The Beyond Tomorrow Podcast with Julian Issa

Julian Issa
  • 4.4 (5)
  • Life Sciences
  • Updated Weekly

The future feels exciting but a little scary. We're here to help guide you through it. How? 1. Building stronger, more abundant mindsets. 2. Shining a spotlight on the technologies of tomorrow. 3. Identifying the latest longevity & health protocols. Health, longevity, human potential and AI. It's great to have you here. Julian

  1. 4d ago

    Dr Mike Israetel: ‘’ALMOST EVERY American Should Be On GLP-1s, Here’s Why!’’

    What if vanity was actually the smart way into a longer, healthier life? This episode is brought to you by AgelessRx, where aging becomes a puzzle that can be solved. Their mission is to help you live longer and healthier by adding more life to your years through science-backed solutions and personalized care. Learn more at agelessrx.com/beyond-tomorrow. On this episode of Beyond Tomorrow, Dr. Mike Israetel breaks down what's actually happening in his own bloodstream: 5mg/week of tirzepatide year-round, plus retatrutide during fat-loss phases, and why he thinks “GLP-2” is a gray-market marketing term with no basis in real receptor biology. He walks through the non-weight-loss case for these drugs, reduced systemic and neural inflammation, better glucose control, emerging anti-cancer data, and a documented drop in addictive behaviors from gambling to alcohol to cigarettes, before getting honest about the tradeoffs: undernutrition, anhedonia, and a long-term data set that, by his own admission, will never be “complete enough” for some critics. From there the conversation moves into gray-market peptides, why Mike separates his own risk tolerance from what he'd recommend to the public, and why there currently isn't a single peptide he'd recommend for muscle growth despite the demand. The back half covers his real thesis: that appearance, not health, is the most reliable motivator most people actually respond to and that chasing it tends to produce the same outcomes doctors have failed for decades to sell through fear. Key Takeaways Mike takes tirzepatide (Zepbound/Mounjaro) year-round at 5mg/week and adds retatrutide during cutting phases, both well within studied dose ranges He argues most GLP-1 “anhedonia” is caloric-deficit anhedonia, not a direct drug effect, the same thing bodybuilders experience on any aggressive diet New aggregate mortality data shows older adults on GLP-1s die less than those who aren't, which he says partially answers the “but will it kill you later” question There is currently no peptide he'd recommend for muscle growth, a claim he says consistently disappoints people who ask His core argument: use appearance as the entry point (build muscle, lose fat, sleep better) and let the longevity benefits follow, rather than trying to motivate people with 30-years-out health outcomes Timestamps 00:00 Intro 00:10 Is GLP-1 a Bad Idea? 08:55 The Seatbelt Analogy for Drugs 10:30 The Peptide That's Not FDA-Approved Yet 11:30 Exactly What Mike Takes Every Week 13:59 Stacking Peptides: an N-of-1 Experiment 15:11 Why Mike Takes Anabolic Steroids 16:42 The Drug That Could Replace Steroids 18:48 Why Mike Takes Tirzepatide and Retatrutide 21:45 20-Year Life Extension 25:34 Mike's Full Daily Stack 30:47 The Looksmaxxing Trojan Horse 35:35 Sick Care vs. Health Care 38:14 Three Exercises You Can Do Today 40:36 Critiquing Brian Johnson's Protocol 43:31 Is There a One-Size-Fits-All Workout? 46:06 Zone 2 vs. Zone 5 Training 52:21 Why Most Biohacking Is a Waste of Money 54:01 Is HIIT Still the Rage? 57:09 Escaping Poverty, Fueling Success 01:04:53 Why People Take Extreme Measures to Look Good 01:08:24 Moving Past GLP-1 01:14:52 Everyone Will Look 22 by 2037 01:18:24 Would You Date a 90-Year-Old? 01:24:52 Beauty Standards in a Post-GLP-1 World 01:25:37 The Cybernetic Revolution 01:28:25 Living Forever in a Robot Body 01:36:29 Will AI Cause Human Extinction? 01:43:28 The Biggest Myth About Weight Loss 01:44:02 Rapid Fire Questions with Mike 01:48:06 Mike's Best Piece of Advice Connect with Mike: Website: rpstrength.com/ Facebook: facebook.com/michael.israetel Instagram: @drmikeisraetel X: @misraetel Connect with Julian Instagram: @thebeyondtomorrowpodcast / @juliankissa LinkedIn: julian-issa X: @juliankissa Website: www.beyondtomorrowpodcast.com Email: bookings@beyondtomorrowpodcast.com

  2. Sep 17

    AI Safety Expert Roman Yampolskiy WARNS About the TWO Likely Endings with AI

    What happens when the technology we build becomes smarter than the people who built it? This episode is brought to you by AgelessRx, where aging becomes a puzzle that can be solved. The mission is to help you live longer and healthier by adding more life to your years through science-backed solutions and personalized care. Learn more at http://agelessrx.com/beyond-tomorrow AI safety researcher Roman Yampolskiy argues the real danger isn't AI, it's building a superintelligence we can no longer control. His case: solve problems with narrow, powerful tools instead, and still get breakthroughs in medicine, science, and productivity, without that risk. The conversation covers AGI, recursive self-improvement, the singularity, and the existential and "suffering" risks they raise, plus what mass automation could mean for work and purpose. From international AI agreements to human longevity, one question runs through it all: can we get the benefits of advanced AI without losing control of it? Yampolskiy's answer: keep building tools, not our replacement. Roman Yampolskiy is an AI safety researcher and professor who studies the risks and implications of artificial intelligence. His work focuses on the challenge of controlling increasingly capable AI systems and the potential consequences of superintelligence. Roman’s book, AI: Unexplainable, Unpredictable, Uncontrollable, explores the various reasons why the field is so challenging. ⏱ Timestamps 00:00 Intro 00:43 Can We Build AI By Design to Avoid Catastrophe? 01:49 AI Superintelligence Is a Death Sentence 03:12 What Is AGI, Really? 04:26 OpenAI's Plan to Build an Internal AGI 04:59 Why Superintelligence Won't Care About Us 06:45 We're Going to Die Anyway... So What? 07:06 We Can't Control Something This Advanced 07:55 The Narrow Tools That Avoid AGI 09:34 The US vs China AI Race 10:47 Does China Actually Want to Stop AGI? 11:53 AGI Is a Spectrum, Not a Switch 12:22 Is Roman Selling the Doom Narrative? 14:13 How to Stop AGI From Escaping the Box 16:26 Building AI We Can't Control 18:05 Suffering Risks: The Worst-Case Scenario 20:09 The Two Types of Jobs 22:09 What Happens to the 90% Who Lose Their Jobs? 23:46 Nothing Makes AI Labs Stop 24:26 Building Something You Can't Control 26:06 Do You Believe in God? 29:28 Longevity Escape Velocity Without AGI 30:55 Is Suffering Necessary for the Human Story? 31:33 Are We Living in a Simulation? 32:12 You Can't Control Superintelligence 33:24 Is Our Life a Simulation? 35:05 Curing Aging With Narrow AI Tools 36:10 What Is an NPC? 36:37 Could Humans Cause Doom Before AI Does? 37:21 How to Break Out of a Simulation 39:14 Would You Live Forever in a Simulation? 40:01 Don't Build Superintelligence 41:50 Bostrom's Singleton Theory 43:17 "AI Is Massively Overhyped" 44:56 Would AI Doom Be Worse Than World War 3? 45:41 Who Should You Actually Be Listening To? 47:43 What Would a Perfect Simulation Look Like? 50:52 Solving Longevity Without AI 52:03 Our Limited Understanding of Human Biology 52:40 What Makes Roman Happy? 53:48 Signs Governments Are Waking Up 55:14 "Is AI Just a Con?" 56:53 Can Squirrels Control Humans? 58:27 Decide What to Do With Your Time 59:22 What About Ilya Sutskever? 01:00:13 The Responsible Use of Technology 01:00:46 If Tomorrow is Your Last Day... Connect with Roman:  Website: https://www.romanyampolskiy.com/  Facebook: https://www.facebook.com/roman.yampolskiy/  LinkedIn: https://www.linkedin.com/in/romanyam/  X: https://x.com/romanyam  Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/   Instagram: https://www.instagram.com/juliankissa/   LinkedIn: https://uk.linkedin.com/in/julian-issa   Website: www.beyondtomorrowpodcast.com  Email: bookings@beyondtomorrowpodcast.com  Get exciting updates from The Beyond Tomorrow Podcast here: https://dlogos.xyz/podcasts/the-beyond-tomorrow-podcast-with-julian-issa-7bf16e9d

  3. Sep 15

    BT Clip: Longevity Experts: The Tipping Point That Will Trigger a Global “War on Aging” (Matt Kaeberlein, Aubrey de Grey, and Gordan Lauc)

    Let's get into the rapidly evolving future of longevity, from the moment society finally believes aging is solvable to the possibility of humans routinely living far beyond today’s lifespan — even approaching 150 years. Matt Kaeberlein, Aubrey de Grey, and Gordan Lauc explore how breakthroughs in aging science could also extend the lives of companion animals, while exposing how bad science and misallocated resources continue to slow meaningful progress. It’s a grounded, forward-looking discussion on what true longevity innovation requires. Watch the full episode here: https://open.spotify.com/episode/1Rmtl7sqoFOWolXWV6O22U?si=cd176f6a28404b4d

  4. Sep 10

    DAVID EAGLEMAN: The END of Human Presidents is COMING. Should We Worry?

    Could an AI actually run the country better than a person could? This episode is brought to you by AgelessRx, where aging becomes a puzzle that can be solved. The mission is to help you live longer and healthier by adding more life to your years through science-backed solutions and personalized care. Learn more at http://agelessrx.com/beyond-tomorrow David Eagleman doesn't shy away from the question. He lays out the case for an AI president, one that could crunch more data than any human cabinet, sidestep the ego and grudges that shape so many political decisions, and maybe even out-think our worst instincts. Sounds great, until you ask the harder questions. Who writes the code that decides what "the greater good" means? Can a machine actually be moral, or just really good at faking it? And if an AI ever did hold real power, who's holding the leash? We get into all of it: democracy, tribalism, consciousness, and how close we actually are to AGI. David doesn't pretend to have it all figured out but he makes a compelling case that the ground is shifting faster than most of us realize. David Eagleman is a neuroscientist at Stanford University and an internationally bestselling author. He is co-founder of several neurotech companies, including Jojo, BrainCheck, and Neosensory, and he also directs the Center for Science and Law, a national non-profit institute. He is best known for his work on sensory substitution, time perception, brain plasticity, synesthesia, and neurolaw. ⏱ Timestamps 00:00 Intro 00:05 Are We in the Middle of AGI? 03:26 AI’s Greatest Advantage 04:25 The Case for a Utilitarian AI President 07:16 Who Defines AI’s Parameters? 09:06 The Danger of Politically Biased AI 11:49 Behind the Scenes 12:33 Are We Ready for an AI President? 14:41 What Should an AI Government Optimize For? 18:31 How Soon Could We Have an AI President? 22:24 The Trolley Problem and AI Morality 27:54 What Happens When Humans Have Too Much Free Time? 29:07 The Neuroscience of Tribalism 30:13 The Neural Basis of Empathy 31:24 Why We’re Wired for Us vs. Them 32:43 Can AI Become Conscious? 33:51 Could AI Eradicate Humanity? 35:51 Artificial Wisdom and AI Guardrails 38:57 AGI Is Already Happening 41:22 An AI President in Our Lifetime 43:26 The Biggest Fear About AI Connect with David:  Website: https://eagleman.com/  Facebook: https://www.facebook.com/David.M.Eagleman  LinkedIn: https://www.linkedin.com/in/davideagleman/  Instagram: https://www.instagram.com/davideagleman  X: https://x.com/davideagleman  TikTok: https://www.tiktok.com/@drdavideagleman   Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/   Instagram: https://www.instagram.com/juliankissa/   LinkedIn: https://uk.linkedin.com/in/julian-issa   Website: www.beyondtomorrowpodcast.com  Email: bookings@beyondtomorrowpodcast.com  Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

  5. Sep 8

    BT Clip: Harvard Geneticist: "Immortality May Have Already Happened!" (George Church)

    What if immortality didn’t arrive as a single breakthrough but quietly, step by step?In this clip, George Church explains the idea of “longevity escape velocity”: the point where medical progress extends life faster than we age. If each generation of therapies buys us more time to develop the next, the path to dramatically longer lives or even practical immortality may already have begun.Watch the full episode here: https://open.spotify.com/episode/0c2x5fNYLSzvvfIil3c7WK?si=854bb724225e4136

  6. Sep 3

    Peter Diamandis: "AGI Is Already Here - They Just Haven't Released It Yet"

    What if the Singularity isn’t coming but already here? This episode is brought to you by AgelessRx, where aging becomes a puzzle that can be solved. The mission is to help you live longer and healthier by adding more life to your years through science-backed solutions and personalized care. Learn more at http://agelessrx.com/beyond-tomorrow AI is accelerating breakthroughs across science, medicine, and technology at a pace once considered impossible. Peter Diamandis believes the next 5–10 years could redefine what humanity can achieve. Yet AI’s promise is competing with fear, disruption, and dystopian narratives. The challenge is not only building the future, but shaping how people imagine it. For Peter Diamandis, the answer is actionable optimism: identify the risks, believe they can be solved, and pursue the biggest moonshots. Longevity, education, and space could become the foundations of a radically different future. Peter Diamandis is an entrepreneur, physician, and founder of XPRIZE and Singularity University. He is a leading advocate for moonshot thinking and breakthrough technologies. ⏱ Timestamps 00:00 Intro 00:10 The Blinding Speed of Change 02:06 A Future Where Anything Is Possible 04:06 Why Is the West Afraid of AI? 08:39 Why Fear AI? 10:23 AGI Is Already Here 11:37 Blind Optimism vs. Actionable Optimism 13:01 The Next Great Moonshot 14:01 The Rise of an Alien-Looking Economy 15:10 Who Will Win the XPRIZE? 15:46 If Tomorrow Was Your Last Day... Connect with Peter:  Website: https://www.diamandis.com/  Facebook: https://www.facebook.com/PeterDiamandis/ LinkedIn: https://www.linkedin.com/in/peterdiamandis/ Instagram: https://www.instagram.com/peterdiamandis X: https://x.com/peterdiamandis YouTube: https://www.youtube.com/@peterdiamandis  Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/   Instagram: https://www.instagram.com/juliankissa/   LinkedIn: https://uk.linkedin.com/in/julian-issa   Website: www.beyondtomorrowpodcast.com  Email: bookings@beyondtomorrowpodcast.com  Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

  7. Sep 1

    BT Clip: AGI Pioneers: ChatGPT Won’t Get Us to AGI.. Here’s What Will (Ben Goertzel)

    Are large language models like ChatGPT and Claude enough to create AGI?In this clip, Ben Goertzel explains why today’s LLMs are incredibly powerful, but still fundamentally different from true artificial general intelligence.He argues that simply building a bigger version of ChatGPT or Claude is unlikely to produce human-level AGI. Instead, reaching AGI will require new AI architectures that can go beyond their training, generalize to unfamiliar problems and make genuinely novel leaps in reasoning.Ben also explains why current models can already outperform humans in areas like coding, mathematics and knowledge retrieval, while still struggling with the kind of imagination and general intelligence humans use to push beyond existing knowledge. Full episode here: https://open.spotify.com/episode/7wGN1x0vQQgdzoktHipqBK?si=454702357d55415e

  8. Aug 28

    Ben Goertzel: Whoever Gets AGI First Can CONQUER THE PLANET

    How close are we to AGI? This episode is brought to you by AgelessRx, where aging becomes a puzzle that can be solved. The mission is to help you live longer and healthier by adding more life to your years through science-backed solutions and personalized care. Learn more at http://agelessrx.com/beyond-tomorrow The race toward AGI is entering a new phase. Ben Goertzel explores alternative paths to intelligence beyond simply building bigger models. The conversation also examines the global AI race. The U.S. and China are competing for technological leadership. But the future of AI may not remain centralized. Then comes the bigger question: what happens after superintelligence? Goertzel imagines AI that could protect humanity. It could even help overcome aging, disease, and other human limitations. Ben Goertzel is an AI researcher, futurist, and CEO of SingularityNET and BGI Labs. Widely recognized as one of the pioneers of Artificial General Intelligence, he has spent more than two decades developing decentralized AI systems designed to benefit humanity. What You’ll Learn Why the AI revolution may be bigger than previous technological shifts How AI could become an extension of human intelligence Why agency may matter more than machine consciousness How the brain creates a simulated model of reality Whether consciousness could emerge on different substrates Why AI alignment is also a problem of human alignment How AI could help humanity become smarter and more coherent ⏱ Timestamps 00:00 Intro 00:07 What Happens in the Next 12 Months? 03:41 Why China Is Catching Up 07:36 Why China Wants AI Control 10:18 Can Governments Control AI? 13:02 Human-Level AGI vs Superintelligence 15:35 Will ASI be Chinese or American? 17:47 The Next Breakthrough to AGI 21:05 How AI Could Become More Intelligent 22:23 Why Language Powers AI 27:33 Can Decentralized AI Change Everything? 32:23 The Global Race vs Decentralized AI 36:22 Would Superintelligence Protect Humanity? 40:19 Can We Build Compassionate AGI? 46:27 Why AI Arms Races Are Dangerous 51:14 Why Governments Shouldn’t Control AI 53:17 Can the Government Keep Up With AI? 54:00 Will Open AI Challenge Big Tech? 55:12 The Future of Decentralized AI 56:27 Could 2045 Arrive by 2028? Connect with Ben Website: https://singularitynet.io/  LinkedIn: https://www.linkedin.com/in/bengoertzel  X: https://x.com/bengoertzel  Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/   Instagram: https://www.instagram.com/juliankissa/   LinkedIn: https://uk.linkedin.com/in/julian-issa   Website: www.beyondtomorrowpodcast.com  Email: bookings@beyondtomorrowpodcast.com  Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

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The future feels exciting but a little scary. We're here to help guide you through it. How? 1. Building stronger, more abundant mindsets. 2. Shining a spotlight on the technologies of tomorrow. 3. Identifying the latest longevity & health protocols. Health, longevity, human potential and AI. It's great to have you here. Julian

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