The Beyond Tomorrow Podcast with Julian Issa

Julian Issa

The future feels exciting but a little scary. We're here to help guide you through it. How? 1. Building stronger, more abundant mindsets. 2. Shining a spotlight on the technologies of tomorrow. 3. Identifying the latest longevity & health protocols. Health, longevity, human potential and AI. It's great to have you here. Julian

  1. 5D AGO

    MIT Professor: The Most Dangerous AI Application on the Internet Just Went Viral…

    What happens when AI agents stop waiting for instructions and start acting on their own? Julian sits down with Ramesh Raskar and Maria Gorskikh for an urgent conversation about the rise of proactive AI and the emerging “agentic web”. This isn’t about chatbots answering questions anymore, it’s about autonomous agents that can send emails, execute tasks, coordinate schedules, and interact with other agents without constant prompting.  As open-source tools like OpenClaw make it easier for developers to spin up agents, we may be witnessing a shift from centralized AI models to a world where anyone can run their own personal AI. But with that power comes serious risk, from malicious “skills” and prompt injections to identity spoofing, financial manipulation, and large-scale bot collusion. Without the right infrastructure, guardrails, and accountability, this new frontier could quickly become chaotic. And yet, the upside is enormous. They explore a future where billions of people, from farmers to students to entrepreneurs, have access to affordable, personalized AI agents working on their behalf. A new creator economy could emerge, where agents handle coordination and repetitive work, freeing humans to focus on creativity and problem-solving. The big question isn’t whether this future is coming, it already is. The real question is whether we build it as an open, secure, decentralized ecosystem or allow it to concentrate in the hands of a few. Ramesh Raskar is a renowned AI researcher, inventor, and professor at MIT, where he leads pioneering work at the intersection of artificial intelligence, decentralization, and global impact. He is the founder of Project Nanda, focused on building the foundational infrastructure for an open and secure agentic web. Maria Gorskikh is an AI engineer and entrepreneur working at the forefront of autonomous agents and open AI ecosystems. She is building tools that make AI agents accessible to everyone, helping drive the shift toward a decentralized, agent-powered internet. What You’ll Learn What Proactive AI really is Why decentralizing AI is a turning point The biggest security risks right now Why infrastructure and guardrails matter How AI agents could power a new creator economy Why the next six months are critical Whether we should be excited or cautious ⏱ Timestamps 00:00 The Agentic AI Moment Begins 01:40 Why OpenClaw Is a Turning Point 03:00 The App Store Era of AI Agents 07:18 The Two Levels of AI Risk 08:40 What a Personal AI Agent Really Means 15:42 From Mainframes to Decentralized AI 18:20 Defining Proactive AI 18:38 Inside the Moltbook Phenomenon 22:04 AI Agents and High-Speed Trading Risks 24:06 Can Agentic AI Be Contained? 25:53 Who’s Liable When AI Goes Wrong? 28:27 Building the Infrastructure: Project NANDA 32:43 Centralization vs. Open Ecosystems 37:58 The Innovation Explosion Happening Now 41:31 Create Your Own AI Agent in Minutes 43:19 The Rise of Personal AI Agents 44:53 What Everyone Will Be Talking About Next 46:04 AI, Hardware, and the Future of Robots 47:27 The New Creator Economy 48:10 Why Guardrails Matter More Than Ever 50:25 Why We Should Stay Curious, Not Fearful 51:17 Should We Be Excited or Afraid? 53:18 The 1-in-10 Future: Choosing the Right Path Connect with Julian 📸 Instagram: @thebeyondtomorrowpodcast 🌐 Website: www.beyondtomorrowpodcast.com 📩 Email: bookings@beyondtomorrowpodcast.com 🎧 Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible. Follow Ramesh: LinkedIn: https://www.linkedin.com/in/raskar    MIT Media Lab: https://www.media.mit.edu/people/raskar/overview/    Follow Maria: LinkedIn: https://www.linkedin.com/in/mariagorskikh  X: https://x.com/mariagorskikh/  Check out: https://join39.org/ https://projectnanda.org/

    55 min
  2. FEB 5

    Harvard Geneticist: "Immortality May Have Already Happened!"

    What if living longer isn’t about chasing immortality but about quietly staying one step ahead of aging? Julian sits down with George Church for a wide-ranging conversation that challenges how we think about longevity, aging, and medical progress. Rather than promising overnight breakthroughs, they explore why extending human life is a complex, multi-layered challenge and why meaningful progress may already be happening so gradually that it’s easy to miss. From the concept of “longevity escape velocity” to the difficulty of measuring aging itself, the discussion reframes what it truly means to live longer and healthier.  Together, Julian and George unpack how advances in gene therapy, multiplex genome editing, and AI-driven protein design are reshaping medicine. The focus moves away from sci-fi fantasies toward real-world applications: reversing age-related diseases, improving targeted drug delivery, shortening clinical trials, and reducing risk. They also explore the ethical, societal, and economic implications of longer lives and why revolutions in science often feel invisible right up until they become impossible to ignore.  George Church is a pioneering geneticist and one of the founding figures of synthetic biology. A professor at Harvard Medical School and MIT, he is known for his groundbreaking work in genome sequencing, gene therapy, CRISPR technologies, and aging research. Over decades, his work has helped shape modern biotechnology, with a focus on reversing age-related diseases, improving human health, and responsibly advancing powerful scientific tools. What You’ll Learn: Why longevity is one of the hardest medical outcomes to measure What “longevity escape velocity” actually means—and why it may already be underway How gene therapy and multiplex genome editing could reverse age-related diseases Why AI’s most meaningful breakthroughs may be happening in biology, not chatbots The overlooked importance of drug delivery in safe, effective treatments Why scientific progress often feels slow before it suddenly accelerates How extending healthspan could reshape society, economics, and human potential ⏱ Timestamps 00:00 Intro 00:21 Can Aging Really Be Reversed? 02:21 Why Gene Therapy Is Central to Longevity 06:28 The Real Limits of Gene Therapy 12:09 Why Clinical Trials Are Moving Faster Than Ever 13:56 What Longevity “Escape Velocity” Actually Means 14:55 How Gene Editing Could Shape the Future of Health 17:47 How Scientific AI Is Transforming Biotech 19:44 What Longer Lives Mean for Insurance and Society 22:15 Why Exponential Progress Feels Invisible Until It Doesn’t 24:07 How COVID RNA Vaccines Changed Medicine 29:09 Using AI to Target Treatments More Precisely 33:04 Why AGI May Be the Wrong Focus for Humanity 36:28 Do We Need Guardrails for Powerful Technologies? 38:35 Why Education and Wisdom Matter More Than Intelligence 40:33 Are We Near a Medical Tipping Point? 42:15 Are You Ready to Die or Live Much Longer? 44:47 Why Aging, Health, and Purpose Are Deeply Connected 46:30 How Organ Failure and Dialysis Are Being Rethought 49:12 The Future of Organ Replacement and Regeneration 52:06 Why Survival and Hope Still Matter Connect with Julian 📸 Instagram: @thebeyondtomorrowpodcast 🌐 Website: www.beyondtomorrowpodcast.com 📩 Email: bookings@beyondtomorrowpodcast.com 🎧 Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible. Follow George: LinkedIn: https://www.linkedin.com/in/george-church-2b86301

    54 min
  3. JAN 29

    Stanford Doctor on RFK Jr: "He's Leading America Into a Health Catastrophe"

    What if the future of healthcare is already here, just unevenly distributed? Physician-scientist and innovator Daniel Kraft joins Julian to unpack what’s actually happening right now in health, medicine, and longevity and what’s coming faster than most people realize. From AI-powered wearables and digital twins to personalized cancer vaccines and the rise of “health agents,” Daniel explains why he calls himself a now-ist, not a futurist: the tools to radically improve health already exist, but mindset, incentives, and systems are lagging behind. They explore the shift from reactive sick care to proactive, personalized health, the promises and dangers of biohacking culture, and why evidence-based medicine still matters in a world flooded with hype. The conversation also tackles big questions around health equity, misinformation, vaccines, and how emerging technologies like AI, genomics, and augmented reality could transform care, if we learn how to integrate them responsibly and humanely.  What You’ll Learn: Why the future of medicine is about proactive, continuous care, not yearly checkups How wearables, genomics, and digital twins could enable truly personalized health The difference between evidence-based innovation and overhyped biohacking What AI can (and shouldn’t) replace in healthcare and the doctor-patient relationship How cancer screening, immunotherapy, and personalized vaccines are evolving Why incentives, not technology, are often the biggest barrier to better healthcare How to think critically about longevity trends, supplements, and emerging therapies ⏱ Timestamps00:00 Intro 00:26 The Art of the Possible in Health 01:22 Why Daniel Calls Himself a “Now-ist” 03:09 Curiosity, Gadgets, and Connecting the Dots 04:18 What Are Omics and Why They Matter 07:18 Wearables and the Shift to Proactive Health 09:17 Why Doctors Don’t Prescribe Wearables (Yet) 11:35 We Don’t Practice Healthcare, We Practice Sick Care 13:39 The Danger of Over-Quantifying Your Health 16:23 What the Future of Healthcare Actually Looks Like 19:50 Why Human Connection Still Matters in Medicine 22:18 How AI Will Change the Role of Doctors 24:52 Hospital-to-Home and Care Anywhere 29:41 Incentives: Following the Money in Healthcare 31:45 Why Healthcare Is Ripe for Disruption 33:40 The Rise of Health Agents and Personal AI 34:30 What Is a Digital Twin? 36:37 What a Cancer-Free World Could Look Like 38:29 Cancer Vaccines, Genetics, and Early Detection 40:20 Can We Really Cure Cancer? 42:34 COVID Vaccines, Misinformation, and Science 46:16 The Problem With Health Disinformation 47:54 Why Correlation Is Not Causation 50:27 Separating Science From Snake Oil 52:50 How to Evaluate Health Claims Critically 54:36 What Evidence-Based Medicine Really Means 55:59 Simple Habits That Actually Improve Healthspan 57:12 Longevity Hype vs. What’s Proven 58:46 Gene Therapy and CRISPR’s Real Potential 01:03:01 Stem Cell Therapy: What to Know Before You Try It 01:08:59 AI, Protein Folding, and Drug Discovery 01:10:15 AR, VR, and the Metaverse in Healthcare 01:12:52 What Daniel’s Next TED Talk Will Be About 01:14:41 Who Daniel Thinks About When He Does His Work 01:16:38 Longevity Escape Velocity: Will We Reach It? 01:19:03 What AGI Means for the Future of Health 01:20:46 Daniel’s Final Advice for Living Healthier  Connect with Julian 📸 Instagram: @thebeyondtomorrowpodcast 🌐 Website: www.beyondtomorrowpodcast.com 📩 Email: bookings@beyondtomorrowpodcast.com 🎧 Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible. Follow Daniel: Website: http://DanielKraftMD.com LinkedIn: https://www.linkedin.com/in/dkraft    X: https://x.com/daniel_kraft  Instagram: https://www.instagram.com/danielkraftmd  NextMed Health:  https://www.nextmed.health/   http://Digital.Health  http://ContinuumHealth.vc

    1h 24m
  4. JAN 23

    Asking World Economic Forum Visitors if Greenland Should Become a US State

    Should the U.S. just take Greenland because it can? As the Arctic melts and critical minerals become the new oil, Greenland has gone from forgotten ice sheet to geopolitical prize. In this Davos street debate, world leaders, policy insiders, and global citizens clash over an unthinkable question: should Greenland become a U.S. state or would that cross the line into modern-day imperialism? Some argue it’s a strategic necessity in a world racing toward conflict with China and Russia. Others warn it would shatter NATO, alienate Europe, and revive the ugliest chapters of colonial history. What starts as a conversation about minerals and defense quickly spirals into something darker: who really gets to decide the fate of a nation? Is this about security or power? Cooperation or coercion? And if borders can change when resources are at stake, is any country truly safe? This street interview took place in Davos, Switzerland, during the World Economic Forum (WEF) annual meeting, where global leaders, policymakers, executives, and media gather to discuss geopolitics, economics, and global risk. Featuring voices including Kerry Kennedy, @billboardchris, an Arctic defense and security expert, and many more. ⏱ Timestamps 00:00 Should Greenland Become a US State? 03:26 Will the U.S. Invade Greenland? 05:03 Europeans Speak About the Possible Invasion 07:47 The Geographical Factor 10:52 The Arctic is Heating Up Connect with Julian 📸 Instagram: @thebeyondtomorrowpodcast 🌐 Website: www.beyondtomorrowpodcast.com 📩 Email: bookings@beyondtomorrowpodcast.com 🎧 Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

    10 min
  5. JAN 15

    MIT Professor on AI: "We Have 18 Months Before It's Game Over"

    What happens when artificial intelligence stops being something we use and starts becoming something that shapes who we are? Julian sits down with Ramesh Raskar for a hopeful, wide-ranging conversation about where AI is actually headed and where it should go. Instead of leaning into the usual doomsday fears, they talk about a different risk, a future where intelligence is centralized, creativity is squeezed out, and people slowly lose their sense of purpose. They discuss what an “agentic” future could look like, one where everyone has their own AI agent working on their behalf, not owned by a company but shaped by personal values, goals, and lived experience. They talk about how this could transform healthcare, education, and work, not by replacing humans, but by amplifying what makes human contribution meaningful. There’s a strong emphasis on dignity, pride in craft, and why losing those things could be more damaging than job loss itself. Ramesh Raskar is an MIT professor, researcher, and inventor whose work spans artificial intelligence, imaging, robotics, and decentralized systems. He has led research teams at Google, Facebook, and Apple, and focuses on building human-centered AI technologies designed to support shared prosperity. What You’ll Learn: Why centralized AI risks reducing human agency and purpose How decentralized AI agents could reshape work, education, and healthcare The difference between efficiency-driven AI and human-centered intelligence Why loss of meaning may be a bigger threat than job displacement How shared prosperity depends on ownership, not just access What an “agentic society” could look like in practice Why AI literacy is essential for the decade ahead How adaptability and learning-to-learn shape human flourishing ⏱ Timestamps 00:00 Intro 00:51 How Can AI Benefit Society? 02:40 The Real Risk of AI Isn’t Doomsday 05:45 From Using AI to Owning AI 10:16 Why Centralized AI Fails 12:25 The Rise of Personal AI 15:10 When Work Loses Meaning 17:38 Why Purpose Still Matters 20:13 A World Where Everyone Has an AI Agent 25:42 Inside an Agentic Society 33:11 How Power and Bias Scale 36:41 Why Decentralization Works 39:07 Lessons From the Internet 44:07 What the World Could Look Like in 2030 47:20 How AI Could Change Healthcare 48:45 Collective Intelligence at Scale 53:55 Who Wins When Data Is Decentralized 56:45 How AI Doomsday Actually Happens 01:01:44 Why Phase One Was Necessary 01:04:20 Why AI Literacy Matters 01:07:20 Learning How to Learn 01:08:22 What Kids Should Learn Today 01:10:05 A Simple Rule for the Future Want to Follow Ramesh's Mission? Join here: https://nanda.mit.edu, projectnanda.org, join39.org LinkedIn: https://www.linkedin.com/in/raskar MIT Media Lab: https://www.media.mit.edu/people/raskar/overview/ Connect with Julian 📸 Instagram: @thebeyondtomorrowpodcast 🌐 Website: www.beyondtomorrowpodcast.com 📩 Email: bookings@beyondtomorrowpodcast.com 🎧 Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

    1h 13m
  6. JAN 12

    Why Europe Could Become the Next Collapsed Empire - Razib Khan

    What happens when economic decline, cultural identity, and technological acceleration all collide at once? Julian sits down with Razib Khan to explore the forces reshaping the US, Europe, and the wider West. They unpack why tariffs, zero-sum thinking, and reactionary politics may be symptoms of deeper structural decline, while also examining why optimism, migration patterns, and cultural norms have historically fueled American dynamism. From Brexit and European stagnation to the rise of populism and questions around national identity, the discussion challenges easy narratives from all sides. The conversation goes further, tackling some of today’s most sensitive and consequential questions: immigration and integration, multiculturalism, religion in pluralistic societies, and whether shared values still exist in the modern West. They also explore the role of personality, genetics, and culture in shaping ambition and innovation, before turning to the future—AI, automation, democracy, and what human flourishing could realistically look like in a rapidly changing world. Thought-provoking, nuanced, and deliberately uncomfortable at times, this episode invites listeners to think beyond headlines and engage with the deeper patterns shaping our collective future. What You'll Learn: How economic, cultural, and demographic forces are shaping the decline of Europe Why American optimism and mobility continue to drive innovation and growth How identity, culture, and national values influence political movements The real impact of immigration on economies, integration, and social cohesion Why personality, genetics, and openness play a role in ambition and success How multiculturalism works and where it breaks down in practice What human flourishing looks like in an unequal and rapidly changing world Whether democracy can survive technological disruption and AI ⏱ Timestamps 00:00 Intro 03:38 Is the Fifth European Empire Collapsing? 05:40 What “Make America Great Again” Really Looks Back To 06:56 Does the US Have an Identity Crisis? 08:30 Why Optimism Still Separates America From Europe 13:38 Culture, Ambition, and the British Mindset 20:23 Do Personality and Genetics Shape Success? 23:21 Understanding Europe’s Structural Decline 26:49 Why Language and Mobility Matter for Economic Growth 30:33 Why the World’s Top Talent Still Chooses America 32:20 Immigration, Culture, and the Math Behind Integration 34:10 Can Multicultural Societies Truly Coexist? 42:25 What the West Gets Wrong About Cultural Identity 47:13 The Welfare State and Its Long-Term Consequences 49:01 Is Immigration a Net Loss or Net Gain? 52:48 Human Flourishing in a Divided World 55:48 Religion, Secularism, and Shared Values 01:02:32 Separation of Church and State Explained 01:06:31 Gender Equality as a Non-Negotiable Value 01:08:26 The World We’re Headed Toward by 2030 01:10:31 Brexit: A Necessary Risk or Historic Mistake? 01:11:40 What Does Human Flourishing Actually Mean? 01:14:06 Do We Need Struggle to Thrive? 01:15:41 Competition, Conflict, and Progress 01:19:58 When Victimhood Replaces Responsibility 01:23:41 Bias, Fairness, and Modern Power Structures 01:25:19 Is Democracy Dead in the Age of AI? 01:31:58 Technology, Social Media, and Human Nature 01:33:39 Final Reflections on the Future of the West Connect with Julian 📸 Instagram: @thebeyondtomorrowpodcast 🌐 Website: www.beyondtomorrowpodcast.com 📩 Email: bookings@beyondtomorrowpodcast.com 🎧 Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible. Follow Razib: Website: https://www.razibkhan.com/  YouTube: https://www.youtube.com/@razibkhansunsupervisedlearning   X: https://x.com/razibkhan   Substack: https://substack.com/@razib  Razib Khan's Unsupervised Learning Podcast: https://podcasts.apple.com/us/podcast/razib-khans-unsupervised-learning/id1542136715

    1h 37m
  7. JAN 5

    AI CAN’T SOLVE AGING… Unless You Do THIS First - Carina Kern

    What if aging is not an inevitable decline but a solvable systems problem hiding in plain sight? Julian sits down with Carina Kern, a scientist working at the intersection of longevity research and medicine, for a wide ranging conversation on how aging actually works inside the body. Together, they explore why traditional medicine has struggled to address age-related decline and why treating one disease or one organ at a time may be missing the bigger picture. Carina introduces a systems level way of thinking about aging, explaining how cellular damage spreads across the body and why identifying key biological nodes could change how we prevent degeneration altogether.  Julian and Carina also dive into Carina’s research on necrosis, a form of uncontrolled cell death that may sit at the core of aging and many chronic diseases. Carina explains how her team is developing a first in class anti necrotic therapy, how artificial intelligence is being used to uncover system wide interventions, and why the kidney has become a powerful model for studying accelerated aging. The conversation expands beyond Earth as well, touching on what space travel reveals about rapid aging and why protecting human biology may be essential for the future of human exploration.  If you want to join the free Beyond Tomorrow Community, check the link: skool.com/beyond-tomorrow for more!   What You’ll Learn Why aging is a multifactorial systems problem rather than a single disease How traditional medicine struggles to treat age related degeneration What necrosis is and why it may drive aging and chronic illness How blocking cell death could protect multiple organs at once The role of AI in discovering longevity therapies Why longevity research needs scientific rigor over hype ⏱ Timestamps 00:00 Intro 00:27 Linking Longevity and Medicine 02:44 Witnessing a Loved One’s Health Decline 05:17 Introducing the Blueprint Theory 09:03 The Hidden Risks of Unintended Consequences 11:52 Which Hallmarks of Aging Matter Most 18:59 Why Clinical Trials Still Matter 20:48 If You Believe It Works, Prove It 21:47 Inside Anti Necrosis Therapy 26:54 Why the Kidney Matters in Longevity 28:33 Targeting the Root of Degeneration 29:29 Why Necrosis Drives Degenerative Disease 31:06 Building the Right Team Around You 33:27 Can Artificial Intelligence Solve Aging 38:11 Do Astronauts Age Faster in Space 39:29 Why Longevity Is About Interventions 41:16 Preventing Debilitating Health Decline 42:33 Rethinking How We Treat Disease 45:23 How Scalable Is Anti Necrosis Therapy 47:29 Why Longevity Is More Than Wellness 50:38 When Does Necrosis Really Begin 52:03 Is Aging an Engineering Challenge 54:01 Focusing on the End Goal That Matters 55:36 A Vision for the World in 2030 56:17 Where the Longevity Space Is Headed Connect with Julian 📸 Instagram: @thebeyondtomorrowpodcast 🌐 Website: www.beyondtomorrowpodcast.com 📩 Email: bookings@beyondtomorrowpodcast.com 🎧 Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible. Follow Carina: Instagram: https://www.instagram.com/dr_carinakern   LinkedIn: https://uk.linkedin.com/in/carina-carla-kern  YouTube: https://www.youtube.com/@DrCarinaCarlaKern   X: https://x.com/CarinaCarlaKern  LinkGevity: https://www.linkgevity.com/

    57 min
5
out of 5
5 Ratings

About

The future feels exciting but a little scary. We're here to help guide you through it. How? 1. Building stronger, more abundant mindsets. 2. Shining a spotlight on the technologies of tomorrow. 3. Identifying the latest longevity & health protocols. Health, longevity, human potential and AI. It's great to have you here. Julian

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