Fat Science

Dr Emily Cooper

Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go (and stay!) away. In each episode, we share little-known facts and personal experiences to dispel misconceptions, reduce stigma, and instill hope. Fat Science is committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.

  1. 21h ago

    Understanding New Metabolic Medications and How They Work

    Metabolic medications work by mimicking natural gut hormones and brain signals, not just by slowing down the digestive tract. Dr. Emily Cooper, Mark Wright, and Andrea Taylor break down the rapidly evolving landscape of metabolic therapies. From oral options to high-dose formulations and pipeline molecules, the conversation cuts through public confusion to focus on biological mechanisms. The discussion explores how these therapies interact with complex melanocortin and hormonal pathways in the brain. Rather than relying on rigid protocols or escalating doses prematurely, effective metabolic care focuses on individual biological response and measurable health parameters. Key Takeaways Modern metabolic therapies are designed to mimic native hormones like GLP-1, GIP, and amylin rather than simply slowing gastric emptying. Clinical trial dosing sequences are designed for regulatory approval, while individualized clinical practice prioritizes symptom stability and health markers over reaching maximum doses. Health improvements such as blood pressure regulation, cholesterol shifts, and liver markers often occur independently of scale changes. Resources Mentioned Diabesity Institute Foundations Course Cooper Center for Metabolism Connect with Us Podcast Home:fatsciencepodcast.com Cooper Center for Metabolism:coopermetabolic.com Diabesity Institute: diabesityinstitute.org Resources from Dr. Cooper:coopermetabolic.com/resources Join Our Community:patreon.com/cw/FatSciencePodcast Submit Your Question: questions@fatsciencepodcast.com or dr.c@fatsciencepodcast.com Fat Science is supported by the Diabesity Institute, a nonprofit dedicated to increasing access to effective, science-based metabolic care. This podcast is for informational purposes only and is not intended as medical advice. Please consult with a qualified healthcare provider for personalized recommendations. Produced by: Podcast Impact Studio https://podcastimpactstudio.com

  2. Oct 12

    Mailbag: Why Calorie Deficits Stall Metabolism

    Wondering why weight stalls on treatment? Dr. Emily Cooper explains how the brain defends set points and why eating less stops progress. Dr. Emily Cooper, Mark Wright, and Andrea Taylor answer listener letters from around the world. The conversation addresses why athletic men with a BMI of 27 can still show high visceral fat on a DEXA scan, how medications defend metabolic set points, and why intentional undereating triggers starvation responses. The team also examines global access to metabolic treatments, dual incretin agonists versus single agonists, artificial sweeteners, and how to interpret two-hour insulin and glucose tolerance curves. Key Takeaways Rapid weight reduction without adequate nutrition can cause lean mass loss and trigger metabolic defense mechanisms.Dual incretin therapies stimulate GIP receptors far more than GLP-1 receptors compared to natural human hormones, creating different patient responses.Intentional calorie restriction reduces natural incretin production and can impair metabolic signaling, making mechanical fueling essential.Fasting insulin suppression combined with pre-diabetes indicators can reflect the brain pulling glucose during periods of low carbohydrate intake.Resources Mentioned Diabesity Foundations Course Cooper Center for Metabolism Diabesity Institute Connect with Us Podcast Home:fatsciencepodcast.com Cooper Center for Metabolism:coopermetabolic.com Diabesity Institute: diabesityinstitute.org Resources from Dr. Cooper:coopermetabolic.com/resources Join Our Community:patreon.com/cw/FatSciencePodcast Submit Your Question: questions@fatsciencepodcast.com or dr.c@fatsciencepodcast.com Fat Science is supported by the Diabesity Institute, a nonprofit dedicated to increasing access to effective, science-based metabolic care. This podcast is for informational purposes only and is not intended as medical advice. Please consult with a qualified healthcare provider for personalized recommendations. Produced by: Podcast Impact Studio https://podcastimpactstudio.com

  3. Sep 21

    Listener Spotlight: Alessio’s Metabolic Wake-Up Call

    Can metabolic dysfunction be the cause of anxiety? Join Dr. Emily Cooper, Andrea Taylor, and guest Alessio De Martis as they explore the fascinating intersection of metabolic health, anxiety, and the struggle with traditional diet advice. Learn how under-fueling can exacerbate metabolic issues and what that means for your overall health. KEY TAKEAWAYS Alessio's experience highlights the struggle of self-managing metabolic health in Europe.Under-fueling can worsen metabolic dysfunction, disrupting body stability.The body's response to hypoglycemia can mirror symptoms of anxiety. NOTABLE QUOTE "If you have a history of hypoglycemia, you're gonna have a lot less tolerance than other people." — Dr. Emily Cooper GUEST BIO Alessio De Martis is a 41-year-old listener from Rome, Italy, who shares his experiences with metabolic dysfunction, hypoglycemia, and anxiety. His journey represents the challenges faced by many in understanding their metabolic health. Links & Resources Podcast Home: fatsciencepodcast.com Cooper Center for Metabolism: coopermetabolic.com Resources from Dr. Cooper: coopermetabolic.com/resources Join Our Community: patreon.com/cw/FatSciencePodcast Submit Your Question: questions@fatsciencepodcast.com or dr.c@fatsciencepodcast.com Fat Science is supported by the Diabesity Institute, a nonprofit dedicated to increasing access to effective, science-based metabolic care. This podcast is for informational purposes only and is not intended as medical advice. Please consult with a qualified healthcare provider for personalized recommendations.

Hosts & Guests

4.6
out of 5
209 Ratings

About

Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go (and stay!) away. In each episode, we share little-known facts and personal experiences to dispel misconceptions, reduce stigma, and instill hope. Fat Science is committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.

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