Mikkipedia

Mikki Williden

Mikkipedia is an exploration in all things health, well being, fitness, food and nutrition. I sit down with scientists, doctors, professors, practitioners and people who have a wealth of experience and have a conversation that takes a deep dive into their area of expertise. I love translating science into a language that people understand, so while some of the conversations will be pretty in-depth, you will come away with some practical tips that can be instigated into your everyday life. I hope you enjoy the show!

  1. 4d ago

    HRT, Tirzepatide and Weight Loss After Menopause with Professor Daniela Hurtado and Dr Regina Castaneda

    Save 20% on all Nuzest Products WORLDWIDE with the code MIKKIPEDIA at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comCurranz Supplement: Use code MIKKIPEDIA to get 20% off your first order - go to www.curranz.co.nz  or www.curranz.co.uk to order yours NZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nz This week on the podcast Mikki speaks to two researchers, Professor Daniela Hurtado and Dr Regina Castaneda about the interaction between HRT and tirzepatide use. In a conversation led by Regina, they talk about differences that occur as women head through menopause, the role of HRT at mitigating some of these changes and the findings from their paper looking at how hormone therapy might enhance the therapeutic effects of tirzepatide in a postmenopausal population - discussing sex related differences. Maria Daniela Hurtado Andrade, M.D., Ph.D., is from Ecuador where she completed her medical degree at the Pontifical Catholic University. Her curiosity about the causes of obesity led her to pursue doctorate-level training in Physiology and Pharmacology at the University of Florida. Her research focused on the brain's regulation of food intake. After her doctoral training, she completed Internal Medicine training at the University of Pittsburgh Medical Center in Pittsburgh, PA, and Endocrinology Fellowship specialty training at Mayo Clinic in Rochester, MN. She joined Mayo Clinic Staff in 2019. Dr. Hurtado Andrade is interested in understanding obesity's pathophysiology to develop more effective therapeutic interventions. She is part of the Mayo Clinic Precision Medicine for Obesity program. This program aims at developing an individualized approach to the management of obesity and its complications with the goal of improving outcomes. To facilitate the generation of this new knowledge, she has focused her clinical and research efforts on specific populations: perimenopausal women and breast cancer survivors. Dr. Hurtado's contributions and expertise to the field of obesity have been recognized nationally and internationally. Regina Castaneda, MD, serves as a postdoctoral research fellow at Mayo Clinic in Florida. She is also an MSc candidate at Mayo Clinic College of Medicine and Science. Her work centres on women's health topics including obesity, diabetes, and menopause-related metabolic changes. Dr Castaneda has contributed to research examining the effects of tirzepatide on weight loss in postmenopausal women and the potential influence of hormone therapy. She is affiliated with the Division of Endocrinology, Diabetes and Metabolism at Mayo Clinic https://www.mayoclinic.org/biographies/hurtado-andrade-maria-daniela-m-d-ph-d/bio-20539671 https://www.linkedin.com/in/regina-castaneda-md-8b2371358/  Paper: https://www.thelancet.com/journals/lanogw/article/PIIS3050-5038(25)00145-1/abstract Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwilliden

  2. 6d ago

    Mini Mikkipedia - When GLP-1 Weight Loss Dims Motivation

    This episode explores emerging evidence that high-dose tirzepatide may reduce more than appetite and food noise in some people. Mikki breaks down a new case series involving three women who experienced anhedonia, a loss of motivation or interest in previously rewarding activities, despite achieving substantial weight loss. She explains the difference between “wanting” and “liking,” how GLP-1 medications may influence dopamine reward pathways, and why symptoms can feel different from depression or early medication side effects. The cases suggest that dose reduction may restore motivation without necessarily compromising weight-loss maintenance. While three cases cannot establish causation or prevalence, the findings highlight the importance of monitoring exercise, hobbies, social engagement, and overall enjoyment alongside weight, appetite, and gastrointestinal symptoms. Topics Covered What anhedonia is and how it differs from depressionThree cases involving high-dose tirzepatideThe potential role of dopamine and reward pathwaysWhy dose reduction improved symptoms in these casesPractical considerations for patients and prescribers Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwillidenNZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nzSave 20% on all Nuzest Products WORLDWIDE with the code MIKKI at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comCurranz supplement: MIKKI saves you 25% at www.curranz.co.nz or www.curranz.co.uk off your first order

  3. Jul 14

    Fueled or Fooled? Rethinking Ultra-High Carbohydrate Fuelling with Dr Dan Plews

    Save 20% on all Nuzest Products WORLDWIDE with the code MIKKIPEDIA at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.com This week on the podcast Mikki speaks to Dan Plews about his new paper ‘fuelled or fooled’ Examining the Evidence and Mechanisms Behind Ultra‑High Carbohydrate Intake in Endurance Athletes - and they discuss the latest research on carbohydrate fuelling (from the very low to the very high) and the evidence base to support ultra high carb fuelling. Dr Dan Plews is an applied sports scientist, exercise physiologist, researcher, coach and accomplished endurance athlete with more than 17 years of experience working at the highest levels of international sport. Dan is the founder of Endure IQ, an endurance education and coaching platform designed to help athletes and coaches apply sports science in the real world. He is also the co-founder of Endurox alongside Dr Adam Storey, providing evidence-based HYROX coaching and programming that combines endurance development, strength training and race-specific preparation. In addition, Dan is Science Lead at Pillar Performance Supplements, where he helps translate emerging research into practical supplementation strategies for athletes. Dan’s work brings together scientific rigour, elite-level coaching experience and first-hand understanding of what it takes to perform. His approach is centred on giving athletes the “why” behind the “what” and helping them apply science-driven strategies to train smarter and perform at their best. Paper Examining the Evidence and Mechanisms Behind Ultra‑High Carbohydrate Intake in Endurance Athletes https://link.springer.com/article/10.1007/s40279-026-02462-z https://www.endureiq.com/.  https://www.endurox.co/about  Previous appearances https://podcast.mikkiwilliden.com/360 https://podcast.mikkiwilliden.com/198  https://podcast.mikkiwilliden.com/107  https://podcast.mikkiwilliden.com/47  https://podcast.mikkiwilliden.com/31  Curranz Supplement: Use code MIKKIPEDIA to get 20% off your first order - go to www.curranz.co.nz  or www.curranz.co.uk to order yours NZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nz Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwilliden

  4. Jul 12

    Mini Mikkipedia - Why Diets Fall Apart After Week Three

    Why do people start a fat loss plan with a hiss and a roar, only to fall off a few weeks later? In this episode, Mikki unpacks the real reasons diets often derail once the novelty wears off. It is not just boredom or lack of discipline. Early scale loss slows, hunger increases, rigid rules become harder to sustain, and motivation naturally fades. Mikki explains why sustainable fat loss requires structure, flexibility, realistic expectations, and systems that work when life gets busy. She also shares practical strategies to stay consistent, including planning weekends, using simple meal templates, tracking behaviours instead of obsessing over the scale, and shifting identity from “trying to lose weight” to becoming someone who lives a fitness lifestyle. Highlights: Why motivation drops after the first few weeks of dietingHow water weight, glycogen, and scale expectations affect adherenceWhy overly rigid or repetitive plans often backfirePractical strategies for weekends, busy days, and off-plan mealsThe importance of identity, systems, and behavioural consistency Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwillidenNZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nzSave 20% on all Nuzest Products WORLDWIDE with the code MIKKI at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comCurranz supplement: MIKKI saves you 25% at www.curranz.co.nz or www.curranz.co.uk off your first order

  5. Jul 7

    Brandon Da Cruz - The Truth About Body Recomposition

    Save 20% on all Nuzest Products WORLDWIDE with the code MIKKIPEDIA at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comCurranz Supplement: Use code MIKKIPEDIA to get 20% off your first order - go to www.curranz.co.nz  or www.curranz.co.uk to order yours NZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nz This week on the podcast, Mikki speaks to fan favourite Brandon DaCruz — coach, educator, and one of the sharpest minds in physique and performance nutrition about body recomposition. While many people think of recomp purely as losing fat and gaining muscle at the same time, Brandon breaks down the three different forms it can take, and why the common claim that you cannot build muscle and lose fat simultaneously is based on an overly simplistic view of calories in, calories out. They also dive into why women may actually be better positioned for recomp than many people assume, the physiology behind this, and what Brandon sees in practice with his clients. Mikki and Brandon unpack the nutrition and training fundamentals that need to be in place, including protein intake, progressive training, and the common mistakes that stop women from seeing meaningful changes in body composition. Brandon DaCruz at his website https://www.brandondacruzfit.com/, and on Instagram @brandondacruz_ Chasing Clarity https://podcasts.apple.com/us/podcast/chasing-clarity-health-fitness-podcast/id1619611966  Brandon DaCruz is an online nutrition and physique coach, accredited nutritionist, functional nutrition and metabolism specialist, and health and fitness educator with over 16 years of coaching experience. Throughout his career, Brandon has helped more than 1,200 clients ranging from Olympia-level physique competitors and competitive athletes to business owners, executives, and lifestyle clients improve their body composition, optimize performance, and enhance their overall health. His coaching philosophy is rooted in an evidence-informed approach that combines the best available research with real-world coaching experience gained from working directly with clients in the trenches for over a decade and a half. Brandon has been featured in leading industry publications including Men’s Fitness Magazine, Muscular Development, Bodybuilding.com, and the Alan Aragon Research Review, where he served as a contributing author. Known for his ability to translate complex scientific concepts into practical, actionable strategies, Brandon specializes in helping clients lose body fat, build muscle, improve metabolic health, and create sustainable long-term results without relying on extremes or quick fixes. Brandon is also the host of the Chasing Clarity Health & Fitness Podcast, a show ranked in the top 5% of all podcasts on Spotify. Through both solo episodes and conversations with many of the industry’s leading researchers, and educators, the podcast aims to bridge the gap between complexity and clarity in health, fitness, nutrition, and physique development. Each episode is designed to empower listeners through education and provide the tools needed to make informed decisions about their health and physique goals. https://podcast.mikkiwilliden.com/270 https://podcast.mikkiwilliden.com/226  https://podcast.mikkiwilliden.com/300  https://podcast.mikkiwilliden.com/368  https://podcast.mikkiwilliden.com/416  https://podcast.mikkiwilliden.com/422  https://podcast.mikkiwilliden.com/458  Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwilliden

  6. Jul 5

    Mini Mikkipedia - Lipoedema: When Fat Loss Isn’t the Issue

    In this episode of Mini Mikkipedia, Mikki unpacks lipoedema, a chronic adipose tissue disorder that remains underdiagnosed despite affecting a significant number of women. She explains why lipoedema is not simply “stubborn fat”, but a condition involving altered fat tissue, inflammation, fibrosis, lymphatic dysfunction and pain. Mikki explores why standard diet and exercise approaches often fail to shift affected tissue, while still playing an important role in managing symptoms, inflammation, mobility and secondary weight gain. She also covers emerging evidence around low-carbohydrate and ketogenic approaches, low-impact exercise, compression and lymphatic support, specialist liposuction, and the developing conversation around GLP-1 medications. This episode is essential listening for anyone who has felt dismissed, confused, or blamed when their body has not responded as expected. Highlights: Why lipoedema is biologically different from general body fatHow low-carbohydrate approaches may help reduce pain and inflammationThe role of exercise, lymphatic flow, compression and mobilityWhy specialist liposuction is currently the most direct tissue-targeting interventionWhere GLP-1 medications may fit in future lipoedema management Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwillidenNZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nzSave 20% on all Nuzest Products WORLDWIDE with the code MIKKI at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comCurranz supplement: MIKKI saves you 25% at www.curranz.co.nz or www.curranz.co.uk off your first order

  7. Jun 30

    Choose Your Hard: Grant Schofield on Human Potential

    Save 20% on all Nuzest Products WORLDWIDE with the code MIKKIPEDIA at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.com This week on the podcast, Mikki speaks to returning guest Professor Grant Schofield about his book that has been released (and sold out in bookstores up and down the country): Choose Your Hard. We unpack this and more and it is, as always, an awesome conversation.  Grant is a Professor of Public Health at Auckland University of Technology, former Director of the University’s Human Potential Centre, former Chief Scientific Adviser to the Ministry of Education in New Zealand, co-author of four best-selling books and Chief Science Officer for PREKURE. Professor Grant’s career has focused on preventing the diseases of modern times, and seeing what it takes to help people live a long, healthy and happy life. He lives and breathes the motto “be the best you can be”, and sees this as a game-changer for the health system – capable of transforming the current health (sickness) model, to one in which we aspire to be well. He is redefining public health as the science of human potential; the study of what it takes to have a great life. Grant is well known for thinking outside the box and challenging conventional wisdom in nutrition and weight loss, as well as physical activity and exercise. He brings his fluency across several scientific disciplines – from human physiology, to psychology, to peak performance – to his role at PREKURE, where he delivers world class training in lifestyle medicine Grant’s book https://profgrantschofield.com/choose-your-hard-a-philosophical-guide-to-getting-shit-done/  You can find Grant through the following avenues. Grant Schofield Blog:https://profgrantschofield.com/ Pre Kure https://prekure.com/ https://podcast.mikkiwilliden.com/412 https://podcast.mikkiwilliden.com/324 https://podcast.mikkiwilliden.com/200 https://podcast.mikkiwilliden.com/67 https://podcast.mikkiwilliden.com/01 Curranz Supplement: Use code MIKKIPEDIA to get 20% off your first order - go to www.curranz.co.nz  or www.curranz.co.uk to order yours NZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nz Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwilliden

  8. Jun 28

    Mini Mikkipedia - How to Spot a Fad Diet Fast

    In this Mini Mikkipedia episode, Mikki unpacks the red flags that separate a legitimate nutrition approach from a fad diet dressed up in sciencey language. Starting with a brief history of some truly wild diets, from the swamp diet to tapeworms and the drinking man’s diet, she explains why modern trends may look just as absurd in hindsight. Mikki walks through the common patterns: demonising one nutrient, promising rapid results without trade-offs, relying on testimonials instead of evidence, and having no plan for what happens after the “challenge” ends. This episode gives listeners a practical toolkit for assessing diet claims, asking better questions, and avoiding programs that sell short-term scale drops without long-term strategy.  Highlights  Why fad diets often blame one nutrient for the entire obesity crisis  The difference between fat loss and early water-weight loss  Why maintenance matters more than the “before and after” photo  How sciencey language can hide weak or non-existent evidence  Why testimonials are persuasive, but not proof Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwillidenNZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nzSave 20% on all Nuzest Products WORLDWIDE with the code MIKKI at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comCurranz supplement: MIKKI saves you 25% at www.curranz.co.nz or www.curranz.co.uk off your first order

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About

Mikkipedia is an exploration in all things health, well being, fitness, food and nutrition. I sit down with scientists, doctors, professors, practitioners and people who have a wealth of experience and have a conversation that takes a deep dive into their area of expertise. I love translating science into a language that people understand, so while some of the conversations will be pretty in-depth, you will come away with some practical tips that can be instigated into your everyday life. I hope you enjoy the show!

Information

  • Creator
    Mikki Williden
  • Years Active
    2020 - 2026
  • Episodes
    487
  • Rating
    Explicit
  • Copyright
    © 2026 Mikki Williden
  • Show Website
    Mikkipedia

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