Going anti-Viral

Going Anti-Viral

Introducing Going anti-Viral, the podcast of the IAS–USA, a professional continuing medical education organization focused on HIV and other viral diseases. I’m Dr Michael Saag, professor emeritus of medicine and infectious diseases at the University of Alabama at Birmingham and volunteer member of the IAS–USA Board of Directors.  Join us as we interview experts in viral medicine about their area of specialty and current developments in the field. Other episodes are drawn from the IAS-USA vast catalogue of panel discussions, Dialogues, and various meetings and conferences.  Going anti-Viral is a podcast series for clinicians, produced by the International Antiviral Society–USA. The IAS–USA is a not-for-profit professional organization committed to improving the treatment, care, and quality of life for people with or at risk for HIV or other viral infections and their complications through balanced education and information. This podcast is intended as a clinical source of information for specialists in this field, but we hope anyone listening will enjoy learning more about the state of modern medicine around viral infections and their consequences.

  1. 2d ago

    TMVII: Understanding the Emergence of Trichophyton mentagrophytes Genotype VII – Dr Jason Zucker

    In episode 80 of Going anti-Viral, Dr Jason Zucker joins host Dr Michael Saag to provide an update on the Trichophyton mentagrophytes genotype VII (TMVII) infection. Dr Zucker is an Assistant Professor of Medicine at Columbia University and Assistant Medical Director of the New York City STD Prevention Training Center. Dr Zucker is an experienced HIV, HIV prevention, and sexual health care provider providing status-neutral care to patients of all ages in New York. His research focuses on the intersection of data science, behavioral science, and implementation science. Dr Zucker discusses the emerging dermatophyte infection TMVII, its transmission, clinical presentation, and diagnosis. Dr Zucker and Dr Saag also detail treatment strategies, emphasizing the significance in sexual health and STI management. 0:00 – Introduction  1:21 – Background, epidemiology and transmission  5:58 – Clinical presentation and diagnosis  9:18 – Treatment protocols for TMVII 11:32 – Challenges and considerations in management of TMVII 15:38 – Future outlook and final thoughts  Resources:  Morbidity and Mortality Weekly Report (MMWR) - Notes from the Field: Trichophyton mentagrophytes Genotype VII — New York City, April–July 2024 https://www.cdc.gov/mmwr/volumes/73/wr/mm7343a5.htm Going anti-Viral: Episode 30 - Update on Mpox - a Public Health Emergency - Dr Jason Zucker YouTube:  https://youtu.be/GTwXSvkcJ74  Apple Podcasts:  https://podcasts.apple.com/us/podcast/episode-30-update-on-mpox-a-public-health-emergency/id1713226144?i=1000675771251  __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube X Facebook Instagram ...

    20 min
  2. 6d ago

    Special Episode - Latest Update on Emerging Infections and Health Threats

    In episode 79 of Going anti-Viral, we represent a panel discussion from June 9, 2026, as part of the IAS–USA Dialogue series Emerging Infections and Health Threats. This Dialogue is a must listen as our distinguished panel of infectious disease experts dives deep into some of the most pressing public health challenges facing the world today. Moderated by Carlos del Rio, MD, a Distinguished Professor of Medicine in the Division of Infectious Diseases at Emory University School of Medicine, this Dialogue brings together world-class experts Yvonne Maldonado, MD of Stanford University, and Peter Chin-Hong, MD, of the University of California San Francisco. The panel discusses the impact of the World Cup on public health as well as providing updates on current health threats including hantavirus, Ebola, measles, alpha-gal syndrome, and influenza. The panel also provides an update on alpha-gal syndrome and tick-borne diseases, as well as a discussion about an effort by Google to control diseases spread by mosquitoes. Finally, the panelists discuss the risk of the New World screwworm fly to livestock and humans, an outbreak of Campylobacter from the consumption of raw milk, and the impact of the World Cup on influenza in the US. 0:00 – Introduction  1:32 – Impact of the World Cup travel on public health 7:10 – Lessons learned from the hantavirus outbreak  13:42 – Status of Ebola outbreak, treatment options, and vaccine development 25:18 – Update on measles in the US and public health response 37:22 – Overview of alpha-gal syndrome and tick-borne diseases 42:20 – Update on the Google Debug project 45:31 – Risk of the New World screwworm fly to livestock and humans  47:42 – Outbreak of Campylobacter from the consumption of raw milk 52:59 – Overview of influenza season in southern hemisphere and risk to the US 57:46 – Closing remarks  __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube X Facebook Instagram ...

    1h 2m
  3. Jun 2

    From Data to Guidance: The Process Behind Clinical Guidelines – Dr Rajesh Gandhi

    In episode 78 of Going anti-Viral, Dr Rajesh T. Gandhi joins host Dr Michael Saag to discuss the process of guidelines development. Dr Gandhi is a Professor of Medicine at Harvard Medical School and Principal Investigator and Co-Director of the Harvard University Center for AIDS Research (CFAR). Dr Gandhi is the Vice-Chair of the ACTG, Vice-Chair of the Infectious Diseases Society of America COVID-19 Treatment Guidelines Panel, Chair of the International Antiviral Society-USA Panel on Antiretroviral Drugs for Treatment and Prevention of HIV in Adults, and the Lead Editor for Infectious Diseases, NEJM Clinician. Dr Gandhi and Dr Saag explore the intricate process of developing HIV treatment guidelines, including evidence review, panel selection, and updates on new topics like transgender care and substance use disorders. They discuss how guidelines are created, their impact on clinical practice, and future directions in HIV care. 0:00 – Introduction  1:54 – The purpose and impact of guidelines 4:00 – Panel composition and selection process 6:00 – Guideline structure and key updates 12:34 – Emerging topics: transgender care and transplant medicine 14:31 – Substance use disorders and treatment innovations 16:03 – Evidence-based recommendations and their strength 22:07 – Guidelines development process and team dynamics 24:42 – Living guidelines versus published documents 28:41 – Closing thoughts and future directions Resources:  Going-anti-Viral: Episode 32 - Update on the New Antiretroviral Therapy Guidelines - Dr Rajesh Gandhi YouTube:  https://youtu.be/G7FQTInz-dY  Apple Podcasts:  https://podcasts.apple.com/us/podcast/episode-32-update-on-the-new-antiretroviral-therapy/id1713226144?i=1000678818027  __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube X Facebook Instagram ...

    31 min
  4. May 19

    Management of Hepatitis B Virus Infection and Vaccination – Dr Debika Bhattacharya

    In episode 77 of Going anti-Viral, Dr Debika Bhattacharya joins host Dr Michael Saag to discuss the management of hepatitis B virus (HBV) infection and vaccination. Dr Bhattacharya is a Clinical Professor at the University of California Los Angeles (UCLA) David Geffen School of Medicine and specializes in the management of HIV and HIV/viral hepatitis coinfection and sees patients with viral hepatitis and HIV/viral hepatitis coinfection at UCLA and its affiliated clinics. Her research involves viral hepatitis clinical therapeutics and long-term clinical outcomes in persons with HIV/viral hepatitis or viral hepatitis alone. Dr Saag and Dr Bhattacharya discuss HBV infection and vaccination, especially among people with HIV addressing prevalence, serology interpretation, vaccination strategies, and management of hepatitis B in the context of HIV treatment. They also reinforce the need for more research into therapies that will lead to a cure for hepatitis B.  0:00 – Introduction  1:16 – Understanding hepatitis B and its impact on people with HIV   2:56 – Vaccination strategies for hepatitis B  4:53 – Interpreting hepatitis B serology results  8:38 – Vaccination protocols and recommendations  13:19 – Managing patients with hepatitis B  14:29 – Long-acting therapies and hepatitis B risks  17:29 – Screening and monitoring for hepatitis B  19:01 – Navigating core antibody positivity  23:36 – The importance of antibody titers  28:23 – Final thoughts on hepatitis B management  Resources:  Going-anti-Viral: Episode 31 - Will we ever have a cure for hepatitis B? - Dr Kenneth Sherman YouTube:  https://youtu.be/yh48RFOrISk  Apple Podcasts:  https://podcasts.apple.com/us/podcast/episode-31-will-we-ever-have-a-cure-for-hepatitis-b/id1713226144?i=1000677466892  __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube X Facebook Instagram ...

    33 min
  5. May 5

    The Impact of Long-acting Injectable HIV Treatments on Public Health – Dr Kelly Gebo

    In episode 76 of Going anti-Viral, Dr Kelly Gebo joins host Dr Michael Saag to discuss the impact of long-acting injectable HIV treatments on public health. Dr Gebo is Dean of the Milken Institute School of Public Health at the George Washington University. An infectious disease physician-scientist, educator, and accomplished academic leader, Dr Gebo’s work focuses on health equity, access to care, and outcomes for people affected by infectious diseases such as HIV, COVID-19, and Mpox. Dr Gebo and Dr Saag discuss the current state of HIV epidemiology, the promise of long-acting injectables, and strategies to improve access and prevention efforts. Dr Saag and Dr Gebo also emphasize that advocacy is needed to expand access to long-acting injectable HIV treatments to reach at-risk populations. 0:00 – Introduction  1:30 – Current epidemiology of HIV: a global and US perspective 3:25 – Barriers to HIV screening and treatment 6:27 – Exploring PrEP and long-acting injectables 8:56 – Reaching at-risk populations for HIV prevention 11:33 – Insurance coverage and access to HIV prevention 13:59 – The role of primary care in HIV prevention 16:27 – Advocacy for policy changes in HIV prevention 23:53 – Implementation science and future directions Resources:  The George Washington University Milken Institute School of Public Health https://publichealth.gwu.edu/  __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube X Facebook Instagram ...

    27 min
  6. Apr 21

    Cognitive Aging in HIV: Clinical Assessment and Management – Dr Shibani Mukerji

    In episode 75 of Going anti-Viral, Dr Shibani Mukerji joins host Dr Michael Saag to discuss a presentation she gave at the 2026 Conference on Retroviruses and Opportunistic Infections (CROI) entitled Cognitive Aging in HIV: Clinical Assessment and Management. Dr Mukerji is an Associate Professor of Neurology at Harvard Medical School and is a practicing neurologist in the Department of Neurology and Division of Infectious Diseases at Massachusetts General Hospital. Her research focuses on HIV pathogenesis in the central nervous system and her clinical focus is neurology-infectious diseases, with specific interests in neurological complications and aging in people living with HIV. Dr Mukerji shares her journey in neurology, her research on HIV and neurological complications, and insights into brain health in aging populations, especially those with HIV. Dr Mukerji and Dr Saag offer practical approaches to cognitive assessment, sleep, mood, and movement issues, emphasizing a longitudinal, patient-centered model of care.  0:00 – Introduction  2:07 – Dr Mukerji 's journey in neurology and infectious diseases 7:39 – Cognitive aging in HIV: clinical assessment and management 13:26 – Understanding cognitive health in HIV patients 18:29 – Assessment and management of depression, sleep, and movement disorders  26:26 – Impact of hearing loss and emotional health on cognitive impairment 31:15 – The Valcour tripod: cognitive, motor, and mood assessment 34:15 – Future directions in HIV and neurology research Resources:  CROI 2026: https://www.croiconference.org/ View Dr Mukerji 's presentation at CROI 2026: https://www.croiwebcasts.org/p/2026croi/croi/20  View Presentation by Dr Victor Valcour at CROI 2019: https://www.croiwebcasts.org/p/2019croi/159  __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube X Facebook Instagram ...

    37 min
  7. Apr 7

    Immunology of HIV Cure and Beyond: Navigating Immunology Presentations at CROI 2026 – Dr John Frater

    In episode 74 of Going anti-Viral, Dr John Frater joins host Dr Michael Saag to discuss a presentation he gave at the 2026 Conference on Retroviruses and Opportunistic Infections (CROI) entitled Immunology of HIV Cure and Beyond: Navigating Immunology Presentations at CROI 2026.  Dr Frater is a Professor of Infectious Diseases at the University of Oxford where he leads the HIV Reservoir and Cure Group. The aim of his research is to explore strategies for targeting the reservoir of latent HIV infection in treated individuals, with a specific interest in primary HIV infection. He is a lead investigator on several major HIV clinical studies, many of which include antiretroviral therapy treatment interruptions. His laboratory focus is on immune responses that may lead to viral control and the impact of viral variation. Dr Frater and Dr Saag discuss the basics of HIV infection and antiretroviral therapy as well as the barriers to HIV cure. They also address complexities of HIV latency and the challenges in identifying and eliminating latent reservoirs. Dr Frater addresses the promising strategies involving immune responses in targeting reservoirs and the role of early treatment in HIV cure.   0:00 – Introduction  2:15 – Basics of HIV infection and the barrier to HIV cure: latently infected cells 3:56 – Why do some cells die after 1 day 6:04 – Strategies to identify and eliminate latently infected cells 8:52 – The role of immune responses in targeting reservoirs 11:42 – Timing of reservoir establishment and early treatment  16:49 – Measuring the latent reservoir: challenges and methods 18:16 – The London Patient and cure evidence 22:14 – Future directions and hope for HIV cure Resources:  CROI 2026: https://www.croiconference.org/  View Dr Frater’s presentation at CROI 2026: https://www.croiwebcasts.org/p/2026croi/croi/CR-55003  __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube X Facebook Instagram ...

    28 min
  8. Apr 1

    Special Episode - Latest Update on Emerging Infections and Health Threats

    In episode 73 of Going anti-Viral, we represent a panel discussion from March 26, 2026, as part of the IAS–USA Dialogue series Emerging Infections and Health Threats. This Dialogue is a must listen as our distinguished panel of infectious disease experts dives deep into some of the most pressing public health challenges facing the world today. Moderated by Carlos del Rio, MD, a Distinguished Professor of Medicine in the Division of Infectious Diseases at Emory University School of Medicine, this Dialogue brings together world-class experts Yvonne Maldonado, MD, and Peter Chin-Hong, MD. The panel discusses a recent federal court ruling regarding the Advisory Committee on Immunization Practices (ACIP) and addresses the latest news on rates of vaccination and an update on emerging viral outbreaks, including measles, influenza, COVID-19, meningitis, tuberculosis, mpox, and RSV. The panel also reflects on the implications of the lack of leadership at the CDC on public health. 0:00 – Introduction  2:33 – March 2026 federal court ruling pausing the work of the ACIP 7:08 – Review of the reduction in immunization rates in the US 12:51 – Measles cases in the US and efforts to address misinformation 20:28 – Breaking down recent influenza rates  25:42 – Update on COVID-19 – variants and vaccination 33:42 – Leadership gap at the CDC and implications for public health  41:35 – Meningitis outbreak in England and status of vaccination in the US 49:46 – Increase in cases of tuberculosis in the US 56:45 – Update on mpox cases and vaccination 59:12 – Brief review of RSV cases and vaccination and closing remarks  __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube X Facebook Instagram ...

    1h 4m

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About

Introducing Going anti-Viral, the podcast of the IAS–USA, a professional continuing medical education organization focused on HIV and other viral diseases. I’m Dr Michael Saag, professor emeritus of medicine and infectious diseases at the University of Alabama at Birmingham and volunteer member of the IAS–USA Board of Directors.  Join us as we interview experts in viral medicine about their area of specialty and current developments in the field. Other episodes are drawn from the IAS-USA vast catalogue of panel discussions, Dialogues, and various meetings and conferences.  Going anti-Viral is a podcast series for clinicians, produced by the International Antiviral Society–USA. The IAS–USA is a not-for-profit professional organization committed to improving the treatment, care, and quality of life for people with or at risk for HIV or other viral infections and their complications through balanced education and information. This podcast is intended as a clinical source of information for specialists in this field, but we hope anyone listening will enjoy learning more about the state of modern medicine around viral infections and their consequences.

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