Vaccine reactogenicity

This review article thoroughly examines vaccine reactogenicity, which encompasses the common, often mild, inflammatory responses individuals experience post vaccination, such as soreness or fever. The authors explore the underlying biological mechanisms that cause these reactions, detailing how the body's immune system responds to vaccine components. Furthermore, the paper investigates various factors that can influence reactogenicity, including host characteristics, vaccine composition, and administration techniques. Ultimately, the article aims to enhance understanding among healthcare professionals and the public to maintain confidence in vaccination programmes by managing expectations and mitigating anxiety related to side effects.

Review paper:

Hervé, C., Laupèze, B., Del Giudice, G. et al. The how’s and what’s of vaccine reactogenicity. npj Vaccines 4, 39 (2019).

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