Performance (CHHP) in London, where he pioneered a model combining elite sports science with clinical medicine. Over the past two decades, he's worked with Olympic athletes, military personnel, founders, CEOs and patients with complex medical conditions - helping them maximize health, performance and resilience rather than simply adding years to life. ━━━━━🎙️ ABOUT THE HOSTS━━━━━━ Niko Hems Niko Hems is a longevity expert and Head of Growth at YEARS, a company building a longitudinal, multi-modal health dataset to make prevention personal and data-driven.  Miguel Medina Miguel Medina is co-host of Return on Health, a podcast built on a simple idea: a system always produces the outcomes it's incentivized to produce - so if we want better health outcomes, we need better incentives.  ━━━━━━CHAPTERS━━━━━━ 00:00 Why Jack Rejects the Word "Longevity" 01:33 What People Are Really Asking For 03:29 Healthspan vs. Lifespan 08:42 The Pillars That Actually Matter 12:02 What Happens Inside a Longevity Clinic 17:56 The Biomarkers Worth Paying Attention To 19:45 Why Human Connection Might Be the Ultimate Biomarker 28:25 Environmental Toxins & Modern Living 32:50 Are Toxins Really Making Us Sick? 36:14 Bryan Johnson, David Sinclair & Longevity Escape Velocity 40:03 What Founders Can Learn From Elite Performers 44:06 Burnout, Stress & High Performance 47:27 Can We Really Make 90 the New 60? 48:30 The Longevity Supplement Jack Would Never Take 49:40 The Supplements He Actually Recommends 51:15 Will AI Replace Doctors? 52:51 The Biggest Problem With Modern Healthcare ━━━━━💡 KEY QUESTIONS ANSWERED━━━ • Is the longevity industry focusing on the wrong goal? • Can you actually extend your lifespan - or just your healthspan?• Are expensive longevity supplements worth the money? • What does Jack really think about Bryan Johnson's Blueprint? • Which supplements have the strongest evidence today? • Why is VO₂ Max one of the most powerful predictors of long-term health? • Are environmental toxins a bigger problem than we realize? • Can AI become a better doctor than humans? • Why might relationships, purpose and meaning outperform the latest biohacks? • What would Jack change about modern healthcare if he could? Connect with Jack 🌐 WellFoundedhttps://wellfounded.health 🏥 Centre for Health and Human Performance (CHHP)https://chhp.com 💼 LinkedInhttps://www.linkedin.com/in/jackkreindler/

  4. Jun 29

    Best Selling Author: This Diet Will Betray You!

    Is the longevity supplement hype real - or are you wasting money? Bestselling author Bas Kast breaks down what actually works in nutrition, supplements, and slow aging. Most people don't suffer from a lack of health advice. They suffer from too much of it. One expert says eat more protein, the next says cut animal foods. One says supplements are useless, the next sells a 100-pill longevity stack - and all of it sounds convincing. In this episode of Return on Health, hosts Niko Hems and Miguel Medina sit down with Bas Kast - the science author whose book The Diet Compass (Der Ernährungskompass) sold over 1 million copies - to separate evidence from noise. We cover what still holds up in nutrition science, which supplements are worth taking (and which are pure marketing), why you are never the "average" person in a study, and Bas's new project SlowAger. ━━━━━━━━━━━━━━━ 👤 ABOUT THE GUEST ━━━━━━━━━━━━━━━ Bas Kast is a science journalist and bestselling author known for translating complex nutrition and longevity research for a general audience - without academic jargon or wellness hype. His book "The Diet Compass" (Der Ernährungskompass) became an international bestseller with 1M+ copies sold, grounded in thousands of peer-reviewed studies. His newer work focuses on vitamins and supplements (the "Vitamin Compass" / Der Vitamin-Kompass), and his current project, SlowAger, explores the messy intersection of nutrients, supplements and healthy aging. ━━━━━━━━━━━━━━━ 🎙️ ABOUT THE HOSTS ━━━━━━━━━━━━━━━ Niko Hems is a longevity expert and Head of Growth at YEARS, a company building a longitudinal, multi-modal health dataset to make prevention personal and data-driven. Miguel Medina is co-host of Return on Health, a podcast built on a simple idea: a system always produces the outcomes it's incentivized to produce - so if we want better health outcomes, we need better incentives. ━━━━━━━━━━━━━━━ ⏱️ CHAPTERS ━━━━━━━━━━━━━━━ 00:00 Too much health advice — the real problem with health information 01:18 How Bas Kast got into nutrition: headaches, low-carb & a personal wake-up call 05:15 Where health communication goes wrong: incentives & the Brian Johnson effect 12:19 The 3 principles of healthy eating (Michael Pollan's rule explained) 15:04 What Bas changed his mind on: whole grains, the gluten myth, cheese & intermittent fasting 21:01 Population data vs. personalization: why nutrition averages mislead you 28:28 A data-driven future for nutrition, CGMs & the 10-year Diet Compass update 33:25 The supplement hype: do we really need supplements? (NMN, NR, spermidine, taurine) 44:48 SlowAger, low-dose lithium & how to weigh risk vs. caution 51:06 Lightning round: 3 steps to use supplements intelligently 52:39 The most underrated supplement category (AREDS, lutein & zeaxanthin for eye health) 57:20 Return on Health: the one thing to fix in medicine — treat your body like your teeth ━━━━━━━━━━━━━━━ 💡 KEY QUESTIONS ANSWERED ━━━━━━━━━━━━━━━ - Do longevity supplements like NMN, NR and spermidine actually work? - What are the 3 simple rules for a healthy diet? - Is gluten bad for you if you're not sensitive? - Why does the same diet work for one person and fail for another? - Which supplements are actually backed by strong evidence? - Is low-dose lithium safe as a supplement? - Why is the medical system "too reactive" — and how do we fix it? ━━━━━━━━━━━━━━━ 🔗 LINKS ━━━━━━━━━━━━━━━ 📚 Bas Kast - The Vitamin Compass: https://vitaminkompass.com/ 🔔 Subscribe for a new episode every week

  5. May 31

    Functional Medicine MD: What 5,000+ Patients Taught Him About Root Cause Medicine

    Functional Medicine MD: What 5,000+ Patients Taught Him About Root Cause Medicine In this episode of Return on Health, we speak with Dr. Peter Martin, physician, former CNS pharmacology researcher, and founder of FunMed, one of Europe’s leading functional medicine clinics. Peter spent around 15 years in pharmacology research before his own burnout pushed him to look beyond the conventional model of symptom control. What started as a personal search for recovery became a data-driven clinical model built around root cause medicine, extensive biomarker testing, gut health, metabolism, and chronic disease prevention. We talk about what functional medicine actually means, why chronic disease often needs a different care model, and what Peter has learned from treating more than 5,000 patients. He explains why fasting insulin may be one of the most overlooked markers in modern healthcare, how low-grade inflammation is often connected to gut health, and why normal lab results do not always mean someone is truly healthy. We also get into the controversial parts: large biomarker panels, false positives, red meat, vegan diets, anti-nutrients, carnivore diets, and the weakness of much nutrition research. Peter also shares why he believes functional medicine could become part of the European healthcare system, especially if reimbursement shifts from visits and procedures toward actual health outcomes. This episode covers: What 5,000+ patients taught him Why fasting insulin is often missed How root cause medicine could change care Topics discussed: 00:00 Introduction 01:00 What FunMed does differently 02:00 Real-world data from 5,000+ patients 03:30 From CNS pharmacology to functional medicine 07:00 Root cause medicine vs symptom control 10:30 Precision health in Sweden and Germany 15:30 Why FunMed tests around 200 biomarkers 21:00 False positives and the problem with large panels 28:00 Fasting insulin and insulin resistance 31:00 Low-grade inflammation and gut health 35:30 Low-carb and ancestral nutrition 41:00 Vegan diets, nutrient deficiencies, and bio-individuality 49:30 Red meat, nutrition research, and epidemiology 56:00 Functional medicine and insurance coverage 59:00 Rapid fire: biomarkers, magnesium, carnivore diet, healthcare reform Guest Dr. Peter Martin Physician, former CNS pharmacology researcher, founder of FunMed, and one of the leading voices trying to bring functional medicine and precision health into European healthcare. Guest links LinkedIn: https://www.linkedin.com/in/peter-martin-31b23342/ FunMed: https://www.funmed.se/?srsltid=AfmBOorlgUNnEK1ba7p_zIxug35sx3YMSq6PmYiufq6xJH1VAQ-EiQc0 Return on Health is available wherever you get your podcasts. If you enjoyed this episode, leaving a 5-star rating on Spotify helps us bring more honest conversations about health, longevity, and medicine to more people.

    Functional Medicine MD: What 5,000+ Patients Taught Him About Root Cause Medicine
  6. May 6

    Harvard MD: The Truth About Peptides And Longevity Medicine

    Harvard MD: The Peptide Boom Is Here.. But Is Medicine Ready? In this episode of Return on Health, Niko and Miguel speak with Dr. Anand Vinjamoori, Harvard Medical School and Harvard Business School trained physician, former founding Chief Medical Officer at Modern Age, advisor to Superpower, and founder of Next Generation Medicine. Together, they discuss why longevity medicine is booming while many companies still struggle to build sustainable businesses, why peptides may become one of the next major waves in health optimization, and why the future of biomarkers will likely require a much more individualized and data-driven approach. This episode covers: The peptide boom and why it mattersWhy longevity businesses often failWhat biomarkers can and cannot tell us Dr. Anand explains why the current medical evidence system may be too slow for the next generation of therapies, how real-world data and patient registries could help close the evidence gap, and why biomarkers should be used with nuance rather than treated as absolute truth. He also shares his view on overhyped interventions, the role of exercise, and the cultural differences between American optimization culture and European lifestyle rhythms. Key topics Longevity medicine and market timingThe business challenges behind longevity clinicsCustomer acquisition and why messaging mattersThe rise of peptides in health optimizationEvidence gaps, real-world data, and patient registriesPersonalized medicine and individual risk assessmentBiomarkers, multi-omics, and biological individualityWhy HBA1c can be overinterpretedExercise as one of the strongest health interventionsCold plunges and the problem of overapplied hormesisEuropean lifestyle culture vs. American optimization culture Chapters 00:00 The Longevity Paradox01:03 Building Modern Age and the Early Longevity Market05:04 Personal Motivations Behind Longevity Medicine07:57 What Patients Actually Want From Longevity Care11:39 Why Many Longevity Businesses Struggle15:12 How Customer Preferences Have Changed18:21 Peptides as the Next Big Wave19:07 Peptides, Regulation, and Medical Experimentation24:24 The Evidence Gap in Peptide Use30:58 Why Medicine Needs Better Risk Assessment36:59 Biomarkers and Biological Ground Truth44:20 Multi-Omics and the Future of Measurement48:35 Which Biomarkers Are Useful — And Which Are Noise?52:42 Culture, Lifestyle, and Health Optimization55:45 Lightning Round: Metrics, Interventions, and Healthcare Reform Guest Dr. Anand VinjamooriHarvard Medical School and Harvard Business School trained physician, former founding Chief Medical Officer at Modern Age, advisor to Superpower, and founder of Next Generation Medicine. Guest links LinkedIn: https://www.linkedin.com/in/vinjamoori/Next Generation Medicine: https://www.nextgenerationmedicine.co/Superpower: https://www.linkedin.com/company/superpower/posts/?feedView=all Listen now Return on Health is available wherever you get your podcasts. If you enjoyed this episode, leaving a 5-star rating on Spotify helps us bring more honest conversations about health, longevity, and medicine to more people.

    Harvard MD: The Truth About Peptides And Longevity Medicine
  7. Apr 19

    Geriatrician: Most Aging Is Preventable (But We Start Too Late)

    Most people think aging is something that happens later. In reality, the processes that determine how you age — and whether you stay functional — start decades earlier. In this episode of Return on Health, we sit down with Roberta Vella Azzopardi, a geriatrician and geroscientist with a PhD in cognitive frailty, to break down what aging actually looks like in clinical practice. Instead of focusing on single diseases, this conversation zooms out: Why do people lose independence? What really drives decline? And where are the biggest missed opportunities in prevention? What this episode covers Why modern medicine often intervenes too lateWhat frailty really means — and why it matters more than ageHow loss of muscle drives metabolic and cognitive declineThe concept of peak span and why function beats lifespanWhy hearing loss is one of the biggest overlooked dementia risk factorsThe massive gap in menopause and women’s health careWhat actually works vs. what’s just hype in longevityKey takeaways Frailty is best understood as loss of physiological reserves.When those reserves drop below a certain threshold, even small stressors can lead to long-term decline. This is why two people at the same age can look completely different clinically — one independent, one dependent. A major driver of this process is muscle loss.Muscle is not just about movement. It directly affects metabolic health, insulin sensitivity, and even brain function. The good news: even later in life, resistance training and sufficient protein intake can still improve outcomes. One of the most underestimated risk factors discussed in this episode is hearing loss.It contributes to cognitive decline through increased cognitive load, social isolation, and shared vascular mechanisms — yet remains widely underdiagnosed and undertreated. Another critical blind spot is women’s health, especially around menopause.Many symptoms are treated in isolation instead of addressing underlying hormonal changes, leading to years of missed intervention opportunities. Timestamps (00:00) Introduction & Roberta’s background(04:30) Frailty explained: vulnerability vs. age(11:00) Why prevention starts decades earlier(16:50) Reversing decline: muscle, protein, training(21:00) Peak span vs. lifespan(28:30) Menopause and missed diagnoses(36:30) Dementia prevention & modifiable risks(37:00) Hearing loss and cognitive decline (50:00) Busting common aging myths(55:00) Lightning round insights Takeaways Start investing in your health early — not when problems appearMaintain muscle mass through resistance training and protein intakeDon’t ignore hearing health — it directly impacts brain healthLook at root causes, not isolated symptomsPrevention is not one intervention — it’s a systemRoberta:https://www.linkedin.com/in/roberta-vella-azzopardi-md-phd-8235878a/ Return on Health:https://returnonhealth.de/ Niko:https://www.linkedin.com/in/niko-hems/https://www.instagram.com/niko_hemshttps://nikohems.de/ Miguel:https://www.linkedin.com/in/miguel-medina-stanivukovic-857b9720b/https://www.instagram.com/miguelmedinastanivukovic/?hl=en

    Geriatrician: Most Aging Is Preventable (But We Start Too Late)
  8. Apr 4

    Karolinska MD PhD: The Hidden Phase Before Disease

    Karolinska MD PhD: You Feel Healthy. Your Data Disagrees Most people think they’re healthy. But biology doesn’t care how you feel. Long before symptoms show up, your physiology is already shifting.. and most check-ups won’t catch it. In this episode, we sit down with Natalia Trpchevska (MD, PhD Karolinska, Medical & Scientific Director at AYUN) to break down what longevity medicine actually looks like when applied properly. We go beyond surface-level optimization and talk about what actually drives risk: mitochondria, metabolic flexibility, genetics, and why most people are already off track without knowing it. This episode covers: Why longevity medicine still struggles in practiceMitochondria, NAD+ and optimization mythsBiohacking and the future of healthcare Key takeaways: Health declines silently — symptoms come lateLongevity medicine asks: where are you heading biologically?The basics still dominate outcomes — most people underestimate themThe next level is personalization, not more hacksTwo “healthy” people can have completely different risksMitochondria adapt first — then they start driving dysfunctionMost mitochondrial interventions are misunderstoodGenetics gives probabilities, not certaintyReal optimization = prioritization + sequencing About Natalia: Natalia Trpchevska is a medical doctor and holds a PhD in genetics from the Karolinska Institutet. She is the Medical & Scientific Director at AYUN in Zurich, where she focuses on applying systems biology and layered diagnostics to detect early shifts in physiology — before disease develops. Her work bridges clinical medicine and research, with a strong emphasis on translating complex biology into actionable interventions. Timestamps: 00:00 – Introduction & Natalia’s background (Karolinska, genetics → clinic)03:30 – Why genetics naturally leads into longevity medicine05:00 – What longevity medicine actually does differently07:30 – “Physiology before pathology” explained09:30 – The basics vs. the real next level11:30 – Same lifestyle, completely different risk profiles13:30 – APOE4, Lp(a) and personalized strategy15:00 – Mitochondria: what actually happens as you age18:30 – When mitochondrial dysfunction becomes clinically relevant21:00 – Cause vs. consequence: where mitochondria fit in aging23:30 – How mitochondrial function is actually measured26:30 – Why isolated tests don’t work (layered diagnostics)29:00 – What happens after testing: prioritization & sequencing32:00 – Why “doing everything” doesn’t work35:00 – IHHT explained: mechanism, benefits, limitations38:30 – Risks, contraindications & when it backfires41:00 – Environment vs. lifestyle: what really drives dysfunction44:00 – The hierarchy: metabolism → inflammation → toxins47:00 – Why most people focus on the wrong layer49:30 – What genetics got wrong over the last decade53:00 – Polygenic risk, probabilities & real-world use56:00 – Gene–environment interaction: what actually matters58:30 – Final thoughts: what people still misunderstand about health Links: Natalia:https://www.linkedin.com/in/natalia-trpchevska/https://www.ayun.ch/ More about Return on Health:https://returnonhealth.de/ Niko:https://www.linkedin.com/in/niko-hems/https://www.instagram.com/niko_hemshttps://nikohems.de/ Miguel:https://www.linkedin.com/in/miguel-medina-stanivukovic-857b9720b/https://www.instagram.com/miguelmedinastanivukovic/

    Karolinska MD PhD: The Hidden Phase Before Disease

About

Health is full of strong claims, conflicting voices, and bold promises. Most people end up overwhelmed and unsure who to trust. Return on Health aims to bring clarity by listening to every side, asking hard questions, and keeping science and common sense at the center. Hosted by Niko Hems and Miguel Medina Stanivukovic, the podcast takes a clear look at longevity, prevention, performance, and the future of health. We invite researchers, founders, clinicians, skeptics, and innovators, then pressure-test their ideas. Some viewpoints will align. Others will clash. That is the point.

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