The Smartest Doctor in the Room

Dr. Dean Mitchell

A combination of a lively, personal and in-depth interview with top healthcare specialists. The average listener may not have access to the expert medical advice athletes, actors and CEO’s have today, but on this show, they will learn the key facts to know about any health conditions that they or their family deal with. Hosted by Dr. Dean Mitchell. https://www.mitchellmedicalgroup.com/

  1. May 19

    Ep. 224 - Using a Home Narrowband UV Light to Treat Autoimmune Diseases

    Dr. Dean Mitchell speaks with Professor Prue Hart, an international expert in photoimmunology from the Kids Research Institute in Australia, who has spent 30 years studying how UV light interacts with the human immune system. Their conversation covers the science behind why the skin, as the body's largest immune organ, can generate systemic effects well beyond where light is applied. Professor Hart explains her clinical trial using narrowband UVB therapy in patients with clinically isolated syndrome, an early precursor to multiple sclerosis. The trial, which enrolled 20 drug-free patients, tracked immune cell function, inflammatory protein markers, and patient wellbeing over 12 months. The findings suggested that two months of phototherapy produced measurable changes in immune activity lasting at least 90 days, alongside improvements in energy, mood, and social functioning. The conversation also addresses the practical dimensions of this therapy, including its long-standing use in dermatology for psoriasis, its safety profile relative to biologic medications, and the growing availability of at-home narrowband UVB devices. Professor Hart and Dr. Mitchell also examine the role of vitamin D as a biomarker rather than a therapeutic agent, the epidemiological connection between latitude and autoimmune disease rates, and how sunscreen use and sun avoidance factor into the broader picture of health. Connect with Prue Hart: Inquiries and Orders - orders@cytokind.net Website: www.cytokind.net Facebook: https://www.facebook.com/cytokind Schedule 10 minute Discovery Call: https://calendly.com/d/crkh-wv5-vdv/10-min-discovery-call Email me at jmacmahon@cytokind.net Online Fatigue Severity Scale (FSS) Survey - https://cytokind-fatigue.netlify.app/ Contact Dr. Mitchell: Email: care@mitchellmedicalgroup.com Website Instagram YouTube Facebook LinkedIn Order your copy of Dr. Mitchell’s latest book, Conquering Candida, here. Be sure to visit ImmunoLytics & use coupon code SmartestDoc for 5% off

    51 min
  2. May 12

    Ep. 223 - Auto Brewery Syndrome: When Your Gut Produces Alcohol Without a Single Drink

    Dr. Dean Mitchell speaks with Dr. Barbara Cordell, author of "My Gut Makes Alcohol" and a researcher with over 30 published academic papers, including three specifically on auto brewery syndrome. Dr. Cordell brings both professional expertise and personal experience to the conversation, having navigated the condition through her husband's years-long medical ordeal before a diagnosis was ever reached. The discussion covers what auto brewery syndrome actually is, which organisms are responsible for fermentation in the gut, and why factors like antibiotic use, high-carbohydrate diets, proton pump inhibitors, and processed food intake appear to create conditions for the syndrome to develop. Dr. Mitchell draws parallels to candida overgrowth and small intestinal fungal overgrowth, and both physicians explore how these conditions may exist on a shared spectrum of microbiome dysregulation. Practical topics include the published diagnostic protocol involving glucose challenge and blood alcohol testing in an observed clinical setting, the role of culture-based antifungal treatment, dietary management during recovery, and why fermented foods may not be appropriate for certain patients. Dr. Cordell also addresses the legal consequences many patients face, including DUI charges, and describes her work testifying as an expert witness and connecting affected individuals with attorneys familiar with the condition. Contact Dr. Mitchell: Email: care@mitchellmedicalgroup.com Website Instagram YouTube Facebook LinkedIn Order your copy of Dr. Mitchell’s latest book, Conquering Candida, here. Be sure to visit ImmunoLytics & use coupon code SmartestDoc for 5% off

    40 min
  3. May 5

    Ep. 222 - Poisoned: One Attorney's Battle With Toxin Exposure and How He Survived and Is Now Making a Difference

    Dr. Dean Mitchell sits down with Alan Bell, a practicing attorney who spent years in a wheelchair tethered to an oxygen tank after a debilitating toxic chemical exposure left him unrecognized and undiagnosed by hundreds of physicians, including specialists at Mayo Clinic, Cleveland Clinic, and the National Jewish Immune Hospital. Bell's story moves from early flu-like symptoms to grand mal seizures, extreme chemical hypersensitivity, and years of near-total isolation in a specially built structure in the desert. Bell details his time at the Environmental Health Center in Dallas under Dr. William Rea, a self-contained treatment facility that served patients with severe chemical and environmental sensitivities at a time when conditions like mast cell activation syndrome and CIRS were not yet part of mainstream medicine. He describes the psychological and social dimensions of an illness that was broadly dismissed by the medical establishment, and how connection with fellow patients provided a rare sense of being understood. Now a faculty member at both the University of Miami and Boston University Schools of Medicine, Bell teaches medical students about the environment's impact on human health. He also takes on toxic tort cases nationally, working alongside attorneys from prominent environmental litigation practices. The conversation covers the legal landscape for tenants and workers dealing with mold or chemical exposure, the evidentiary challenges of these cases, and Bell's core advice: pay attention to when and where symptoms improve or worsen, and treat the body itself as the most reliable diagnostic tool available. Contact Dr. Mitchell: Email: care@mitchellmedicalgroup.com Website Instagram YouTube Facebook LinkedIn Order your copy of Dr. Mitchell’s latest book, Conquering Candida, here. Be sure to visit ImmunoLytics & use coupon code SmartestDoc for 5% off

    48 min
  4. Apr 28

    Ep. 221 - From Antihistamines to Immunotherapy: A Practical Plan for Managing Seasonal Allergies

    Dr. Dean Mitchell walks through a complete approach to seasonal allergy management, starting with why certain antihistamines are better suited for spring pollen symptoms than others. He explains the differences between first and second-generation antihistamines, flags specific drug combinations to avoid, and covers proper technique for nasal sprays and eye drops, including common mistakes that reduce effectiveness or cause harm over time. The conversation then shifts to the longer-term option most patients never hear about. Dr. Mitchell shares the history behind sublingual allergy drops, how they work through gradual immune desensitization, and why he transitioned away from allergy injections after a serious patient reaction in 1998. He draws on more than two decades of clinical experience using sublingual therapy for pollen, animal, and food allergies. He also addresses why sublingual immunotherapy remains hard to find in conventional allergy practices, pointing to insurance reimbursement structures as the primary barrier rather than any question of safety or effectiveness. Patient compliance data and published research are referenced to support the comparison between the two approaches. Contact Dr. Mitchell: Email: care@mitchellmedicalgroup.com Website Instagram YouTube Facebook LinkedIn Order your copy of Dr. Mitchell’s latest book, Conquering Candida, here. Be sure to visit ImmunoLytics & use coupon code SmartestDoc for 5% off

    20 min
  5. Apr 21

    Ep. 220 - How Your Diet is Affected by Your Specific Gene Variations

    Dr. Dean Mitchell sits down with Dr. Ahmed El-Sohemy, professor and research chair in nutrigenomics at the University of Toronto and founder of Nutrigenomix, to examine why individuals respond so differently to the same foods, and what genetic testing can now tell us about those differences. The conversation moves through four key genes studied in the field. The MTHFR gene, which affects folate metabolism in roughly a third of the population, is addressed directly, including why it has been overhyped and what the clinical evidence actually supports regarding methylated supplements and homocysteine. The ACE gene and its connection to salt-sensitive hypertension is examined using data from a large JAMA study showing that approximately 20 to 30 percent of individuals see blood pressure move in the opposite direction when sodium is reduced. The GLUT2 gene, originally thought to influence glucose metabolism, turns out instead to be linked to sugar cravings through dopamine receptor pathways. And the CYP1A2 gene, which governs caffeine metabolism, is discussed at length: roughly half the population are slow metabolizers, and for that group, consuming more than two small cups of coffee per day has been associated with increased cardiovascular risk and impaired athletic performance. Dr. El-Sohemy also addresses a recent paper on the APOE4 gene, associated with elevated Alzheimer's and cardiovascular risk, where evidence suggests individuals carrying that variant may respond more favorably to higher protein intake including animal protein. The discussion closes with a practical look at how Nutrigenomix testing works, why it is offered exclusively through licensed healthcare professionals, and the meaningful differences between a clinically validated panel and consumer ancestry platforms when it comes to nutritional markers. Support the Show on Patreon - Join here! If you’d like to go deeper beyond the weekly episodes, you can become a member of The Smartest Doctor In The Room Patreon community. Patreon members receive access to bonus content, extended discussions, and thoughtful medical Q&As that expand on the topics covered on the show. It’s a space for listeners who want more context, nuance, and ongoing conversation around health and medicine. Your support helps keep the podcast independent and allows Dr. Mitchell to continue sharing honest, experience-based insight without outside influence. Contact Dr. Mitchell: Email: care@mitchellmedicalgroup.com Website Instagram YouTube Facebook LinkedIn Order your copy of Dr. Mitchell’s latest book, Conquering Candida, here. Be sure to visit ImmunoLytics & use coupon code SmartestDoc for 5% off

    56 min
  6. Apr 14

    Ep. 219 - The Hidden Meaning of Itching: When Your Skin is Trying to Tell You Something

    Dr. Dean Mitchell takes a closer look at pruritus, a symptom often dismissed but capable of significantly disrupting sleep, focus, and quality of life. He explains how itching is not just a skin issue, but a neurological signal that can reflect irritation, inflammation, or deeper systemic concerns. The conversation walks through common causes such as contact dermatitis, eczema, and allergic reactions, as well as less obvious contributors including infections, medications, and environmental exposures. Dr. Mitchell also highlights how certain conditions like liver dysfunction, kidney disease, blood disorders, and even malignancies can present with persistent itching. He outlines key warning signs that warrant further evaluation, including itching without a rash, worsening symptoms at night, and associations with fatigue, weight loss, or fever. Treatment approaches are framed in layers, emphasizing the importance of identifying the root cause rather than relying on one-size-fits-all solutions. The discussion reinforces a central message: persistent itching should be approached thoughtfully, with both patient and physician working together to investigate beyond the surface. Support the Show on Patreon - Join here! If you’d like to go deeper beyond the weekly episodes, you can become a member of The Smartest Doctor In The Room Patreon community. Patreon members receive access to bonus content, extended discussions, and thoughtful medical Q&As that expand on the topics covered on the show. It’s a space for listeners who want more context, nuance, and ongoing conversation around health and medicine. Your support helps keep the podcast independent and allows Dr. Mitchell to continue sharing honest, experience-based insight without outside influence. Contact Dr. Mitchell: Email: care@mitchellmedicalgroup.com Website Instagram YouTube Facebook LinkedIn Order your copy of Dr. Mitchell’s latest book, Conquering Candida, here. Be sure to visit ImmunoLytics & use coupon code SmartestDoc for 5% off

    27 min
3.8
out of 5
13 Ratings

About

A combination of a lively, personal and in-depth interview with top healthcare specialists. The average listener may not have access to the expert medical advice athletes, actors and CEO’s have today, but on this show, they will learn the key facts to know about any health conditions that they or their family deal with. Hosted by Dr. Dean Mitchell. https://www.mitchellmedicalgroup.com/

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