Alzheimer’s Breakthrough with Dr. Josh Helman, MD

Dr. Josh Helman, MD
  • 4.7 (13)
  • ALTERNATIVE HEALTH
  • UPDATED WEEKLY

Welcome to Alzheimer’s Breakthrough with Dr. Josh Helman, MD, the transformative podcast that delves into the root causes of cognitive decline and provides real solutions for preventing—and even reversing—Alzheimer’s. Hosted by Dr. Josh Helman, MD, a Harvard-trained physician with advanced degrees in biochemistry, this show is designed for individuals living with Alzheimer’s, their loved ones, and anyone determined to preserve and improve brain health. Each week, Dr. Josh demystifies the complexities of dementia, unpacks the latest breakthroughs in neurodegenerative research, and shares actionable lifestyle strategies drawn from his six years of clinical experience reversing Alzheimer’s. From tackling nutritional deficiencies and toxin exposure to exploring cutting-edge diagnostics and mind-body interventions, Alzheimer’s Breakthrough with Dr. Josh Helman, MD, turns every challenge into an opportunity to reclaim cognitive vitality and hope. If you’re ready to discover evidence-based approaches that can restore mental clarity and empower you or your loved ones, tune in to Alzheimer’s Breakthrough with Dr. Josh Helman, MD, on Spotify, Apple Podcasts, or YouTube. Get ready to embrace a brighter future—one breakthrough at a time.

  1. 5H AGO

    Can Blood Filtration Reverse Post-Viral Inflammation and Brain Fog? With Dr. Mobeen Syed

    Can “blood filtration” act like an oil change for chronic inflammation? In this episode, Dr. Mobeen Syed, also known as Dr. Been, returns to discuss a hot topic in chronic inflammation and spike-related syndromes: therapeutic plasma exchange (TPE) and other blood filtration approaches. We break down what these procedures actually do, what they can remove from circulation, and why that might matter for brain fog, fatigue, microvascular dysfunction, and neuroinflammation. Dr. Been outlines the core methods: classic plasma exchange, immunoadsorption, and other extracorporeal options. We discuss the proposed “reset” effect, including reducing inflammatory mediators, autoantibodies, and abnormal clotting signals that may keep the body stuck in a vicious cycle. We review a sham-controlled randomized trial that found TPE to be safe but ineffective in that cohort, and discuss why a single intervention may help only a subset, if at all. If you want a clear, mechanism-first explanation without the hype, this conversation is for you. Share it with someone experiencing brain fog or fatigue, and subscribe for more evidence-based brain health deep dives. “Normally, the body is very efficient in removing extraneous harmful substances. When the body is unable to remove them because they are difficult to remove (like beta-pleated fiber sheets) and they are being produced a lot, we need to give the body a break. So we clean out the plasma.” ~ Dr. Mobeen Syed, MD, MSc In this Episode 00:00 - Introduction to Dr. Mobeen Syed, MD, MSc 03:16 - Dr. Been's opinion on the benefits of TPE 05:02 - Can we remove bad things from the blood? 11:44 - The core idea: dislodge first, filter after 24:04 - What the studies say about TPE 49:41 - Can TPE reverse the effects of chronic inflammation and spike protein? 53:58 - Clarification of concepts and terminologies discussed 1:02:17 - Key takeaway from today's episode Resources: - Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide - Therapeutic Plasma Exchange: Current and Emerging Applications to Mitigate Cellular Signaling in Disease - https://www.mdpi.com/2218-273X/15/7/1000 - Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin - https://pmc.ncbi.nlm.nih.gov/articles/PMC8381139/ - Functional autoantibodies against G-protein coupled receptors in patients with persistent Long-COVID-19 symptoms - https://pubmed.ncbi.nlm.nih.gov/33880442/ Connect with Dr. Mobeen Syed, MD, MSc: - Website - https://members.drbeen.com/courses - YouTube - https://www.youtube.com/@DrBeenMedicalLectures Connect with Dr. Josh Helman, MD: - Instagram - a href="https://www.instagram.com/greenbrainsMD" rel="noopener noreferrer"...

    1h 6m

  2. FEB 12

    How Regenerative Medicine Can Reverse Alzheimer's: A New Approach With Dr. Greg Carder

    If you’ve ever wondered whether there’s more to brain healing than just stem cells, you’re in for a fascinating conversation. Dr. Greg Carder, a leading expert in regenerative medicine, explains how regenerative signaling factors (RSFs) are proving to be a game-changer in reversing cognitive decline and Alzheimer's disease. It's not about adding more cells; it’s about delivering the right signals to the brain in the proper sequence. We also discuss the role of exosomes, the small particles that carry healing messages to damaged areas of the brain, and how this groundbreaking regenerative approach is providing new hope for those battling Alzheimer’s. Dr. Carder shares case studies demonstrating significant improvement in patients treated with these therapies. If you’re ready to explore how regenerative signaling is changing the landscape of Alzheimer’s treatment, you’ll want to hear Dr. Carder’s expert advice. Stay tuned to learn how to take proactive steps in brain health! “If I'm going to live in the world that I live in and I'm going to expose myself to these environmental toxins, then regenerative medicine needs to be a well-rounded and regular component of your hope to at least increase the quality of your life on a day-to-day basis.” ~ Dr. Greg Carder In this Episode 00:00 - Introduction to Dr. Greg Carder 03:43 - The importance of RSF for health optimization 07:30 - The role of stem cells in brain regeneration 12:12 - Exosomes and their benefit to our health 20:09 - The placenta as a rich source of MSCs 28:41 - The science behind RSF 32:55 - When not to use regenerative medicine 39:50 - How regenerative therapies can treat Alzheimer’s 43:51 - Case reports of how RSF helped different patients 50:15 - Prerequisites to using RSF on a patient 56:10 - Key takeaway from Dr. Carder 58:55 - Why some doctors are not offering RSF as a healing tool Resources: - Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide Connect with Dr. Greg Carder: - Website - https://regenmds.com/ and https://www.hydroheal.com/ - Instagram - https://www.instagram.com/hydroheal/# Connect with Dr. Josh Helman, MD: - Instagram - https://www.instagram.com/greenbrainsMD - Facebook - https://www.facebook.com/greenbrainsmd/ - LinkedIn - https://www.linkedin.com/in/doctorjosh - TikTok - https://www.tiktok.com/@greenbrainsmd - a...

    1h 8m

  3. FEB 5

    Mercury & Alzheimer’s: What Your Dentist Isn’t Telling You About Silver Fillings With Anita Vazquez-Tibau

    Could the silver fillings in your mouth be damaging your brain? In today’s episode, I interview Anita Vazquez-Tibau, an international advocate and researcher dedicated to ending the global use of toxic mercury in dentistry. Together, we dive into the shocking truth about dental amalgam fillings, which contain up to 54% mercury, a known neurotoxin. I was astounded to learn that despite the risks, the American Dental Association still claims that these fillings are safe. Anita explains how mercury not only poses a risk to your brain health but can also lead to neurodegeneration, including Alzheimer’s. We also discuss the global fight against mercury dental fillings, the Minamata Convention, and what you can do to protect your health if you have mercury fillings. If you or someone you love is dealing with cognitive decline, this episode could be an eye-opener. “The key is to have a good biological dentist who knows how to do oral surgery. Clean out everything and just say: Stop there. I don’t want an implant. I would like a removable appliance.” ~ Anita Vazquez -Tibau (How to Protect Yourself from Toxic Dental Implants) In this Episode 00:00 - Introduction to Anita Vazquez -Tibau 04:42 - Why the ADA still claims mercury fillings are safe 07:32 - The Minamata Convention and mercury regulation 20:19 - Mercury connection in Alzheimer’s and neurodegeneration 28:33 - The dangers of some dental procedures 38:42 - Detoxification, biocompatibility testing, and safe removal of mercury fillings 50:52 - Other sources of mercury that we may not be aware of 59:42 - Early signs of mercury exposure 1:04:31 - Why some industries still use mercury despite the risks 1:08:03 - The risks of getting titanium implants 1:13:32 - What to do next if you have mercury implants Resources: - Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide Mentioned in this episode: - This is an extremely important video on mercury and brain neurodegeneration - https://www.youtube.com/watch?v=XU8nSn5Ezd8 - The Smoking Tooth video - https://www.youtube.com/watch?v=X0QJWqtl6AI - Citizen Petition - https://www.regulations.gov/document/FDA-2025-P-2526-0001 - ANITA’s UNITED NATIONS CLOSING REMARKS MINAMATA CONVENTION COP6 - https://www.youtube.com/watch?v=ImoXCCAapXo - Book link, CHEW ON THIS - https://www.amazon.com/Chew-this-but-dont-swallow/dp/B09PZR2TQK/ Connect with Anita Vazquez -Tibau: - LinkedIn - a href="https://www.linkedin.com/in/anita-vazquez-tibau-6a85633/" rel="noopener noreferrer"...

    1h 24m

  4. JAN 29

    Can Plasma Exchange Slow or Reverse Cognitive Decline? A Conversation With Dr. Brad Younggren

    Alzheimer’s doesn’t begin with sudden memory loss. It begins decades earlier with systemic breakdowns that modern medicine continues to miss. And by the time someone is diagnosed with Alzheimer’s, the damage seems full-blown. In this episode, I sit down with Dr. Brad Younggren to discuss why Alzheimer’s is less a mystery of missing science and more a failure of how our healthcare system is designed. We explore therapeutic plasma exchange (TPE) and why removing harmful inflammatory proteins, immune antibodies, plastics, and toxic exposures from the bloodstream may represent a powerful new frontier in brain health, longevity, and chronic disease care. Dr. Younggren shares how this decades-old hospital procedure is being safely re-engineered for outpatient use and why it’s showing promise for dementia, autoimmune illness, and accelerated aging. We also discuss why the exposome, the total toxic burden from plastics, heavy metals, mold, and environmental chemicals, plays a far bigger role in cognitive decline than most people realize. From immune modulation to biological age reversal, this conversation challenges the idea that Alzheimer’s is inevitable or untreatable. If you care about preventing cognitive decline, extending brain healthspan, and understanding why the medical system often fails Alzheimer's patients, this episode opens your eyes to what’s possible. Interested in receiving TPE with Dr. Josh? Apply to work with him here: https://drjosh.com/work-with-dr-josh/ “If you reduce the toxic burden on the body, the brain has an incredible ability to heal itself.” ~ Dr. Brad Younggren In this Episode 00:00 - Introduction to Dr. Brad Younggren of Circulate Health 03:55 - A perspective on therapeutic plasma exchange (TPE) 05:53 - What TPE really is, how it works, and some benefits 15:28 - Immune recalibration and repeat plasma exchange 22:03 - Enhancing the TPE process 28:12 - Biological age reversal and proteomic clocks 31:23 - TPE for Alzheimer’s and dementia 36:37 - Circulate Health’s approach to conducting TPE 38:50 - Minimizing toxin exposure 42:53 - TPE use in emergency rooms and treating specific illnesses 49:29 - The future of TPE study and Circulate Health Resources: - Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide Connect with Dr. Brad Younggren: - Website - https://www.circulate.health/ - LinkedIn - https://www.linkedin.com/company/circulatehealth/ Connect with Dr. Josh Helman, MD: - Instagram - https://www.instagram.com/greenbrainsMD - Facebook - https://www.facebook.com/greenbrainsmd/ - LinkedIn - a...

    56 min

  5. JAN 22

    How Non-Invasive Spinal Stimulation Can Prevent Alzheimer’s and Improve Brain Health With Dr. Kyle Bills

    Could spinal stimulation be the key to preventing Alzheimer's and boosting brain health? In this episode, I'm joined by Dr. Kyle Bills, a neuroscientist, clinician, and innovator, to explore brain regulation, neural stimulation, and the nervous system's role in Alzheimer's prevention. We discuss the fascinating science behind his breakthrough device, The Neuronova Dopamine Chair, and how non-invasive spinal stimulation can improve cognitive function. Dr. Bills shares his experiences with patients, including those suffering from chronic migraines and anxiety, and how this technology has helped them regain mental clarity and balance. We also discuss the potential to enhance neurocognitive rehabilitation for traumatic brain injuries and the promising future applications of this technology. Listen in to learn how this cutting-edge device might revolutionize brain health, offering hope for those affected by neurodegenerative diseases. Want to try The Neuronova Dopamine Chair? Order here: https://neuro-nova.myshopify.com/DRJOSH (Use Code DRJOSH to get a 10% discount) “There is great power in being still and being intentional in what your thoughts and your mind do. That's a form of self-control that is highly underrated in today's society.” ~ Dr. Kyle Bills, DC, PhD In this Episode 00:00 - Introduction to Dr. Kyle Bills, DC, PhD 02:34 - What is the Neuronova device, and what was the idea behind it? 07:34 - Impact of non-invasive spinal stimulation on dopamine regulation 20:25 - Ten minutes a day is all it takes to experience positive results 34:36 - How the Neuronova chair is being used to improve people's health 42:06 - Neuronova's impact on patients with traumatic brain injury 52:30 - Why was the dopamine chair named Neuronova? 56:58 - The future of Neuronova in optimizing brain health Resources: - Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide Connect with Dr. Kyle Bills, DC, PhD: - Website - https://www.noordacom.org/bills-lab/ - Email - kyle.bills@noorda.edu Connect with Dr. Josh Helman, MD: - Instagram - https://www.instagram.com/greenbrainsMD - Facebook - https://www.facebook.com/greenbrainsmd/ - LinkedIn - https://www.linkedin.com/in/doctorjosh - TikTok - a href="https://www.tiktok.com/@greenbrainsmd" rel="noopener noreferrer"...

    1h 13m

  6. JAN 15

    Can a Plant-Based Diet Prevent Alzheimer’s? Dr. Michael Greger Explains the Science

    Did you know that populations that primarily eat plant-based diets have dramatically lower rates of dementia? In this episode, Dr. Michael Greger, a renowned physician and author, shares groundbreaking research on how nutrition, particularly plant-based diets, affects Alzheimer's prevention. We examine the science behind heart-healthy, brain-boosting foods, emphasizing the importance of a whole-food, plant-based diet for overall well-being. You’ll learn how simple dietary changes can alter the course of cognitive health and how the latest studies are reshaping our understanding of brain aging. Whether you’re looking to prevent Alzheimer’s or simply optimize your brain health, Dr. Greger offers actionable advice supported by decades of research. Tune in to discover how small changes in your diet can have a profound impact on your cognitive function and longevity. “Alzheimer's is related to the atherosclerotic buildup of plaque inside the intracranial arteries in the brain. So the same dietary changes that can help with cardiovascular health can also help with cognitive health. In other words, what's good for the heart is good for the head.” ~ Dr. Michael Greger, M.D. FACLM In this Episode 00:00 - Introduction to Dr. Michael Greger 02:28 - The importance of lifestyle for brain health 04:50 - How heart-healthy diets support brain health 06:40 - Practical tips for adopting a plant-based diet wherever you are 10:00 - The ketogenic diet debate 14:27 - How pollutants affect brain health 16:46 - The link between diabetes and Alzheimer's 22:04 - Dr. Greger's thoughts on lab testing 24:28 - Debunking common myths about plant-based eating 28:07 - How to stick to healthy habits 29:59 - Is fasting good for cognitive health? Resources: - Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide - How Not to Age by Dr. Michael Greger - https://nutritionfacts.org/book/how-not-to-age/ Connect with Dr. Michael Greger, M.D. FACLM: - Website - https://drgreger.org/ - Instagram - https://www.instagram.com/nutrition_facts_org/ - YouTube - https://www.youtube.com/@NutritionFactsOrg Connect with Dr. Josh Helman, MD: - Instagram - https://www.instagram.com/greenbrainsMD - Facebook - https://www.facebook.com/greenbrainsmd/ - a href="https://www.linkedin.com/in/doctorjosh" rel="noopener noreferrer"...

    32 min

  7. JAN 8

    Parasites, Toxins, and Alzheimer’s: Dr. Josh Helman’s Q&A Episode

    Do you have a brain health question you are afraid to ask? In this special Q&A episode, I’m answering the most pressing questions I receive about brain health, Alzheimer’s prevention, spike protein exposure, detoxification, parasites, fasting, and longevity. These are complex, often controversial topics, and my goal is to cut through fear, misinformation, and oversimplified advice with evidence-based clarity and real-world clinical experience. I explain what we currently know about spike proteins and what safe, physician-guided detoxification actually looks like. We explore glutathione as a foundational detox molecule, why overaggressively breaking down biofilms can backfire, and how lifestyle interventions can improve brain resilience even when damage has already occurred. This episode also dives into parasites, heavy metals, mold toxins, and how to separate legitimate detox science from marketing hype. I answer practical questions about fasting, antioxidants, supplements, affordability, and what truly moves the needle for protecting your brain long term. Most importantly, I want you to leave this conversation with hope. There is no single magic fix—but there is a powerful toolbox that can improve brain health, slow decline, and in many cases, support meaningful recovery. “You do not need lots of expensive boutique tests and exotic supplements to meaningfully protect your brain. Diet, exercise, cognitive training, and vascular risk management using low-tech components definitely improve cognition.” ~ Dr. Josh Helman In this Episode 00:00 - Introduction 00:51 - How can we detox spike proteins from the body? 07:35 - What are some things we can do to fix the damage from spike proteins? 09:24 - Why doesn't the spike protein affect everyone the same way? 26:18 - How can someone get mercury poisoning from a root canal? 27:52 - Are parasites really as widespread, or are the stories exaggerated? 34:51 - What is the difference between GLP-1 and human growth hormone receptors? 36:33 - How does fasting help prevent Alzheimer's, and what's the safest way to do it? 41:40 - How can the average person afford the expensive tests and supplements? 43:27 - What are the most affordable practical steps to protect brain health? 45:15 - How can listeners get reliable guidance without needing a consultation 52:25 - Can dogs get dementia or Alzheimer's, and can it be reversed? 54:37 - What do I personally do to improve my brain health and prevent decline? Resources: - Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide - Get reliable supplements at Dr. Josh Helman's Dispensary - https://drjosh.com/fullscript - Dr. Josh’s Favorite Products - https://drjosh.com/products/ Connect with Dr. Josh Helman, MD: - Instagram - a...

    1h 1m

  8. JAN 1

    Nutritional Secrets That May Help Prevent Alzheimer’s With Dr. Steve Blake

    Did you know the right combination of food, as well as vitamins and minerals, can potentially protect your brain from Alzheimer's? Today's guest reveals the science behind nutrition and brain health. In today’s episode, Dr. Steve Blake, an expert in nutritional neuroscience, joins me to discuss how specific vitamins, minerals, and omega-3 fatty acids play a crucial role in brain health and Alzheimer’s prevention. He shares fascinating insights into the importance of a nutrient-rich diet for supporting cognitive function and preventing neurodegeneration. Dr. Steve Blake also highlights the role of nutrition in optimizing brain structure and function, particularly as we age. We discuss practical ways to incorporate brain-boosting nutrients into your daily routine, how to identify deficiencies, and the key dietary changes that can significantly improve your cognitive health. If you’re looking to improve your brain health and reduce Alzheimer’s risk through nutrition, this episode is a must-listen. Dr. Steve Blake’s advice will empower you to take control of your cognitive health and make smarter, more informed food choices. “It's not just what we don't have in our diet but what we already are eating too much of in our diet that could impact the brain as well .” ~ Dr. Steve Blake, ScD In this Episode 00:00 - Introduction to Dr. Steve Blake 03:16 - Results from the Hawaii Dementia Prevention Trial 06:35 - The importance of a balanced diet for brain health 14:18 - The effect of reducing saturated fat in your diet 18:42 - Why vitamin B-12 and other nutrients are crucial for brain health 38:50 - More information about advanced glycation end products (AGEs) 40:03 - The role of omega-3s in cognitive function 43:19 - Is the ketogenic diet good for people with Alzheimer's? 54:58 - How lipopolysaccharides (LPS) affect our body 1:03:08 - Grains and how they contribute to our health 1:05:37 - Where to source organic food 1:07:03 - Other tips for boosting your brain health 1:12:14 - The future of nutrition studies in relation to brain health Resources: - Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide Connect with Dr. Steve Blake: - Website - https://drsteveblake.com/ - YouTube - https://www.youtube.com/@DrSteveBlakeScD - Email - Steve@drsteveblake.com Connect with Dr. Josh Helman, MD: - Instagram - https://www.instagram.com/greenbrainsMD - Facebook - https://www.facebook.com/greenbrainsmd/ - a href="https://www.linkedin.com/in/doctorjosh"...

    1h 18m
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About

Welcome to Alzheimer’s Breakthrough with Dr. Josh Helman, MD, the transformative podcast that delves into the root causes of cognitive decline and provides real solutions for preventing—and even reversing—Alzheimer’s. Hosted by Dr. Josh Helman, MD, a Harvard-trained physician with advanced degrees in biochemistry, this show is designed for individuals living with Alzheimer’s, their loved ones, and anyone determined to preserve and improve brain health. Each week, Dr. Josh demystifies the complexities of dementia, unpacks the latest breakthroughs in neurodegenerative research, and shares actionable lifestyle strategies drawn from his six years of clinical experience reversing Alzheimer’s. From tackling nutritional deficiencies and toxin exposure to exploring cutting-edge diagnostics and mind-body interventions, Alzheimer’s Breakthrough with Dr. Josh Helman, MD, turns every challenge into an opportunity to reclaim cognitive vitality and hope. If you’re ready to discover evidence-based approaches that can restore mental clarity and empower you or your loved ones, tune in to Alzheimer’s Breakthrough with Dr. Josh Helman, MD, on Spotify, Apple Podcasts, or YouTube. Get ready to embrace a brighter future—one breakthrough at a time.

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