8 episodes

Interviews with the leading scientists and innovators, hosted by Global Parents for Eczema Research (GPER), a non-profit led by parents of children with eczema.

Learn more about GPER and subscribe to this podcast at: parentsforeczemaresearch.org

Eczema Breakthroughs Global Parents for Eczema Research (GPER)

    • Medicine
    • 5.0 • 3 Ratings

Interviews with the leading scientists and innovators, hosted by Global Parents for Eczema Research (GPER), a non-profit led by parents of children with eczema.

Learn more about GPER and subscribe to this podcast at: parentsforeczemaresearch.org

    Defining Eczema Types and Preparing for the Precision Medicine Revolution with Dr. Thomas Bieber

    Defining Eczema Types and Preparing for the Precision Medicine Revolution with Dr. Thomas Bieber

    How close are we to targeted treatments designed to each person with eczema? As parents, we often hear from people about a miracle approach that “cured” their or their child’s eczema, only to find that this same approach doesn’t work for us. We are continually reminded of the many different ways that eczema can appear and feel, and how people respond differently to different treatments. Right now, we have a largely “trial and error” approach to treating eczema but what will the future look like as we begin to understand eczema variation, subtypes, and personalized medicine? In this episode of the Eczema Breakthroughs podcast we chat with Professor Thomas Bieber who is chair and director of the department of dermatology and allergy at the University of Bonn in Germany. His cutting edge research focuses on biomarker discovery and precision medicine in allergic skin diseases, and he was a speaker on the topic of risk stratification at the recent Revolutionizing Atopic Dermatitis global conference (http://www.revolutionizingad.com/) in April.  
    Research referenced in this episode:
    Eczema types: Where are we and where should we go? (https://www.jacionline.org/article/S0091-6749(17)30148-3/fulltext)

    • 33 min
    Tales from the Frontlines: Parents Share their Eczema Stories and Insights for World Atopic Eczema Day

    Tales from the Frontlines: Parents Share their Eczema Stories and Insights for World Atopic Eczema Day

    In this episode six parents of children with eczema from around the world share common experiences, challenges and silver linings from their eczema journeys, and dispel myths and misperceptions about the condition. Join us for this special edition of Eczema Breakthroughs recorded for World Atopic Eczema Day (#atopiceczemaday), which takes place annually on September 14th. Episode 7 is co-hosted with Keri Kelley.

    • 30 min
    Natural Killer Cells

    Natural Killer Cells

    What do the Iditarod and the immune system have in common? How can we harness the body’s defenses for fighting off infections and invaders to tackle eczema and its complications, including eczema herpeticum.  Our guest for this episode of Eczema Breakthroughs is Dr. Brian Kim, Assistant Professor of Dermatology, Anesthesiology, Pathology and Immunology, and Co-Director of the Center for the Study of Itch at Washington University School of Medicine in St. Louis. His laboratory focuses on the immune mechanisms that underlie skin inflammation and the sensation of itch, and his groundbreaking translational research is showing new ways for addressing eczema by priming – rather than discouraging – the immune system. 
    Research referenced in this episode: Revving up the immune system may help treat eczema (https://medicine.wustl.edu/news/revving-up-immune-system-may-help-treat-eczema/)

    • 24 min
    Dispatches from the frontlines of the "Battle of the Bacteria" with Dr. Richard Gallo

    Dispatches from the frontlines of the "Battle of the Bacteria" with Dr. Richard Gallo

    There’s a battle underway on the skin between bacteria that make eczema worse and bacteria that can improve eczema symptoms. This fascinating discussion with Dr. Richard Gallo, Chairman of the Department of Dermatology at the University of California-San Diego, explains his ground-breaking research approach which amplifies the presence of “good” bacteria in order to control overgrowth of problematic strains, like Staph aureus, and ultimately help people with eczema.
     
    This podcast was recorded in 2018 as part of GPER’s research meetup series.
     
    Research referenced in this podcast:
    Eczema-associated bacteria may be kept in check by a different microbe (about:blank)
    The microbiome in patients with atopic dermatitis (https://www.jacionline.org/article/S0091-6749(18)31664-6/abstract)
    Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis (https://stm.sciencemag.org/content/9/378/eaah4680)

    • 24 min
    A Roadmap for Navigating the New Eczema Treatment Landscape with Dr. Eric Simpson

    A Roadmap for Navigating the New Eczema Treatment Landscape with Dr. Eric Simpson

    Almost every week we hear about new treatments for eczema, many with names that are hard to pronounce and even harder to remember. After a long drought, we’re suddenly experiencing a downpour in new options, but for parents and patients, it’s hard to navigate this evolving landscape. Dr. Eric Simpson, a dermatologist with OHSU and leading expert on new eczema treatments, walks us through what’s new, what’s coming, and how to make sense of it all. 
    Research referenced in this podcast:
    Systemic Immunomodulatory Treatments for Patients With Atopic Dermatitis (https://jamanetwork.com/journals/jamadermatology/fullarticle/2765026)
    Efficacy and Safety of Dupilumab in Adolescents With Uncontrolled Moderate to Severe Atopic Dermatitis (http://Efficacy%20and%20Safety%20of%20Dupilumab%20in%20Adolescents%20With%20Uncontrolled%20Moderate%20to%20Severe%20Atopic%20Dermatitis)
    Therapeutic Pipeline for Atopic Dermatitis: End of the Drought?
     
    This podcast was co-hosted by the Revolutionizing Atopic Dermatitis Conference (http://revolutionizingad.com/)with support from Sanofi Genzyme and Regeneron.

    • 26 min
    Systemic steroids? Antihistamines? A critical look at common treatment practices with Dr. Jonathan Silverberg

    Systemic steroids? Antihistamines? A critical look at common treatment practices with Dr. Jonathan Silverberg

    Oral and systemic steroids are used to treat eczema all the time, but are they safe and do they make sense for a long-term chronic disease? Antihistamines are the most commonly prescribed oral treatment for eczema, but do they actually address its symptoms? Dr. Jonathan Silverberg, a dermatologist and researcher with George Washington University, offers some straight talk in this episode of Eczema Breakthroughs. Tune in!
    Research referenced in this podcast:
    Comorbidities and the impact of atopic dermatitis (https://www.annallergy.org/article/S1081-1206(19)30319-9/abstract)
    Use of systemic corticosteroids for atopic dermatitis (https://onlinelibrary.wiley.com/doi/full/10.1111/bjd.15928)
    Increased ADHD symptoms in atopic dermatitis are associated with antihistamine use (https://onlinelibrary.wiley.com/doi/abs/10.1111/all.13326)
    A systemic review of the safety and efficacy of systemic steroids (https://www.ncbi.nlm.nih.gov/pubmed/29032119)
    This podcast was produced in collaboration with the Revolutionizing Atopic Dermatitis (RAD) Conference (https://revolutionizingad.com/) and with support from Sanofi Genzyme and Regeneron.

    • 30 min

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