Skinside Out

Welcome to Skinside Out, where science meets beauty, the ultimate dermatology podcast! Dive deep into the fascinating world of skin health with expert insights, evidence-based discussions, and myth-busting truths. Each episode explores the medical, cosmetic, and surgical aspects of dermatology, while keeping you informed about trending skincare topics. Whether you’re a skincare enthusiast, medical professional, or just curious about how to achieve your best skin, Skinside Out is your go-to resource for staying informed and inspired.

  1. 5d ago

    Peptides: Oral and Injectable

    Peptides are everywhere, but how much do we actually know about the oral and injectable versions? Dr. Zain and Courtney continue their peptide conversation by exploring collagen supplements, GHK Copper, BPC 157, ipamorelin, and CJC 1295. They discuss what the current evidence shows, where research is still limited, and why the way a peptide is sourced and delivered matters. The conversation also covers hormone related peptides, potential risks, FDA approval, compounded products, online pharmacies, and the importance of working with a physician instead of self medicating. Dr. Zain and Courtney also break down the difference between established, emerging, and investigational treatments and explain how they evaluate peptides based on their intended goal, supporting evidence, method of administration, and known and unknown risks. They finish by discussing marketing claims surrounding aging and longevity and why improving healthspan may be more meaningful than simply extending lifespan. 00:00 Introduction to oral and injectable peptides01:00 Collagen peptides and the evidence03:00 GHK Copper05:00 BPC 157 and tissue repair06:00 Ipamorelin and CJC 129507:00 Hormones and potential health risks09:00 FDA approval and experimental peptides11:00 Understanding the evidence ladder13:00 Evaluating peptide marketing claims15:00 Healthspan versus lifespan16:00 Questions clinicians should ask about peptides18:00 Where peptides could fit into future healthcare20:00 Balancing innovation with patient safety22:00 Taking a closer look before using peptides

  2. Sep 28

    Peptides, Growth Factors, and Exosomes

    Peptides, growth factors, and exosomes are becoming some of the biggest buzzwords in skincare, but what do they actually do? Dr. Zain and Courtney break down the differences between these powerful molecules, how they communicate with skin cells, where they come from, and what the current clinical data tells us. The conversation covers collagen supporting peptides, growth factors involved in wound healing and tissue repair, and exosomes as a delivery system for different signaling molecules. They also discuss sourcing, the importance of clinical testing, PDRN, and why the formulation and stability of these ingredients matter. Dr. Zain and Courtney also share some of their favorite products, including SkinMedica TNS, Neocutis, Revision, and Nectifirm. They explain how procedures such as microneedling, RF microneedling, and lasers can enhance the delivery of these ingredients into the skin, and why combining different products may help maximize results. The episode wraps up with a discussion about the importance of looking critically at skincare claims and relying on meaningful clinical data rather than marketing alone. 00:00 Introduction to peptides01:00 How peptides work with skin cells02:00 Growth factors and cellular signaling03:00 What are exosomes?04:00 What peptides can do05:00 Where peptides come from07:00 Clinical data on peptides08:00 Understanding growth factors10:00 Clinical evidence for growth factors11:00 Favorite growth factor products12:00 Introduction to exosomes14:00 Why exosomes are so delicate15:00 Human derived vs plant derived exosomes17:00 PDRN and emerging skincare ingredients19:00 Exosomes vs growth factors20:00 What the clinical evidence says21:00 Enhancing skincare delivery22:00 Combining peptides, growth factors, and exosomes24:00 Why clinical data matters25:00 Looking ahead in skincare

  3. Sep 21

    Skin, Metabolism & Longevity

    Skin Side Out Episode 70 explores the connection between skin health, metabolism, aging, and longevity. Dr. Zain, Heather, and Courtney discuss how dermatology is moving toward a more comprehensive approach that considers what is happening inside the body, not just what appears on the skin. The conversation covers regenerative medicine, collagen, GLP 1 medications, muscle loss, metabolic health, inflammation, lab testing, and how changes in the body can show up through the skin. They also discuss the importance of working with a primary care physician, being cautious with emerging treatments such as peptides and exosomes, and understanding the difference between promising treatments and those backed by strong evidence. The episode wraps up with five pillars of healthy aging: sun protection, preserving muscle and bone, optimizing metabolic health, reducing inflammation and environmental damage, and using aesthetic treatments thoughtfully. They also emphasize sleep, mental health, healthy routines, and focusing on becoming the best version of yourself rather than trying to look like someone else. 00:00 Skin, metabolism, and longevity01:00 Understanding aging and the future of aesthetics02:00 Taking a whole body approach to dermatology05:00 Optimizing health before illness06:00 What regenerative medicine means07:00 Stimulating collagen and improving skin health09:00 Regenerative medicine and PRP10:00 What the skin can reveal about internal health13:00 A skin finding that revealed severe metabolic problems15:00 The importance of primary care16:00 How aging affects collagen, muscle, bone, and volume18:00 GLP 1 medications and muscle loss20:00 Metabolic health and longevity23:00 The importance of tracking health markers over time25:00 Looking beyond standard lab testing28:00 Challenges within the healthcare system29:00 The controversy surrounding regenerative treatments31:00 Understanding evidence, safety, and experimental treatments33:00 Researching products and understanding what is actually being used34:00 The future of dermatology36:00 Personalized and integrated care37:00 The five pillars of healthy aging38:00 Preserving muscle and bone39:00 Metabolic health, inflammation, and sleep41:00 Using aesthetic treatments thoughtfully42:00 Mental health and overall wellbeing44:00 Small habits that can improve daily life46:00 The future of longevity care47:00 Launching a longevity program at Noor Dermatology Aesthetics48:00 Closing thoughts

  4. Sep 7

    Optimize Your Upcoming Fall Treatments

    Optimizing Fall Skin Treatments: Retinoids, Brightening Agents, Rosacea Care & Collagen Boosters | Skinside Out Dr. Zain hosts Skinside Out with Heather and Courtney to discuss optimizing skincare and pre-treatments for fall procedures as weather shifts cooler and drier. They recommend a solid baseline regimen (vitamin C, retinoids, sunscreen) and adjuncts like growth factors, exosomes, and peptides to support recovery and collagen. For pigment concerns after summer sun, they cover hydroquinone (with breaks and dermatologist guidance), tranexamic acid, arbutin, kojic acid, azelaic acid, glycolic acid, and retinoids, plus options like oral tranexamic acid, glutathione, and antioxidant supplements including Inner Glow Age Defense with polypodium leucotomos. Sunscreen is emphasized, including Isdin Eryfotona Actinica. For redness/rosacea, they review sulfur products, ivermectin, azelaic acid, metronidazole, Rhofade for events, lasers (IPL, DermaV), and doxycycline. For texture and laxity, they highlight growth factor serums, ReQ, Plated, and exosomes, and discuss gentle peels (mandelic, glycolic) and PRX peel as low-downtime collagen stimulators, with guidance on pausing actives around procedures. 00:00 Fall Treatment Game Plan00:23 Skincare Basics for Prep01:29 Biostimulators and Recovery Boosters02:31 Targeting Pigment After Summer05:08 Pre Treatments and Timing Tips08:56 Supplements and Sunscreen Essentials10:47 Redness and Rosacea Strategies13:13 Peels Without the Fear14:20 Laxity Texture and Collagen Support16:36 Wrap Up and Where to Follow

  5. Aug 31

    Rate the Rave: Trendy Skincare Reviews

    In this “Rate the Rave” episode of Skinside Out, Dr. Zain Hussain with Heather and Courtney score trendy skincare products from 1–10 and explain why. They rate snail mucin low as a nonessential hydrator, pimple patches as helpful mainly for preventing picking (with irritation risks from added actives), and Differin Gel as an accessible, tolerable starter acne treatment for teens. Medicube Pink PDRN Serum scores near zero due to concerns about buzzword marketing and unclear sourcing/amounts of PDRN. St. Ives Apricot Scrub is strongly discouraged for irritation and barrier damage. Hypochlorous spray rates high for gentle antimicrobial/anti-inflammatory use, while opinions vary on The Ordinary and SkinCeuticals C E Ferulic (cost, smell, irritation, oxidation). La Mer is rated low due to price, TNS Advanced Serum is moderately recommended, CeraVe Hydrating Cleanser is disliked, Vanicream is highly favored for gentleness, beef tallow is rejected, nose strips are rated poorly, slugging gets mixed reviews, and sunscreen is rated 10/10 with favorite picks shared. 00:00 Show Intro 00:11 Rate the Rave Rules 00:32 Snail Mucin Hype 02:07 Pimple Patch Pros 04:12 Differin Gel Debate 05:17 PDRN Serum Buzzword 07:05 Apricot Scrub Warning 09:07 Hypochlorous Spray Win 09:47 The Ordinary Rundown 10:45 CE Ferulic Reality Check 13:49 La Mer Teaser 14:04 Luxury Cream Price Debate 14:52 TNS Serum Ratings 15:46 CeraVe Cleanser Critique 16:42 Vanicream Fan Favorites 18:03 Beef Tallow Backlash 21:17 Nose Strips Reality Check 22:22 Slugging Pros and Cons 24:37 Sunscreen Must Have 25:02 Favorite Sunscreens Picks 26:42 Wrap Up and Outro

5
out of 5
6 Ratings

About

Welcome to Skinside Out, where science meets beauty, the ultimate dermatology podcast! Dive deep into the fascinating world of skin health with expert insights, evidence-based discussions, and myth-busting truths. Each episode explores the medical, cosmetic, and surgical aspects of dermatology, while keeping you informed about trending skincare topics. Whether you’re a skincare enthusiast, medical professional, or just curious about how to achieve your best skin, Skinside Out is your go-to resource for staying informed and inspired.

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