First Principles

Adrian Wells
  • 5.0 (1)
  • BUSINESS
  • UPDATED DAILY

First Principles isn't another business podcast recycling the same startup stories. Adrian Wells takes the fundamentals that actually matter and breaks them down like you're having coffee with the smartest professor you ever had. Wells spent twelve years teaching philosophy and critical thinking before ditching the lecture hall for the microphone. Turns out, the same principles that help you think clearly about ancient Greek ethics also work pretty well for modern business decisions. Who knew? Every episode strips away the latest trends and buzzwords to focus on the core ideas that don't change. How to actually evaluate evidence when everyone's throwing around statistics. Why most "revolutionary" business advice is just old wine in new bottles. The thinking patterns that separate smart decisions from lucky guesses. You won't get hyped-up success stories or flavor-of-the-month strategies. Instead, you'll learn how to think through problems the way philosophers have for centuries, applied to the stuff that matters in your work and life right now. Multiple new episodes drop daily, so there's always something fresh when you need it. Follow now if you're ready to think better, not just think faster. Multiple new episodes daily—follow now!

  1. 9H AGO

    Wim Hof: The $47M Disease Industry Doesn't Want You Knowing This

    What if everything you've been told about fighting disease and inflammation is keeping you sick? Adrian Wells breaks down how Wim Hof's controversial methods might actually work through measurable biological mechanisms that the medical establishment is just starting to understand. 🎯 What You'll Learn: • How Hof's trained participants showed 50% less inflammatory response when injected with bacterial endotoxin in a controlled study • Why brain imaging reveals his breathing method activates the periaqueductal gray area that controls pain and stress responses • The science behind 530% increases in noradrenaline levels and how cold exposure can boost metabolism by 15% 👤 Perfect for: lifelong learners and anyone passionate about personal growth who wants to understand what science actually says about immune function and inflammation control. 📍 Chapters: [00:00] Adrian Wells introduces the $47M question about disease treatment [01:30] The 2014 endotoxin study that shocked researchers [04:00] Brain imaging reveals how breathing changes neural pathways [07:00] Noradrenaline spikes and what they mean for your immune system [10:00] Cold exposure science: brown fat activation and metabolic benefits [12:00] Practical takeaways you can test yourself The implications are pretty wild. If controlled breathing and cold exposure can measurably influence immune response, why isn't this being studied more aggressively? Wells walks through the actual research without the hype, showing you what the data really says about inflammation, stress response, and immune function. 🔔 Never miss an episode: Follow First Principles on Spotify or Apple Podcasts and turn on notifications. New episodes drop daily, your next favorite insight is one tap away. 🔍 Topics: Wim Hof method, inflammation research, immune system, cold exposure therapy, breathing techniques Find all episodes at First Principles ------------- Keywords: logical reasoning, wealth mindset, thinking skills, social media addiction, depression stories, performance optimization Learn more about your ad choices. Visit megaphone.fm/adchoices

    27 min

  2. 21H AGO

    Dr. Mindy Pelz: What Ozempic Actually Does To Your Body (The Truth)

    Why would a 63-year-old naturally produce the same weight-loss hormone as someone on Ozempic? Dr. Mindy Pelz reveals what pharmaceutical companies aren't telling you about GLP-1, plus the three foods hiding in your kitchen that might be setting you up for cancer. Adrian Wells breaks down the science behind fasting, metabolic health, and why your body already has everything it needs to regulate weight naturally. 🎯 What You'll Learn: • Why Ozempic works by mimicking a hormone your body used to make abundantly • The 3 specific foods making up 60% of American diets that increase cancer risk • How intermittent fasting can boost your natural GLP-1 production without injections • Which seed oils and additives Dr. Pelz says to avoid immediately 👤 Perfect for: lifelong learners and anyone questioning what's really in their food and wondering if there's a natural alternative to weight loss drugs. 📍 Chapters: [00:00] Adrian introduces Dr. Pelz and the Ozempic truth [01:30] What GLP-1 actually does in your body [03:45] Why we stop producing this hormone as we age [06:00] The three cancer-linked foods in your pantry [08:30] How fasting triggers natural GLP-1 production [10:15] Seed oils, sugar, and artificial additives breakdown [11:30] Practical steps you can take today 🔔 Never miss an episode: Follow First Principles on Spotify and Apple Podcasts for your daily dose of clear thinking. New episodes drop daily, so your next breakthrough insight is just one tap away. 🔍 Topics: ozempic, intermittent fasting, GLP-1 hormone, cancer prevention, seed oils Find all episodes at First Principles -------- Keywords: health myths, cognitive biases, social media addiction, anxiety management, entrepreneurship philosophy, ai dangers, decision making Learn more about your ad choices. Visit megaphone.fm/adchoices

    21 min

  3. 1D AGO

    The Sleep Scientist Who Makes Insomniacs Stay Awake (Then Cures Them)

    What if the cure for insomnia involves staying awake even longer? Adrian Wells explores the counterintuitive world of sleep restriction therapy, where scientists deliberately make chronic insomniacs spend less time in bed to fix their broken sleep patterns. It sounds brutal, but the results speak for themselves. 🎯 What You'll Learn: • Why sleep restriction therapy has a 70-80% success rate for chronic insomnia (better than most medications) • How your brain clears toxins 60% faster during deep sleep using a newly discovered system called the glymphatic network • The adenosine buildup trick that explains why you feel tired and how insomniacs accidentally train their brains to stay alert in bed • Why spending 9-10 hours in bed but only sleeping 5-6 hours creates a vicious cycle that keeps you awake 👤 Perfect for: lifelong learners and anyone who's ever stared at the ceiling wondering why their brain won't shut off, plus anyone curious about how extreme scientific methods sometimes work better than gentle approaches. 📍 Chapters: [00:00] Adrian Wells introduces the sleep scientist's painful paradox [01:45] Sleep restriction therapy: making insomnia worse to make it better [04:15] The glymphatic system: your brain's nighttime cleaning crew [07:30] Adenosine buildup and why tired doesn't always mean sleepy [09:45] Sleep efficiency: the 85% rule that changes everything [11:30] Key takeaways you can use tonight (carefully) 🔔 Never miss an episode: Follow First Principles on your podcast app and turn on notifications. New episodes drop daily, your next favorite insight is one tap away. 🔍 Topics: sleep science, insomnia treatment, sleep restriction therapy, glymphatic system, adenosine buildup Find all episodes at First Principles -------------- Keywords: anxiety management, business strategy, relationship psychology Learn more about your ad choices. Visit megaphone.fm/adchoices

    33 min

  4. 1D AGO

    What Ozempic Really Does To Your Gut (It's Not What You Think)

    What if the weight loss drug everyone's talking about is quietly rewiring your gut in ways doctors barely understand? Adrian Wells breaks down the shocking research on Ozempic's hidden effects on your microbiome, and why hospitals are seeing a 40% spike in severe side effects. 🎯 What You'll Learn: • How Ozempic boosts beneficial gut bacteria by up to 300% (and what that actually means for your health) • Why 70% of users completely change their food preferences, not just their appetite • The dosing mistakes sending people to emergency rooms at record rates • Why your gut changes stick around for months after you stop taking the drug 👤 Perfect for: lifelong learners and anyone passionate about personal growth who wants to understand what's really happening inside their body when they hear about these "miracle" drugs. 📍 Chapters: [00:00] Adrian Wells introduces Ozempic's microbiome mystery [01:45] The gut bacteria explosion no one saw coming [04:20] Food preferences vs. appetite: what's really changing [06:50] Emergency room crisis: when "more is better" goes wrong [09:30] The persistence effect: why changes outlast the drug [11:40] What this means for your health decisions The research is pretty wild. Turns out Ozempic doesn't just suppress appetite through brain signals. It's literally changing which bacteria live in your gut, and those bacteria are talking back to your brain in ways we're just starting to figure out. But here's the concerning part: doctors are prescribing doses based on old assumptions, and patients are paying the price. 🔔 Never miss an episode: Follow First Principles on Apple Podcasts or Spotify and turn on notifications. New episodes drop daily, your next favorite insight is one tap away. 🔍 Topics: Ozempic side effects, gut microbiome, GLP-1 drugs, medication dosing, digestive health Find all episodes at First Principles --- Keywords: business fundamentals, relationship psychology, behavioral economics Learn more about your ad choices. Visit megaphone.fm/adchoices

    26 min

  5. 2D AGO

    Gender Expert: Men Are Emotionally Dependent On Women (Not The Other Way Around)

    What if everything you think you know about men and emotions is backwards? Adrian Wells explores groundbreaking research suggesting men aren't emotionally distant by nature. They're actually more emotionally dependent on women than we realize, and our current approach to helping them might be making things worse. 🎯 What You'll Learn: • Why 15% of men report having zero close friends (compared to 10% of women) and what this reveals about male emotional processing • The hidden reason suicide rates among men are 3-4 times higher in developed countries and how it connects to emotional expression patterns • Why treating men like "malfunctioning women" in therapy and relationships backfires, plus what actually works • The cortisol research showing men regulate emotions differently through physical activity and structured competition 👤 Perfect for: lifelong learners and anyone passionate about personal growth who wants to understand the real psychology behind gender differences and communication patterns. 📍 Chapters: [00:00] Adrian Wells introduces the emotional dependency paradox [01:30] The friendship crisis: why men have fewer close relationships [04:00] Suicide statistics reveal hidden emotional patterns [07:00] Why traditional emotional approaches fail men [10:00] The cortisol connection: how men actually process stress [12:00] Practical strategies that align with male psychology This isn't about excusing behavior or reinforcing stereotypes. It's about recognizing that men and women might need different tools for emotional health, and our one-size-fits-all approach isn't working. The research is pretty eye-opening. 🔔 Never miss an episode: Follow First Principles on Spotify or Apple Podcasts and turn on notifications. New episodes drop daily, your next favorite insight is one tap away. 🔍 Topics: gender psychology, male emotional health, relationship communication, suicide prevention, friendship patterns Find all episodes at First Principles --------------- Keywords: business strategy, critical thinking podcast, entrepreneurship philosophy, performance optimization, career advice, personal development, productivity science, thinking skills Learn more about your ad choices. Visit megaphone.fm/adchoices

    28 min

  6. 2D AGO

    Why Gen Z Is The Most Miserable Generation (And What Parents Don't See)

    What if everything you think you know about building wealth and raising successful kids is actually creating the most miserable generation in history? Adrian Wells breaks down Scott Galloway's explosive research on why Gen Z is drowning in depression while traditional wealth-building advice has become dangerously outdated. 🎯 What You'll Learn: • Why depression rates among teens jumped 50% between 2010 and 2020 (and what parents completely miss) • The brutal math: home prices up 400% since 1980, wages up only 25% • Why only 37% of Americans under 35 own homes compared to 69% of Boomers at that age • The new strategies that actually work when hard work alone won't cut it 👤 Perfect for: lifelong learners who want to understand what's really happening to younger generations and anyone rethinking traditional paths to success. 📍 Chapters: [00:00] Adrian Wells reveals the shocking mental health crisis nobody talks about [01:45] The wealth gap that's crushing an entire generation [04:20] Why your parents' advice about hard work is actually harmful now [06:30] Student loan debt: the 1,200% increase that changed everything [08:45] Scott Galloway's controversial take on what parents get wrong [10:30] Three strategies that actually work in today's economy This isn't another feel-good episode about following your dreams. Wells strips away the motivational fluff to show you the hard data behind why traditional success formulas are failing spectacularly. If you've wondered why young people seem so stressed despite having "every advantage," this episode connects dots you probably haven't considered. 🔔 Never miss an episode: Follow First Principles on your podcast app and turn on notifications. New episodes drop daily, your next favorite insight is one tap away. 🔍 Topics: Gen Z mental health, wealth building strategies, housing crisis, student debt, generational economics Find all episodes at First Principles --- Keywords: critical thinking podcast, billionaire mindset, thinking skills, health myths Learn more about your ad choices. Visit megaphone.fm/adchoices

    22 min

  7. 3D AGO

    The $1M Business Lie Every Guru Sells (And What Actually Works)

    What if everything you've heard about building a million-dollar business is backwards? Adrian Wells cuts through the guru BS to reveal why the "no hard work" promise is actually sabotaging entrepreneurs. Plus, the Census Bureau data that shows exactly what separates winners from the 98% who never make it. 🎯 What You'll Learn: • Why only 2% of businesses hit $1 million (and it's not what you think) • The 50-60 hour reality most successful founders won't admit • How 90% of million-dollar companies actually scale their teams • The reinvestment secret that keeps winners growing while others plateau 👤 Perfect for: lifelong learners and anyone tired of get-rich-quick schemes who wants to understand what business success actually requires. 📍 Chapters: [00:00] Adrian Wells exposes the million-dollar lie [01:45] The brutal Census Bureau truth about business failure [03:30] Why "work smarter, not harder" is incomplete advice [05:15] The hiring pattern every million-dollar business follows [07:20] The reinvestment rule winners use (60-80% back in) [09:30] What actually works when building to seven figures [11:00] Your next steps without falling for more lies The gurus selling "passive income" and "4-hour work weeks" aren't lying to hurt you. They're lying because the truth doesn't sell courses. But if you want real results instead of fairy tales, this episode gives you the data-backed foundation most entrepreneurs never get. 🔔 Never miss an episode: Follow First Principles on Spotify or Apple Podcasts and turn on notifications. New episodes drop daily, your next breakthrough insight is one tap away. 🔍 Topics: entrepreneurship, business growth, million dollar business, startup reality, business statistics Find all episodes at First Principles --- Keywords: motivation psychology, social media addiction, personal development Learn more about your ad choices. Visit megaphone.fm/adchoices

    16 min

  8. 3D AGO

    Why Your Long Runs Are Wasting Time: Dr Wright's 30-Second Solution

    What if everything you believe about fat burning is backwards? Adrian Wells sits down with Dr. Vonda Wright, who just shattered the long cardio myth with one shocking revelation: 30-second bursts can torch more fat than hour-long runs. 🎯 What You'll Learn: • Why HIIT keeps your body burning fat for 24 hours straight (the EPOC effect explained) • The exact 15-minute routine that outperforms 45 minutes of steady cardio • How 30-second intervals spike growth hormone by 450% naturally • The metabolic switch most people never activate (and how busy professionals can) 👤 Perfect for: lifelong learners tired of wasting hours on inefficient workouts and anyone who wants maximum results in minimal time. 📍 Chapters: [00:00] Adrian Wells breaks the cardio myth wide open [02:15] Dr. Wright's 30-second fat burning breakthrough [04:45] Why your hour-long runs are working against you [07:30] The growth hormone explosion nobody talks about [09:15] HIIT vs steady cardio: the metabolism showdown [11:00] Quick wins you can start using today This completely flips traditional fitness advice on its head. Dr. Wright doesn't just theorize about this stuff. She's got the research showing why short, intense bursts create a fat burning furnace that lasts all day long. The best part? You don't need a gym membership or fancy equipment. Just 30 seconds of intensity and the science takes care of the rest. 🔔 Never miss an episode: Follow First Principles on Spotify or Apple Podcasts and turn on notifications. New episodes drop daily, your next favorite insight is one tap away. 🔍 Topics: HIIT workouts, fat burning, metabolism, exercise efficiency, healthy aging Find all episodes at First Principles ------------ Keywords: first principles, critical thinking podcast, depression stories, billionaire mindset, leadership psychology, behavioral economics Learn more about your ad choices. Visit megaphone.fm/adchoices

    49 min
See All (198)

About

First Principles isn't another business podcast recycling the same startup stories. Adrian Wells takes the fundamentals that actually matter and breaks them down like you're having coffee with the smartest professor you ever had. Wells spent twelve years teaching philosophy and critical thinking before ditching the lecture hall for the microphone. Turns out, the same principles that help you think clearly about ancient Greek ethics also work pretty well for modern business decisions. Who knew? Every episode strips away the latest trends and buzzwords to focus on the core ideas that don't change. How to actually evaluate evidence when everyone's throwing around statistics. Why most "revolutionary" business advice is just old wine in new bottles. The thinking patterns that separate smart decisions from lucky guesses. You won't get hyped-up success stories or flavor-of-the-month strategies. Instead, you'll learn how to think through problems the way philosophers have for centuries, applied to the stuff that matters in your work and life right now. Multiple new episodes drop daily, so there's always something fresh when you need it. Follow now if you're ready to think better, not just think faster. Multiple new episodes daily—follow now!

Information

  • Creator
    Adrian Wells
  • Years Active
    2K
  • Episodes
    198
  • Rating
    Clean

You Might Also Like