Despite being the most studied supplement of all time, creatine is making a big resurgence. That's why we decided to rebroadcast this highly informative episode, that is more relevant now, than when it was originally posted. It’s been the hot topic in the health podcast space, as new scientific evidence is showing creatine is about more than looking big, but has big and important effects on brain health and overall longevity. But, like all things, creatine needs to be handled with care. It needs to be the right type, at the right dose, at the right times, with the right movement and for the right person. That’s why it was fundamentally important for me to get a true creatine expert on the show, Dr Darren Candow. Dr. Darren Candow is a professor specializing in exercise physiology, nutrition, and aging. He supervises the Aging Muscle and Bone Health Laboratory, where the primary research focus is to develop effective lifestyle interventions involving nutrition—primarily creatine monohydrate—and physical activity, particularly resistance training. These interventions aim to improve muscle, bone, and brain health and function, with both practical and clinical relevance. To date, Dr. Candow has published over 120 peer-reviewed journal articles, supervised more than 20 MSc/PhD students, and secured research funding from the Canadian Institutes of Health Research, Canada Foundation for Innovation, the Saskatchewan Health Research Foundation, the National Institutes of Health, and the Nutricia Research Foundation. Join us as we explore: Everything about creatine! What it is, is it right for you, the safest form, dosage, its most important (and surprising) effects, why it’s the most studied supplement ever and some risks and side effects.Creatine’s incredible effects on a sleep deprived and exhausted brain!Creatine’s relationship to caffeine, hyperbaric chambers/hypoxia and TRT.Dr Candow’s recommended morning exercise and creatine protocol.Does creatine cause you to gain weight, retain water, and is the loading phase a real thing?Veganism and creatine.Mention: Study - Creatine and anti-depressants, Roitman, S., Green, T., Osher, Y., Karni, N., Levine, J., & Levine, S. (2012). Creatine monohydrate in resistant depression: A randomized, double-blind, placebo-controlled trial. American Journal of Psychiatry, 169(7), 779-784. https://doi.org/10.1176/appi.ajp.2012.11091452 Study - Creatine and pregnancy, Ellery, S. J., LaRosa, D. A., Kett, M. M., Della Gatta, P. A., Snow, R. J., Walker, D. W., & Dickinson, H. (2016). Dietary creatine supplementation during pregnancy: A study on the effects of creatine supplementation on creatine homeostasis and renal excretory function in spiny mice. Amino Acids, 48(8), 1819–1830. https://doi.org/10.1007/s00726-015-2150-7 Study - Creatine and sleep deprivation, Gordji-Nejad, A., Matusch, A., Kleedörfer, S., Patel, H. J., Drzezga, A., Elmenhorst, D., Binkofski, F., & Bauer, A. (2024). Single dose creatine improves cognitive performance and induces changes in cerebral high energy phosphates during sleep deprivation. Scientific Reports, 14, 4937. https://doi.org/10.1038/s41598-024-54249-9 Person - Stuart Phillips, https://experts.mcmaster.ca/display/phillis Support the show Follow Steve's socials: Instagram | LinkedIn | YouTube | Facebook | Twitter | TikTok Support the show on Patreon: As much as we love doing it, there are costs involved and any contribution will allow us to keep going and keep finding the best guests in the world to share their health expertise with you. I’d be grateful and feel so blessed by your support: https://www.patreon.com/MadeToThriveShow Send me a WhatsApp to +27 64 871 0308. Disclaimer: Please see the link for our disclaimer policy for all of our content: https://madetothrive.co.za/terms-and-conditions-and-privacy-policy/
