Proteomics in Proximity

Olink Proteomics
  • 5.0 (6)
  • Life Sciences
  • Updated Biweekly

Proteomics in Proximity discusses the intersection of proteomics with genomics for drug target discovery, the application of proteomics to reveal disease biomarkers, and current trends in using proteomics to unlock biological mechanisms. Co-hosted by Olink's Dale Yuzuki, Cindy Lawley and Sarantis Chlamydas.

  1. Hype to Evidence: What FDA, XPRIZE and ARPA-H Are Teaching Us About Longevity

    5d ago

    Hype to Evidence: What FDA, XPRIZE and ARPA-H Are Teaching Us About Longevity

    Welcome to the Olink® Proteomics in Proximity podcast!   Below are some useful resources mentioned in this episode:    Reagan-Udall Foundation at FDA Gerotherapeutics in Aging Event Recording available: Affecting the Aging Trajectory:  Regulatory Constructs for Gerotherapeutic Drug, Biologic and Device Development https://reaganudall.org/news-and-events/events/affecting-aging-trajectory-regulatory-constructs-gerotherapeutic-drug   UK Biobank Pharma Proteomics Project (UKB-PPP), one of the world’s largest scientific studies of blood protein biomarkers conducted to date, https://www.ukbiobank.ac.uk/learn-more-about-uk-biobank/news/uk-biobank-launches-one-of-the-largest-scientific-studies    UK Biobank Pharma Proteomics Project Full Cohort Study:  Thermo Fisher Scientific’s Olink Platform Selected for World’s Largest Human Proteome Study https://ir.thermofisher.com/investors/news-events/news/news-details/2025/Thermo-Fisher-Scientifics-Olink-Platform-Selected-for-Worlds-Largest-Human-Proteome-Study/default.aspx Organ Ageing and Ageing Clock Publications leveraging Olink Proteomics: Oh, H.SH et al. (2025). Plasma proteomics links brain and immune system aging with healthspan and longevity. Nat Med 31, 2703–2711. https://doi.org/10.1038/s41591-025-03798-1 Goeminne et al (2024). Plasma protein-based organ-specific aging and mortality models unveil diseases as accelerated aging of organismal systems Cell Metabolism, 37, 205-222.e6 Argentieri, M.A et al. (2024). Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations. Nat Med 30, 2450–2460. https://doi.org/10.1038/s41591-024-03164-7 Additional publication of interest:  Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens. Kardell O (2023). J Proteome Res. 2024 Jan 5;23(1):117-129. https://pubs.acs.org/doi/10.1021/acs.jproteome.3c00473 Subscribe to the podcast on your favorite player or app: Apple Podcasts: https://apple.co/3T0YbSm   Spotify Podcasts: https://open.spotify.com/show/2sZ2wxO...   Google Podcasts: https://podcasts.google.com/feed/aHR0...   Amazon Music: https://music.amazon.com/podcasts/d97...   Podcast Addict: https://podcastaddict.com/podcast/409...   Deezer:

    40 min
  2. When Proteins Tell Time: Biological Aging with Tony Wyss-Coray

    Jun 9

    When Proteins Tell Time: Biological Aging with Tony Wyss-Coray

    Welcome to the Olink® Proteomics in Proximity podcast! Below are some useful resources mentioned in this episode: UK Biobank Pharma Proteomics Project (UKB-PPP), one of the world’s largest scientific studies of blood protein biomarkers conducted to date. https://www.ukbiobank.ac.uk/learn-more-about-uk-biobank/news/uk-biobank-launches-one-of-the-largest-scientific-studies Research articles and newsUK Biobank Pharma Proteomics Project Full Cohort Study:  Thermo Fisher Scientific’s Olink Platform Selected for World’s Largest Human Proteome Studyhttps://ir.thermofisher.com/investors/news-events/news/news-details/2025/Thermo-Fisher-Scientifics-Olink-Platform-Selected-for-Worlds-Largest-Human-Proteome-Study/default.aspx Parabiosis Conboy et al (2005) Rejuvenation of aged progenitor cells by exposure to a young systemic environment.  Nature 433: 760-764. https://www.nature.com/articles/nature03260 Villeda et al. (2011). The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature 477, 90–94 https://doi.org/10.1038/nature10357 Organ Aging/Ageing Clock Publications leveraging Olink ProteomicsOh, H.SH et al. (2025). Plasma proteomics links brain and immune system aging with healthspan and longevity. Nat Med 31, 2703–2711. https://doi.org/10.1038/s41591-025-03798-1Goeminne et al (2025). Plasma protein-based organ-specific aging and mortality models unveil diseases as accelerated aging of organismal systems Cell Metabolism, 37, 205-222.e6https://www.cell.com/cell-metabolism/fulltext/S1550-4131(24)00401-7Argentieri, M.A et al. (2024). Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations. Nat Med 30, 2450–2460. https://doi.org/10.1038/s41591-024-03164-7 Young blood factors infused into young miceVilleda et al (2014). Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice.  Nature Medicine.  20:659-663. https://www.nature.com/articles/nm.3569 Single cell work with Stephen QuakePálovics et al (2022). Molecular hallmarks of heterochronic parabiosis at single-cell resolution. Nature 603:309-314. https://www.nature.com/articles/s41586-022-04461-2 Andrew Yang, Gladstone Institute labeling of hundreds of endogenous plasma proteinsYang et al (2020). Physiological blood-brain transport is impaired with age by a shift in transcytosis. Nature 583: 425-430. https://www.nature.com/articles/s41586-020-2453-z Eric Topol episode with Tony on Ground Truthshttps://erictopol.substack.com/p/tony-wyss-coray-the-science-of-aging Mike Snyder’s team (Stanford) and the concept of AgeotypesAhadi S et al. (2020). Personal aging markers and ageotypes revealed by deep longitudinal profiling. Nature Medicine. 2020;26:83–90. https://www.nature.com/articles/s41591-019-0719-5 Preprint ahead of Nature Medicine paper Tony references coming out weeks after podcast episodeDing et al (2026; preprint). Cellular Aging Signatures in the Plasma Proteome Record Human Health and Disease. bioRxiv https://www.biorxiv.org/content/10.64898/2026.02.10.704909v1 Vero Biosciences:  Founded with Tony where a consumer can have blood measured, which organs show accelerated aging with clinician input into potential interventions.  https://www.verobioscience.com/ Teal Rise: Founded with Tony, partnering with Olink that has collected a large database to drive model building across diseases and prediction. https://tealrise.com/ Heike A. Bischoff-Ferrari and the Do-Health Trial:Bischoff-Ferrari et al (2025). Individual and additive effects of vitamin D, omega-3, and exercise on DNA methylation clocks of biological aging in older adults in the Do-Health trial. Nature Aging. 5: 376-385. https://www.nature.com/articles/s43587-024-00793-y Subscribe to the podcast on your favorite player or app:Apple Podcasts: https://apple.co/3T0YbSm Spotify Podcasts: https://open.spotify.com/show/2sZ2wxOqI4b4vSngkajLs8 Amazon Music: https://music.amazon.com/podcasts/d97ace94-f02b-4b37-9532-799548ef2840/proteomics-in-proximity Podcast Addict: https://podcastaddict.com/podcast/proteomics-in-proximity/4098296 Deezer: https://www.deezer.com/us/show/5178787 Proteomics in Proximity refers to the principle underlying Olink technology called the Proximity Extension Assay (PEA). More information about the assay and how it works can be found here: https://bit.ly/3Rt7YiY Host:  Cindy LawleyCo-host: Sarantis ChlamydasExecutive Producer: Cindy LawleyEditor:  Fredrik Hamfelt, PhosworksProject Manager: Eva Kellerman, Phosworks For any questions regarding information Olink Proteomics, please email us at info@olink.com or visit our website: https://www.olink.com/

    53 min
  3. From self-driving cars to self-caring people

    09/09/2025

    From self-driving cars to self-caring people

    Welcome to the Olink® Proteomics in Proximity podcast!    Below are some useful resources mentioned in this episode:    Olink tools and software ·       Olink® Explore HT, Olink’s most advanced solution for high-throughput biomarker discovery, measuring 5400+ proteins simultaneously with a streamlined workflow and industry-leading specificity: https://olink.com/products-services/exploreht/    UK Biobank Pharma Proteomics Project (UKB-PPP), one of the world’s largest scientific studies of blood protein biomarkers conducted to date, https://www.ukbiobank.ac.uk/learn-more-about-uk-biobank/news/uk-biobank-launches-one-of-the-largest-scientific-studies    World Health Organization (2003). Adherence to long-term therapies: evidence for action (PDF).  Geneva: World Health Organisation. ISBN 978-92-4-154599-0   Research articles and news ·       Thermo Fisher Scientific’s Olink Platform Selected for World’s Largest Human Proteome Study https://ir.thermofisher.com/investors/news-events/news/news-details/2025/Thermo-Fisher-Scientifics-Olink-Platform-Selected-for-Worlds-Largest-Human-Proteome-Study/default.aspx ·       Hamilton Se-Hwee Oh et al 2025. Plasma proteomics links brain and immune system aging with healthspan and longevityhttps://www.nature.com/articles/s41591-025-03798-1. Nature Medicine (2025) ·       Song, Y., Abuduaini, B., Yang, X. et al. Identification of inflammatory protein biomarkers for predicting the different subtype of adult with tuberculosis: an Olink proteomic study. Inflamm. Res. 74, 60 (2025). https://doi.org/10.1007/s00011-025-02020-9 ·       Ferhan Qureshi et al 2023. Analytical validation of a multi-protein, serum-based assay for disease activity assessments in multiple sclerosis. Proteomics clinical application 2023 ·       Dhindsa, R.S., Burren, O.S., Sun, B.B. et al. Rare variant associations with plasma protein levels in the UK Biobank. 2023 Nature, DOI: 10.1038/s41586-023-06547-x https://www.nature.com/articles/s41586-023-06547-x ·       Sun, B.B., Chiou, J., Traylor, M. et al.  Plasma proteomic associations with genetics and health in the UK Biobank. 2023 Nature, DOI: 10.1038/s41586-023-06592-6  https://www.nature.com/articles/s41586-023-06592-6  https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehac495/6676779 ·       Eldjarn GH, et al. Large-scale plasma proteomics comparisons through genetics and disease associations. Nature. 2023 Oct;622(7982):348-358. doi: 10.1038/s41586-023-06563-x https://www.nature.com/articles/s41586-023-06563-x#Sec44 ·        Carrasco-Zanini et al 2024 Proteomic prediction of common and rare diseases. https://www.nature.com/articles/s41591-024-03142-z . NatureMedicine volume 30,  pages2489–2498 (2024) ·       Watanabe K, Wilmanski T, Diener C, et al. Multiomic signatures of body mass index identify heterogeneous health phenotypes and responses to a lifestyle intervention.https://www.nature.com/articles/s41591-023-02248-0 ·       Petrera A, von Toerne C, Behlr J, et al. Multiplatform Approach for Plasma Proteomics: Complementarity of Olink Proximity Extension Assay Technology to Mass Spectrometry-Based Protein Profiling. (2020) Journal of Proteome Research,  https://pubs.acs.org/doi/pdf/10.1021/acs.jproteome.0c00641 ·       Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens.  Kardell O, von Toerne C, Merl-Pham J, König AC, Blindert M, Barth TK, Mergner J, Ludwig C, Tüshaus J, Eckert S, Müller SA, Breimann S, Giesbertz P, Bernhardt AM, Schweizer L, Albrecht V, Teupser D, Imhof A, Kuster B, Lichtenthaler SF, Mann M, Cox J, Hauck SM. J Proteome Res. 2024 Jan 5;23(1):117-129. doi: 10.1021/acs.jproteome.3c00473. Epub 2023 Nov 28. PMID: 38015820  https://pubs.acs.org/doi/10.1021/acs.jproteome.3c00473 ·       Wei, S., Shen, R., Lu, X. et al. Integrative multi-omics investigation of sleep apnea: gut microbiome metabolomics, proteomics and phenome-wide association study. Nutr Metab (Lond) 22, 57 (2025). https://doi.org/10.1186/s12986-025-00925-0 ·       Liu, L., Li, M., Qin, Y. et al. Childhood obesity and insulin resistance is correlated with gut microbiome serum protein: an integrated metagenomic and proteomic analysis. Sci Rep 15, 21436 (2025). https://doi.org/10.1038/s41598-025-07357-z ·       Zhang, Xiaotao et al.Modulating a prebiotic food source influences inflammation and immune-regulating gut microbes and metabolites: insights from the BE GONE trial. eBioMedicine, Volume 98, 104873 (2023.).  10.1016/j.ebiom.2023.104873 ·      &nb...

    45 min
  4. A glimpse into product management and PMWC plans with Jenny Samskog

    01/28/2025

    A glimpse into product management and PMWC plans with Jenny Samskog

    Welcome to the Olink® Proteomics in Proximity podcast!   Below are some useful resources mentioned in this episode:    Olink® Reveal, accessible NGS-based proteomics for every lab: https://olink.com/products/olink-reveal Olink tools and software ·       Olink® Explore 3072, the platform utilized by the UK Biobank to measure ~3000 proteins in plasma: https://olink.com/products-services/explore/ ·       Olink® Explore HT, Olink’s most advanced solution for high-throughput biomarker discovery, measuring 5400+ proteins simultaneously with a streamlined workflow and industry-leading specificity: https://olink.com/products-services/exploreht/    UK Biobank Pharma Proteomics Project (UKB-PPP), one of the world’s largest scientific studies of blood protein biomarkers conducted to date, https://www.ukbiobank.ac.uk/learn-more-about-uk-biobank/news/uk-biobank-launches-one-of-the-largest-scientific-studies      Subscribe to the podcast on your favorite player or app: Apple Podcasts: https://apple.co/3T0YbSm    Spotify Podcasts: https://open.spotify.com/show/2sZ2wxO...    Google Podcasts: https://podcasts.google.com/feed/aHR0...    Amazon Music: https://music.amazon.com/podcasts/d97...    Podcast Addict: https://podcastaddict.com/podcast/409...    Deezer: https://www.deezer.com/show/5178787    Player FM: https://player.fm/series/series-3396598    In case you were wondering, Proteomics in Proximity refers to the principle underlying Olink technology called the Proximity Extension Assay (PEA). More information about the assay and how it works can be found here: https://bit.ly/3Rt7YiY   For any questions regarding information Olink Proteomics, please email us ...

    33 min
  5. Proteomics in hundreds of thousands: Prof Sir Rory Collins and Dr Chris Whelan

    01/17/2025

    Proteomics in hundreds of thousands: Prof Sir Rory Collins and Dr Chris Whelan

    Welcome to the Olink® Proteomics in Proximity podcast!    Below are some useful resources mentioned in this episode:    Olink tools and software ·       Olink® Explore 3072, the platform utilized by the UK Biobank to measure ~3000 proteins in plasma: https://olink.com/products-services/explore/ ·       Olink® Explore HT, Olink’s most advanced solution for high-throughput biomarker discovery, measuring 5400+ proteins simultaneously with a streamlined workflow and industry-leading specificity: https://olink.com/products-services/exploreht/    UK Biobank Pharma Proteomics Project (UKB-PPP), one of the world’s largest scientific studies of blood protein biomarkers conducted to date, https://www.ukbiobank.ac.uk/learn-more-about-uk-biobank/news/uk-biobank-launches-one-of-the-largest-scientific-studies    Press release and news story from UK Biobank:https://www.ukbiobank.ac.uk/learn-more-about-uk-biobank/news/launch-of-world-s-most-significant-protein-study-set-to-usher-in-new-understanding-for-medicine   https://www.ukbiobank.ac.uk/learn-more-about-uk-biobank/news/dataset-of-thousands-of-proteins-marks-landmark-step-for-research-into-human-health   https://www.ukbiobank.ac.uk/learn-more-about-uk-biobank/news/uk-biobank-launches-one-of-the-largest-scientific-studies   News stories: Today Programme – Professor Rory Collins live on programme, timestamp 02:36:37   Times – ‘Game-changing’ study of blood proteins will help fight disease Independent – World’s largest proteins study ‘invaluable’ for understanding disease – experts Daily Mail – How Alzheimer's could be diagnosed a DECADE earlier following huge study of blood proteins Mirror – New blood test reveals risk of developing different diseases in 'new frontier of science' Science – Seeking disease insights, UK Biobank launches largest study of human proteinsTechnology Networks – UK Biobank Launches Largest Proteomics Study for Disease Research Chemical and Engineering News – Pharma firms team up to study UK proteomics data   Links to referred episodes:   • Evan – Episode 20:     https://share.transistor.fm/s/f795811e    https://open.spotify.com/episode/6lv5GA8hZCgDvujlBltS9f?si=36a29e6cfa4b4fae     https://podcasts.apple.com/us/podcast/how-proteomics-is-shaping-pharma-strategies/id1645900688?i=1000635040581 • Chris – Episode 16:     https://share.transistor.fm/s/255ad207     https://open.spotify.com/episode/0oe0S6zI8cryUtgZTjGlRq?si=8a7b0323b1364b96     https://podcasts.apple.com/us/podcast/interview-about-the-uk-biobank-with-dr-christopher-whelan/id1645900688?i=1000622521524    Subscribe to the podcast on your favorite player or app: Apple Podcasts: https://apple.co/3T0YbSm    Spotify Podcasts: https://open.spotify.com/show/2sZ2wxO...    Google Podcasts: https://podcasts.google.com/feed/aHR0...    Amazon Music:

    49 min
  6. Decoding Aging and the Environment with Cornelia van Duijn

    11/12/2024

    Decoding Aging and the Environment with Cornelia van Duijn

    Welcome to the Olink® Proteomics in Proximity podcast!  Below are some useful resources mentioned in this episode:    Olink tools and software Olink® Explore 3072, the platform utilized by the UK Biobank to measure ~3000 proteins in plasma: https://olink.com/products-services/explore/ Olink® Explore HT, Olink’s most advanced solution for high-throughput biomarker discovery, measuring 5400+ proteins simultaneously with a streamlined workflow and industry-leading specificity: https://olink.com/products-services/exploreht/    UK Biobank Pharma Proteomics Project (UKB-PPP), one of the world’s largest scientific studies of blood protein biomarkers conducted to date, https://www.ukbiobank.ac.uk/learn-more-about-uk-biobank/news/uk-biobank-launches-one-of-the-largest-scientific-studies    Research articles The support of human genetic evidence for approved drug indications Matthew R Nelson et al,  Nature Genetics 2015 https://www.nature.com/articles/ng.3314   Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations M. Austin Argentieri et al,  Nature Medicine 2024 https://www.nature.com/articles/s41591-024-03164-7   Plasma protein-based organ-specific aging and mortality models unveil diseases as accelerated aging of organismal systems Ludger J.E. Goeminne et al, Cell Metabolism 2024, in press https://www.sciencedirect.com/science/article/abs/pii/S1550413124004017?via%3Dihub   Plasma proteomic associations with genetics and health in the UK Biobank Benjamin B. Sun et, Nature 2023 https://www.nature.com/articles/s41586-023-06592-6   Rare variant associations with plasma protein levels in the UK Biobank Ryan S. Dhindsa; Nature 2023 https://www.nature.com/articles/s41586-023-06547-x   Disease prediction with multi-omics and biomarkers empowers case–control genetic discoveries in the UK Biobank Manik Garg, Nature Genetics, 2024 https://www.nature.com/articles/s41588-024-01898-1   China Kadoorie Biobank: https://www.ckbiobank.org/publications Publications: https://www.ckbiobank.org/publications   Subscribe to the podcast on your favorite player or app: Apple Podcasts: https://apple.co/3T0YbSm   Spotify Podcasts: https://open.spotify.com/show/2sZ2wxO...   Google Podcasts: https://podcasts.google.com/feed/aHR0...    Amazon Music: https://music.amazon.com/podcasts/d97...    Podcast Addict:

    57 min
  7. Complementarity of Mass Spec and PEA

    03/05/2024

    Complementarity of Mass Spec and PEA

    Welcome to the Olink® Proteomics in Proximity podcast!  Below are some useful resources mentioned in this episode:    UK Biobank Pharma Proteomics Project (UKB-PPP), one of the world’s largest scientific studies of blood protein biomarkers conducted to date, https://www.ukbiobank.ac.uk/learn-more-about-uk-biobank/news/uk-biobank-launches-one-of-the-largest-scientific-studies    UKB-PPP online resources developed by Nick Lehner and Maria Wörheide https://metabolomips.org/ukbbpgwas/   Metabolomics and Proteomics Core in Munich: https://www.helmholtz-munich.de/en/core-facility-overview/metabolomics-and-proteomics https://www.helmholtz-munich.de/core-facilities Stefanie.hauck@helmholtz-munich.de  ClinspectM (https://clinspect-m.mscoresys.de/) consortium in the Munich area dedicated to move proteomics forward to clinical application More joint initiatives towards Germany-wide benchmarking and standardized processes are in the making, follow the news on https://www.mscoresys.de/   Research articles Sun, B.B., Chiou, J., Traylor, M. et al.  Plasma proteomic associations with genetics and health in the UK Biobank. 2023 Nature, DOI: 10.1038/s41586-023-06592-6  https://www.nature.com/articles/s41586-023-06592-6 Petrera A, von Toerne C, Behlr J, et al. Multiplatform Approach for Plasma Proteomics: Complementarity of Olink Proximity Extension Assay Technology to Mass Spectrometry-Based Protein Profiling. (2020) Journal of Proteome Research https://pubs.acs.org/doi/pdf/10.1021/acs.jproteome.0c00641 Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens.  Kardell O, von Toerne C, Merl-Pham J, König AC, Blindert M, Barth TK, Mergner J, Ludwig C, Tüshaus J, Eckert S, Müller SA, Breimann S, Giesbertz P, Bernhardt AM, Schweizer L, Albrecht V, Teupser D, Imhof A, Kuster B, Lichtenthaler SF, Mann M, Cox J, Hauck SM. J Proteome Res. 2024 Jan 5;23(1):117-129. doi: 10.1021/acs.jproteome.3c00473. Epub 2023 Nov 28. PMID: 38015820  https://pubs.acs.org/doi/10.1021/acs.jproteome.3c00473   Olink tools and software Olink® Explore 3072, the platform utilized by the UK Biobank to measure ~3000 proteins in plasma: https://olink.com/products-services/explore/ Olink® Explore HT, Olink’s most advanced solution for high-throughput biomarker discovery, measuring 5400+ proteins simultaneously with a streamlined workflow and industry-leading specificity: https://olink.com/products-services/exploreht/    Subscribe to the podcast on your favorite player or app: Apple Podcasts: https://apple.co/3T0YbSm   Spotify Podcasts: https://open.spotify.com/show/2sZ2wxO...    Google Podcasts: https://podcasts.google.com/feed/aHR0...   Amazon Music:

    48 min
  8. How proteomics is shaping pharma strategies

    11/16/2023

    How proteomics is shaping pharma strategies

    Welcome to the Olink® Proteomics in Proximity podcast! Below are some useful resources mentioned in this episode: Olink tools and software• Olink® Explore 3072, the platform utilized by the UK Biobank to measure ~3000 proteins in plasma: https://olink.com/products-services/explore/• Olink® Explore HT, Olink’s most advanced solution for high-throughput biomarker discovery, measuring 5400+ proteins simultaneously with a streamlined workflow and industry-leading specificity: https://olink.com/products-services/exploreht/ UK Biobank Pharma Proteomics Project (UKB-PPP), one of the world’s largest scientific studies of blood protein biomarkers conducted to date, https://www.ukbiobank.ac.uk/learn-more-about-uk-biobank/news/uk-biobank-launches-one-of-the-largest-scientific-studies Research articles• Dhindsa, R.S., Burren, O.S., Sun, B.B. et al. Rare variant associations with plasma protein levels in the UK Biobank. 2023 Nature, DOI: 10.1038/s41586-023-06547-xhttps://www.nature.com/articles/s41586-023-06547-x• Sun, B.B., Chiou, J., Traylor, M. et al.  Plasma proteomic associations with genetics and health in the UK Biobank. 2023 Nature, DOI: 10.1038/s41586-023-06592-6 https://www.nature.com/articles/s41586-023-06592-6• Ticau S, Sridharan G, Tsour S, et al. Neurofilament Light Chain as a Biomarker of Hereditary Transthyretin-Mediated Amyloidosis 2021 Neurology, DOI: 10.1212/WNL.0000000000011090https://n.neurology.org/content/96/3/e412.long• Zannad F, Ferreira JP, Butler J, et al.  Effect of Empagliflozin on Circulating Proteomics in Heart Failure: Mechanistic Insights from the EMPEROR Program. 2022 European Heart Journal, DOI: 10.1093/eurheartj/ehac495                https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehac495/6676779• Eldjarn GH, et al. Large-scale plasma proteomics comparisons through genetics and disease associations. Nature. 2023 Oct;622(7982):348-358. doi: 10.1038/s41586-023-06563-xhttps://www.nature.com/articles/s41586-023-06563-x#Sec44• [PREPRINT] Carrasco-Zanini et al 2023 Proteomic prediction of common and rare diseases MedRxiv https://www.medrxiv.org/content/10.1101/2023.07.18.23292811v1• Michaëlsson E, Lund LH, Hage C, et al. Myeloperoxidase Inhibition Reverses Biomarker Profiles Associated With Clinical Outcomes in HFpEF. 2023 JACC. Heart Failure, DOI: 10.1016/j.jchf.2023.03.002https://www.sciencedirect.com/science/article/pii/S2213177923001257• Girerd N, Levy D, Duarte K, et al.  Protein Biomarkers of New-Onset Heart Failure: Insights From the Heart Omics and Ageing Cohort, the Atherosclerosis Risk in Communities Study, and the Framingham Heart Study. 2023 Circulation Heart Failure, DOI: 10.1161/CIRCHEARTFAILURE.122.009694https://www.ahajournals.org/doi/abs/10.1161/CIRCHEARTFAILURE.122.009694 Subscribe to the podcast on your favorite player or app:Apple Podcasts: https://apple.co/3T0YbSm Spotify Podcasts: https://open.spotify.com/show/2sZ2wxO... Google Podcasts: https://podcasts.google.com/feed/aHR0... Amazon Music: https://music.amazon.com/podcasts/d97... Podcast Addict: https://podcastaddict.com/podcast/409... Deezer: https://www.deezer.com/show/5178787 Player FM: https://player.fm/series/series-3396598 In case you were wondering, Proteomics in Proximity refers to the principle underlying Olink technology called the Proximity Extension Assay (PEA). More information about the assay and how it works can be found here: https://bit.ly/3Rt7YiY For any questions regarding information about Olink Proteomics, please email us at info@olink.com or visit our website: https://www.olink.com/ Interested in a specific podcast topic or guest? Reach out to us at PIP@olink.com WHAT IS PROTEOMICS IN PROXIMITY?Proteomics in Proximity discusses the intersection of proteomics with genomics for drug target discovery, the application of proteomics to reveal disease biomarkers, and current trends in using proteomics to unlock biological mechanisms. Co-hosted by Olink's Cindy Lawley and Sarantis Chlamydas.

    44 min
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Proteomics in Proximity discusses the intersection of proteomics with genomics for drug target discovery, the application of proteomics to reveal disease biomarkers, and current trends in using proteomics to unlock biological mechanisms. Co-hosted by Olink's Dale Yuzuki, Cindy Lawley and Sarantis Chlamydas.

Information

  • Creator
    Olink Proteomics
  • Years Active
    2022 - 2026
  • Episodes
    28
  • Rating
    Clean
  • Copyright
    © Olink Proteomics
  • Show Website
    Proteomics in Proximity

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