Alzheimer’s Breakthrough with Dr. Josh Helman, MD

Dr. Josh Helman, MD

Welcome to Alzheimer’s Breakthrough with Dr. Josh Helman, MD, the transformative podcast that delves into the root causes of cognitive decline and provides real solutions for preventing—and even reversing—Alzheimer’s. Hosted by Dr. Josh Helman, MD, a Harvard-trained physician with advanced degrees in biochemistry, this show is designed for individuals living with Alzheimer’s, their loved ones, and anyone determined to preserve and improve brain health. Each week, Dr. Josh demystifies the complexities of dementia, unpacks the latest breakthroughs in neurodegenerative research, and shares actionable lifestyle strategies drawn from his six years of clinical experience reversing Alzheimer’s. From tackling nutritional deficiencies and toxin exposure to exploring cutting-edge diagnostics and mind-body interventions, Alzheimer’s Breakthrough with Dr. Josh Helman, MD, turns every challenge into an opportunity to reclaim cognitive vitality and hope. If you’re ready to discover evidence-based approaches that can restore mental clarity and empower you or your loved ones, tune in to Alzheimer’s Breakthrough with Dr. Josh Helman, MD, on Spotify, Apple Podcasts, or YouTube. Get ready to embrace a brighter future—one breakthrough at a time.

  1. 1D AGO

    Can a Plant-Based Diet Prevent Alzheimer’s? Dr. Michael Greger Explains the Science

    Did you know that populations that primarily eat plant-based diets have dramatically lower rates of dementia? In this episode, Dr. Michael Greger, a renowned physician and author, shares groundbreaking research on how nutrition, particularly plant-based diets, affects Alzheimer's prevention. We examine the science behind heart-healthy, brain-boosting foods, emphasizing the importance of a whole-food, plant-based diet for overall well-being. You’ll learn how simple dietary changes can alter the course of cognitive health and how the latest studies are reshaping our understanding of brain aging. Whether you’re looking to prevent Alzheimer’s or simply optimize your brain health, Dr. Greger offers actionable advice supported by decades of research. Tune in to discover how small changes in your diet can have a profound impact on your cognitive function and longevity. “Alzheimer's is related to the atherosclerotic buildup of plaque inside the intracranial arteries in the brain. So the same dietary changes that can help with cardiovascular health can also help with cognitive health. In other words, what's good for the heart is good for the head.” ~ Dr. Michael Greger, M.D. FACLM In this Episode 00:00 - Introduction to Dr. Michael Greger 02:28 - The importance of lifestyle for brain health 04:50 - How heart-healthy diets support brain health 06:40 - Practical tips for adopting a plant-based diet wherever you are 10:00 - The ketogenic diet debate 14:27 - How pollutants affect brain health 16:46 - The link between diabetes and Alzheimer's 22:04 - Dr. Greger's thoughts on lab testing 24:28 - Debunking common myths about plant-based eating 28:07 - How to stick to healthy habits 29:59 - Is fasting good for cognitive health? Resources: - Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide - How Not to Age by Dr. Michael Greger - https://nutritionfacts.org/book/how-not-to-age/ Connect with Dr. Michael Greger, M.D. FACLM: - Website - https://drgreger.org/ - Instagram - https://www.instagram.com/nutrition_facts_org/ - YouTube - https://www.youtube.com/@NutritionFactsOrg Connect with Dr. Josh Helman, MD: - Instagram - https://www.instagram.com/greenbrainsMD - Facebook - https://www.facebook.com/greenbrainsmd/ - a href="https://www.linkedin.com/in/doctorjosh" rel="noopener noreferrer"...

    32 min
  2. JAN 8

    Parasites, Toxins, and Alzheimer’s: Dr. Josh Helman’s Q&A Episode

    Do you have a brain health question you are afraid to ask? In this special Q&A episode, I’m answering the most pressing questions I receive about brain health, Alzheimer’s prevention, spike protein exposure, detoxification, parasites, fasting, and longevity. These are complex, often controversial topics, and my goal is to cut through fear, misinformation, and oversimplified advice with evidence-based clarity and real-world clinical experience. I explain what we currently know about spike proteins and what safe, physician-guided detoxification actually looks like. We explore glutathione as a foundational detox molecule, why overaggressively breaking down biofilms can backfire, and how lifestyle interventions can improve brain resilience even when damage has already occurred. This episode also dives into parasites, heavy metals, mold toxins, and how to separate legitimate detox science from marketing hype. I answer practical questions about fasting, antioxidants, supplements, affordability, and what truly moves the needle for protecting your brain long term. Most importantly, I want you to leave this conversation with hope. There is no single magic fix—but there is a powerful toolbox that can improve brain health, slow decline, and in many cases, support meaningful recovery. “You do not need lots of expensive boutique tests and exotic supplements to meaningfully protect your brain. Diet, exercise, cognitive training, and vascular risk management using low-tech components definitely improve cognition.” ~ Dr. Josh Helman In this Episode 00:00 - Introduction 00:51 - How can we detox spike proteins from the body? 07:35 - What are some things we can do to fix the damage from spike proteins? 09:24 - Why doesn't the spike protein affect everyone the same way? 26:18 - How can someone get mercury poisoning from a root canal? 27:52 - Are parasites really as widespread, or are the stories exaggerated? 34:51 - What is the difference between GLP-1 and human growth hormone receptors? 36:33 - How does fasting help prevent Alzheimer's, and what's the safest way to do it? 41:40 - How can the average person afford the expensive tests and supplements? 43:27 - What are the most affordable practical steps to protect brain health? 45:15 - How can listeners get reliable guidance without needing a consultation 52:25 - Can dogs get dementia or Alzheimer's, and can it be reversed? 54:37 - What do I personally do to improve my brain health and prevent decline? Resources: - Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide - Get reliable supplements at Dr. Josh Helman's Dispensary - https://drjosh.com/fullscript - Dr. Josh’s Favorite Products - https://drjosh.com/products/ Connect with Dr. Josh Helman, MD: - Instagram - a...

    1h 1m
  3. JAN 1

    Nutritional Secrets That May Help Prevent Alzheimer’s With Dr. Steve Blake

    Did you know the right combination of food, as well as vitamins and minerals, can potentially protect your brain from Alzheimer's? Today's guest reveals the science behind nutrition and brain health. In today’s episode, Dr. Steve Blake, an expert in nutritional neuroscience, joins me to discuss how specific vitamins, minerals, and omega-3 fatty acids play a crucial role in brain health and Alzheimer’s prevention. He shares fascinating insights into the importance of a nutrient-rich diet for supporting cognitive function and preventing neurodegeneration. Dr. Steve Blake also highlights the role of nutrition in optimizing brain structure and function, particularly as we age. We discuss practical ways to incorporate brain-boosting nutrients into your daily routine, how to identify deficiencies, and the key dietary changes that can significantly improve your cognitive health. If you’re looking to improve your brain health and reduce Alzheimer’s risk through nutrition, this episode is a must-listen. Dr. Steve Blake’s advice will empower you to take control of your cognitive health and make smarter, more informed food choices. “It's not just what we don't have in our diet but what we already are eating too much of in our diet that could impact the brain as well .” ~ Dr. Steve Blake, ScD In this Episode 00:00 - Introduction to Dr. Steve Blake 03:16 - Results from the Hawaii Dementia Prevention Trial 06:35 - The importance of a balanced diet for brain health 14:18 - The effect of reducing saturated fat in your diet 18:42 - Why vitamin B-12 and other nutrients are crucial for brain health 38:50 - More information about advanced glycation end products (AGEs) 40:03 - The role of omega-3s in cognitive function 43:19 - Is the ketogenic diet good for people with Alzheimer's? 54:58 - How lipopolysaccharides (LPS) affect our body 1:03:08 - Grains and how they contribute to our health 1:05:37 - Where to source organic food 1:07:03 - Other tips for boosting your brain health 1:12:14 - The future of nutrition studies in relation to brain health Resources: - Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide Connect with Dr. Steve Blake: - Website - https://drsteveblake.com/ - YouTube - https://www.youtube.com/@DrSteveBlakeScD - Email - Steve@drsteveblake.com Connect with Dr. Josh Helman, MD: - Instagram - https://www.instagram.com/greenbrainsMD - Facebook - https://www.facebook.com/greenbrainsmd/ - a href="https://www.linkedin.com/in/doctorjosh"...

    1h 18m
  4. 12/25/2025

    Mold & Mycotoxins Linked to Dementia and Alzheimer’s (What You Must Know) with John Bohde

    Could hidden dangers in your home be impacting your brain health? In this eye-opening conversation, discover how mold and mycotoxins might be contributing to cognitive decline and Alzheimer's disease. I interview John Bohde, co-founder and VP of The Mold Pros, to discuss the shocking connection between mold exposure, mycotoxins, and cognitive decline. John explains how mold can contribute to dementia and brain fog, often in ways we don't immediately recognize. As a leader in the mold inspection and remediation industry, John highlights environmental triggers that can be overlooked, even in homes that appear clean and well-maintained. We talk about how mold can release mycotoxins into the air and what that means for your health. John shares recommendations for identifying hidden mold and mycotoxins in your environment, emphasizing the importance of a proper moisture assessment and advanced testing for those dealing with chronic illness or dementia. Plus, we discuss how the remediation process has evolved and how you can protect yourself from environmental illness. “Everybody thinks, oh, my house is fine. I'm a great housekeeper, and therefore I don't have a problem. One, it oftentimes has nothing to do with how well you keep your home. It's really around how much moisture is in that environment. Second, mold spores are microscopic–you just can't see them.” ~ John Bohde In this Episode 00:00 - Introduction to John Bohde 02:20 - Understanding type 3 Alzheimer’s (toxicity-related) 12:37- The Mold Pros process for mold remediation 17:58 - Why some traditional mold remediation methods do not work 22:23 - The challenges of treating mold toxicity in patients and structures 30:09 - How to find a reliable mold inspector 44:08 - The importance of proper protective gear for mold remediators 50:15 - What to do when you're worried about mold 🎧 Podcast Listener Bonus: The Mold Pros are offering a FREE 30-minute consultation exclusively for podcast listeners. To receive your free consult and an additional discount, be sure to mention “DrJosh” when you book. Resources: - Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide - EPA Tips for Mold Cleanup in Your Home - https://www.epa.gov/mold/mold-cleanup-your-home Connect with John Bohde: - Website - https://www.themoldpros.com/ - LinkedIn - https://www.linkedin.com/in/john-bohde-95bb39b/ Connect with Dr. Josh Helman, MD: - Instagram - https://www.instagram.com/greenbrainsMD - a...

    53 min
  5. 12/18/2025

    Can These Brain Regeneration Tools Help Reverse Alzheimer’s? With Dr. Nick Delgado

    What if the fastest way to improve your brain isn’t just one treatment but three powerful levers working together to reverse cognitive decline? In this episode, I interview Dr. Nick Delgado, a pioneer in hormone optimization, inflammation control, peptide therapy, and lifestyle medicine, to explore what he calls the fastest levers for transforming brain health. We break down how nutrition, hormone balance, and targeted peptides can rapidly shift cognition, reduce inflammation, and support the aging brain.  Dr. Delgado shares stories from over 45 years of clinical experience, including remarkable cases of patients with advanced Alzheimer’s who showed unexpected improvements after strategic interventions. We discuss the roles of triglycerides, dietary fat, cholesterol, and plant-based nutrition in maintaining blood flow to the brain.  We also dive into hormone restoration–testosterone, DHEA, pregnenolone, estriol, progesterone–and how these influence cognition, mood, and neuroprotection. Dr. Delgado explains how each tool can support brain regeneration when used thoughtfully and synergistically.  “Alzheimer's and cognition and so forth, is not only a hormonal decline. It's an arterial problem, it's a lack of circulation, so you want to figure out every way to bring massive amounts of blood flow to that brain.”  ~ Dr. Nick Delgado In this Episode 00:00 - Introduction to Dr. Nick Delgado and his work 04:40 - Early work with nutritionist and longevity researcher Nathan Pritikin 09:15 - Dr. Kempner's high-carb, low-fat diet for cognitive protection 13:07 - Insights from a lifestyle medicine pioneer 27:21 - Why the brain does not need high dietary fat 31:05 - The diet that best prevents brain degeneration 38:57 - Case study: reversing Stage 4 Alzheimer’s with multimodal care 51:37 - Synergy vs. single interventions in neurodegeneration 1:07:50 - The impact of stem cells in neuroregeneration 1:14:46 - New technologies Dr. Delgado is excited about 1:18:51 - Key takeaways from today's conversation Resources: - Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide - Stop Aging Now: Seven Secrets to Look & Feel Great by Dr. Nick Delgado - https://stopagingnowbook.com/ - Brain Fitness by Dr. Robert Goldman - https://www.amazon.com/dp/0385488645 - The Pritikin Diet & Eating Plan - https://www.pritikin.com/pritikin-program#eating-plan Connect with Dr. Nick Delgado:  - Website - https://foreveryoungevent.com/ and https://delgadolabs.com/ - The Delgado Protocol for Health - https://delgadoprotocol.com/ Connect with Dr. Josh Helman, MD: - Instagram - https://www.instagram.com/greenbrainsMD - a href="https://web.facebook.com/people/Dr-Josh-Helman/61558380891088" rel="noopener...

    1h 27m
  6. 12/11/2025

    Why Post-Surgery Delirium Predicts Dementia—and How to Prevent It With Dr. Leah Acker

    Why do some people stay mentally sharp after surgery while others decline even when their brains look identical on scans? In this episode, I explore one of the biggest mysteries in brain health: why two people with the same MRI, the same amyloid burden, and the same risk factors can age so differently. My guest, Dr. Leah Acker, a Harvard-MIT–trained physician-scientist and Duke anesthesiologist, studies the hidden rules of brain resilience and what stress reveals about cognitive decline.  As we talk, Dr. Acker explains how surgery acts as a “stress test for the brain,” exposing vulnerabilities years before symptoms show up. We break down the links between anesthesia, delirium, sleep, heart rate variability, inflammation, and early neurodegeneration, and why postoperative delirium can increase dementia risk up to 12-fold. She also explains why simple EEG changes can predict who is most vulnerable during stress.  We also dive into the future of brain science—from personalized anesthesia to breakthroughs in functional MRI and new Alzheimer’s biomarkers.  If you or a loved one is facing surgery, or if you want to understand how the aging brain really works, this episode is essential. Tune in to learn how to prepare, protect your brain, and build long-term cognitive resilience. “ I tend to think of surgery and anesthesia as a stress test for the brain. It's an emotionally stressful event in general…On top of that, there's a lot of physiological stress that comes with surgery.”  ~ Dr. Leah Acker In this Episode 00:00 - Introduction to Dr. Leah Acker 07:58 - Post-operative delirium and dementia connection 11:08 - Heart health and its impact on inflammation and healing 14:51 - How long does anesthesia stay in the body? 19:36 - Pre-operative preparation to minimize the stress of surgery 23:19 - EEG, alpha waves, and what they reveal about brain health 27:31 - Surgery as a stress test for the brain 33:27 - Tips for patients who have just had a major surgery 44:06 - Biomarkers to determine brain function and Alzheimer's risk 47:23 - What makes the brain respond well to stress? 53:03 - The future of brain research and personalized patient care Resources: - Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide Connect with Dr. Leah Acker:  - Website - ackerlab.com - Email - ackerlabinfo@duke.edu Connect with Dr. Josh Helman, MD: - Instagram - https://www.instagram.com/greenbrainsMD - Facebook - https://www.facebook.com/greenbrainsmd/ - LinkedIn - a...

    1h 1m
  7. 12/04/2025

    The New Science of Reversing Memory Loss: What Actually Works Today With Dr. Robert Love

    What if everything you’ve been told about Alzheimer’s is incomplete and the real solutions are the ones your doctor never mentioned?  In this episode, I sit down with my friend and colleague, neuroscientist Dr. Robert Love, to break down the most important and most overlooked steps you can take to prevent, slow, and even reverse cognitive decline. Together, we share real stories from our clinic, where we help patients improve memory and quality of life using strategies far beyond the standard “there’s nothing you can do” message most families hear. You’ll hear Robert explain the science behind stem cells, cerebrolysin, hydrogen gas therapy, sauna, exercise, and key supplements like NMN, including where they truly fit into an Alzheimer’s prevention plan. We also unpack the political and pharmaceutical roadblocks that keep many of these tools out of mainstream healthcare, and why staying informed is your most powerful form of prevention. By the end of this conversation, you’ll walk away with actionable steps you can start today, like lowering inflammation, improving mitochondrial function, and creating a brain-healthy environment that supports long-term resilience. If you or someone you love is experiencing cognitive issues, this episode offers both clarity and hope. To learn more about our work, visit the Brain Power Clinics:  https://brainpowerclinics.com/ “Wherever you are now, whether you're 40 or 50 or 90, start where you are right now and invest in your health to help reduce the risk of chronic disease later.”  ~ Dr. Robert Love In this Episode 00:00 - Introduction to Dr. Robert Love and his work 02:06 - Our approach to preventing and reversing Alzheimer’s 03:47 - How stem cells can help improve your health 07:56 - Cerebrolysin explained: Powerful brain growth booster 16:11 - How pharma–FDA ties shape medical decisions 23:04 - NMN: Industry pressure and quality issues 36:57 - Hydrogen gas for mitochondria and cognitive support 46:04 - Sauna’s role in lowering Alzheimer’s risk 47:52 - Toxins, plastics, and rising environmental risks 53:48 - How to work with our Alzheimer’s clinic Resources: - Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide - Learn More About Reversing Alzheimer's at Brain Power Clinics - https://brainpowerclinics.com/ - 100 Simple Things You Can Do to Prevent Alzheimer's and Age-Related Memory Loss by Jean Carper - https://www.amazon.com/dp/0316086851 - The Body: A Guide for Occupants by Bill Bryson - https://www.amazon.com/dp/0385539304 Connect with Dr. Robert Love:  - Website - https://roarlionsmane.net/ - Instagram -...

    56 min
  8. 11/27/2025

    Can Intermittent Fasting Prevent Alzheimer’s? Dr. Doug Graham Reveals the Science

    Could intermittent fasting be the missing link in preventing Alzheimer’s and improving brain health? In this episode, we dive into the facts and myths surrounding fasting, specifically intermittent fasting, and its role in promoting autophagy for brain health. If you've ever wondered whether fasting can help with insulin resistance, one of the main culprits behind cognitive decline, then you're in the right place. Dr. Doug Graham, a renowned fasting coach and author of the 80/10/10 Diet, returns to discuss fasting facts from fiction. We’ll discuss the fine line between therapeutic benefits and muscle wasting in older adults, as well as how fasting influences everything from brain function to metabolism. This episode is packed with valuable insights, so grab your notebook as we discuss the science behind the power of fasting. Whether you’re a fasting newbie or an experienced practitioner, Dr. Graham’s decades of knowledge on fasting, nutrition, and lifestyle design will provide you with practical advice to safely incorporate fasting into your life. “Fasting, from a health perspective, is getting into a state of deep, profound rest–deeper than any other rest, deeper than sleep. It's a deep state of rest where the body does its work.”  ~ Dr. Doug Graham In this Episode 00:00 - Introduction to Dr. Doug Graham & fasting for health 13:14 - The science behind fasting 20:04 - Types of fasting and their benefits 32:21 - Success stories & recommendations 49:07 - Fasting for someone who's taking medications 56:26 - Breaking the fast safely 59:16 - Dr. Graham's unique fasting protocol 1:03:44 - The role of the mind in achieving your goal 1:15:20 - Dr. Graham's insight into fasting and stress 1:26:23 - The reason people would want to fast Resources: - Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide Connect with Dr. Doug Graham:  - Website - https://foodnsport.com/index.php - Instagram - https://www.instagram.com/drdouglasgraham/ - YouTube - https://www.youtube.com/@FoodnSport/featured Connect with Dr. Josh Helman, MD: - Instagram - https://www.instagram.com/greenbrainsMD - Facebook - https://www.facebook.com/greenbrainsmd/ - LinkedIn - https://www.linkedin.com/in/doctorjosh - a href="https://www.tiktok.com/@greenbrainsmd" rel="noopener...

    1h 32m
4.7
out of 5
12 Ratings

About

Welcome to Alzheimer’s Breakthrough with Dr. Josh Helman, MD, the transformative podcast that delves into the root causes of cognitive decline and provides real solutions for preventing—and even reversing—Alzheimer’s. Hosted by Dr. Josh Helman, MD, a Harvard-trained physician with advanced degrees in biochemistry, this show is designed for individuals living with Alzheimer’s, their loved ones, and anyone determined to preserve and improve brain health. Each week, Dr. Josh demystifies the complexities of dementia, unpacks the latest breakthroughs in neurodegenerative research, and shares actionable lifestyle strategies drawn from his six years of clinical experience reversing Alzheimer’s. From tackling nutritional deficiencies and toxin exposure to exploring cutting-edge diagnostics and mind-body interventions, Alzheimer’s Breakthrough with Dr. Josh Helman, MD, turns every challenge into an opportunity to reclaim cognitive vitality and hope. If you’re ready to discover evidence-based approaches that can restore mental clarity and empower you or your loved ones, tune in to Alzheimer’s Breakthrough with Dr. Josh Helman, MD, on Spotify, Apple Podcasts, or YouTube. Get ready to embrace a brighter future—one breakthrough at a time.

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