Tick Boot Camp

Matt Sabatello and Rich Johannesen

The goal of the Tick Boot Camp Podcast is to help people liberate themselves and others from suffering caused by Lyme disease through validation, community building, belief that healing is possible, and modeling success. Listen to our Tick Boot Camp podcast using all major podcast streaming services such as Apple Podcasts, Spotify, and YouTube Music. Our podcast is also integrated with smart home devices, such as Amazon Alexa and Apple TV. Ask your device to "play the Tick Boot Camp Podcast!"

  1. 7h ago

    From Alpha-Gal to Lyme: Erin Oprea on Elite Fitness, Military Leadership, and Advanced Healing with Peptides & Integrative Medicine

    In this powerful episode of the Tick Boot Camp Podcast, we sit down with Erin Oprea—elite fitness trainer, U.S. Marine Corps veteran, and Lyme disease warrior. Known for training celebrities like Carrie Underwood, Erin shares her journey from peak physical performance to battling chronic illness—and how she fought her way back using cutting-edge therapies, peptides, and integrative medicine. Erin also reflects on her groundbreaking military career, including making history as the leader of the first all-female platoon attached to the infantry in a war zone, and how that same resilience now fuels her healing journey. Erin Oprea’s Background U.S. Marine Corps veteran with two tours in Iraq Led the first female platoon attached to infantry in a combat zone Elite celebrity trainer, including Carrie Underwood Built a career around peak physical performance and discipline Lyme Disease & Alpha-Gal Journey Experienced unexplained symptoms despite elite fitness level Faced delayed recognition and diagnosis Developed Alpha-Gal syndrome, a tick-borne allergy to mammalian meat Shifted toward functional and integrative medicine approaches Combined performance mindset with advanced healing protocols Advanced Treatments & Therapies HBOT (Hyperbaric Oxygen Therapy) for oxygenation, inflammation reduction, and tissue healing EBOO₂ (Extracorporeal Blood Oxygenation and Ozonation) for pathogen reduction and blood detoxification HOCATT (Hyperthermic Ozone and Carbonic Acid Transdermal Technology) for full-body detox and immune support Hydrogen Therapy to reduce oxidative stress and support mitochondrial health SAAT (Soliman Auricular Allergy Treatment) to help reset immune response related to Alpha-Gal Herbal protocols for antimicrobial support, detoxification, and immune modulation Peptide Therapy Protocol Guided by experts like Dr. Joe Phiakhamta and informed by The Complete Guide to Peptides: Unlocking the Secrets to Health, Healing, and Longevity, Erin incorporated advanced peptide therapy: LL-37 to target bacteria, viruses, and biofilms including Lyme pathogens Thymosin Alpha-1 (TA-1) to regulate and strengthen immune response BPC-157 to repair gut lining, reduce inflammation, and accelerate tissue healing TB-500 (Thymosin Beta-4) to promote recovery, reduce inflammation, and support cellular repair SS-31 (Elamipretide) to improve mitochondrial function and energy production KPV to reduce inflammation and support gut and immune balance Key Practitioner Dr. Joe Phiakhamta specializing in peptide therapy and integrative Lyme disease treatment Focus on immune restoration, pathogen reduction, and performance recovery Fitness Meets Chronic Illness Recovery Transitioned from elite performance to chronic illness management Applied discipline and training mindset to healing process Leveraged advanced therapies to rebuild strength and energy Represents the intersection of fitness optimization and medical innovation Key Takeaways Tick-borne illnesses can impact even the most elite performers Alpha-Gal syndrome is a serious and often overlooked tick-borne condition Healing requires a multi-layered approach including immune, detox, and mitochondrial support Peptides are an emerging and powerful tool in Lyme disease recovery Mental resilience plays a critical role in long-term healing Final Thoughts Erin Oprea’s journey is a powerful example of resilience, innovation, and determination. From combat leadership to chronic illness recovery, she continues to push boundaries—showing what’s possible when elite discipline meets cutting-edge medicine.

    1h 49m
  2. Jun 13

    When Lyme Disease Steals Your Identity: How Poetry Helped Jasmin Perdomo Heal

    What happens when chronic Lyme disease takes away your health, your confidence, and even your sense of self? In this deeply emotional and inspiring episode of the Tick Boot Camp Podcast, Jasmin Perdomo shares her powerful 12-year journey through chronic Lyme disease, Bartonella, Babesia, debilitating neurological symptoms, medical gaslighting, emotional trauma, and ultimately — rediscovering herself through poetry, faith, and healing. Raised in New Jersey and once a hyper-athletic young woman, Jasmin never imagined she would one day become bedridden, unable to walk without holding onto walls, crawling from her bed to the bathroom, and searching desperately for answers no doctor seemed able to provide. But through unimaginable suffering came transformation. Jasmin opens up about: Living years undiagnosed with Lyme disease Severe neurological Lyme symptoms including vertigo, memory loss, facial paralysis, and heart complications The emotional toll of chronic illness and divorce Her experience with aggressive antibiotic protocols and Herxheimer reactions Why detoxification, nervous system healing, spirituality, and creativity became essential parts of her recovery How poetry became her lifeline during the darkest moments of her journey This conversation is raw, validating, and hopeful for anyone navigating Lyme disease, chronic illness, trauma, or identity loss. In This Episode You’ll Learn Jasmin’s Early Lyme Disease Symptoms Jasmin describes how unexplained fatigue, tachycardia, heart palpitations, vertigo, ringing in the ears, slurred speech, and neurological symptoms slowly overtook her life while living in Puerto Rico. The Reality of Medical Gaslighting Like many Lyme patients, Jasmin spent years searching for answers while being misdiagnosed, dismissed, and prescribed medications that failed to address the root cause of her illness. Chronic Lyme Disease and Emotional Trauma The episode explores the connection between stress, trauma, emotional suppression, nervous system dysregulation, and chronic illness progression. How Poetry Became a Healing Tool While bedridden, Jasmin returned to writing poetry — something she loved as a child — and discovered that creative expression became a powerful emotional detox and survival mechanism. Buy Bittersweet Body: a Poetic Memoir, Jasmin's debut poetry book, inspired her life’s mission: to illuminate the invisible in a visible world. The Importance of Detoxification and Nervous System Healing Jasmin discusses the therapies that helped her most, including: Sauna therapy Binders Meditation Faith and prayer Journaling Acupuncture Gentle movement Emotional release through writing Learning to Receive Help One of the most moving parts of the interview centers around Jasmin’s struggle with independence, vulnerability, and learning how to accept support from loved ones during her healing journey. Key Takeaways From Jasmin Perdomo’s Lyme Journey Healing from Lyme disease requires addressing the physical, emotional, and spiritual body. Detoxification can be just as important as antimicrobial treatment. Creativity and self-expression can become powerful healing tools. Nervous system regulation matters in chronic illness recovery. You are not weak for asking for help. Healing is possible — even after years of suffering. Quotes From This Episode “Poetry saved my life. It gave me mouth-to-mouth resuscitation when I couldn’t breathe.” “When my body became a stranger, writing helped me remember who I was.” “You are not weak for asking for help.” “Healing isn’t just physical. It’s emotional, spiritual, and deeply personal.” About Tick Boot Camp Tick Boot Camp is a Lyme disease advocacy platform dedicated to helping people liberate themselves and others from Lyme disease through education, validation, community, and hope. Through powerful conversations with patients, doctors, researchers, and healers, Tick Boot Camp reminds listeners that they are not alone — and that healing is possible. 🎧 Listen to more episodes

    1h 36m
  3. Jun 6

    Nicole O’Donnell on Resilient Hope, Chronic Lyme Disease & Healing Through Community

    In this powerful episode of the Tick Boot Camp Podcast, we sit down with Nicole O’Donnell—author of Resilient Hope: A Memoir of Life With Chronic Illness—to discuss her deeply personal Lyme disease journey, the emotional realities of chronic illness, and the transformative power of community, mindset, and hope. Nicole shares how her life changed after developing debilitating Lyme disease symptoms, the years of medical confusion that followed, and how COVID intensified her chronic illness experience. Through vulnerability and honesty, she opens up about navigating fear, identity loss, parenting while chronically ill, and ultimately discovering purpose through advocacy and storytelling. This conversation also explores the importance of patient-doctor relationships, nervous system regulation, healing mindset, and how Lyme disease impacts entire families—not just the patient. Most importantly, Nicole reminds listeners that healing is possible, and no one has to face Lyme disease alone. In This Episode, You’ll Learn: Nicole O’Donnell’s personal chronic Lyme disease journey How Lyme disease symptoms can become invisible and misunderstood The emotional impact of medical dismissal and misdiagnosis Why mindset and nervous system regulation matter in healing How chronic illness affects marriage, parenting, and family dynamics The role community plays in Lyme disease recovery Why Nicole wrote Resilient Hope How storytelling helps validate and empower Lyme patients The importance of hope, advocacy, and finding purpose through adversity About Nicole O’Donnell Nicole O’Donnell is a Staten Island-based entrepreneur, mother, advocate, and author of Resilient Hope: A Memoir of Life With Chronic Illness. Through her writing and advocacy, Nicole seeks to help people living with Lyme disease and chronic illness feel seen, heard, and supported. Her book weaves together stories from members of the Lyme disease community to create a message of resilience, healing, and connection. Read More About Nicole’s Manhattan Book Launch Tick Boot Camp recently attended Nicole O’Donnell’s inspiring Manhattan book launch event, where nearly 1,000 people gathered in support of the Lyme disease community and the message behind Resilient Hope. Explore More Tick Boot Camp Resources 🎙 Tick Boot Camp Podcast 👩‍⚕️ Lyme Doctor Interviews 🧠 Tick Bite Blueprint 🧪 Lyme Testing Resources 🔬 Learn Why Lyme Persists Final Thoughts Nicole O’Donnell’s story is a reminder that chronic Lyme disease affects every part of a person’s life—but it can also become a catalyst for transformation, deeper connection, and purpose. Through Resilient Hope, Nicole is helping build a stronger Lyme disease community rooted in validation, compassion, and healing. If you or someone you love is navigating Lyme disease, this episode offers encouragement, perspective, and a powerful reminder that resilient hope is possible.

    1h 4m
  4. Apr 25

    From Vision Loss to Voice: Marina Morgan’s Lyme Disease Journey

    In this powerful episode of the Tick Boot Camp Podcast, Matt Sabatello and Rich Johannesen sit down with Marina Morgan, a professional singer, songwriter, real estate agent, and Lyme disease survivor from New York and New Jersey. Marina shares the deeply personal story of how a vibrant, high-energy young woman who loved running, fitness, and music suddenly found her life turned upside down by Lyme disease in her early twenties. What began as stomach issues quickly progressed into neurological symptoms, extreme fatigue, balance problems, and ultimately sudden vision loss in one eye — a terrifying turning point that led to her eventual diagnosis. After seeing multiple doctors and facing potential misdiagnoses such as multiple sclerosis and scleroderma, Marina was finally diagnosed with Lyme disease through a Western Blot test by Dr. Pollack. Her treatment included 18 months of IV antibiotics through a PICC line, followed by another year of treatment after a later flare-up. Today, Marina continues to navigate chronic Lyme symptoms while building a career in music, real estate, and fitness, demonstrating resilience, perseverance, and determination even on difficult days. Her story is a powerful reminder that Lyme disease can affect anyone — even young, healthy, active people — and that persistence, positivity, and support are essential in the healing journey. About Marina Morgan Marina Morgan is a professional singer and songwriter who has appeared on the Today Show, was named Elvis Duran’s Artist of the Month, and has been featured on iHeartRadio and in multiple publications as an emerging artist. In addition to her music career, Marina works as a real estate agent serving New York and New Jersey and as a gym manager, continuing to stay connected to the world of fitness despite the physical challenges created by Lyme disease. Marina has also used her music to express the realities of chronic illness. Her song “Paralyzed” captures the emotional and physical struggle many Lyme patients face when their bodies no longer cooperate with the life they once lived. Watch Marina’s Lyme-inspired music video “Paralyzed" Follow Marina on Instagram Key Topics Discussed in This Episode Life Before Lyme Disease Before getting sick, Marina lived an extremely active lifestyle. She ran miles every day simply for enjoyment, maintained multiple jobs, and had a vibrant social life. Fitness and movement were central to her identity, and she describes having seemingly endless energy. Lyme disease dramatically altered that reality. Early Symptoms and Sudden Vision Loss Marina’s illness began subtly with stomach issues and fatigue, but symptoms soon escalated. She began experiencing: Severe fatigue Weakness in her legs Balance and coordination issues Neurological symptoms Brain fog Loss of vision in one eye The sudden vision loss was the turning point that signaled something much more serious was happening. Misdiagnosis and the Search for Answers Before receiving a Lyme diagnosis, doctors suspected conditions such as multiple sclerosis (MS) and scleroderma. Marina visited several doctors and specialists before finally receiving the correct diagnosis. Her father, who had previously experienced Lyme disease himself, recognized the possibility and helped advocate for Lyme testing. She was ultimately diagnosed at age 23 through a Western Blot blood test by Dr. Pollack. Intensive Lyme Treatment Following her diagnosis, Marina underwent 18 months of intravenous antibiotic treatment through a PICC line, one of the more aggressive approaches used for severe Lyme disease. Years later, after experiencing a flare-up, she required another year of treatment. Today she is not undergoing active Lyme treatment but continues supportive wellness practices including: Infrared sauna Yoga Probiotics Living with Chronic Lyme Marina estimates she has recovered to about 60% of her pre-Lyme health. The most persistent symptom she continues to battle is extreme fatigue, which can make even simple daily activities exhausting. She describes the unpredictability of chronic Lyme — how a good day can be followed by days or weeks of exhaustion. Despite these challenges, Marina continues to work, maintain relationships, and pursue her passions. Music as a Voice for Lyme Patients Marina has channeled her experience with chronic illness into her music. Her song “Paralyzed” captures the emotional reality of Lyme disease — the feeling of being trapped in a body that no longer functions the way it once did. The song resonates deeply with Lyme patients and others living with invisible illness. Watch the video here Advice for People Fighting Lyme Disease Marina encourages patients not to give up during the darkest moments of illness. Lyme disease can be physically and emotionally overwhelming, but maintaining hope and continuing to pursue healing strategies can make a meaningful difference. She stresses the importance of: Listening to your body Giving yourself grace Staying mentally resilient Continuing to search for solutions Key Takeaways Lyme disease can affect young, healthy, highly active people Neurological symptoms like vision loss can occur with Lyme disease Misdiagnosis is common in complex Lyme cases Long-term IV antibiotic treatment is sometimes required Chronic symptoms can persist even after treatment Mental resilience plays a major role in managing chronic illness

    1h 14m
  5. Apr 18

    At the Frontlines of Chronic Illness: ILADS Expert Panel Webinar

    This special Tick Boot Camp Podcast crossover features the full International Lyme and Associated Diseases Society (ILADS) webinar recording, “At the Frontlines of Chronic Illness: Conversations with ILADS Experts.” In this dynamic panel discussion, leading clinicians and specialists unpack why Lyme disease and other infection-associated chronic illnesses are so misunderstood, why testing fails so many patients, and what it really takes to heal—brain, immune system, mitochondria, and terrain included. Moderated by Rich Johannesen (Tick Boot Camp), the panel delivers practical insights and hopeful, patient-centered guidance for anyone navigating complex chronic illness—whether you’re a patient, caregiver, clinician, or advocate. Featured Panelists Chris Winfrey, MD — Psychiatrist; Medical Director, New Image Wellness Nicole Bell — “The Lyme Disease Engineer”; CEO, Galaxy Diagnostics Tania Dempsey, MD — Medical Director, AIM Center for Personalized Medicine Melanie Stein, ND — Naturopathic Doctor; Author focused on cellular wellness and healing terrain Host/Moderator: Rich Johannesen (Tick Boot Camp) ILADS Intro: Ali Moresco (ILADS) Episode Highlights ILADS Mission and Why This Webinar Matters The webinar opens with ILADS’ mission: improving diagnosis and treatment of Lyme disease and associated illnesses through research, education, and policy. ILADS emphasizes physician training and patient-centered care, while also supporting the educational mission of ILADEF. Rich frames the night as a rare opportunity to hear from experts working at the front lines of complex chronic illness—especially for patients who’ve been dismissed, misdiagnosed, or told their symptoms “don’t make sense.” Segment 1: Brain Health, Neuroimmune Illness, and Why Lyme “Feels Like Dementia” Chris Winfrey, MD Dr. Winfrey introduces a core theme: Lyme is not only an infection—it often behaves like a neuroimmune illness. Key takeaways: The brain is a high-energy, high-immune-demand organ, uniquely vulnerable to infection-driven inflammation and toxicity. Lyme can disrupt brain function through: Blood flow issues Synaptic dysfunction Myelin damage Network-level disruption, not just “neurotransmitters” He describes brain function through networks that Lyme can destabilize: Default Mode Network (internal reflection) Salience Network (switching between networks) Central Executive Network (planning/organization) Action Network (execution) Autonomic Network (regulation) Limbic Network (threat/fear response) The result: patients often describe “brain shutdown,” confusion, cognitive impairment, and even dementia-like symptoms. A major reframing: Emotions are not “non-physical.” They are measurable physiological states. Lyme-driven nervous system injury can create emotional disturbance because the biology is disturbed. Segment 2: Poly-microbial Infection, Fight-or-Flight, and the Belief-Healing Loop Winfrey + Rich Discussion Rich frames humans as spiritual, emotional, and physical beings, and asks how chronic infection impacts both body and emotional resilience. Key points: Lyme can cross the blood-brain barrier and affect virtually any organ system. The nervous system becomes a “central battleground,” and measurement is hard because nervous system dysfunction isn’t captured well by simple bloodwork. Rich and Dr. Winfrey explore how illness disrupts perception, decision-making, and our ability to interpret the world—especially when gut function and intuition feel “offline.” The healing paradox: Chronic stress and “fighting your way to healing” can backfire. Dr. Winfrey emphasizes that healing requires a parasympathetic state—rest, digest, repair—and that this often involves acceptance, surrender, trust, and safety. Segment 3: The State of Testing—Why So Many Patients Test Negative Nicole Bell (Galaxy Diagnostics) Nicole shares her personal motivation and professional mission: testing determines treatment, reimbursement, and belief—and too many patients are failed by existing tools. Indirect testing (antibody testing): The standard approach relies on antibodies—meaning it depends on the immune system behaving predictably. But Lyme and other stealth pathogens evade and suppress immune responses. Even in controlled research models, two infected subjects can show completely different antibody patterns. Immunosuppression (illness severity, medications like steroids, immune dysregulation) can reduce antibody reliability. Direct testing (pathogen detection):Nicole contrasts Lyme testing with illnesses like COVID—where you use tests that look for the pathogen itself (PCR/antigen), not just antibodies. Why direct detection is hard in Lyme: Pathogens can be low abundance They can be tissue-sequestered Sampling matters Why urine can matter for Lyme: Lyme may not stay in blood, but it can shed proteins/antigens that filter into urine. Galaxy’s approach includes methods to capture, concentrate, and detect those markers. New diagnostics focus: Genus-level screening for the “3Bs” (Borrelia, Bartonella, Babesia) Reducing guessing when symptoms overlap and co-infections “masquerade” as each other Segment 4: Immune Dysfunction, Mast Cells, and Why Antibody Testing Can Go Haywire Tania Dempsey, MD (AIM Center for Personalized Medicine) Dr. Dempsey explains the immune system through two major branches: Innate immune system (fast, primitive defense) Adaptive immune system (antibodies, longer-term response) Mast cells as first responders: Mast cells detect “danger” and release inflammatory mediators (histamine and many others). In chronic infection, mast cells can remain persistently activated, releasing hundreds of inflammatory compounds. Why antibody tests fail (two patterns): Immune suppression → insufficient antibody production → false negatives Immune chaos → excessive, inappropriate antibody production → confusing positives - Positive Lyme bands “everywhere” - Positive autoantibodies without classic autoimmune disease patterns - “Everything looks positive” because signaling is dysfunctional Her central philosophy:It’s not only about killing the bug. It’s about fixing immune regulation so the body can actually clear or control infection. She also names the broader context: modern toxic load (mold, plastics, pesticides, “forever chemicals”) primes the immune system into dysregulation before infections even arrive. Segment 5: Advanced Immune-Modulating Tools Therapeutic Plasma Exchange + SOT Dr. Dempsey discusses therapies she’s excited about, especially for complex, stuck cases: Therapeutic Plasma Exchange (TPE / plasmapheresis): Removes plasma (where antibodies, inflammatory mediators, and “garbage” accumulate) Replaces with albumin (and sometimes IVIG) Concept: reduce inflammatory burden + toxic load to reset the terrain SOT (Supportive Oligonucleotide Technique): Molecular targeted approach designed to reduce replication of specific pathogens More targeted than “wide-net” antimicrobial approaches Used strategically after lowering inflammatory/toxic burden She emphasizes: not for everyone, not a universal cure—but promising enough to merit formal publication. Segment 6: GLP-1 Agonists and Mast Cell Stabilization “Brain-melt” moment, revisited Dr. Dempsey explains why drugs commonly known for diabetes/weight loss may have immune benefits: Mast cells have receptors for GLP and GIP hormones Patients showed improvements beyond weight: cognitive function, inflammation, immune stability She describes: Semaglutide (Ozempic/Wegovy) Tirzepatide (Mounjaro/Zepbound) Emerging triple agonists (GLP-1/GIP/glucagon pathways) Her clinical approach has moved these agents earlier in care plans for immune stabilization in select cases. Segment 7: Cellular Healing, Mitochondria, and the Terrain Melanie Stein, ND Dr. Stein brings it home: healing often stalls when we focus only on killing pathogens, but don’t repair the cellular damage. Core concepts: Lyme damages cell membranes, disrupting what goes in/out and how cells communicate. It contributes to mitochondrial dysfunction, reducing ATP (energy currency). If cells stay in “alarm mode,” healing remains blocked. Cell membrane therapy and terrain support: IV and oral lipid support (phospholipids, phosphatidylcholine, omega fatty acids) Personalized support based on lipidomic patterns Supportive therapies to reduce oxidative stress and “toxic fats” Focus on signaling safety to the body—so repair can resume Cell Danger Response:A key theme: even after infections reduce, the body may remain stuck in a persistent defense state, requiring cellular and nervous system support to exit “danger mode.” Regulation Before Eradication Panel Reflection Round As the panel closes, several themes converge: Limbic system + autonomic nervous system regulation is foundational “Regulation becomes before eradication” Healing requires safety, predictability, and nervous system calm Chronic illness can block our ability to connect—especially in relationships—because survival physiology dominates Dr. Dempsey adds that limbic retraining / nervous system reset is often the first step she starts with in her practice. Question and Answer Highlights Lyme and Cancer? The panel notes emerging signals connecting tick-borne illness and certain cancers, but emphasizes that more research is needed to determine causality. Herniated discs, connective tissue, and chronic infection The discussion highlights potential links through: connective tissue disruption collagen damage mast cell mediators (enzymes that affect tissue integrity) infection-driven inflammation Cross-reactive antibody results (example: Brucella) The group explains how antibody testing can produce confusing results due to immune dysregulation and cross-reactivit

    1h 27m
  6. Apr 11

    Pediatric Lyme, Autism Regression, PANS/PANDAS & Root-Cause Healing | Dr. Somer DelSignore

    In this powerful in-person interview at the Tick Boot Camp studio, Matt Sabatello sits down with Dr. Somer DelSignore, DNP, a board-certified pediatric practitioner specializing in Lyme disease, tick-borne co-infections, PANS/PANDAS, autoimmune and neuroimmune disorders, autism-like regression, and congenital tick-borne illness. This episode is essential listening for parents who have been told to “wait and see,” families who have seen multiple specialists without answers, and anyone trying to understand how infection, inflammation, immune dysfunction, and nervous system imbalance can impact a child’s brain and development. 🎙 About Dr. Somer DelSignore Dr. DelSignore began her career in traditional pediatric medicine before recognizing that many children with complex chronic illness could not be properly treated in 10–15 minute appointments. Her clinical evolution accelerated after: Training with Dr. Richard Horowitz (tick-borne disease complexity and layered treatment strategies) Training with Dr. Kenneth Bock (autism and autoimmune encephalopathy patterns) Identifying the infectious and immune triggers driving neuropsychiatric symptoms Today, she runs a private practice in upstate New York where she treats children (and a small cohort of adults) using a comprehensive, root-cause framework. 🧠 Autism, Lyme & Autoimmunity — Connecting the Dots Dr. DelSignore explains that autism is often a cluster of symptoms, not a single-gene condition. In her clinical experience, many children experience immune-triggered neuroinflammation that presents as: OCD Anxiety Rage Intrusive thoughts Impulsivity Hallucinations Developmental regression Lyme and co-infections such as Bartonella and Babesia can activate autoimmune responses that interfere with neurotransmitter signaling. When inflammation blocks receptors for dopamine and serotonin, psychiatric symptoms emerge. Her message is clear:These symptoms are often biomedical — not simply behavioral. 🦠 Why “Root Cause” Is Rarely One Thing Healing rarely comes down to one pathogen. Children may present with overlapping contributors such as: Lyme disease and co-infections Mold and mycotoxins Heavy metals Epigenetic pathway dysfunction Detox impairment Nervous system dysregulation Dr. DelSignore emphasizes layered pattern recognition and systematic evaluation rather than single-diagnosis thinking. 🧬 Treatment Approach: Layered, Sequenced & Individualized There is no cookie-cutter protocol. Her framework may include: Targeted antibiotic combinations Herbal antimicrobials Biofilm and fibrin support Gut protection from day one Detox support (liver, kidney, lymphatic) Ozone therapy SOT (gene-silencing therapy) IVIG for autoimmune modulation (when appropriate) Plasmapheresis referral Regenerative PRP strategies Sequencing matters. Some children require detox and nervous system stabilization before antimicrobial treatment begins. 🧱 Biofilms & Tissue Infection Dr. DelSignore confirms: Biofilms are real and clinically significant Microbes communicate and protect one another Chronic infections often reside in tissue, not just blood Killing pathogens without detox support can worsen flares Her philosophy:Eliminate pathogens while simultaneously rebuilding the body. 🌿 Detox, Regeneration & the Nervous System Pathogen elimination is only part of recovery. Healing also requires: Supporting liver and kidney detox pathways Encouraging lymphatic flow Gentle sauna when tolerated Epsom salt baths Breathwork and box breathing Vagus nerve stimulation Nervous system retraining Many children are stuck in chronic sympathetic (“fight-or-flight”) mode. True recovery requires shifting into parasympathetic “rest and repair.” ❤️ A Story of Hope Dr. DelSignore shares the case of a child born with congenital tick-borne infections who: Was non-verbal Required feeding tube support Was diagnosed with autism After comprehensive treatment and immune regulation, the child: Became verbal Engaged socially Reached developmental milestones Thrives in school It’s a reminder that recovery is possible—even in severe presentations. 🏥 The Care Coordination Challenge Families often see 10–15 specialists before reaching her office. Dr. DelSignore stresses the importance of: A “medical home” One lead clinician acting as quarterback Coordinated communication among providers She also discusses the urgent need for legislative and insurance reform to support time-intensive chronic illness care. 🌎 Looking Forward Dr. DelSignore hopes for: Increased research funding Broader recognition of infection-driven neuroinflammation Earlier pediatric intervention A shift toward prevention and health-promotion medicine Her belief: When properly supported, the body can heal. 🔑 Key Takeaways Trust parental intuition Neuropsychiatric symptoms may be immune-driven Detox and gut health are foundational Nervous system regulation is critical Healing is possible—even in complex cases

    1 hr
  7. Apr 4

    Healing Chronic Lyme Through Terrain, Stress Physiology & Liquid Intelligence | Frédéric Roscop

    Frédéric Roscop, French-born osteopath and founder of AEQUIL, joins the Tick Boot Camp Podcast as our first-ever in-studio international guest, flying in from London to Long Island to share his personal battle with chronic Lyme disease—and the breakthrough that reshaped his life and career. After decades of unexplained symptoms, misdiagnoses, heart inflammation, neurological dysfunction, and failed treatment attempts across multiple countries, Frédéric discovered that killing microbes alone wasn’t enough. His recovery began when he shifted focus from chasing pathogens to restoring the body’s foundational terrain—supporting immune regulation, detoxification, cellular function, stress physiology, and energetic balance. In this deeply reflective and technical conversation, Frédéric shares how childhood tick exposure in rural France, years of undiagnosed Borrelia and Bartonella infection, and repeated medical dead-ends ultimately led him to develop a patented biotech system designed to help others reset their foundational wellbeing. What You’ll Learn in This Episode Growing Up in Tick Territory Frédéric describes growing up in rural France, frequently covered in ticks as a child—long before Lyme disease was widely recognized in Europe. Early symptoms included: Chronic insomnia and hyperactivity Digestive dysfunction and blood sugar instability Visual disturbances and light sensitivity Emotional instability and neurological symptoms Recurrent inflammation At 16, following general anesthesia for a broken nose, he experienced what he now recognizes as a major Lyme “crash,” leading to cognitive decline, emotional dysregulation, and worsening physical inflammation. Heart Inflammation & Athletic Collapse By age 17–18, Frédéric’s promising volleyball career ended due to inflammatory joint disease and recurring pericarditis (heart inflammation)—which would return six times over the next 15 years. Antibiotics temporarily improved symptoms, but the root cause remained unidentified. “I Didn’t Even Know What Lyme Disease Was” As a young osteopath in practice, Frédéric recalls a patient asking whether her symptoms could be Lyme disease. At the time, he had never been trained on it. Years later, another patient was hospitalized with Lyme-related encephalitis—triggering Frédéric’s realization that Lyme might explain both his patients’ suffering and his own. This episode includes an honest discussion about: Medical training gaps Diagnostic limitations The importance of humility in healthcare Why the doctor–patient relationship must be a partnership Diagnosis: Borrelia, Bartonella & More Specialty testing eventually revealed: Borrelia Bartonella Viral findings including Epstein-Barr Virus (EBV) Heavy metal burden (notably elevated mercury) Frédéric began aggressive antibiotic and detox protocols—but experienced severe gut collapse and worsening terrain. Despite trying treatments across Europe, the U.S., China, India, and Switzerland—including antimicrobial, herbal, and integrative approaches—he improved only marginally. The Turning Point: It’s Not Just the Bug — It’s the Terrain Frédéric revisited the foundational debate in medicine: Louis Pasteur: It’s the germ. Claude Bernard: It’s the terrain. His breakthrough came when he shifted focus to rebuilding: Gut function Cellular membranes Detox pathways Nervous system regulation Emotional and energetic resilience Rather than focusing exclusively on killing microbes, he asked: Does the body have the capacity to self-regulate and self-repair? From that question, AEQUIL was born. What Is AEQUIL? AEQUIL is a biotech wellness system built around a patented technology Frédéric calls Liquid Intelligence — a formulation combining: Structured/dynamised water Botanicals Vitamins and electrolytes Biochemical and biophysical support The system supports: Brain, heart, gut, liver, and immune foundations Detoxification and lymphatic flow Stress physiology Emotional and energetic regulation The AEQUIL Deep Reset System Maintain (Foundational Support) A daily liquid formula designed to nourish the body’s core systems and support cellular regulation. Suggested use: ½ teaspoon morning ½ teaspoon evening Reset (Deep Reset Protocol) A structured approach to support: Microorganisms (bacteria, viruses, fungi, parasites) Micro-toxins (detox pathways) Micro-traumas (stress and emotional stagnation) The protocol is phased to reduce Herx reactions and build resilience gradually, with many users reporting a noticeable physiological shift around weeks 8–10. Everyday Support Wearable patches and digital wellness tools (affirmations, breathwork) designed to support mood, sleep, energy, and immune balance during recovery. Core Message of This Episode Chronic Lyme recovery is rarely about one silver bullet. It requires: Restoring foundational systems Supporting detox and immune function Addressing nervous system and stress patterns Recognizing both biochemical and energetic influences Frédéric’s story is one of humility, evolution, and transformation—from a practitioner unaware of Lyme disease to a global wellness innovator working to support both patients and healthcare providers. 🎧 Tick Boot Camp Listener Exclusive AEQUIL is offering Tick Boot Camp listeners: 30% off with code: TB30 Listeners can email: info@aequil.com Emails will connect you directly with Frédéric for guidance on: The Deep Reset protocol What to expect Choosing the right welcome pack

    1h 41m
  8. Mar 28

    MCAS, Chronic Lyme Disease, GLP-1 Agonists, Biofilms, and the Future of Precision Medicine — Dr. Tania Dempsey, MD

    GLP-1 Agonists, MCAS, Lyme Disease, and the Future of Precision Medicine In this powerful Tick Boot Camp Podcast interview, Matt Sabatello sits down with Dr. Tania Dempsey, MD, a board-certified internal medicine physician and internationally recognized expert in Mast Cell Activation Syndrome (MCAS), Lyme disease, autoimmune conditions, and complex chronic illness. In this comprehensive conversation, Dr. Dempsey delivers one of the most forward-thinking and in-depth discussions ever featured on the podcast — connecting the dots between persistent symptoms after Lyme, immune dysregulation, biofilms, nervous system dysfunction, and groundbreaking research on GLP-1 receptor agonists as mast-cell stabilizers. This episode offers science, clinical insight, and — most importantly — hope for patients who have tried everything and are still struggling. Lyme Disease, MCAS, and Why Patients Stay Sick Why Treating Lyme Alone Is Often Not Enough Dr. Dempsey explains why many patients continue to experience inflammation, pain, neurological symptoms, and relapses even after treating Lyme disease and co-infections. According to her clinical experience, this is most often due to primary Mast Cell Activation Syndrome, not persistent infection alone. Key insight: > Lyme disease frequently acts as the trigger, but MCAS is often the driver of ongoing symptoms. Dr. Dempsey clarifies the critical difference between: Primary MCAS (pre-existing immune dysfunction worsened by infections) Secondary MCAS (rare; resolves completely once infection is treated) She notes that in decades of clinical practice, she has never seen true secondary MCAS fully resolve without ongoing mast-cell management. SOT Therapy: When, Why, and How It Works Best Dr. Dempsey provides a nuanced and experience-based explanation of Supportive Oligonucleotide Technique (SOT) for Lyme and co-infections. She addresses common criticism: One-time SOT treatments are rarely sufficient Chronic Lyme often involves multiple strains of Borrelia , Babesia , and Bartonella Her most successful cases involve: Repeated testing Sequential SOT treatments targeting specific strains Immune system support between rounds Adjunctive therapies such as herbs, antiparasitics, and mast-cell stabilization She shares a remarkable case of a young woman with severe neuropsychiatric symptoms who — after years of persistent SOT treatment combined with MCAS management — is now thriving, off psychiatric medications, and successfully completing college. Biofilms: Why They Matter in Chronic Infection Dr. Dempsey firmly states that biofilms are a critical barrier to recovery in chronically ill patients. Key points: Biofilms exist in the gut, sinuses, blood, and tissues They protect microbes from antibiotics, herbs, and immune attack Resistant biofilms may involve extracellular DNA (Z-DNA), discussed at ILADS Therapies discussed: Enzymes such as lumbrokinase and nattokinase Ozone therapy Therapeutic Plasma Exchange (TPE) for severe cases Her message is clear: if you cannot reach microbial reservoirs hidden in biofilms, infections cannot be fully controlled. GLP-1 Agonists, Immune Modulation, and Breakthrough MCAS Research GLP-1 Receptor Agonists as Mast-Cell Stabilizers Dr. Dempsey presents groundbreaking findings from her published case series: “The Utility of GLP-1 Receptor Agonists in Mast Cell Activation Syndrome” Key details: 47-patient case series Micro-dosing of GLP-1 agonists Primary medications used: tirzepatide (Mounjaro / Zepbound) and semaglutide (Ozempic / Wegovy) Unlike weight-loss protocols, Dr. Dempsey uses very low doses to target immune modulation — not appetite suppression. What GLP-1 Therapy Improved in MCAS & Lyme Patients Reported improvements included: Cognitive clarity and brain fog Chronic pain Neuropsychiatric symptoms Anxiety and depression Gastrointestinal symptoms Systemic inflammation Hormonal dysregulation In some cases, patients experienced improvement within one or two doses. Dr. Dempsey explains that mast cells express GLP-1 receptors, and activation sends a signal of safety, reducing inflammatory mediator release. Unexpected Findings: Muscle Mass and Antibody Reduction Contrary to common concerns, Dr. Dempsey observed: Preserved or increased muscle mass in the majority of patients Improved mitochondrial function and exercise tolerance Reduction in chronic antibody production (including Lyme Western Blot bands) She shares a striking case where a patient with long-standing positive Lyme antibodies saw antibody levels decline for the first time in over a decade after GLP-1 therapy — despite infection already being treated. This supports her hypothesis: > MCAS can drive persistent immune activation even when infection is no longer present. Side Effects, Screening & Who Should Not Use GLP-1s Potential side effects (usually mild): Nausea Delayed gastric emptying Occasional vomiting in sensitive patients Important clinical notes: Some patients respond better to semaglutide vs tirzepatide A small subset may require dose cycling or pulsing Antibody formation against GLP-1 drugs is a potential research focus Non-Pharmaceutical Alternatives to Increase GLP-1 Activity For patients who cannot tolerate medications, Dr. Dempsey outlines alternatives. Herbal & Supplement Options OptimumGLP Synergy (herbal blend designed to support GLP-1 signaling) Calocurb (GLP-1 supportive compound) These options may: Reduce inflammation Help stabilize appetite and blood sugar Calm mast-cell activity Diet-Based Strategies Dr. Dempsey explains why higher-protein and carnivore-leaning diets may benefit MCAS and Lyme patients: Protein and fat stimulate endogenous GLP-1 Reduced food triggers Improved metabolic stability Patients do not need to eat exclusively meat — but increasing high-quality protein intake is often beneficial. Nervous System, Trauma & Mast Cell Feedback Loops The episode explores how: Mast cells and nerves exist in a bidirectional feedback loop Chronic fight-or-flight worsens immune activation Therapies discussed: Limbic retraining programs ( Primal Trust , Gupta Program) Vagal nerve stimulation Apollo Neuro wearable Ketamine-assisted therapy Psychedelic microdosing (emerging area) Breaking the mast-cell / nervous-system loop is often essential for healing. Women’s Health, PCOS & Autoimmune Illness Dr. Dempsey shares a critical insight: > In her practice, every PCOS patient also has MCAS. She explains how: Mast cells respond to estrogen, progesterone, insulin, and cortisol Hormonal fluctuations can trigger MCAS flares MCAS may underlie PMS, PMDD, endometriosis, and reproductive pain syndromes GLP-1 therapy may offer new hope for women suffering from inflammatory gynecologic symptoms linked to Lyme and MCAS. Advocacy, ILADS & The Future of MCAS Research Dr. Dempsey discusses her work with: ILADS (International Lyme and Associated Diseases Society) ISMCAS (International Society for Mast Cell Activation Syndrome) ISMCAS goals include: Funding MCAS research Educating clinicians globally Supporting patients and advocacy efforts She encourages patients to: Educate themselves Share credible research with providers Move on from doctors unwilling to listen Final Takeaway This episode redefines what root-cause medicine truly means. Healing chronic Lyme disease often requires addressing: Immune dysregulation Mast cell activation Nervous system dysfunction Hormonal imbalance Metabolic inflammation Dr. Tania Dempsey offers a roadmap — grounded in science, compassion, and innovation — for patients

    2h 1m
5
out of 5
75 Ratings

About

The goal of the Tick Boot Camp Podcast is to help people liberate themselves and others from suffering caused by Lyme disease through validation, community building, belief that healing is possible, and modeling success. Listen to our Tick Boot Camp podcast using all major podcast streaming services such as Apple Podcasts, Spotify, and YouTube Music. Our podcast is also integrated with smart home devices, such as Amazon Alexa and Apple TV. Ask your device to "play the Tick Boot Camp Podcast!"

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