The Longevity & Lifestyle Podcast

Claudia von Boeselager
  • 4.9 (28)
  • Self-Improvement
  • Updated Weekly

Claudia von Boeselager is here to empower you to live at your best and reach your highest potential by sharing groundbreaking strategies, tools, and practices for your longevity and lifestyle from the world’s pioneering experts. For more, visit: LLinsider.com Welcome to The Longevity & Lifestyle Podcast! Claudia is on a mission to help 1 billion people optimize their lives and reach their fullest potential so that they can make a positive impact in the world! Tune in to learn how to increase your healthspan, improve the quality of your life and lifestyle also around entrepreneurship, managing personal finances and investing, and much more. Topics include how to optimize your health in areas such as sleep, nutrition, cognition, metabolic health, reversing diabetes, intermittent fasting, biomarkers, gut health, hormones, the female biorhythm, skin, hair, biohacking tips, supplements, mastering your mindset, improve your relationships and overall happiness, meditation, how to perform better in business, optimize your daily routines, achieve peak performance, biohacking your age, and more. Claudia is a Peak Performance Coach and Serial Entrepreneur passionate about helping you thrive in all areas of your life & business! She knows what it’s like to feel close to burnout and not be at your best. Thanks to 10+ years of research, countless interviews with global pioneers, and hundreds of thousands spent, she continues to uncover how you, too, can achieve peak performance to live your life at its best - all while having lots of fun! So make sure to TUNE IN and start living the best version of yourself!

  1. 9h ago

    #259 Jamie Clements — How to Breathe Better: Stress Resilience, Altered States & Human Potential

    What if the constant pressure to improve yourself is reinforcing the anxiety you are trying to escape? In this episode of the Longevity & Lifestyle Podcast, Claudia welcomes Jamie Clements, breathwork facilitator, speaker, educator, and founder of The Breath Space. Jamie shares how anxiety, depression, and panic attacks led him away from a high-performing career in finance and technology and toward a deeper exploration of breath, nervous system health, consciousness, and human potential. He explains how breathing influences the autonomic nervous system, why dysfunctional breathing can reinforce stress and anxiety, and how simple changes in breathing speed, depth, and rhythm can shift how we feel and perform. They also explore carbon dioxide tolerance, nasal breathing, breath holding, sleep apnea, altered states of consciousness, trauma-aware breathwork, and the risks of practicing deeper techniques without the right preparation or facilitator. This conversation also challenges the modern obsession with optimization. Jamie explains why high performers often find rest uncomfortable, how achievement can become tied to self-worth, and why slowing down may be one of the most powerful ways to improve creativity, energy, and performance. IN THIS EPISODE • How anxiety and panic attacks led Jamie to breathwork • Why the breath directly influences the nervous system • Signs that you may be breathing dysfunctionally • Why carbon dioxide is essential for oxygen delivery • How breath holding may build stress resilience • Nasal breathing, mouth breathing, and cognitive health • Box breathing, extended exhales, and the physiological sigh • How breathwork can create altered states of consciousness • Trauma, emotional release, and breathwork safety • Why high performers struggle to rest • The link between achievement and self-worth • Why you do not need fixing • How slowing down can improve productivity TIMESTAMPS 00:00 Introduction 03:44 Jamie’s experience with anxiety and panic attacks 06:15 Losing his job and discovering a different path 09:26 Why we underestimate the power of breathing 12:15 Ancient breathwork traditions 15:43 How breathing controls the nervous system 18:06 Using breath to change your internal state 19:33 CO2 tolerance and stress resilience 24:58 Signs you may be breathing incorrectly 27:39 The three levels of breathwork 31:13 Trauma release and breathwork safety 33:54 What an altered-state breathwork session feels like 38:29 Why high performers struggle to slow down 41:43 Purpose, ambition, and self-worth 43:24 Creating work-life harmony 48:57 The Breath Space 50:33 Why you do not need fixing ABOUT JAMIE CLEMENTS Jamie Clements is a breathwork facilitator, speaker, educator, and founder of The Breath Space. His work brings together functional breathing, neuroscience, psychology, trauma-aware practice, ancient wisdom, and nervous system regulation. Through retreats, workshops, courses, and corporate experiences, Jamie helps people move from anxiety, burnout, and disconnection toward greater awareness, resilience, and meaning. Subscribe to the Longevity & Lifestyle Podcast for evidence-informed conversations with leading experts in health, longevity, consciousness, and human performance. Please share this episode with someone who feels overwhelmed, chronically stressed, or unable to slow down. #JamieClements #Breathwork #NervousSystem #Anxiety #StressRelief #MentalHealth #Consciousness #TraumaHealing #Burnout #LongevityPodcast

  2. Jul 15

    #258 Jay Campbell — Peptides, Fake Products, GLP-1 Mistakes, Quality Testing & His Top Supplements

    What if the peptides and supplements you are taking contain far less than the label claims? In this episode of the Longevity & Lifestyle Podcast, Claudia welcomes back Jay Campbell, bestselling author, peptide educator, and co-founder of BioLongevity Labs and BioLongevity Supplements. Jay reveals why he believes much of the peptide and supplement market is filled with counterfeit, underdosed, or poorly tested products. He explains how consumers can investigate batch numbers, certificates of analysis, ingredient dosages, and third-party testing before trusting a product. They also explore the rapidly changing regulatory landscape around peptides and GLP-1 medications, why many people experience avoidable side effects, and why peptides should be treated as tools rather than shortcuts. Jay shares the foundations that should come first, including resistance training, adequate protein, quality sleep, metabolic health, and hormonal balance. He also reveals the three supplements he personally considers most noticeable for energy, gut health, and cognitive performance. IN THIS EPISODE • Why peptide quality and testing matter • How counterfeit and underdosed products enter the market • What batch numbers and certificates of analysis can reveal • Why proprietary blends should raise questions • The biggest mistakes people make with GLP-1 medications • Why peptides are not magic bullets • How to assess supplement labels and active dosages • When supplements should be taken fasted or with food • Jay’s top products for energy, gut health, and focus • Why education matters more than hype TIMESTAMPS 00:00 Introduction 02:26 Why Jay created BioLongevity Supplements 04:13 Peptide regulation and the changing market 11:02 Retatrutide, access, and pharmaceutical control 13:34 What peptides are and how they work 15:31 The history of peptide and bioregulator research 23:06 The future of retatrutide regulation 27:41 Fake and underdosed peptide products 29:08 How to verify peptide quality 32:27 Why many people use GLP-1s incorrectly 34:07 Creating stronger peptide testing standards 38:55 Why peptides are tools, not shortcuts 43:43 Why the supplement industry is broken 51:26 How to read a supplement label 54:01 Active ingredients and proprietary blends 58:15 How oral supplements are absorbed 59:55 Jay Campbell’s top three supplements 01:02:08 Jay’s final message JAY’S TOP THREE SUPPLEMENTS Shred Max Designed to support mitochondrial energy, exercise performance, sweating, and force production. BioGut Pro Formulated to support the gut microbiome, reduce inflammation, and address digestive imbalance. BioMind A nootropic blend designed to support calm, precise focus during demanding cognitive tasks. Explore BioLongevity Supplements and receive 20% off with code CLAUDIA20: https://biolongevitysupplements.com/shop Subscribe to the Longevity & Lifestyle Podcast for more conversations with leading experts in longevity, health optimization, and human performance. Disclaimer: This podcast is for educational and informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before using peptides, supplements, or medications, or changing your health protocol. #JayCampbell #Peptides #Supplements #GLP1 #BioLongevity #HealthOptimization #GutHealth #BrainHealth #Mitochondria #Longevity

  3. Jul 9

    #257 Dr. Dale Bredesen — Can Alzheimer's Be Prevented? New Trial Results & Brain Biomarkers

    Ready to unlock your brain’s superpower? Download my free 5-Minute Brain Blueprint to boost mental clarity, sharpen focus, and support lifelong cognitive vitality → https://longevity-and-lifestyle.com/BRAIN What if cognitive decline is not as inevitable as we have been told? In this episode of the Longevity & Lifestyle Podcast, I welcome back Dr. Dale Bredesen, internationally recognized neurologist, bestselling author, and pioneer in the prevention and reversal of cognitive decline. Dr. Bredesen shares the findings from his latest randomized controlled trial, in which 90% of participants receiving a precision medicine protocol improved. We explore why Alzheimer’s may begin decades before symptoms appear, the biomarkers that can help identify risk earlier, and the lifestyle and medical factors that may influence cognitive health. We also discuss the role of sleep, insulin resistance, inflammation, toxins, ketones, peptides, stem cells, GLP-1 medications, psychedelics, and neuroplasticity. This conversation offers an important message: the earlier we understand what is driving cognitive decline, the greater the opportunity to act. In this episode, you’ll learn: • Why Alzheimer’s may begin decades before symptoms • What Dr. Bredesen’s latest trial revealed • The stages from prevention to dementia • Blood biomarkers linked to early decline • Insulin resistance, ketones, and brain energy • Sleep apnea and long-term brain health • Why there is no single cure TIMESTAMPS 00:00 Introduction 03:37 The Alzheimer’s trial where 90% improved 06:35 What drives cognitive decline 12:01 Why Alzheimer’s is no longer viewed as hopeless 16:08 The four stages of cognitive decline 18:22 Blood tests that may reveal risk earlier 22:22 The key drivers of Alzheimer’s 23:36 The seven foundations of brain health 25:53 Sleep targets for cognitive longevity 28:27 GLP-1s and Alzheimer’s risk 31:35 Peptides for brain health 35:59 Stem cells, exosomes, and regenerative medicine 39:32 Is there hope at every stage? 40:45 Inside the randomized clinical trial 46:18 Psychedelics and neuroplasticity 52:31 Dr. Bredesen’s final message CONNECT WITH DR. DALE BREDESEN Website: https://www.drbredesen.com Free cognitive assessment: https://www.mycqtest.com Brain biomarker testing: https://www.getabrainscan.com CONNECT WITH CLAUDIA Website: https://longevity-and-lifestyle.com Instagram: https://www.instagram.com/longevityandlifestyle LinkedIn: https://www.linkedin.com/in/claudiavonboeselager YouTube: https://www.youtube.com/@LongevityandLifestyle Subscribe to the Longevity & Lifestyle Podcast for more conversations with leading scientists, physicians, founders, and innovators shaping the future of health and human performance. #DaleBredesen #Alzheimers #BrainHealth #CognitiveDecline #DementiaPrevention #Longevity #PrecisionMedicine #Neuroplasticity #HealthyAging #LongevityPodcast

  4. Jul 1

    #256 Dr. Ian White — Repairing the Aging Body: Amniotic Fluid, Muse Cells & Regenerative Medicine

    What if the real key to longevity is not just preventing damage - but restoring the body’s ability to repair itself? In this episode, I sit down with Dr. Ian White, a leading expert in regenerative medicine, stem cell biology, tissue regeneration, and longevity science. We explore how amniotic fluid, Muse cells, and regenerative signaling may help support healing, reduce inflammation, and change the future of longevity medicine. We also break down what regenerative medicine actually is, how it differs from the way most people talk about stem cells, what matters most for safety, and how this field could reshape the way we think about aging and recovery. In this conversation, we cover: 00:00 - The accidental discovery that changed regenerative science 00:40 - Could the answer to longevity begin before birth? 02:23 - Dr. Ian White’s path into regenerative medicine 05:13 - Why some animals regrow tissue and humans do not 07:26 - What changes in the body’s repair systems with age 09:29 - Why amniotic fluid is so scientifically interesting 12:55 - What regenerative medicine really means 15:05 - Longevity, healing, and the biology of repair 16:30 - Stem cells vs regenerative medicine 21:05 - Regulation, safety, and responsible clinical use 24:13 - Tissue repair and real-world applications 28:37 - Brain health and regenerative medicine 31:39 - Rejuvenation and the future of anti-aging medicine 39:05 - Muse cells and why they matter 43:40 - Who may benefit most from these therapies 46:37 - How to approach regenerative medicine responsibly 50:23 - Space aging research and the future of longevity science 54:25 - Final thoughts on healing, aging, and what comes next If you enjoyed this episode, subscribe and share it with someone serious about living longer, healthier, and better. #Longevity #RegenerativeMedicine #StemCells #HealthyAging #Biohacking #TissueRepair #AntiAging #HealthOptimization

  5. Jun 26

    #255 Dr. Alexander Grinberg — Peptides Without Hype: What Actually Works & The Future of Longevity

    In this episode of the Longevity & Lifestyle Podcast, Claudia von Boeselager sits down with Dr. Alexander Grinberg, one of the few physicians who has worked with peptide therapeutics since the 1980s. Long before peptides became a social media trend, Dr. Grinberg was involved in clinical research using peptide bioregulators in patients with autoimmune disease, immune dysfunction, radiation exposure, viral illnesses, and regenerative medicine. Drawing on more than 35 years of clinical and scientific experience, he explains what peptides can realistically do, where the evidence is strongest, and why personalized medicine matters far more than following influencer protocols. They discuss the biggest mistakes people make when self-experimenting with peptides, why proper diagnostics are essential before starting treatment, cancer considerations, mitochondrial health, immune function, bioregulators, GLP-1 medications, and what the future of peptide medicine may look like. Whether you're curious about BPC-157, GHK-Cu, Epitalon, MOTS-c, SS-31, or simply want to separate scientific evidence from marketing hype, this conversation offers one of the most balanced and informative discussions on peptides available today. In this episode you'll learn: Why peptides are far more powerful than most people realizeThe biggest risks of self-prescribing peptide protocolsWho should avoid certain peptides altogetherThe blood tests and biomarkers to check before startingWhy longevity treatments should always be personalizedThe fascinating history of peptide medicine dating back to the 1980sHow peptides may support healthy aging, immune health and regenerative medicineThe future of peptide therapeutics and precision longevity medicine Timestamps 00:00 Introduction 01:18 Why peptides need to be treated like real medicines 03:30 Blood tests and biomarkers before using peptides 05:45 Cancer risks, contraindications and safety 07:25 How Dr. Grinberg became one of the first peptide physicians 12:10 The history of peptide research in the Soviet Union 13:15 Personalized peptide medicine explained 19:20 The dangers of self-experimenting with peptides 20:00 Growth hormone peptides and cancer concerns 22:00 How physicians evaluate peptide protocols 25:00 Bioregulators vs modern peptides 30:00 Autoimmune disease and peptide therapies 36:00 Mitochondrial peptides and healthy aging 42:00 GLP-1 peptides beyond weight loss 48:00 The future of peptide medicine 55:00 Final thoughts If you enjoyed this episode, please subscribe, leave a review, and share it with someone interested in longevity, regenerative medicine, and evidence-based health optimization. Connect with Claudia von Boeselager Website: https://llinsider.com Newsletter: https://llinsider.com/newsletter Follow the Longevity & Lifestyle Podcast for weekly conversations with the world's leading experts in longevity, health optimization, and performance. #Longevity #Peptides #Biohacking #HealthyAging #PrecisionMedicine

  6. Jun 19

    #254 Roger Love — Your Voice Is Shaping Your Life: Confidence, Authenticity & Human Connection

    My guest today is Roger Love - one of the world’s most renowned voice coaches. He has worked with top performers, executives, actors, and public figures, and his work sits at the intersection of voice, confidence, emotional expression, breath, nervous system regulation, communication, and identity. In this conversation, we explore how the way you sound shapes the way people perceive you and the way you perceive yourself. We get into Roger’s framework for mastering the five core voice variables — pitch, pace, tone, melody, and volume — and why most people unknowingly sound monotone, anxious, apologetic, or less confident than they really are. He explains how voice patterns influence emotion, why public speaking fear is really fear of judgment, and how changing the sounds of confidence can actually help build confidence in real life. We also discuss the connection between voice and longevity, Roger’s work using singing and airflow to help people with stuttering and post-stroke speech challenges, and why he believes your voice may be one of the most overlooked tools for improving relationships, self-expression, business, and quality of life. This episode is for anyone who wants to communicate with more clarity, warmth, authority, and authenticity. Timestamps 00:00 Why your voice may be shaping your entire life 00:59 Intro to Roger Love and why voice matters beyond performance 02:54 Roger’s origin story — singing, happiness, and becoming a voice coach at 16 08:02 The 5 core voice variables: pitch, pace, tone, melody, and volume 09:50 How emotion shapes the way you should speak — fast vs. slow, loud vs. soft 11:18 Why people remember how you make them feel more than the words you say 16:00 Why monotone voices lose people — and how melody creates engagement 19:23 The “leading tone” technique to keep people listening and prevent interruptions 20:02 How vocal musicality creates emotion, attention, and connection 21:20 Voice, relationships, and longevity — Roger’s perspective on why communication keeps us young 23:14 Roger’s documentary Find Your Voice and the story of helping a lifelong stutterer 25:23 “Solid airflow” and Roger’s approach to stuttering and speech transformation 26:12 Singing, stroke recovery, and helping his mother speak again 27:32 Why public speaking fear is really fear of being judged 28:52 “The sound creates the reality” — how confident speech builds real confidence 46:32 Why voice is a learnable skill, not a fixed trait 47:34 Why nobody is stuck with the voice they have 49:37 The voice makeover idea that could change your life #RogerLove #CommunicationSkills #PublicSpeaking #Confidence

  7. Jun 12

    #253 Dr. Darshan Shah — Become the CEO of Your Health Before Disease Becomes Your Diagnosis

    Dr. Darshan Shah is a board-certified surgeon, longevity physician, entrepreneur, and founder of Next Health. After performing more than 20,000 surgeries and training at the Mayo Clinic, Darshan realized something most people never hear from the medical system: treating disease is not the same as creating health. In this episode, he shares the personal health crisis that changed his life, the longevity pyramid he uses with patients, the key biomarkers and scans to know before disease appears, why muscle and metabolic health matter so much, how toxins and hormone disruption are affecting people earlier than ever, and what hyper-preventive medicine may look like in the years ahead. Timestamps 00:00 Intro 01:21 Darshan’s personal health crisis despite medical success 05:51 Why modern medicine treats disease but misses true health 09:51 The longevity pyramid and the few habits that move the needle most 13:27 Why tracking glucose can change how you eat 14:11 Why sitting all day harms metabolic health 17:29 Why muscle and grip strength predict longevity 19:46 DEXA scans, body composition, and key longevity baselines 22:14 The blood markers to know before disease shows up 26:51 Functional medicine testing - gut health, hormones, and stress 30:54 Microplastics, toxins, and why hormones are getting disrupted earlier 35:24 How to detox your home without getting overwhelmed 36:48 Hyper-preventive medicine for heart disease, cancer, brain health, and lung health 43:15 Peptides, stem cells, and when advanced therapies actually make sense 44:04 Why chronic disease may not need to be your destiny 45:24 What’s next for Darshan and Next Health #Longevity #HealthOptimization #MetabolicHealth #PreventiveMedicine #Biohacking

  8. Jun 5

    #252 Dr. Bilal Chughtai — The Overlooked Bladder Health Problem That Can Affect Longevity

    Dr. Bilal Chughtai is a board-certified urologist and expert in women’s urinary health, recurrent urinary tract infections, the urinary microbiome, and preventative urology. In this episode, Claudia speaks with Dr. Chughtai about why bladder health deserves far more attention in the longevity conversation - especially for women dealing with recurrent UTIs, menopause, changing hormones, and the often-overlooked effects urinary health can have on cognition, confidence, intimacy, travel, and quality of life. They explore why UTIs are so common in women, why they often become more frequent with age, how estrogen loss during menopause changes the bladder environment, and why repeated antibiotic use may not always be the best long-term solution. They also discuss the emerging science of the urinary microbiome, the link between UTIs and neurological symptoms in older adults, and practical tools that may help reduce recurrence and support long-term urinary health. We discuss: Why bladder health matters for longevity and healthy agingWhy women are more prone to recurrent UTIsThe connection between menopause, estrogen decline, and bladder healthWhy UTIs can sometimes show up as confusion or delirium in older adultsThe urinary microbiome and how the science is evolvingThe downside of repeated antibiotic useCranberry, D-mannose, vaginal estrogen, pelvic floor therapy, and other prevention toolsPractical habits to support urinary health over time Timestamps 00:00 Intro 01:23 Why bladder health matters for longevity 02:30 Why UTIs are so common in women 03:39 UTIs, confusion, and cognitive symptoms in older adults 05:01 What happens during a UTI 06:52 What healthy bladder aging looks like 07:24 Why urinary health needs a personalized approach 08:48 Hydration and bladder health 09:39 The problem with repeated antibiotic use 11:44 Cranberry and non-antibiotic prevention tools 13:59 D-mannose and what the evidence says 18:02 Stress, sleep, exercise, and urinary function 19:19 Menopause, estrogen, and bladder health 21:19 Pelvic floor therapy and age-related changes 23:00 Symptoms to raise with your doctor early 24:32 Daily urinary health habits 30:06 Future innovations in bladder health 31:54 First steps for recurrent UTIs 34:26 Where to find Dr. Bilal Chughtai 34:55 Final thoughts Ready to upgrade your health, energy, and longevity? Download my free 10 Life & Longevity Hacks Playbook and start living smarter, stronger, and longer → https://longevity-and-lifestyle.com/freebie If you enjoy science-backed conversations on longevity, metabolic health, biohacking, brain health, women’s health, and performance optimization, subscribe and turn on notifications so you don’t miss upcoming episodes. #longevity #womenshealth #uti #menopause #bladderhealth #healthyaging #microbiome #preventativehealth #urology

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About

Claudia von Boeselager is here to empower you to live at your best and reach your highest potential by sharing groundbreaking strategies, tools, and practices for your longevity and lifestyle from the world’s pioneering experts. For more, visit: LLinsider.com Welcome to The Longevity & Lifestyle Podcast! Claudia is on a mission to help 1 billion people optimize their lives and reach their fullest potential so that they can make a positive impact in the world! Tune in to learn how to increase your healthspan, improve the quality of your life and lifestyle also around entrepreneurship, managing personal finances and investing, and much more. Topics include how to optimize your health in areas such as sleep, nutrition, cognition, metabolic health, reversing diabetes, intermittent fasting, biomarkers, gut health, hormones, the female biorhythm, skin, hair, biohacking tips, supplements, mastering your mindset, improve your relationships and overall happiness, meditation, how to perform better in business, optimize your daily routines, achieve peak performance, biohacking your age, and more. Claudia is a Peak Performance Coach and Serial Entrepreneur passionate about helping you thrive in all areas of your life & business! She knows what it’s like to feel close to burnout and not be at your best. Thanks to 10+ years of research, countless interviews with global pioneers, and hundreds of thousands spent, she continues to uncover how you, too, can achieve peak performance to live your life at its best - all while having lots of fun! So make sure to TUNE IN and start living the best version of yourself!

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