Weight Loss And ...

Holly Wyatt & James Hill
  • 5.0 (22)
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Your go-to hangout for everything weight loss… and beyond! “Weight Loss and…” is brought to you by the University of Alabama at Birmingham (UAB) and hosted by seasoned experts in weight management, Dr. James Hill and Dr. Holly Wyatt. We’re your friendly guides through the maze of weight loss, but with a fun twist. We’re not here to preach the latest fad diet or promise a miracle workout. Instead, we’re all about embracing the journey, acknowledging there’s more than one way to hit your health goals, and having a good laugh while we’re at it. We get it: weight loss can be tough, and sometimes pretty serious business. But why can’t it also be enjoyable? With a side of humor, we’ll bring you science-backed insights, real-life stories, and some hard truths. (Spoiler alert: there’s no magic answer - but that doesn’t mean we can’t find what works best for you.) “Weight Loss and…” is your inclusive space to explore, question, and learn — and to feel part of a community along the way. This isn’t just about shedding pounds. It’s about gaining perspective, building better habits, and enjoying the ride. So if you’re up for honest conversations about weight loss - spiced with a little science and a whole lot of fun - pull up a chair, plug in those earbuds, and let’s see where this journey takes us.

  1. From Food Noise to Clarity: Bill's GLP-1 Journey

    13H AGO

    From Food Noise to Clarity: Bill's GLP-1 Journey

    Weight loss isn’t just about the number on the scale. It’s about reclaiming your life. When you’ve been carrying excess weight for years, it’s easy to start accepting limitations as your new normal. Skipping events because of walking. Staying in the car while others explore. Wondering if you’ll see your future grandchildren grow up. But what if the right support could help your body work with you instead of against you? What if losing weight didn’t have to mean constant hunger and willpower battles? Join Holly and Jim as they sit down with Bill Tollett, a former school principal and coach who lost over 120 pounds and rediscovered what living fully actually means. This conversation goes beyond the mechanics of weight loss. Bill shares the mental shifts that surprised him most, the challenges of navigating insurance hurdles, and why he now describes himself as feeling “capable” for the first time in decades. Whether you’re considering medication, struggling with where to start, or simply curious about what sustainable change actually looks like, Bill’s story offers honest insights into a journey that’s transformed not just his body, but his entire approach to life. Discussed on the episode: Why one doctor’s blunt comment became the catalyst for changeThe unexpected mental clarity that came with medication (and why it felt like being a superhero)How Bill built exercise into his day without joining a gym or running marathonsThe three different reactions people have when they see his transformationWhat “food noise” really feels like and what life is like when it quiets downWhy Bill says this isn’t cheating, it’s “leveling the playing field.”

    43 min
  2. Why Obesity Care Still Fails People with Fatima Cody Stanford

    FEB 11

    Why Obesity Care Still Fails People with Fatima Cody Stanford

    Have you ever done everything right, eaten well, moved your body, maybe even started a new medication, and still felt like the system wasn’t working for you? You’re not alone. And the reason might not be what you think. Join Holly and Jim as they sit down with Dr. Fatima Cody Stanford, an obesity medicine physician and associate professor at Harvard Medical School, and one of the boldest voices shaping how we think about obesity care today. Dr. Stanford treats obesity as the complex, chronic disease it truly is, and she’s not afraid to call out the bias, broken systems, and outdated myths that get in the way. This is a conversation that will change the way you see weight loss, not just as something you do, but as something you deserve support with. Discussed on the episode: The shocking age at which weight bias begins and why it’s not where you’d expectWhy over 80% of physicians carry bias toward patients with excess body weight, and what one doctor is doing to flip the scriptThe real reason GLP-1 medications aren’t the magic bullet and why that’s actually okayWhy some patients respond brilliantly to these drugs and others don’t, and what you absolutely cannot do to change thatThe one nutrient and one type of exercise that matter most when you’re losing weight on medicationWhat happens when insurance pulls the rug out, and the creative strategies doctors use to keep patients on trackThe “Ozempic baby” phenomenon: what the early science is actually showingWhy the new oral Wegovy pill might not be the game-changer everyone is hoping forThe grocery store moment that completely changed one doctor’s understanding of obesity

    49 min

  3. FEB 4

    The Detox No One Talks About (But Everyone Needs)

    New Year’s resolutions often start with motivation and willpower, but how long does that really last? What if the problem isn’t your discipline, but the world you’ve built around yourself? Your refrigerator, your bedroom setup, even the people you spend time with, are quietly shaping every choice you make. Join Holly and Jim as they reveal why an environmental detox might be the smartest move you can make this year. Forget juice cleanses and deprivation, this is about redesigning your space and social circle to make healthy choices the easy ones. You’ll learn how your physical surroundings impact everything from late-night snacking to your morning mindset, and why even GLP-1 users shouldn’t skip this critical step. Whether you live in a “food desert” or work in a toxic office environment, you’ll walk away with practical strategies to take control of what you can and create a micro-environment that actually supports your goals. Discussed on the episode: Why willpower works great for 4-6 weeks, then crashes spectacularly.The sneaky reason people on GLP-1s should detox their environment now (before it’s too late)The three-step detective process for identifying what’s quietly sabotaging youHow removing your phone charger from the bedroom could transform your sleepThe two-column social mapping exercise that reveals who’s really supporting your goalsWhy telling your spouse to “eat healthier” never works, and what doesThe clever strategy for influencing the people you can’t (or won’t) remove from your lifeWhat Holly’s new Peloton treadmill and hydroponic herb garden reveal about smart environmental designHow to create a supportive micro-environment even in Alabama’s summer heat or without neighborhood sidewalksResources and links mentioned: Book: Losing the Weight Loss Meds by Holly Wyatt and James Hill (weightwisdom.com)

    40 min
  4. How to Thrive on a Vegan Diet Without Gaining Weight with Daphne Bascom

    JAN 28

    How to Thrive on a Vegan Diet Without Gaining Weight with Daphne Bascom

    Going vegan for weight loss? You might be in for a surprise. Despite what social media influencers claim, switching to a plant-based diet doesn’t guarantee the pounds will melt away. In fact, many vegans struggle with weight gain even when they think they’re eating healthy. The truth is, whether you’re eating steak or tofu, the same principles of weight management still apply. You can absolutely lose weight and thrive on a vegan diet, but it requires the same intentionality, planning, and understanding of nutrition fundamentals as any other approach. The good news? It’s never been easier to succeed as a plant-based eater when you know what to focus on. Join Holly and Jim as they sit down with Dr. Daphne Bascom, Chief Operating Officer of The Vegan Gym and an MD/PhD who brings a refreshingly balanced perspective to plant-based nutrition. Daphne shares why she became vegan later in life, busts common myths about vegan diets and weight loss, and reveals the surprising similarities between coaching vegans and omnivores. You’ll discover practical strategies for managing weight on a plant-based diet, learn which “healthy” vegan foods might be sabotaging your goals, and find out why mindset matters just as much as what’s on your plate. Discussed on the episode: The biggest myth about vegan diets that keeps people stuck and gaining weightWhy being vegan doesn’t make you “impervious to chronic disease.”The surprising food Daphne keeps in her purse when traveling (and why you might want to try it)How to navigate restaurants, airports, and social situations without derailing your goalsThe one non-negotiable supplement every vegan needs to takeWhether plant-based proteins are really inferior for building muscle and recoveryThe “Oreo vegan” trap and how to avoid ultra-processed plant-based foodsWhy nuts might be sabotaging your weight loss (even though they’re healthy)The energy density principle that works whether you’re vegan or notHow the anabolic window for protein has evolved (it’s longer than you think)Resources and Links: The Vegan Gym: https://www.thevegangym.com/Thrive on Plants Podcast: https://podcasts.apple.com/us/podcast/thrive-on-plants/id1793550910Thrive on Plants Community: https://www.skool.com/thrive-on-plants/aboutThe Vegan Gym Podcast: https://podcasts.apple.com/us/podcast/the-vegan-gym-podcast/id1358557895Cronometer App: https://cronometer.com/Game Changers Documentary: https://gamechangersmovie.com/Books mentioned: How Not to Die and How Not to Age by Dr. Michael Greger: https://www.amazon.com/Hardcover-Cookbook-Michael-Greger-Collection/dp/9124302686Losing the Weight Loss Meds by Holly Wyatt and James Hill: https://www.weightwisdom.com/

    49 min
  5. How GLP-1 Medications Changed the Science and Art of Sustainable Weight Loss with Arne Astrup

    JAN 21

    How GLP-1 Medications Changed the Science and Art of Sustainable Weight Loss with Arne Astrup

    The GLP-1 medications transforming weight loss didn’t appear overnight. They’re the result of decades of groundbreaking research that fundamentally changed how we understand appetite and obesity. But how did scientists first discover that this hormone could help people lose weight? And what does this history mean for anyone using these medications today? Join Holly and Jim as they sit down with Dr. Arne Astrup, one of the pioneering researchers who helped uncover GLP-1’s role in appetite regulation back in the 1990s. Dr. Astrup has spent over three decades at the forefront of obesity research at the University of Copenhagen and the Novo Nordisk Foundation. In this fascinating conversation, he takes us back to when obesity was still seen as a willpower problem, reveals the serendipitous collaboration that led to discovering GLP-1’s satiety effects, and shares critical insights about using these medications safely and effectively. Whether you’re currently using GLP-1 medications, considering them, or simply curious about the science, this episode offers essential perspective from someone who’s witnessed the entire journey from early physiology experiments to today’s real-world treatments. You’ll discover why lifestyle still matters in the era of highly effective medications, and walk away with a deeper understanding of both the promise and the limitations of these groundbreaking drugs. Discussed on the episode: The surprising mindset shift in the 1990s that changed how medicine views obesityWhy a diabetes researcher and an appetite scientist became unlikely collaboratorsThe first human experiment that proved GLP-1 reduces hunger (and the lunch buffet that made it possible)Why GLP-1 medications are so much “cleaner” than previous weight loss drugsThe protein malnutrition risk that doctors aren’t talking about enough.Why half of patients stop taking these medications within months, and what that meansThe one combination that could let you reduce or stop GLP-1s without regaining weightWhy calling these medications “the easy way out” completely misses the pointWhat a leading researcher wants to accomplish after decades of groundbreaking work

    45 min
  6. Why Your Brain Won't Stop Thinking About Food with Emily Dhurandhar

    JAN 14

    Why Your Brain Won't Stop Thinking About Food with Emily Dhurandhar

    Food noise. If you’ve heard the term, you probably know exactly what it means. If you haven’t, you might be about to have a lightbulb moment. It’s that relentless mental chatter about food, not hunger, not cravings, but constant, unwanted thoughts that just won’t quit. For years, people struggling with this phenomenon didn’t even have words for it. They thought it was a willpower problem. It wasn’t. And now, thanks to groundbreaking research, we finally have a way to understand, measure, and potentially treat this invisible burden that affects people across the weight spectrum. Join Holly and Jim as they sit down with Dr. Emily Dhurandhar, Director of Research Special Projects at Texas Tech University Health Sciences Center, and lead author of the RAID-FN Inventory, the first validated tool to measure food noise. Discover why patients, not clinicians, coined this term, how GLP-1 medications are revealing what many have silently endured, and what the future holds for treating this pervasive issue. Discussed on the episode: Why food noise is completely different from normal thoughts about foodThe surprising discovery about who experiences food noise (hint: it’s not just people with obesity)What turning off a kitchen fan has to do with understanding these medicationsHow bodybuilders and endurance athletes might experience food noise differentlyWhy your environment in the 1940s versus today changes everythingThe one word clinicians need to stop assuming about food noiseWhat to do if you think you’re experiencing this, but your doctor has never heard of it

    44 min
  7. Obesity Medications and the Coming Revolution in Care with Louis Aronne

    JAN 7

    Obesity Medications and the Coming Revolution in Care with Louis Aronne

    For decades, people with obesity were told the solution was simple: eat less, move more, try harder. When that didn’t work, they were blamed. But science has always told a different story: obesity is a chronic, biologically driven disease, just like diabetes or hypertension. And right now, we’re witnessing the most significant transformation in obesity medicine that has ever happened. The new GLP-1 medications like Wegovy and Zepbound are making headlines everywhere, but with breakthrough treatments come big questions. Who should take them? How do you know which one is right for you? What happens when you stop? And with millions of people getting these medications online or from providers with little expertise, how do you ensure you’re getting safe, effective care? Join Holly and Jim as they sit down with Dr. Louis Aronne, one of the true pioneers who shaped this revolution from the very beginning. For over 30 years, Dr. Aronne has been on the front lines, treating patients and conducting research at one of the premier obesity centers in the country. He’ll share the real story behind these medications, what he’s learned from treating 9,000 patients, and where obesity treatment is heading next. Discussed on the episode: The mouse experiment from the 1980s that changed everything about how we understand weightWhy some people feel amazing on Wegovy while others do better on ZepboundThe creative dosing strategies that help patients who can’t tolerate standard dosesWhat happens to the majority of people who stop taking GLP-1 medicationsThe surprising parallel between treating obesity and treating high blood pressureWhy registered dietitians could be the perfect providers for obesity careThe 15 new medications coming in the next five years that will transform accessHow these medications prevent 94% of diabetes cases in people with prediabetesThe simple eating strategy that works almost like taking medicineWhat it really means when people say taking medication is cheating

    52 min
  8. How Your Biology Fights Weight Loss Maintenance with Paul MacLean

    12/31/2025

    How Your Biology Fights Weight Loss Maintenance with Paul MacLean

    You’ve done it. You’ve lost the weight. But then something shifts. The hunger gets louder. Food becomes more tempting. The scale starts creeping back up. You’re doing everything right, yet your body seems to be fighting you at every turn. If this sounds familiar, you’re not alone, and more importantly, it’s not your fault. The truth is, after weight loss, your body launches a powerful biological response designed to bring that weight back. It’s not about willpower or discipline. It’s about survival mechanisms that were built for a world without grocery stores on every corner. Understanding what’s actually happening inside your body after weight loss changes everything from how you approach maintenance to how you talk to yourself when things get hard. Join Holly and Jim as they sit down with Dr. Paul MacLean, one of the world’s leading experts on the biology of weight regain. You’ll discover why keeping weight off requires completely different strategies than losing it, what your metabolism is really doing after weight loss, and the science-backed tools that can help you succeed long-term despite your biology working against you. Discussed on the episode: The powerful rubber band analogy that explains why your body fights to regain weightWhat’s really happening at the cellular level when you lose weight (and why it persists)Why the speed of weight loss may matter less than you thinkThe controversial truth about whether metabolic adaptation ever goes awayOne scientist’s personal journey with weight struggle and GLP-1 medicationsThe myth about starting with a “clean slate” after weight loss

    45 min
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About

Your go-to hangout for everything weight loss… and beyond! “Weight Loss and…” is brought to you by the University of Alabama at Birmingham (UAB) and hosted by seasoned experts in weight management, Dr. James Hill and Dr. Holly Wyatt. We’re your friendly guides through the maze of weight loss, but with a fun twist. We’re not here to preach the latest fad diet or promise a miracle workout. Instead, we’re all about embracing the journey, acknowledging there’s more than one way to hit your health goals, and having a good laugh while we’re at it. We get it: weight loss can be tough, and sometimes pretty serious business. But why can’t it also be enjoyable? With a side of humor, we’ll bring you science-backed insights, real-life stories, and some hard truths. (Spoiler alert: there’s no magic answer - but that doesn’t mean we can’t find what works best for you.) “Weight Loss and…” is your inclusive space to explore, question, and learn — and to feel part of a community along the way. This isn’t just about shedding pounds. It’s about gaining perspective, building better habits, and enjoying the ride. So if you’re up for honest conversations about weight loss - spiced with a little science and a whole lot of fun - pull up a chair, plug in those earbuds, and let’s see where this journey takes us.

Information

  • Creator
    Holly Wyatt & James Hill
  • Years Active
    2024 - 2026
  • Episodes
    115
  • Rating
    Clean
  • Copyright
    © Copyright 2025 Holly Wyatt & James Hill
  • Show Website
    Weight Loss And ...

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