225 episodes

Professor Jim Al-Khalili talks to leading scientists about their life and work, finding out what inspires them and asking what their discoveries might do for us in the future.

The Life Scientific BBC

    • Science
    • 4.6 • 131 Ratings

Professor Jim Al-Khalili talks to leading scientists about their life and work, finding out what inspires them and asking what their discoveries might do for us in the future.

    Neil Ferguson on modelling Covid-19

    Neil Ferguson on modelling Covid-19

    Neil Ferguson is known to many as Professor Lockdown. The mathematical models he created to predict the spread of Covid-19 were influential but, he says, it took him quite a long time to be persuaded that full lockdown was a good idea. A physicist by training, Neil switched from studying string theory to the spread of disease and presented scientific advice to government during the BSE crisis, an outbreak of foot and mouth disease in livestock in 2001 and the swine flu pandemic of 2009. In January 2020, he issued his first report on Covid-19 estimating the extent of the outbreak in Wuhan City in China. In March, he predicted that 510,000 people in the UK could die if nothing was done to mitigate the spread of this pandemic. Does he stand by that prediction? And how worried is he now? Jim Al-Khalili talks to Neil Ferguson about his life and work, the tricky relationship between politics and science and asks if he has any regrets about lockdown.
    Producer: Anna Buckley for BBC Radio Science

    • 37 min
    Sarah Gilbert on developing a vaccine for Covid-19

    Sarah Gilbert on developing a vaccine for Covid-19

    Sarah Gilbert started working on a vaccine for Covid-19 just as soon as the virus genome was sequenced. Within weeks, she had a proof of principle. By early April, her team at the Jenner Institute in Oxford had manufactured hundreds of doses ready for use in clinical trials. In phase one of these trials, completed in July, this vaccine was shown to be safe for use in a thousand healthy volunteers, aged between 18 and 55. It also provoked exactly the kind of immune response to Covid-19 that Sarah was hoping to achieve. Larger scale clinical trials are currently underway in the UK, South Africa and Brazil. If everything goes according to plan and the vaccine meets all the necessary regulatory standards, it will be manufactured in multiple locations including the Serum Institute in India and made available for use in low to middle income countries. AstraZeneca has already committed to making two billion doses, each costing about $4. The UK has an order in for 100 million. Sarah talks to Jim Al-Khalili about her life and work. As a young woman, she nearly gave up on a career in science. Now she’s in charge of one the most successful vaccine projects in the world. How did Sarah and her Oxford team get so far, so fast in developing a vaccine against Covid-19?
    Producer: Anna Buckley

    • 29 min
    Steve Haake on technology, sport and health

    Steve Haake on technology, sport and health

    Steve Haake,has spent much of his career using technology to help elite sports people get better, faster and break records. He has turned his hand to the engineering behind most sports, from studying how golf balls land, to designing new tennis racquets and changing the materials in ice skates. He’s now Professor of Sports Engineering at Sheffield Hallam University and was the Founding Director of the Advanced Wellbeing Research Centre there.

    Since the 2012 London Olympics, Steve has also been working to improve the health and wellbeing of all of us. As Chair of the Parkrun Research Board he’s heavily involved in this international phenomenon in which thousands of people have sprinted, jogged and stumbled around a 5-kilometre course on Saturday mornings, which he’s shown really does encourage people to be generally more active.

    Jim al-Khalili talks to Steve Haake about how he got from a physics degree to being one of the leading sports engineers in the world, and how we can all improve our health by moving more.

    • 28 min
    Francesca Happé on autism

    Francesca Happé on autism

    When Francesca Happé started out as a research psychologist thirty years ago, she thought she could easily find out all there was to know about autism – and perhaps that wouldn’t have been impossible as there were so few papers published on it. Francesca’s studies have increased our knowledge of how people with autism experience the world around them, and their social interactions. She’s looked at their brains using various imaging techniques, studied the families of people with autism to explore their genetics, and raised awareness of how the condition can appear differently in women than in men. Jim al-Khalili talks to Francesca, now Professor of Cognitive Neuroscience at the Institute of Psychiatry, Psychology and Neuroscience in London, about her research career and her current projects, including how people with autism experience mental health issues, such as PTSD.

    • 28 min
    Heather Koldewey on marine conservation

    Heather Koldewey on marine conservation

    Professor Heather Koldewey wants to protect our oceans from over-fishing and plastic pollution. An academic who is not content to sit back and let the science speak for itself, she wants to turn science into action and has found conservation allies in some unexpected places. Working with a carpet manufacturer, she created Net-Works, a business that turns old fishing nets into high-end carpet tiles and she has collaborated with Selfridges department store to give marine conservation a make-over. A research career that began studying the genetics of brown trout in Welsh rivers took her to the Philippines to save seahorses and a job running the aquarium at London Zoo. In 2018, she was made a National Geographic Fellow. Heather tells Jim Al-Khalili why, despite all the challenges to marine life, she remains an ‘ocean optimist’ and how she learned to drop her ‘scientific seriousness’.
    Producer: Anna Buckley

    • 28 min
    Dale Sanders on feeding the world

    Dale Sanders on feeding the world

    Professor Dale Sanders has spent much of his life studying plants, seeking to understand why some thrive in a particular environment while others struggle. His ground breaking research on their molecular machinery showed how plants extract nutrients from the soil and store essential elements. Since plants can’t move, their survival depends on these responses. In 2020, after 27 years at the University of York, he became the Director of the John Innes Centre in Norwich, one of the premier plant research institutions in the world. Meeting the food needs of a growing global population as the climate changes is a major challenge. And, Dale says, it’s not only about maximising yields. We need crops that are more resilient and more nutritious. Drought resistant crop varieties, for example. And zinc-rich white rice. Dale talks to Jim about how plant science is helping to feed the world in a sustainable way and why plant scientists don’t always get the recognition they deserve.
    Producer: Anna Buckley

    • 32 min

Customer Reviews

4.6 out of 5
131 Ratings

131 Ratings

llamaneck ,

Keeps Interest if you love learning WHY...

Gonna keep Listening!

Brit by the Bay ,

Insights and ideas

Beautifully done. Jim the physicist does an amazing job of making a wide range of science areas seem totally accessible, understandable and within reach of ordinary mortals! Love the mix of men, women and topics. Thanks BBC!

Lundgrenn ,

Helped me carry on

This podcast, specifically the interview with Dr. Andrea Sella, helped keep me motivated to finish graduate school. Thank you.

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