We're not getting any younger... yet.

The Buck Institute
  • 5.0 (49)
  • LIFE SCIENCES
  • UPDATED WEEKLY
We're not getting any younger... yet.

Why do some of us age gracefully and others don’t? How do our bodies and minds experience aging at the cellular and molecular level? Why do we even age to begin with? And maybe most importantly, can we do anything about it? Join host Gordon Lithgow at the Buck Institute in California as he speaks with some of the brightest scientific stars on the planet to search for – and actually find answers to – these questions and many more.

  1. 07/24/2024

    Nathan Price: Scientific Wellness and AI at the Forefront

    What do we really want from our healthcare system, and how can AI help us get it sooner? In our final episode of season two, Gordon talks with visionary systems biology expert Nathan Price about the emergence of scientific wellness, what we can learn from our digital twins, and how using AI to predict health outcomes can help us transform our understanding of aging and disease—potentially adding years of healthy life.Dr. Nathan Price is a distinguished scientist and leader in the field of hea...

    33 min

  2. 07/10/2024

    Luigi Ferrucci: Resilience as Medicine

    Few people have as much experience with patient care and long-term research as the celebrated geriatrician and epidemiologist Luigi Ferrucci. Listen in as he speaks with Gordon about his journey from acute care to population studies, the effective design of clinical trials, and moving towards predictive medicine so we can use our natural resilience to maintain health as we age.Dr. Luigi Ferrucci is a geriatrician and an epidemiologist who conducts research on the causal pathways leading to pr...

    46 min

  3. 06/12/2024

    Andrea Maier: From Potential to Practice

    The movement to integrate longevity treatments into clinical care is making strides. How can we ensure they are evidence-based, accessible, and personalized? World-renowned geroscientist Andrea Maier has been leading the way with innovative clinical trials and cutting edge research. In this episode, she talks with Gordon about the current state of the field, why we need a variety of clocks and interventions, what we can all do now to age better, and what the future of clinical practice looks ...

    36 min

  4. 05/29/2024

    Daniel Belsky: Measuring the Pace of Aging

    Our chronological age doesn’t tell us much about how well our bodies are aging, but scientists have developed many ways to measure changes at the cellular and molecular levels, including the rate of change, that can suggest ways to improve health at every stage of life. Follow along as Gordon speaks with Daniel Belsky of Columbia University about DNA methylation, the effects of famine and poverty on aging biology, studying the exposome, and how to create equitable access to potential aging in...

    39 min

  5. 05/15/2024

    Kristen Fortney: Finding Targets for Aging Interventions

    Of all the biochemical changes that occur with aging, what really matters? How can we use the incredible amount of health data available today to discover the best targets for interventions? In this episode, Kristen Fortney of BioAge talks with Gordon about the latest research in proteomics and metabolomics, the importance of muscle loss, and the challenge of measuring the right endpoints for effective treatment and regulatory approval.Kristen Fortney is the co-founder and CEO of BioAge, a cl...

    27 min

  6. 05/01/2024

    Valter Longo: Fasting for Health and Longevity

    What is the relationship between diet, chronic disease, and aging? Can we delay or reverse the effects of aging at the cellular level by following a fasting-mimicking diet? Listen in as Gordon speaks with Valter Longo of the Longevity Institute at USC about epigenetic reprogramming, turning on Yamanaka factors, and restoring our cells to a youthful state based on over 30 years of research on diet and fasting.Dr. Valter Longo is the Edna M. Jones Professor of Gerontology and Biological Science...

    29 min

  7. 04/17/2024

    Satchin Panda: The Age of Circadian Disruption

    Our modern world is full of potential disruptions to sleep. But as we learn more about circadian rhythm, we find that it influences everything from metabolism to mental health in different ways as we age. In this episode, Satchin Panda of the Salk Institute guides Gordon through the many interactions between sleep behavior and biology. Together they explore how new insights can help us improve our sleep health, and how researchers might target circadian rhythm to modulate the effects of aging...

    31 min

  8. 04/03/2024

    Laura Carstensen: The Purpose and Promise of Longer Lives

    What is the goal of living longer? It’s not simply to celebrate a number, but to do something meaningful with that time. Renowned Stanford psychologist Laura Carstensen speaks with Gordon about the experience of aging, in the past and in the future, and why changes in culture must accompany changes in healthspan so we can flourish as a society.Laura L. Carstensen is Professor of Psychology at Stanford University where she is the Fairleigh S. Dickinson Jr. Professor in Public Policy and foundi...

    38 min
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5
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49 Ratings

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Why do some of us age gracefully and others don’t? How do our bodies and minds experience aging at the cellular and molecular level? Why do we even age to begin with? And maybe most importantly, can we do anything about it? Join host Gordon Lithgow at the Buck Institute in California as he speaks with some of the brightest scientific stars on the planet to search for – and actually find answers to – these questions and many more.

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