The Ongoing Transformation

Issues in Science and Technology

The Ongoing Transformation is a biweekly podcast featuring conversations about science, technology, policy, and society. We talk with interesting thinkers—leading researchers, artists, policymakers, social theorists, and other luminaries—about the ways new knowledge transforms our world. This podcast is presented by Issues in Science and Technology, a journal published by Arizona State University and the National Academies of Sciences, Engineering, and Medicine. Visit issues.org and contact us at podcast@issues.org.

  1. Making Sure Open Science Stays Open

    1d ago

    Making Sure Open Science Stays Open

    There was a time when everything on the internet seemed like it would be there forever, whether a Facebook status or a government website. But today the prospect of maintaining massive amounts of digital history is in doubt. This poses a particular issue for the open science movement, which has advocated for wide access to scientific data and papers over the last 25 years. The movement’s successes have led to the creation of digital research infrastructure such as data libraries and preservation systems that serve large and small research communities. Now, as the system is maturing, it’s becoming clear that open science isn’t free: it requires investment and significant effort to stay alive. Without it, open research cannot be verified or advanced.  On this episode, host Megan Nicholson is joined by Jen Gibson and Kaitlin Thaney, authors of “Who Will Keep Research Data Infrastructure Open and Running?” in our Spring 2026 issue. Gibson is the executive director of Dryad, an open-access international research data repository and curation service. Thaney is the executive director of Invest in Open Infrastructure, a nonprofit that advances open-source solutions and systems for research communities.  Resources: Read “Who Will Keep Research Data Infrastructure Open and Running?” for more on the importance of maintaining digital infrastructure. Visit Dryad and Invest in Open Infrastructure’s websites to learn more about open data, open infrastructure, and how you can support their work.

    38 min
  2. Edward You Protected America From Bioterror

    Mar 24

    Edward You Protected America From Bioterror

    On Science Policy IRL, we talk to people in science policy about what they do and how they got there. Most of the people we’ve interviewed work in the legislative branch of the federal government or in agencies in the executive branch. In this installment, we’re going to an unexpected place for science policy: the Federal Bureau of Investigation.  Host Lisa Margonelli is joined by Edward You, who has been called “America’s Top Bioterror Cop” by MIT Technology Review. A biochemist by training, You worked for the FBI for over 20 years. At the FBI, he served in the Weapons of Mass Destruction Directorate, and was also on joint duty assignment at the Office of the Director of National Intelligence, where he served as the National Counterintelligence Officer for Emerging and Disruptive Technologies. In this episode, Margonelli and You discuss how his time as an FBI agent enabled him to reframe the way the policymakers understand what is required to protect biosecurity and support innovation. Resources:  Watch a 60 Minutes episode on DNA and the big-money market for biodata, featuring Edward You.  Read “National and Transnational Security Implications of Big Data in the Life Sciences” (2014), a joint report from the FBI, American Association for the Advancement of Science, and United Nations Interregional Crime and Justice Research Institute.  Learn more about big data, security, and the FBI’s role by reading “Biosecurity in the age of Big Data: A Conversation With the FBI”.  Check out Issues’s recent publications on biosecurity:  Interview with Senator Todd Young on emerging biotechnologies. “Reconsidering Research Security” by John C. Gannon, Richard Meserve, and Maria T. Zuber.  “When All Research Is Dual Use” by Sam Weiss Evans.

    44 min
  3. Building a Tech Innovation Ecosystem in Newark

    Mar 3

    Building a Tech Innovation Ecosystem in Newark

    Innovation lately feels synonymous with the digital entrepreneurs of Silicon Valley or the high-tech corridor of Route 128 outside Boston. But when Thomas Edison opened his first research lab in the 1870s, it was in Newark, New Jersey. A few years later, in nearby Menlo Park, he invented the light bulb. Now, Newark is working to build a new, inclusive tech innovation ecosystem that goes beyond this legacy. On this episode, host Lisa Margonelli is joined by Fay Cobb Payton and Lyneir Richardson, who are both at Rutgers University. Payton directs the Institute for Data, Research, and Innovation Science (IDRIS) and Lyneir is the executive director of the Center for Urban Entrepreneurship and Economic Development. Together they have been pioneering data-led innovation and business accelerators with a diverse group of entrepreneurs. Resources Read Senator Andy Kim’s vision for New Jersey’s Einstein Corridor.  Learn more about the Exit to Win accelerator by watching this video.  Check out more Issues articles on regional economic development.  “Cultivating Mastery in Place” by Maryann Feldman and Alaina Kayaani-George. Diné entrepreneurs entwine economic renewal with mutual obligation, providing a model of regional economic development that serves the community.“Revisiting the Connection Between Innovation, Education, and Regional Economic Growth” by Grace J. Wang. What have we learned over the past 40 years about how to generate sustained economic growth through scientific research and technological innovation?“Place-Based Economic Development” by Maryann Feldman. “Lessons from Baltimore for Participatory Research” by Alvin Hathaway Sr. A pastor and community organizer explains what a landmark Black neuroscience study needed to gain insight, influence, and credibility.

    33 min

Ratings & Reviews

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out of 5
22 Ratings

About

The Ongoing Transformation is a biweekly podcast featuring conversations about science, technology, policy, and society. We talk with interesting thinkers—leading researchers, artists, policymakers, social theorists, and other luminaries—about the ways new knowledge transforms our world. This podcast is presented by Issues in Science and Technology, a journal published by Arizona State University and the National Academies of Sciences, Engineering, and Medicine. Visit issues.org and contact us at podcast@issues.org.

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