Resiliency Radio with Dr. Jill Carnahan, MD

Dr. Jill Carnahan
  • 4.9 (57)
  • Alternative Health
  • Updated Weekly

Dr. Jill Carnahan, MD, ABIHM, ABoIM, IFMCP is a globally recognized leader in functional and integrative medicine, specializing in complex chronic illness, environmental toxicity, immune dysfunction, and resilience-based healing. She is dually board-certified and the founder and Medical Director of Flatiron Functional Medicine in Colorado, where she practices personalized precision medicine using advanced diagnostics and systems-based, root-cause care. A survivor of breast cancer, Crohn's disease, and severe mold-related illness, Dr. Jill brings both scientific expertise and lived experience to her work—bridging cutting-edge medical research with compassionate, patient-centered care. Her clinical approach focuses on restoring physiological resilience, optimizing immune and metabolic function, and supporting long-term health through individualized, evidence-informed protocols. Dr. Jill is the best-selling author of Unexpected: Finding Resilience Through Functional Medicine, Science, and Faith and the executive producer and featured physician in the award-winning documentary Doctor/Patient, which explores the future of medicine through the lens of healing, personalization, and human connection. As host of Resiliency Radio, Dr. Jill engages leading experts in functional medicine, longevity science, neuroscience, nutrition, environmental health, spirituality, and human performance. Each episode translates complex research into practical insights to help listeners build resilience, improve healthspan, and thrive in the face of modern health challenges. A sought-after international speaker, educator, and mentor, Dr. Jill is known for making advanced medical science accessible, hopeful, and actionable—delivered with clarity, compassion, and authenticity. Follow @drjillcarnahan for podcasts, research-backed education, articles, and resources. Disclaimer: This podcast is for educational purposes only and does not provide individual medical advice. Please consult your healthcare provider for personal medical care.

  1. 7h ago

    333: Resiliency Radio with Dr. Jill: Vision as a Gateway: How to Optimize Focus & Resilience with Dr. Meenal Agarwal

    In this episode of Resiliency Radio with Dr. Jill, Dr. Jill Carnahan welcomes board-certified optometrist and spatial awareness expert Dr. Meenal Agarwal for a fascinating look at how our eyes can provide a window into brain health, cognitive function, metabolic health, and overall resilience. Drawing from her own childhood diagnosis of glaucoma, Dr. Agarwal explains why healthy vision goes far beyond seeing 20/20. Together, they explore the relationship between the retina and brain, the effects of excessive screen time, peripheral vision and spatial awareness, blue light, cognitive decline, and emerging tools such as Optical Coherence Tomography (OCT). Most importantly, Dr. Agarwal shares practical strategies—from morning sunlight and the 20-20-20 rule to nutrition and outdoor movement—that can help protect vision, sharpen focus, and support lifelong brain health. 🔑 5 Key Discussions ① 👁️ The Eyes as a Window Into Brain & Systemic Health ⇨ The retina is embryologically brain tissue, while the optic nerve is part of the central nervous system, creating a powerful connection between vision and neurological health. ⇨ Because the eyes contain a dense vascular network, changes in eye health may provide valuable clues about metabolic dysfunction, vascular health, and neurodegenerative processes. ② 🧠 Why Healthy Vision Goes Beyond 20/20 ⇨ A standard 20/20 eye test evaluates only a small central portion of vision and doesn't capture the full picture of visual function. ⇨ Peripheral vision and spatial awareness engage important areas of the brain involved in navigation, problem-solving, movement, and our ability to interact confidently with the world around us. ③ 📱 Screen Time, Blue Light & the "Flat World" ⇨ Constant close-up screen use keeps the visual system focused on a flat, narrow environment and may contribute to eye strain and reduced engagement with peripheral vision. ⇨ Dr. Agarwal explains that blue light itself isn't proven to cause diseases such as glaucoma, but prolonged screen exposure can contribute to visual fatigue and disruption of healthy visual habits. ④ 🥬 Protecting Vision Through Everyday Habits ⇨ Morning sunlight helps regulate circadian rhythms, neurotransmitters, hormones, and healthy wakefulness. ⇨ The 20-20-20 rule—every 20 minutes, look approximately 20 feet away for 20 seconds—gives the eyes a break from sustained near-focus. ⇨ Leafy greens rich in lutein and zeaxanthin, antioxidant-rich berries, and omega-3 fatty acids can provide nutritional support for retinal and overall eye health. ⑤ 🔬 Vision, Cognitive Decline & the Future of Eye Exams ⇨ Poor or uncorrected vision may compound cognitive challenges by reducing the quality of information being delivered to and processed by the brain. ⇨ Technologies such as Optical Coherence Tomography (OCT) allow clinicians to examine detailed retinal structures and may become increasingly valuable in identifying changes associated with neurological and neurodegenerative disease. ⭐ Key Takeaways 🔹 Vision health is closely connected to brain, vascular, metabolic, and neurological health. 🔹 Seeing 20/20 doesn't necessarily mean your entire visual system is functioning optimally. 🔹 Peripheral vision and spatial awareness are important components of cognitive function and resilience. 🔹 Excessive close-up screen use can contribute to visual fatigue and limit engagement with the wider environment. 🔹 Natural morning light can support both circadian rhythm and healthy brain function. 🔹 Follow the 20-20-20 rule to reduce the strain associated with prolonged near-focus. 🔹 Support eye health with leafy greens, berries, omega-3-rich foods, movement, and time outdoors. 🔹 Comprehensive eye examinations and technologies such as OCT may reveal important information that extends far beyond eyesight. 👩‍⚕️ Guest Biography Dr. Meenal Agarwal is a board-certified optometrist and spatial awareness expert who takes a holistic approach to vision as a gateway to brain health, focus, and overall well-being. She integrates optometry, neuroscience, and lifestyle medicine to explore the root causes of visual problems and their potential impact on cognition, neurodegeneration, and everyday performance. A vocal advocate for reducing digital overload, Dr. Agarwal helps people restore sharper focus, balance, spatial awareness, and presence in an increasingly screen-driven world. Dr. Agarwal owns three thriving practices in the Greater Toronto Area and specializes in dry eye therapy, myopia control, and laser vision correction. She is also the host of Uncover Your Eyes: The Truth About Health & Wellness, and her insights have been featured in TIME, Forbes, and Fox News. Her upcoming book, Stuck in a Flat World, explores how modern visual habits affect the brain and what we can do to reclaim healthier vision and spatial awareness. 🌐 https://www.drmeenal.com/  📸 https://www.instagram.com/dr.meenalagarwal/  🔵 https://www.facebook.com/meenalagarwaldr  💬 https://www.threads.com/@dr.meenalagarwal

    333: Resiliency Radio with Dr. Jill: Vision as a Gateway: How to Optimize Focus & Resilience with Dr. Meenal Agarwal

  2. 7h ago

    Resiliency Radio with Dr. Jill: Childhood Immunity & Lifelong Health with Dr. Somer DelSignore

    In this episode of Resiliency Radio with Dr. Jill, Dr. Jill Carnahan welcomes pediatric integrative medicine expert Dr. Somer DelSignore to explore why childhood immune health may have profound implications for lifelong health and disease risk. As chronic illness, immune dysfunction, behavioral challenges, and neurodevelopmental conditions become increasingly complex in children, Dr. DelSignore explains why symptoms shouldn't always be viewed in isolation. Instead, she investigates the interconnected roles of inflammation, infections, gut health, environmental toxins, nutrition, genetics, and immune regulation. Together, they explore her R.E.S.E.T. Protocol, the potential biomedical drivers behind conditions such as ADHD and PANS/PANDAS, the importance of investigating mold and vector-borne infections, and practical ways parents can help build greater immune resilience in their children. 🔑 5 Key Discussions ① 🛡️ Why Childhood Immune Resilience Matters ⇨ Dr. DelSignore describes seeing increasingly complex chronic conditions in children whose immune systems appear to remain in a persistent state of dysregulation. ⇨ Modern environmental exposures, processed foods, infections, stressors, and lifestyle changes may interact with individual biology and influence long-term health. ② 🔄 The R.E.S.E.T. Protocol & Root-Cause Medicine ⇨ Dr. DelSignore uses her R.E.S.E.T. framework: Reduce Inflammation, Eliminate Toxins, Support Gut Health, Eradicate Infection, Transform Health. ⇨ Rather than treating each symptom independently, the approach looks for connections between immune function, neurological health, gastrointestinal health, infections, and environmental exposures. ③ 🧠 ADHD, PANS/PANDAS & the Brain-Immune Connection ⇨ Behavioral and neuropsychiatric symptoms may sometimes have underlying biomedical contributors that deserve investigation. ⇨ Dr. DelSignore discusses the potential roles of inflammation, infections, toxins, and immune activation in children presenting with ADHD, anxiety, depression, PANS/PANDAS, and other complex symptoms. ④ 🦠 Infections, Mold & Environmental Exposures ⇨ Her evaluation considers mold, heavy metals, VOCs, plastics, and other potential environmental exposures alongside a child's medical history. ⇨ She also investigates infections including Strep, EBV, HHV-6, Borrelia, Babesia, and Bartonella when clinically relevant to a child's presentation. ⑤ 🌱 Building Healthier, More Resilient Kids ⇨ Whole foods, gut health, thoughtful supplementation, reducing unnecessary exposures, and appropriate testing can all form part of an individualized approach. ⇨ Free play, outdoor activity, exploration, and meaningful human connection are also important components of healthy neurological and immune development. ⭐ Key Takeaways 🔹 Childhood symptoms should be considered within the context of the whole child rather than as isolated diagnoses. 🔹 Immune dysfunction and chronic inflammation may contribute to both physical and neurological symptoms. 🔹 Gut health is closely connected to immune regulation and systemic inflammation. 🔹 Mold, environmental toxins, and chronic infections may be important factors to investigate in complex pediatric illness. 🔹 Conditions such as PANS/PANDAS highlight the important relationship between infection, immunity, and the brain. 🔹 Diet changes are often most sustainable when introduced gradually, especially with picky eaters. 🔹 Root-cause medicine seeks to understand why symptoms are occurring rather than focusing solely on suppressing them. 🔹 Supporting immune resilience early in life may help create a stronger foundation for lifelong health. 👩‍⚕️ Guest Biography Dr. Somer DelSignore is a pediatric board-certified provider, Fellow at MAPS and AAOT, and a member of ILADS and SSRP. Inspired to combine the depth of integrative care with the precision of medical science, she created the R.E.S.E.T. Protocol to address the root causes of pediatric and congenital illness. Her graduate and doctorate studies at PENN and SUNY Upstate Medical University, combined with integrative medicine internships with world-renowned experts, have helped establish her expertise in developing precision-based treatment plans for children with neuro-immune conditions, chronic illness, and congenital vector-borne diseases. Dr. DelSignore is the Founder and CEO of Hudson Valley Integrative Health and Wholesome Root Nutraceuticals in Beacon, New York, where her work focuses on identifying the complex factors contributing to pediatric illness and helping children build greater health and resilience. 🌐 Website: https://www.hudsonvalleyintegrativehealth.com/  📸 Instagram: https://www.instagram.com/nylymesandpans/  💼 LinkedIn: https://www.linkedin.com/in/somerdelsignorekidslyme/  🔵 Facebook: https://www.facebook.com/nylymesandpans/

    Resiliency Radio with Dr. Jill: Childhood Immunity & Lifelong Health with Dr. Somer DelSignore

  3. Sep 2

    Resiliency Radio with Dr. Jill: Infections & the Brain: The Overlooked Drivers of Chronic Inflammation with Nikki Schultek

    In this episode of Resiliency Radio with Dr. Jill, Dr. Jill Carnahan sits down with researcher and collaboration architect Nikki Schultek to explore an often-overlooked contributor to chronic disease: persistent infections and their impact on inflammation, immunity, and the brain. Drawing from her own experience with severe chronic illness, Lyme disease, Chlamydia pneumoniae, and autoimmunity, Nikki shares how her personal health journey led her into research and a mission to connect scientific disciplines that too often operate in isolation. Together, they explore the emerging concept of the pathobiome, the potential infectious drivers of Alzheimer's and other neurodegenerative diseases, the challenges of diagnosing persistent infections, and why understanding the body as an interconnected ecosystem could transform the future of chronic illness research and treatment. 🔑 5 Key Discussions ① 🦠 Chronic Infections as Hidden Drivers of Disease ⇨ Persistent infections may play an overlooked role in autoimmune disease, chronic fatigue, asthma, neurological illness, and other complex chronic conditions. ⇨ Pathogens including Lyme-associated organisms, Chlamydia pneumoniae, Mycoplasma, Epstein-Barr virus, Bartonella, and Babesia may persist or reactivate under certain conditions rather than behaving solely as short-lived infections. ② 🧠 The Brain Is Part of a Larger Ecosystem ⇨ Brain health cannot be separated from immune function, systemic inflammation, the gut, environmental exposures, and infectious burden. ⇨ Emerging research challenges the traditional view of the brain as an isolated, sterile environment and raises important questions about microbes, immune activity, and chronic neuroinflammation. ③ 🔬 Rethinking Alzheimer's & Neurodegeneration ⇨ Researchers are investigating whether infections and immune responses may contribute to diseases such as Alzheimer's and Multiple Sclerosis. ⇨ The Alzheimer's Pathobiome Initiative is bringing researchers together to investigate whether amyloid plaques, tau changes, and other features of neurodegeneration may be connected to microbial activity and the body's response to infection. ④ 🧬 Understanding the Pathobiome ⇨ The pathobiome expands beyond simply identifying which microorganisms are present—it considers the relationship between microbes, the host immune system, hormones, environmental exposures, and the body's overall terrain. ⇨ Disease may emerge when changes in this ecosystem allow normally controlled or latent organisms to proliferate, reactivate, or provoke damaging immune responses. ⑤ 🤝 Building a New Model for Chronic Illness Research ⇨ Complex illnesses rarely fit neatly into one medical specialty, making collaboration between immunologists, neurologists, infectious disease researchers, clinicians, and other experts essential. ⇨ Nikki's work as a collaboration architect focuses on breaking down scientific silos and accelerating the translation of emerging research into meaningful clinical understanding. ⭐ Key Takeaways 🔹 Chronic infections may be important but frequently overlooked contributors to complex chronic illness. 🔹 Brain inflammation can be influenced by immune dysfunction and processes occurring throughout the body. 🔹 Chlamydia pneumoniae and other atypical pathogens deserve greater attention when investigating persistent illness. 🔹 Current testing may not always clearly distinguish between historical exposure and clinically relevant persistent infection. 🔹 COVID-19 may disrupt immune function and potentially contribute to the reactivation of latent infections. 🔹 The pathobiome provides a broader framework for understanding interactions between microbes, immunity, environment, and disease. 🔹 Infectious and immune mechanisms are increasingly being investigated in Alzheimer's and other neurodegenerative conditions. 🔹 Collaboration across scientific disciplines will be critical for advancing research into complex chronic disease. 👩‍🔬 Guest Biography Nikki Schultek is the Executive Director of the Alzheimer's Pathobiome Initiative (AlzPI), Principal Founder of Intracell Research Group, LLC, and Founding Director of the Pathobiome Research Center at the Philadelphia College of Osteopathic Medicine (PCOM). After earning a BS in Business Administration from Villanova University, Nikki began her career with Pfizer and Genentech. Her professional direction changed following her own recovery from Lyme disease and other chronic infections, inspiring her to focus on advancing research into infection-associated chronic illnesses, including Alzheimer's disease, PANDAS/PANS, and asthma. Since founding Intracell Research Group in 2017, Nikki has built global collaborations connecting researchers, clinicians, academic institutions, and other stakeholders. She is also a co-investigator on the 3,200-patient iTREAT-PC asthma clinical trial and serves on the Board of Directors of the International Lyme and Associated Diseases Education Foundation. Nikki has helped secure philanthropic funding to launch AlzPI research across eight academic centers and co-led the development of a research roadmap published in Alzheimer's & Dementia in 2023. Her work is helping advance rigorous investigation into the potential role of microbial infections in Alzheimer's disease, dementia, and other brain disorders. 🌐 Connect & Learn More 🔗 Alzheimer's Pathobiome Initiative: https://www.alzpi.org/  🔗 Intracell Research Group: https://www.intracellresearchgroup.com/  🔗 Pathobiome Research Center at PCOM: https://www.pcom.edu/research/pbrc/  🔬 Current Mission The global consortium is working to secure funding to fully operationalize its international research collaboration and accelerate investigation into the role infections may play in Alzheimer's disease and other brain diseases.

    Resiliency Radio with Dr. Jill: Infections & the Brain: The Overlooked Drivers of Chronic Inflammation with Nikki Schultek

  4. Aug 26

    Resiliency Radio with Dr. Jill: Immune Resilience: The Future of Longevity with Dr. Isaac Melamed

    In this episode of Resiliency Radio with Dr. Jill, Dr. Jill Carnahan welcomes renowned immunologist Dr. Isaac Melamed for a fascinating exploration of the immune system and its powerful influence on whole-body health, resilience, and longevity. Dr. Melamed explains why the immune system is far more than our defense against infections. Its intricate connections with the brain, nervous system, mitochondria, environment, and even our emotional experiences may help explain everything from autoimmunity and chronic pain to cognitive decline, Long COVID, allergies, and cancer. Together, they explore the emerging science of neuroimmunology, immune aging, IVIG, epigenetics, and a new vision for proactive "Immuno Wellness" focused on identifying dysfunction before it progresses into disease. 🔑 5 Key Discussions ① 🧠 The Neuroimmune Connection ⇨ The nervous and immune systems constantly communicate, creating a powerful connection between immune function and brain health. ⇨ Infections and immune activation may contribute to neurological, psychiatric, and cognitive symptoms, including those seen with Long COVID. ② 🛡️ Immune Dysfunction & Chronic Disease ⇨ Immune dysfunction extends far beyond traditional autoimmune disease and can influence infections, chronic pain, cognitive decline, allergies, and cancer. ⇨ Conditions such as Common Variable Immune Deficiency (CVID) may present in diverse and unexpected ways, making deeper immune evaluation important. ③ 💉 IVIG & Immune Modulation ⇨ Intravenous Immunoglobulin (IVIG) can both replace missing antibodies and help modulate abnormal immune responses. ⇨ Its use in conditions such as Kawasaki disease and Guillain-Barré syndrome demonstrates the therapeutic potential of influencing the immune system even when every underlying mechanism isn't fully understood. ④ 🧬 Stress, Environment & Epigenetics ⇨ Genetics aren't the entire story. Stress, nutrition, infections, environmental exposures, and lifestyle can influence gene expression and immune behavior. ⇨ Childhood stress and other environmental triggers may contribute to persistent immune activation and potentially increase susceptibility to autoimmune disease later in life. ⑤ 🔬 The Future of Immune Resilience & Longevity ⇨ Emerging research is expanding beyond B and T cells to investigate mast cells, complement, innate immunity, mitochondria, biologics, immunotherapy, and immune aging. ⇨ Dr. Melamed's concept of Immuno Wellness shifts the focus toward prevention—understanding immune health early rather than waiting until significant disease develops. ⭐ Key Takeaways 🔹 The immune system is deeply interconnected with the brain and nervous system. 🔹 Chronic illness may involve multiple interacting components of immunity rather than one isolated abnormality. 🔹 Immune deficiencies can present differently between patients and throughout a person's lifetime. 🔹 IVIG can provide both immune replacement and immune-modulating effects. 🔹 Stress, infections, nutrition, lifestyle, and environmental exposures can influence immune function through epigenetic mechanisms. 🔹 Immune aging may contribute to declining immune memory and resilience as we get older. 🔹 Listening carefully to patients—and taking unexplained symptoms seriously—is essential when investigating complex immune disorders. 🔹 The future of longevity may include proactively measuring and supporting immune resilience before disease develops. 👨‍⚕️ Guest Biography Dr. Isaac Melamed is a nationally recognized immunologist, physician, and researcher with more than 35 years of clinical experience and over two decades dedicated to advancing the understanding of immune-related diseases. As the founder of Veros Health, Dr. Melamed is known for his pioneering work in primary and secondary immune deficiencies and for exploring the critical relationship between the immune system and nervous system. He has authored more than 100 scientific publications, lectured internationally, and received numerous honors for his contributions to clinical immunology. Through his innovative, patient-centered approach, Dr. Melamed is committed to identifying immune dysfunction early, investigating the underlying drivers of disease, and developing proactive strategies that help patients achieve greater health, resilience, and longevity. https://www.drmeenal.com/  https://www.facebook.com/meenalagarwaldr?mibextid=LQQJ4d  https://www.instagram.com/dr.meenalagarwal/?hl=en  https://www.threads.com/@dr.meenalagarwal

    Resiliency Radio with Dr. Jill: Immune Resilience: The Future of Longevity with Dr. Isaac Melamed

  5. Aug 19

    Resiliency Radio with Dr. Jill: Perimenopause: The Silent Fertility Disrupter with Dr. Jaime Knopman

    In this episode of Resiliency Radio with Dr. Jill, Dr. Jill Carnahan welcomes reproductive endocrinologist and fertility specialist Dr. Jaime Knopman to explore the often-overlooked connection between perimenopause, fertility decline, and reproductive health. With infertility now affecting an estimated one in six people worldwide, Dr. Knopman explains why fertility should be treated as an essential marker of women's health—not a conversation that begins only when someone is ready to become pregnant. Together, they discuss ovarian reserve, AMH testing, egg freezing, delayed motherhood, fertility after cancer treatment, and what women need to understand about their reproductive timeline. Whether you're planning a family now, considering pregnancy later, or entering perimenopause, this conversation provides practical insights to help you make informed decisions about fertility and your future. 🔑 5 Key Discussions ① 🧬 Perimenopause & the Fertility Window ⇨ Fertility naturally declines with age, even while menstrual cycles and ovulation may continue during perimenopause. ⇨ Understanding your reproductive timeline earlier gives you more options for future family planning. ② 🥚 Egg Freezing & Fertility Preservation ⇨ Egg freezing can provide an important option for women delaying pregnancy or facing treatments that may affect fertility. ⇨ Fertility preservation is increasingly becoming part of proactive reproductive healthcare rather than something considered only after a medical diagnosis. ③ 🧪 Understanding AMH & Ovarian Reserve ⇨ AMH blood testing and antral follicle counts can help estimate the quantity of eggs remaining in the ovaries. ⇨ Ovarian reserve reflects egg quantity—not egg quality—and results must always be interpreted alongside age and medical history. ④ 🌿 What Really Influences Fertility? ⇨ Age remains one of the most important factors, but metabolic health, sleep, smoking, genetics, diet, and environmental exposures may also influence reproductive health. ⇨ Severe menstrual symptoms should never simply be dismissed, as they may signal underlying conditions affecting fertility. ⑤ 🔬 The Future of Fertility Medicine ⇨ Artificial intelligence and advances in embryo genetic screening are helping fertility specialists improve treatment selection and outcomes. ⇨ Better testing, earlier education, and personalized fertility planning are giving women greater reproductive autonomy. ⭐ Key Takeaways 🔹 Fertility should be considered an important marker of women's overall health. 🔹 Perimenopause does not mean pregnancy is impossible. 🔹 Age remains one of the most significant factors affecting egg quality and fertility. 🔹 AMH measures ovarian reserve but does not independently predict whether a woman can become pregnant. 🔹 Fertility preservation can provide women with more options when delaying parenthood. 🔹 Earlier education allows women to make more informed decisions about their reproductive future. 👩‍⚕️ Guest Biography Dr. Jaime Knopman is a double board-certified reproductive endocrinologist and infertility specialist and serves as Director of Fertility Preservation at CCRM Fertility of New York. A graduate of the University of Pennsylvania and the Icahn School of Medicine at Mount Sinai, Dr. Knopman completed her residency and fellowship training at NYU Medical Center. She is nationally recognized for her expertise in reproductive endocrinology, IVF, egg freezing, fertility preservation, and reproductive care for patients facing cancer treatment. Dr. Knopman has authored landmark research on fertility preservation for cancer patients and has been consistently recognized as a New York Super Doctor, Castle Connolly Top Doctor, and New York Magazine Top Doctor. She also serves as Medical Director of Chick Mission and on the advisory boards of CoFertility and The Breasties, helping expand fertility education, advocacy, and access to reproductive care. 🌐 Website: https://drjaimeknopman.com/  📸 Instagram: https://www.instagram.com/drjaimeknopman/

    Resiliency Radio with Dr. Jill: Perimenopause: The Silent Fertility Disrupter with Dr. Jaime Knopman

  6. Aug 12

    Resiliency Radio with Dr. Jill: The Hidden Drivers of Brain Diseases with Dr. David Perlmutter

    In this episode of Resiliency Radio with Dr. Jill, Dr. Jill Carnahan welcomes renowned neurologist and bestselling author Dr. David Perlmutter to explore the emerging science behind brain health, neuroinflammation, and cognitive resilience. Drawing from his groundbreaking new book, Brain Defenders, Dr. Perlmutter explains how microglia—the brain's immune cells—play a central role in protecting or damaging the brain depending on our metabolism, lifestyle, and environment. Together they discuss why Alzheimer's and Parkinson's disease begin decades before symptoms appear, why inflammation and insulin resistance are major drivers of neurodegeneration, and what we can do today to protect lifelong brain health. Whether you're concerned about memory loss, dementia prevention, or optimizing cognitive performance, this episode offers science-backed strategies to build a healthier, more resilient brain. 🔑 5 Key Discussions ① 🧠 Microglia: The Brain's Defenders ⇨ Microglia protect neurons, maintain synapses, and defend the brain from injury and infection. ⇨ Chronic inflammation can transform these protective cells into drivers of Alzheimer's, Parkinson's, and cognitive decline. ② 🔥 Immunometabolism & Brain Health ⇨ Blood sugar, insulin resistance, inflammation, and metabolism directly influence how microglia function. ⇨ Improving metabolic health helps create a brain environment that supports healing rather than degeneration. ③ 🥗 Lifestyle Shapes Brain Destiny ⇨ Nutrition, exercise, sleep, stress management, and social connection have profound effects on brain health. ⇨ Healthy daily habits can dramatically reduce the risk of neurodegenerative disease—even with genetic risk factors like APOE4. ④ ⚠️ Looking Beyond Amyloid ⇨ Current Alzheimer's treatments targeting amyloid offer limited benefit while failing to address upstream causes. ⇨ Prevention begins by reducing inflammation, supporting metabolism, and protecting brain immunity years before symptoms develop. ⑤ 🌱 Protecting the Aging Brain ⇨ Key strategies include optimizing vitamin D, omega-3 fatty acids, B vitamins, blood sugar, exercise, and toxin reduction. ⇨ Supporting microglial health may become one of the most important approaches to lifelong cognitive resilience. ⭐ Key Takeaways 🔹 Brain health begins with metabolic and immune health. 🔹 Chronic inflammation is a major driver of cognitive decline. 🔹 Microglia can either protect or damage the brain depending on lifestyle factors. 🔹 Exercise, nutrition, sleep, and social connection support lifelong brain resilience. 🔹 Prevention offers the greatest opportunity to reduce Alzheimer's and Parkinson's risk. 👨‍⚕️ Guest Biography Dr. David Perlmutter is a board-certified neurologist, Fellow of the American College of Nutrition, and six-time New York Times bestselling author specializing in the intersection of neurology, nutrition, and brain health. His internationally acclaimed books—including Grain Brain—have been published in more than 30 languages and have transformed how millions understand the connection between lifestyle, metabolism, and cognitive health. Dr. Perlmutter serves on the Editorial Board of the Journal of Alzheimer's Disease and lectures worldwide on neurodegeneration, inflammation, nutrition, and longevity. His newest book, Brain Defenders, explores the vital role of microglia—the brain's immune cells—in protecting, repairing, and reprogramming the brain for lifelong cognitive resilience. 🌐 Website: https://drperlmutter.com/  📘 Brain Defenders: http://braindefenders.com/  📸 Instagram: https://www.instagram.com/davidperlmutter/  ▶️ YouTube: https://www.youtube.com/user/DavidPerlmutterMD  𝕏 X: https://x.com/davidperlmutter

    Resiliency Radio with Dr. Jill: The Hidden Drivers of Brain Diseases with Dr. David Perlmutter

  7. Aug 5

    Resiliency Radio with Dr. Jill - The New Science of Weight loss, Longevity and Behavioral Change with Dr. John Oberg

    In this episode of Resiliency Radio with Dr. Jill, Dr. Jill Carnahan welcomes Dr. John Oberg, healthcare innovator, behavioral scientist, and founder of Precina Health, to explore why lasting health transformation begins with behavior—not willpower. Together they discuss the science behind sustainable weight loss, GLP-1 medications, Type 2 diabetes reversal, and longevity through the lens of human behavior. Dr. Oberg explains how his groundbreaking START Model combines behavioral science with personalized medical care to help patients create lasting lifestyle changes that improve both lifespan and health span. Whether you're struggling with weight, chronic disease, or simply looking to build healthier habits, this episode provides practical insights into creating meaningful, lifelong change. 🔑 5 Key Discussions ① 🧠 The Science of Behavioral Change ⇨ Sustainable health improvements come from understanding human behavior rather than relying solely on willpower. ⇨ Small, personalized habit changes create lasting transformations over time. ② ⚖️ Weight Loss Beyond the Scale ⇨ GLP-1 medications can accelerate progress, but they work best alongside healthy nutrition, movement, and behavioral support. ⇨ Long-term success depends on building sustainable habits rather than lifelong dependence on medication. ③ 🩺 Transforming Chronic Disease ⇨ The START Model helps patients improve Type 2 diabetes, metabolic health, and overall wellness through personalized care. ⇨ Treating the whole person—not just symptoms—leads to better long-term outcomes. ④ ❤️ Finding Your "Why" ⇨ A meaningful personal purpose is one of the strongest predictors of successful lifestyle change. ⇨ Connecting daily habits to long-term goals creates lasting motivation for better health. ⑤ 🌱 Longevity Through Human Connection ⇨ Health span depends on more than diet and exercise—it also requires meaningful relationships and emotional well-being. ⇨ Technology and AI should support healthcare while strengthening, not replacing, authentic human connection. ⭐ Key Takeaways 🔹 Lasting weight loss begins with behavior change, not willpower. 🔹 GLP-1 medications are tools—not complete solutions—for long-term health. 🔹 Small, consistent habits produce sustainable results. 🔹 Human connection plays a vital role in longevity and well-being. 🔹 Improving health span is just as important as extending lifespan. 👨‍⚕️ Guest Biography Dr. John Oberg is an entrepreneur, healthcare innovator, executive advisor, professor, and behavioral scientist with more than three decades of experience helping organizations and individuals navigate growth, change, and human performance. He is the founder of pioneering healthcare companies including Precina Health and Sedera, where he has helped develop innovative approaches to chronic disease management by combining behavioral science, personalized medicine, and technology. Holding a doctorate from the University of Southern California and an MBA from the University of New Mexico, Dr. Oberg specializes in creating high-performing healthcare systems that improve both patient outcomes and clinician well-being. His mission is to help people thrive by strengthening the connection between purpose, performance, and lasting behavioral change. 🌐 Website: https://johnoberg.com/  🏥 Precina Health: https://precina.com/

    Resiliency Radio with Dr. Jill - The New Science of Weight loss, Longevity and Behavioral Change with Dr. John Oberg

  8. Jul 29

    Resiliency Radio with Dr. Jill: The Future of Personalized Hormone Therapy with Dr. Nayan Patel

    🎁 Special Offer: Use code DRJILL for discounts at Auro Wellness. https://aurowellness.com/drjill In this episode of Resiliency Radio with Dr. Jill, Dr. Jill Carnahan sits down with Dr. Nayan Patel, renowned longevity pharmacist and author of The Glutathione Revolution, to explore the future of personalized hormone therapy, glutathione optimization, and healthy aging. Together they discuss why hormone therapy is about far more than replacing hormones—it requires supporting detoxification, reducing inflammation, and optimizing the body's natural healing systems. Dr. Patel explains the critical role of glutathione, the body's master antioxidant, and shares practical strategies for improving energy, metabolism, hormone balance, and longevity through a personalized, root-cause approach. Whether you're navigating menopause, andropause, hormone replacement therapy, or simply looking to age well, this episode offers science-backed insights into building resilience from the inside out. 🔑 5 Key Discussions ① 🧬 The Future of Personalized Hormone Therapy ⇨ Hormone optimization begins with understanding the body's unique biology—not one-size-fits-all protocols. ⇨ Successful hormone therapy depends on balancing stress, metabolism, detoxification, and hormone signaling. ② ✨ Glutathione: The Master Antioxidant ⇨ Glutathione protects cells from oxidative stress while supporting detoxification and healthy aging. ⇨ Environmental toxins, alcohol, poor diet, and chronic stress can rapidly deplete glutathione reserves. ③ ⚖️ The Hormone Hierarchy ⇨ Cortisol, insulin, thyroid hormones, and sex hormones work together as an interconnected system. ⇨ Addressing stress and metabolic health first creates the foundation for safe and effective hormone balance. ④ 🔬 Detoxification & Longevity ⇨ Efficient hormone metabolism requires healthy detoxification pathways. ⇨ Supporting glutathione production allows the body to safely process hormones and environmental toxins. ⑤ 🚀 Building a Longer, Healthier Life ⇨ Longevity is driven by improving cellular communication, reducing inflammation, and supporting the body's natural ability to heal. ⇨ Personalized testing and root-cause medicine create better long-term health outcomes than symptom management alone. ⭐ Key Takeaways 🔹 Glutathione is essential for detoxification, cellular protection, and healthy aging. 🔹 Hormone therapy works best when stress, metabolism, and detoxification are optimized first. 🔹 Personalized medicine offers safer and more effective hormone replacement strategies. 🔹 Reducing toxic exposure supports hormone balance and longevity. 🔹 Healthy aging begins by addressing root causes—not simply replacing hormones. 👨‍⚕️ Guest Biography Dr. Nayan Patel is an internationally recognized longevity pharmacist, wellness expert, educator, and author of the bestselling book The Glutathione Revolution. Since 1999, he has partnered with physicians to develop personalized medication and nutrition protocols that optimize health, hormone balance, and longevity. Following more than a decade of clinical research, Dr. Patel developed a patented topical glutathione delivery technology, transforming how this critical antioxidant is absorbed and utilized by the body. His work has helped physicians, executives, athletes, and celebrities better understand the role of glutathione in detoxification, energy production, healthy aging, and disease prevention. 🌐 Website: https://aurowellness.com/drjill  📚 Featured Book: The Glutathione Revolution: Fight Disease, Slow Aging & Increase Energy 🎁 Special Offer: Use code DRJILL for discounts at Auro Wellness. https://aurowellness.com/drjill

    Resiliency Radio with Dr. Jill: The Future of Personalized Hormone Therapy with Dr. Nayan Patel
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Dr. Jill Carnahan, MD, ABIHM, ABoIM, IFMCP is a globally recognized leader in functional and integrative medicine, specializing in complex chronic illness, environmental toxicity, immune dysfunction, and resilience-based healing. She is dually board-certified and the founder and Medical Director of Flatiron Functional Medicine in Colorado, where she practices personalized precision medicine using advanced diagnostics and systems-based, root-cause care. A survivor of breast cancer, Crohn's disease, and severe mold-related illness, Dr. Jill brings both scientific expertise and lived experience to her work—bridging cutting-edge medical research with compassionate, patient-centered care. Her clinical approach focuses on restoring physiological resilience, optimizing immune and metabolic function, and supporting long-term health through individualized, evidence-informed protocols. Dr. Jill is the best-selling author of Unexpected: Finding Resilience Through Functional Medicine, Science, and Faith and the executive producer and featured physician in the award-winning documentary Doctor/Patient, which explores the future of medicine through the lens of healing, personalization, and human connection. As host of Resiliency Radio, Dr. Jill engages leading experts in functional medicine, longevity science, neuroscience, nutrition, environmental health, spirituality, and human performance. Each episode translates complex research into practical insights to help listeners build resilience, improve healthspan, and thrive in the face of modern health challenges. A sought-after international speaker, educator, and mentor, Dr. Jill is known for making advanced medical science accessible, hopeful, and actionable—delivered with clarity, compassion, and authenticity. Follow @drjillcarnahan for podcasts, research-backed education, articles, and resources. Disclaimer: This podcast is for educational purposes only and does not provide individual medical advice. Please consult your healthcare provider for personal medical care.

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