To Health With That! MTHFR Mutations and Methylation.

Dr. Amy Neuzil
  • 4.9 (49)
  • ALTERNATIVE HEALTH
  • UPDATED WEEKLY

This podcast breaks up BIG health topics, like MTHFR and methylation, into small, easy bites. All in ten minutes or less. We'll discuss why folic acid can be toxic, how the MTHFR enzyme links to estrogen and toxins, why you want to turn genes off, and how folate and mental health are connected. 2024-2025 will add new "bonus" episodes to Season 1 to clarify and revise concepts while Dr. Amy is writing a book. Check linked blogs at tohealthwiththat.com for more info and downloadable. Join us in Genetic Rockstars, our MTHFR, methylation community now at community.tohealthwiththat.com

  1. 1D AGO

    Monica's MTHFR Story - PCOS, Hives, and Histamine

    Monica was kind enough to share her health story with us, starting with a PCOS diagnosis, then thyroid antibodies, then uncontrollable hives, and finally to some relief when she found out about MTHFR and started working on her methylation. This is the full-length interview. MTHFR stories have so much variety, but there are common threads and hormone imbalance, inflammation, and histamine are definitely in there. Thank you so much for being here, Monica!00:00 - Intro and Monica’s PCOS diagnosis01:54 - Hives02:23 - Head to toe Hives02:45 - I’m scared of food03:26 - Discovering MTHFR04:36 - Monica’s supplements06:04 - Folinic acid and anxiety07:25 - Grieving all the time I didn’t know about MTHFR08:06 - Protecting her children’s health09:23 - Eating healthy without overwhelm10:24 - The most helpful things for Monica10:55 - Nervous system health and self-time11:26 - Hives latelyHere is the full-length interview on YouTube. Thank you so much to Monica, who consented to share this content on the podcast and on YouTube.Thanks so much for watching. Here are some links that you might like.The website (and lots of free resources): ⁠https://tohealthwiththat.com⁠FREE MTHFR Basics course: ⁠https://www.tohealthwiththat.com/free-tools⁠

    13 min

  2. FEB 22

    Jesse's MTHFR Story - Mold Injury and Detoxification

    Jesse generously shares his story of MTHFR, chemical sensitivity, and mold injury. Mold illness can affect many people with MTHFR because of our slower detoxification abilities, so mold injury and chemical sensitivity are common threads in the MTHFR journey. Jesse talks about mold remediation, herxheimer reactions, chemical sensitivity, and methylation.00:00 - Intro00:34 - Jesse’s strange symptoms for 20 years with MTHFR01:11 - Testing for Mold Illness01:51 - Jesse’s main mold symptoms02:38 - Carbon monoxide poisoning03:20 - Brain inflammation03:43 - Lots of mold illness with MTHFR03:55 - Mold remediation04:22 - Inflammatory markers going down05:05 - Jesse’s supplements05:50 - Mold is the enemy06:59 - The hardest part of being human16:34 - How Jesse found out about MTHFR to begin with09:51 - Jesse’s next steps10:42 - Herxheimer reactions or Herx reactions You can watch the full-length interview on YouTube here.Thanks so much for watching or listening. Here are some other links that you might like.The website (and lots of free resources): ⁠https://tohealthwiththat.com⁠FREE MTHFR Basics course: ⁠https://www.tohealthwiththat.com/free-tools⁠

    12 min

  3. JAN 18

    Christa's MTHFR Story - Amazing Son Helps Her Son Beat His Developmental Delay

    Christa generously shares the story of how discovering MTHFR and detoxifying completely changed the trajectory of her son's life, and their family's attention to nutrition. Christa's son struggled with communication, attention, memory, sensory issues, and what was diagnosed as developmental delay. Thanks to Christa's hard work with eliminating folic acid and using detoxification support, including zeolites, her son is now thriving.00:00 - Introduction and meet Christa00:49 - Christa's son's struggles - communication, sensitivity, and developmental delay01:39 - The day we knew things weren't normal02:00 - Mom says "This is on me."02:31 - Finding out about MTHFR03:11 - Starting to detox03:29 - Three weeks of no folic acid and zeolites and he was a different kid.03:55 - MTHFR testing comes back positive04:19 - "I've been poisoning my son with fortified foods his whole life"04:40 - He's not struggling, but he's not thriving yet05:35 - I wish every mom knew about this07:02 - No more special needs or developmental delay.08:04 - The ability to express himself08:45 - Getting folic acid out of the way09:31 - Why babies should be tested for MTHFR10:12 - The complicated case of fortified food10:40 - Raising awareness to help other parents11:09 - Making changes for Max has helped the whole householdThanks so much for watching! I have so many other resources for you. Here is the full length version of this interview: https://youtu.be/FVbXxD9WVoQIf you would like to tell your own MTHFR story, you can schedule with Dr. Amy here: ⁠https://calendly.com/amy-tohealthwiththat/new-meeting⁠Check out the website first for lots of FREE stuff:WEBSITE: https://tohealthwiththat.com/ Order Dr. Amy's book MTHFR Easy: Get Healthy For Life: https://amzn.to/47tT31YPaperback and audiobook versions are coming soon.This story was shared graciously and generously with permission to post on the podcast, Youtube, and in print if that happens in the future.

    13 min

  4. 12/21/2025

    Kelsey's MTHFR Story - Hormones, blood sugar and hemochromatosis.

    Today, Kelsey is kind enough to share her and her family's journey with MTHFR. Like the rest of us, their journey has unfolded slowly with a lot of personal research along the way.00:00 - Intro00:38 - Meeting Kelsey01:11 - How she found out about MTHFR02:18 - Quest to learn about MTHFR03:23 - High dose folic acid in pregnancy and pregnancy complications04:09 - The MTHFR highlights - ADHD, difficult fertility, weird pregnancy symptoms, sensitivities.04:39 - Eliminating folic acid, starting gummy multis06:16 - hemochromatosis solutions08:00 - Sugar cravings at night09:01 - Sugar and craving hack with flax seeds09:28 - Fast COMT10:54 - Seed cycling - how to and what to expectThanks so much for watching! I have so many other resources for you. There is also a more extended, unedited version of this interview.If you would like to tell your own MTHFR story, you can schedule with Dr. Amy here: ⁠https://calendly.com/amy-tohealthwiththat/new-meeting⁠Check out the website first for lots of FREE stuff:WEBSITE: https://tohealthwiththat.com/ Order Dr. Amy's book MTHFR Easy: Get Healthy For Life: https://amzn.to/47tT31YPaperback and audiobook versions are coming soon.This story was shared graciously and generously with permission to post on the podcast, Youtube, and in print if that happens in the future.

    14 min

  5. 12/07/2025

    Betsy's MTHFR Story - Rheumatoid Arthritis, methotrexate, and MTHFR

    Season 5, Episode 7 of the To Health With That! podcast. Betsy and I recorded this video several years ago (hence the hair!) and she was kind enough to consent to share it in this format as well. Betsy's history as a nurse gives her a wonderful, insightful perspective on healthcare and her journey with autoimmune disease and having to take an antifolate will help so many other individuals who are struggling with this issue.00:00 - Intro00:36 - Betsy’s Story with Autoimmune disease03:20 - Flexibility is Betsy’s most important thing04:51 - Highly Sensitive People05:36 - MTHFR and perfectionism06:53 - Personal responsibility in MTHFR07:21 - Taking methotrexate with MTHFR (an anti-folate medication)09:11 - Symptom tracking10:53 - Knowledge about your own health is power.Thanks so much for watching! I have so many other resources for you. Here is the full version of this interview: If you would like to tell your own MTHFR story, you can schedule with Dr. Amy here: ⁠https://calendly.com/amy-tohealthwiththat/new-meeting⁠Check out the website first for lots of FREE stuff:WEBSITE: https://tohealthwiththat.com/ Order Dr. Amy's book MTHFR Easy: Get Healthy For Life: https://amzn.to/47tT31YPaperback and audiobook versions are coming soon.This story was shared graciously and generously with permission to post on the podcast, Youtube, and in print if that happens in the future.

    12 min

  6. 11/23/2025

    Kristyn's MTHFR Story - Fatigue, Anxiety, Pericarditis

    Thank you so much to Kristyn for sharing her MTHFR story with us. Kristyn has only known she had an MTHFR gene variant for three months, but it makes sense of many of the symptoms she has had her whole life like fatigue, difficulty sleeping, and anxiety. MTHFR could be contributing to her recurrent pericarditis and kidney disease.Kristyn shares her journey with diet and supplements and trying to balance more energy with more sleep.This story is generously shared with permission to post to Youtube.00:00 - Intro00:44 - Kristyn discovers MTHFR01:04 - Recurrent pericarditis02:04 - Long-standing fatigue02:28 - Anxiety03:36 - Sleep difficulty04:04 - Early menopause with MTHFR and COVID vaccine04:51 - Symptoms but nothing shows up on lab tests05:16 - High protein diet05:54 - Starting supplements with MTHFR07:11 - The balance between having more energy and not disturbing sleep07:39 - Bad reactions to medications08:03 - Arcas for pericarditis09:23 - Seeing signs of MTHFR in other people10:24 - Energy changes with diet10:59 - Possible food sensitivities11:48 - Cayenne pepper for pain13:09 - Thank you, KristynThanks so much for watching! I have so many other resources for you. Here is the full version of this interview: https://youtu.be/DGkmqSwDYkwIf you would like to tell your own MTHFR story, you can schedule with Dr. Amy here: ⁠https://calendly.com/amy-tohealthwiththat/new-meeting⁠Check out the website first for lots of FREE stuff:WEBSITE: https://tohealthwiththat.com/ Order Dr. Amy's book MTHFR Easy: Get Healthy For Life: https://amzn.to/47tT31YPaperback and audiobook versions are coming soon.This story was shared graciously and generously with permission to post on the podcast, Youtube, and in print if that happens in the future.

    14 min

  7. 11/09/2025

    Tony's MTHFR Story Part 2 - Tumors, surgery, and anesthesia with MTHFR

    To Health With That! Podcast Season 5, Episode 5. Thank you so much to Tony for generously sharing his story - the full interview was fabulous and included much more than we could put in one podcast episode, so we broke it into two. In this episode, Tony continues to share with the idea of MTHFR being a rebirth, new information he has about a tumor and his concerns about folate and tumor growth, and questions about MTHFR and anesthesia.00:00 - Introduction00:43 - Manageable steps01:07 - Symptom tracking01:23 - Staying in control (or not).02:03 - MTHFR as a rebirth02:45 - tumor03:10 - folate and tumor growth04:40 - Do we get enough B12 from food06:15 - B12 and lithium rotate07:15 - MTHFR and detox09:42 - mental health struggles and folic acid10:31 - MTHFR and anesthesia11:11 - MTHFR and nitrous oxide and preparing for surgery12:32 - MTHFR and antibiotics13:33 - Building back good gut floraThanks so much for watching! I have so many other resources for you. Here is the full version of this interview: https://youtu.be/SZmHnyCKd8UIf you would like to tell your own MTHFR story, you can schedule with Dr. Amy here: ⁠https://calendly.com/amy-tohealthwiththat/new-meeting⁠Check out the website first for lots of FREE stuff:WEBSITE: https://tohealthwiththat.com/ You can now Pre-order the book MTHFR Easy: Get Healthy For Life. https://www.amazon.com/MTHFR-Get-Started-Guide-Healthy-ebook/dp/B0FLFCY1YQ/ref=sr_1_2?crid=3E616JJOYSA12&dib=eyJ2IjoiMSJ9.7WXbrOZ6vkAu5Ncg9lJLavpPvim_O1kOvqp3LTim_snTq6Gahvu-NhWvC1mZurA6.XnOpY_FYGI_DbfEx9NmEwRrSM2USTXkw_HTykBFrMtw&dib_tag=se&keywords=amy+neuzil&qid=1755710249&sprefix=amy+neuzil%2Caps%2C98&sr=8-2 Look for Kindle, audiobook, and paperback versions also to be released on October 24, 2025.GENETIC ROCKSTARS (an MTHFR, methylation, and genetics community): https://community.tohealthwiththat.comThis story was shared graciously and generously with permission to post on the podcast, Youtube, and in print if that happens in the future.

    16 min

  8. 10/26/2025

    Tony's MTHFR Story - Part I. Anxiety, overwhelm, methyl folate intolerance

    To Health With That! Podcast Season 5, Episode 4. Thank you so much to Tony for generously sharing his story - the full interview was fabulous and included much more than we could put in one podcast episode, so we broke it into two. In this episode, Tony shares his frustration at feeling bad, but doctors telling him he's "normal", the relief at finding MTHFR, which makes his symptoms make more sense, and the beginnings of his journey so far. He talks about brain fog, fears of cognitive decline, overwhelm, and more.00:00 - Introduction00:48 - Tony doesn't feel good, but doctors say he's fine01:18 - Being stuck in the disabled veteran category02:11 - Found out about MTHFR02:27 - Eliminating folic acid03:05 - Methyl folate feels like too much03:21 - Trying B1203:48 - The beginning is hardest with MTHFR04:53 - Methyl-free multivitamin05:42 - Tony's perfect storm of triggers08:07 - MTHFR and blood sugar dysregulation08:33 - Things we wish we knew when we were young09:33 - Brain fog or cognitive decline10:55 - Overwhelm and high sensitivity13:03 - Highly sensitive person as a form of neurodiversity14:27 - Not alone in this. hanks so much for watching! I have so many other resources for you.  Here is the full version of this interview: https://youtu.be/SZmHnyCKd8U If you would like to tell your own MTHFR story, you can schedule with Dr. Amy here: ⁠https://calendly.com/amy-tohealthwiththat/new-meeting⁠ Check out the website first for lots of FREE stuff: WEBSITE: https://tohealthwiththat.com/  You can now Pre-order the book MTHFR Easy: Get Healthy For Life. https://www.amazon.com/MTHFR-Get-Started-Guide-Healthy-ebook/dp/B0FLFCY1YQ/ref=sr_1_2?crid=3E616JJOYSA12&dib=eyJ2IjoiMSJ9.7WXbrOZ6vkAu5Ncg9lJLavpPvim_O1kOvqp3LTim_snTq6Gahvu-NhWvC1mZurA6.XnOpY_FYGI_DbfEx9NmEwRrSM2USTXkw_HTykBFrMtw&dib_tag=se&keywords=amy+neuzil&qid=1755710249&sprefix=amy+neuzil%2Caps%2C98&sr=8-2   Look for Kindle, audiobook, and paperback versions also to be released on October 24, 2025. GENETIC ROCKSTARS (an MTHFR, methylation, and genetics community): community.tohealthwiththat.com This story was shared graciously and generously with permission to post on the podcast, Youtube, and in print if that happens in the future.

    16 min
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About

This podcast breaks up BIG health topics, like MTHFR and methylation, into small, easy bites. All in ten minutes or less. We'll discuss why folic acid can be toxic, how the MTHFR enzyme links to estrogen and toxins, why you want to turn genes off, and how folate and mental health are connected. 2024-2025 will add new "bonus" episodes to Season 1 to clarify and revise concepts while Dr. Amy is writing a book. Check linked blogs at tohealthwiththat.com for more info and downloadable. Join us in Genetic Rockstars, our MTHFR, methylation community now at community.tohealthwiththat.com

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