Regenerative Health with Max Gulhane, MD

Dr Max Gulhane

I speak with world leaders on circadian & quantum biology, metabolic medicine & regenerative farming in search of the most effective ways of optimising health and reversing chronic disease.

  1. 4d ago

    109. LDL & Better Metabolic Health: The Keto Cholesterol 'Paradox' | Dave Feldman

    Your waist shrinks. Your insulin falls. You feel better. But your LDL cholesterol goes up.  Dave Feldman joins me to unpack one of the most debated questions in low-carbohydrate nutrition: what does a substantial rise in LDL mean when other markers of metabolic health improve? Dave is an engineer, citizen scientist and lipid researcher who originated the term “lean mass hyperresponder”. He explains his lipid energy model and why some people eating very low-carbohydrate diets develop high LDL alongside high HDL and low triglycerides. We also examine his interpretation of the Keto-CTA research, the limitations of coronary plaque measurements, and the unanswered questions that require longer follow-up. Our conversation goes beyond blood markers to explore vascular injury and repair, immune responses, sleep and circadian biology. CONSULT DR MAX 🩺 Comprehensive Health Consulting & second opinion - www.drmaxgulhane.com/consulting PODCAST SPONSORS 🧡 HARDBLOCK Australia's Longest Running Bitcoin-only (₿) Exchange Use code REGENPOD for AUD 10 of bitcoin post verification  https://www.hardblock.com.au/join/REGENPOD SUPPORT MY WORK 🎤 PRIVATE MEMBERS GROUP on Skool platform - weekly Q&A, my 52-page eBook, PDF resource downloads & more. USD20/month, cancel anytime.  https://www.skool.com/dr-maxs-circadian-reset 🚨 DAYLIGHT COMPUTER. Blue-light free computer that doesn't wreck your circadian rhythm. Now shipping around the world. Code DRMAX for $25 off.   https://buy.daylightcomputer.com/DRMAX 🚨 VIVA RAYS. Premium blue light blocking glasses with the most useful 3 in 1 clip on frame sets. Code DRMAX for 15% off. https://vivarays.com/dr-maxgulhane 🚨 GEMBA RED. Highest quality photobiomodulation / redlight therapy devices, shipping within the USA. Code DRMAX for 10% off. https://gembared.com TIMESTAMPS 00:00 Introduction to Dave Feldman and his work 02:11 Case study of a low-carb diet and lipid changes 03:10 Understanding the lipid profile improvements 04:18 The impact of high LDL in metabolic health 05:25 The role of lipoproteins in fat transport 09:47 HDL as a marker of lipid turnover 11:41 The lean mass hyperresponder phenotype 17:03 Critique of the traditional lipid hypothesis 23:29 High LDL and cardiovascular disease risk 34:29 The immune response and vascular repair 42:47 Endothelial damage, repair, and circadian rhythm 52:38 Study findings on plaque progression and regression 01:02:09 Summary and future directions in lipid research Follow DAVE Website: https://cholesterolcode.com/ Follow DR MAX Website: https://drmaxgulhane.com/ Private Group: https://www.skool.com/dr-maxs-circadian-reset Courses: https://drmaxgulhane.com/collections/courses X: https://twitter.com/MaxGulhaneMD Instagram: https://www.instagram.com/dr_max_gulhane/ Apple Podcasts:  https://podcasts.apple.com/podcast/id1661751206 Spotify:  https://open.spotify.com/show/6edRmG3IFafTYnwQiJjhwR Linktree: https://linktr.ee/maxgulhanemd DISCLAIMER: The content in this podcast is purely for informational purposes and is not a substitute for professional medical advice, diagnosis, or treatment. Do not disregard professional medical advice or delay in seeking it because of something you have heard on this podcast or YouTube channel. Do not make medication changes without first consulting your treating clinician. #DaveFeldman #DrMaxGulhane #RegenerativeHealthPodcast #LeanMassHyperResponder #LMHR #LipidEnergyModel #KetoCholesterol #HighLDLOnKeto #LDLCholesterol #ApoB #Triglycerides #HDLCholesterol #MetabolicHealth #InsulinResistance #KetoCTA #CoronaryPlaque #Atherosclerosis #KetogenicDiet #CardiovascularHealth #CircadianRhythm Send us Fan Mail 🧡 HARDBLOCK Australia's Longest Running Bitcoin-only (₿) Exchange Use code REGENPOD for AUD 10 of bitcoin post account verification Support the show

  2. Sep 23

    108. Magnetism, Mitochondria & Human Health | Prof Geoffrey Guy & Alistair Nunn

    What happens to biology when Earth’s magnetic field becomes weaker—or disappears entirely? Dr Max Gulhane is joined by Professor Geoffrey Guy and Alistair Nunn of the Guy Foundation for a deep exploration of magnetobiology, geomagnetism, quantum biology and mitochondrial health. We discuss how magnetic fields influence mitochondrial membrane potential, electron transport, reactive oxygen species and cellular adaptation. We also  discuss the radical-pair mechanism, electron spin, animal magnetoreception, the South Atlantic Anomaly, geomagnetic storms and the non-linear biological effects of different magnetic-field strengths. CONSULT DR MAX 🩺 Comprehensive Health Consulting & second opinion - www.drmaxgulhane.com/consulting SUPPORT MY WORK 🎤 PRIVATE MEMBERS GROUP on Skool platform - weekly Q&A, my 52-page eBook, PDF resource downloads & more. USD20/month, cancel anytime.  https://www.skool.com/dr-maxs-circadian-reset 🚨 DAYLIGHT COMPUTER. Blue-light free computer that doesn't wreck your circadian rhythm. Now shipping around the world. Code DRMAX for $25 off.   https://buy.daylightcomputer.com/DRMAX 🚨 VIVA RAYS. Premium blue light blocking glasses with the most useful 3 in 1 clip on frame sets. Code DRMAX for 15% off. https://vivarays.com/dr-maxgulhane 🚨 GEMBA RED. Highest quality photobiomodulation / redlight therapy devices, shipping within the USA. Code DRMAX for 10% off. https://gembared.com TIMESTAMPS 00:51 The history of magnetobiology and animal navigation 01:52 Why space travel raises questions about magnetic fields 08:36 Oxidative stress and mitochondrial dysfunction 09:36 How weak can Earth’s magnetic field become? 11:16 Could geomagnetic variation act as a circadian signal? 15:54 Magnetic fields and mitochondrial membrane potential 19:09 The South Atlantic Anomaly and human health 23:07 Volcanoes, geology and local magnetic environments 29:20 Pole reversal and possible biological thresholds 34:04 Can humans adapt to the absence of a magnetic field? 35:29 Mitochondrial evolution, the microbiome and cancer 45:05 Therapeutic magnetic fields and non-linear effects 46:04 Power grids, magnetic exposure and confounding factors 52:09 The radical-pair mechanism and quantum biology 54:07 Geomagnetic storms and biological sensing 55:47 Grounding, atmospheric charge and magnetic flux 01:00:01 Final thoughts on geomagnetic reversal and spaceflight Follow the GUY FOUNDATION Website: https://www.theguyfoundation.org/ YouTube: https://youtube.com/@theguyfoundation X: https://x.com/GuyFoundation Follow DR MAX Website: https://drmaxgulhane.com/ Private Group: https://www.skool.com/dr-maxs-circadian-reset Courses: https://drmaxgulhane.com/collections/courses X: https://twitter.com/MaxGulhaneMD Instagram: https://www.instagram.com/dr_max_gulhane/ Apple Podcasts:  https://podcasts.apple.com/podcast/id1661751206 Spotify:  https://open.spotify.com/show/6edRmG3IFafTYnwQiJjhwR Linktree: https://linktr.ee/maxgulhanemd DISCLAIMER: The content in this podcast is purely for informational purposes and is not a substitute for professional medical advice, diagnosis, or treatment. Do not disregard professional medical advice or delay in seeking it because of something you have heard on this podcast or YouTube channel. Do not make medication changes without first consulting your treating clinician. #Magnetobiology #Geomagnetism #QuantumBiology #Mitochondria #MitochondrialHealth #EarthsMagneticField #SpaceHealth #CircadianBiology #Photobiology #InfraredLight #RadicalPairMechanism #ElectromagneticFields #ForestBathing #GeoffreyGuy #AlistairNunn #DrMaxGulhane #regenerativehealth Send us Fan Mail 🧡 HARDBLOCK Australia's Longest Running Bitcoin-only (₿) Exchange Use code REGENPOD for AUD 10 of bitcoin post account verification Support the show

  3. Jul 26

    107. Nitric Oxide, LDL and the Missing Link in Heart Disease | Peter Anderson

    Why can two people with similar LDL levels experience radically different cardiovascular outcomes?  In this episode, I speak with Peter Anderson about the possibility that endothelial nitric oxide may be one of the major variables separating these outcomes. We explore whether nitric oxide can be understood as a protective “bank” that is progressively depleted by ageing, hypertension, smoking, insulin resistance, obesity, sleep deprivation, psychological stress and circadian disruption. We also discuss dietary nitrate, rocket and beetroot, oral bacteria, sunlight, ultraviolet A, infrared light, movement, erectile function, flow-mediated dilation, ketosis, statins, calcium scores and the emerging controversy surrounding coronary CT analysis in lean-mass hyper-responders. CONSULT DR MAX 🩺 Comprehensive Health Consulting & second opinion - www.drmaxgulhane.com/consulting SUPPORT MY WORK 🎤 PRIVATE MEMBERS GROUP on Skool platform - weekly Q&A, my 52-page eBook, PDF resource downloads & more. USD20/month, cancel anytime.  https://www.skool.com/dr-maxs-circadian-reset 🚨 DAYLIGHT COMPUTER. Blue-light free computer that doesn't wreck your circadian rhythm. Now shipping around the world. Code DRMAX for $25 off.   https://buy.daylightcomputer.com/DRMAX 🚨 VIVA RAYS. Premium blue light blocking glasses with the most useful 3 in 1 clip on frame sets. Code DRMAX for 15% off. https://vivarays.com/dr-maxgulhane 🚨 GEMBA RED. Highest quality photobiomodulation / redlight therapy devices, shipping within the USA. Code DRMAX for 10% off. https://gembared.com TIMESTAMPS 04:38 Why similar cholesterol levels produce different outcomes 06:16 Nitric oxide, eNOS and the endothelial “bank” 09:00 How lipoproteins become retained in the arterial wall 13:50 LDL as a midstream rather than sole upstream factor 16:11 Lipid-lowering therapy and the “sledgehammer” problem 19:17 Atherosclerosis as a redox and endothelial disease 20:59 Flow-mediated dilation and real-time vascular assessment 26:20 Erectile dysfunction as an early vascular warning sign 28:19 Why standard lipid profiles can miss cardiovascular disease 31:19 Dietary nitrate and the DASH diet 33:36 Nitrate-rich food as vascular medicine 37:00 Citrulline, ageing and reduced eNOS function 40:25 Oral bacteria, mouthwash and blood pressure 41:40 Sunlight, skin nitrate stores and nitric oxide 43:48 Circadian regulation of eNOS 46:26 Shift work, melatonin and endothelial repair 50:22 Ketosis, beta-hydroxybutyrate and eNOS coupling 52:36 Traditional populations, movement and vascular health 57:53 Exercise, soft plaque and sudden cardiac events 01:03:42 When might statin therapy be appropriate? 01:11:27 The keto-CTA and lean-mass hyper-responder controversy 01:17:34 Studying people who regress plaque despite high LDL 01:21:37 Lipoprotein(a) and eNOS uncoupling 01:27:14 Infrared light, fourth-phase water and blood flow 01:33:52 Peter’s practical vascular-health framework Follow DR MAX Website: https://drmaxgulhane.com/ Private Group: https://www.skool.com/dr-maxs-circadian-reset Courses: https://drmaxgulhane.com/collections/courses X: https://twitter.com/MaxGulhaneMD Instagram: https://www.instagram.com/dr_max_gulhane/ Apple Podcasts:  https://podcasts.apple.com/podcast/id1661751206 Spotify:  https://open.spotify.com/show/6edRmG3IFafTYnwQiJjhwR Linktree: https://linktr.ee/maxgulhanemd DISCLAIMER: The content in this podcast is purely for informational purposes and is not a substitute for professional medical advice, diagnosis, or treatment. Do not disregard professional medical advice or delay in seeking it because of something you have heard on this podcast or YouTube channel. Do not make medication changes without first consulting your treating clinician. #NitricOxide #EndothelialHealth #Atherosclerosis #HeartDisease #CardiovascularHealth #LDLCholesterol #ApoB #EndothelialDysfunction #eNOS #Glycocalyx #LipoproteinRetention #CoronaryArteryDisease #VascularHealth #FlowMediatedDilation #DietaryNitrates #Beetroot #Rocket #Arugula #SunlightHealth #CircadianRhythm #ErectileDysfunction #BloodPressure #PlaqueStabilisation #CalciumScore #Statins #MetabolicHealth #InsulinResistance #OxidativeStress #KetoDiet #LeanMassHyperResponder #RegenerativeHealth #DrMaxGulhane #PeterAnderson Send us Fan Mail 🧡 HARDBLOCK Australia's Longest Running Bitcoin-only (₿) Exchange Use code REGENPOD for AUD 10 of bitcoin post account verification Support the show

  4. Jul 14

    106. Nguni Cattle, Regenerative Grazing and the Future of Food | Prof. Richard Fynn

    Are cattle inherently destructive—or have we simply built the wrong agricultural system around them? In this episode, Dr Max Gulhane speaks with Professor Richard Fynn, a rangeland ecologist and conservation scientist at the University of Botswana, about the future of beef production, regenerative grazing and indigenous African cattle. Professor Fynn explains why beef raised on diverse natural rangelands is fundamentally different from beef produced through grain-based feedlots. They explore how the phytochemical diversity of a cow’s diet may influence animal health, meat quality and flavour, as well as the broader consequences of feedlot production for animal welfare, biodiversity, soil carbon and the conversion of grasslands into cropland. The conversation then turns to Nguni and other indigenous African cattle. These animals have been shaped over generations by heat, drought, parasites, disease and nutritionally challenging landscapes. Their smaller frames, fertility, browsing ability and resilience may make them better suited to a hotter and increasingly variable climate than many large European-derived breeds. TIMESTAMPS 00:35 The Importance of Phytochemical Diversity in Animal Diets 03:24 Health Implications of Feedlot vs. Rangeland Beef 06:14 Consumer Awareness and Ethical Considerations in Meat Production 09:14 Environmental Impact of Feedlots vs. Sustainable Practices 11:48 The Role of Indigenous Breeds in Sustainable Agriculture 15:05 Adaptation of Cattle to Climate Change and Drought Conditions 18:04 The Economic Benefits of Indigenous Breeds 20:54 Case Studies and Personal Experiences with Nguni Cattle 23:55 Conclusion: The Future of Sustainable Beef Production 36:10 The Importance of Adaptation in Cattle Breeding 38:32 Genetic Resilience and Disease Resistance 41:32 The Impact of Foot and Mouth Disease 45:36 Grazing Management and Land Management Strategies 53:46 The Dangers of Selective Grazing 58:34 High Density Grazing and Its Benefits 01:03:41 The Future of Sustainable Beef Production 01:17:05 Moving Away from Feedlot Production FOLLOW RICHARD Contact rfynn@ub.ac.bw  Research Gate profile: https://www.researchgate.net/scientific-contributions/Richard-Fynn-2132304344 Grazing smarter: science-based grazing strategies, not only stocking rate, determine rangeland outcomes - https://www.tandfonline.com/doi/abs/10.2989/10220119.2025.2609078 FURTHER LISTENING ON NGUNI My Nguni interviews - https://www.youtube.com/playlist? list=PLrv4qp8WwfQG8lBXPL2BFx0sBAwA-jFbo AUSTRALIAN NGUNI BREEDERS  Henham Ngunis - https://www.henhamngunis.com.au/ Dr Gabriël Roux, Genesis Nguni - http://www.genesisnguni.com/ NGUNI COMMUNITY  Nguni Association of Australia - https://www.nguni.au/ Nguni Australia Instagram - https://instagram.com/nguni_australia Nguni Association of South Africa - https://nguni.co.za/ Nguni Facebook Group - https://www.facebook.com/groups/ngunicattle/ Nguni Australia Facebook Group -https://www.facebook.com/nguniaustralia Follow DR MAX Website: https://drmaxgulhane.com/ (SIGN UP TO MY EMAIL LIST) Private Group: https://www.skool.com/dr-maxs-circadian-reset Courses: https://drmaxgulhane.com/collections/courses Twitter: https://twitter.com/MaxGulhaneMD Instagram: https://www.instagram.com/dr_max_gulhane/ Apple Podcasts:  https://podcasts.apple.com/podcast/id1661751206 Spotify:  https://open.spotify.com/show/6edRmG3IFafTYnwQiJjhwR Linktree: https://linktr.ee/maxgulhanemd #nguni #regenerativefarming #regenerativeagriculture Send us Fan Mail 🧡 HARDBLOCK Australia's Longest Running Bitcoin-only (₿) Exchange Use code REGENPOD for AUD 10 of bitcoin post account verification Support the show

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About

I speak with world leaders on circadian & quantum biology, metabolic medicine & regenerative farming in search of the most effective ways of optimising health and reversing chronic disease.

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